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Heritable genome-wide variation of gene expression and promoter methylation between
Heritable genome-wide variation of gene expression and promoter methylation between

... removed for extraction of both DNA and mRNA. For the offspring, eight pools of both were prepared, each consisting of six same-sex samples within families. Hence, there were in total eight parental single-animal samples, and eight pools of offspring samples. The mRNA was hybridized to a 38K Affymetr ...
New Gene for Bacterial Blight Resistance in Rice Located
New Gene for Bacterial Blight Resistance in Rice Located

... Pi-ta2 (2). These results suggest that there is at least one multiple gene family for disease resistance in the centromeric region of chromosome 12. Pi-ta encodes the NBS-LRR type protein (1). The present study also located two closely linked NBS sequences to the centromeric region of chromosome 12. ...
Interacting Gene Clusters and the Evolution of the Vertebrate
Interacting Gene Clusters and the Evolution of the Vertebrate

An Empirical Test for Branch-Specific Positive Selection
An Empirical Test for Branch-Specific Positive Selection

... with nested null models to test whether positive selection might be occurring at a subset of sites (codons) on the human lineage by comparison of results from model A vs. model A-null (‘‘strict branch-site test’’) and model A vs. model 1a (‘‘relaxed branch-site test’’). The strict branch-site test r ...
Chapter 15
Chapter 15

... Chapter 15: The Chromosomal Basis of Inheritance 1. How was it determined that chromosomes carry genes? 2. Morgan’s next cross showed that linked genes are inherited together. 3. What if the genes were unlinked…meaning independent assortment? 4. How often will recombination occur…frequency?? 5. How ...
Mitochondria tutorial
Mitochondria tutorial

... genomics resource maintained by The Institute for Genomic Research (TIGR) called the Comprehensive Microbial Resource (CMR). The CMR is a tool that provides access to all of the bacterial genome sequences completed to date. Let's begin by going to TIGR's CMR homepage at http://www.tigr.org/tigr-scri ...
iTagPlot: an accurate computation and interactive drawing tool for
iTagPlot: an accurate computation and interactive drawing tool for

Expressed Sequence Tag (EST)
Expressed Sequence Tag (EST)

chapter 15 - Issaquah Connect
chapter 15 - Issaquah Connect

... of the genetic loci along a particular chromosome and hypothesized that the frequency of recombinant offspring reflected the distance between genes on a chromosome.  Sturtevant predicted the farther apart two genes are, the _________ the probability a crossover will occur, and therefore, the higher ...
Genomic instability — an evolving hallmark of cancer
Genomic instability — an evolving hallmark of cancer

... mutated in two cases each. Last, the HR gene BRCA1, the BeR gene XRCC1, the NeR gene XPD (also known as ERCC2) and the mitotic checkpoint genes BUB1 and STK12 (also known as AURKB) were mutated in one case each (TABLE 1). In the glioblastomas, the frequency of mutations differed dramatically between ...
B. Intralocular Interactions
B. Intralocular Interactions

... This locus makes the ‘H substance’ to which the sugar groups are added to make the A and B surface antigens. A non-function ‘h’ gene makes a nonfunctional foundation and sugar groups can’t be added – resulting in O blood regardless of the genotype at the A,B,O locus. This ‘O’ is called the ‘Bombay P ...
the human y chromosome, in the light of evolution
the human y chromosome, in the light of evolution

Characterization of the trans-spliced transcriptome and polycistronic
Characterization of the trans-spliced transcriptome and polycistronic

... that comprise three or four cistrons. A large number of Echinococcus PTU is also present with similar st ructure in S. mansoni. These data indicate that many PTU were already formed early in flatworm evolution and we indeed obtained evidence that PTU are also present in planarians. Within flatworm P ...
Modeling Disease Evolution with Multilevel Selection: HIV as a
Modeling Disease Evolution with Multilevel Selection: HIV as a

... Social heterosis is a potentially powerful evolutionary process when two preconditions are met [60, 61]. First, the organism’s environment must be complex or heterogenous so that no single genotype can optimally exploit every aspect of it. Second, populations must be subdivided into interacting grou ...
Title: Evolution of dosage compensation in Anolis carolinensis, a
Title: Evolution of dosage compensation in Anolis carolinensis, a

... (Vicoso et al. 2013), silkworms (Xingfu 2009), and the flatworm Schistosoma mansoni (Vicoso and Bachtrog 2011). However, it is unknown whether the limited number of taxa that have been studied to date biases perceived trends about dosage compensation. For example, the ZZ/ZW moth Manduca sexta has be ...
Phylogeny (ch 26) Campbell PPT
Phylogeny (ch 26) Campbell PPT

... • A shared ancestral character is a character that originated in an ancestor of the taxon • A shared derived character is an evolutionary novelty unique to a particular clade • A character can be both ancestral and derived, depending on the context ...
Genetic Characterization of Insulin Growth Factor
Genetic Characterization of Insulin Growth Factor

... The improvement of buffalo productivity has been dependent on DNA and genetic markers that are associated with various productivity traits of economic importance to promote more efficient and relatively easy selection of Egyptian buffaloes with an advantage for inheritable traits. Most productivity ...
Chapter 26
Chapter 26

... • A shared ancestral character is a character that originated in an ancestor of the taxon • A shared derived character is an evolutionary novelty unique to a particular clade • A character can be both ancestral and derived, depending on the context ...
Phylogeny and the Tree of Life
Phylogeny and the Tree of Life

... • A shared ancestral character is a character that originated in an ancestor of the taxon • A shared derived character is an evolutionary novelty unique to a particular clade • A character can be both ancestral and derived, depending on the context ...
reported several instances of so-called " complex genes ", whose
reported several instances of so-called " complex genes ", whose

Immunogenetics
Immunogenetics

...  Why did the amino acid sequencing of antibody light chains lead Dryer and Bennet to abandon the one gene- one polypeptide theory and propose that two genes code for a single polypeptide? ...
Detection of Bacterial Pathogens in River Water Using Multiplex-PCR
Detection of Bacterial Pathogens in River Water Using Multiplex-PCR

... 1.2 Methods used in detection of bacterial pathogens in water Detection, differentiation, and identification of bacteria can be performed by numerous methods, including phenotypic, biochemical and immunological assays, and molecular techniques. These traditional methods for the detection and enumera ...
An early dihybrid cross
An early dihybrid cross

... In fact, we can define one genetic map unit (m.u.) as that distance between genes for which one product of meiosis in 100 is recombinant. Put another way, a recombinant frequency (RF) of 0.01 (1 percent) is defined as 1 m.u A map unit is today referred to as a centimorgan (cM) in honor of Morgan A d ...
Alternative Splicing A very short introduction (in plants)
Alternative Splicing A very short introduction (in plants)

... Genome-wide analyses of alternative splicing in plants: Opportunities and challenges Genome Res. 2008. 18:1381-1392 ...
Comparison of Microarray Pre-Processing Methods
Comparison of Microarray Pre-Processing Methods

... analyze the false discovery rate. From the dispersion analysis, we found that variability is reduced more effectively by LWPM and RMA methods. From the false positive analysis, and for both parametric and non-parametric approaches, LWMM is found to perform best. Based on a complementary q-value anal ...
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Pathogenomics

Pathogen infections are among the leading causes of infirmity and mortality among humans and other animals in the world. Until recently, it has been difficult to compile information to understand the generation of pathogen virulence factors as well as pathogen behaviour in a host environment. The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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