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The genome organisation of vertebrates
The genome organisation of vertebrates

... deoxyribonucleic acid (DNA), which is made up of two complementary strands wound around each other to form a double helix (Fig. 1). The building blocks of each DNA strand are deoxyribonucleotides. These are formed by a phosphate ester of deoxyribose (a pentose sugar), linked to one of four bases: tw ...
Supplemental Figure and Methods
Supplemental Figure and Methods

... of the nine resulting lists by the strength of their biological evidence; MGD, GO biological process, and UniProt data were considered to have the strongest biological evidence and were weighted highest. The weighted scores across all lists were then summed together for each gene to provide a final ...
doc
doc

... gene coding for the enzyme was cloned by LA-PCR. The gene could highly expressed in E. coli using pET expression system. The specific activity of recombinant enzyme was 27-fold higher than that of the original Sinorhizobium morelens S-5 strain. The enzyme was a homotetramer with a native molecular m ...
MMG 232: Methods In Bioinformatics Spring 2016, 3 credits
MMG 232: Methods In Bioinformatics Spring 2016, 3 credits

... This course provides a methodological survey of bioinformatics techniques. Particular emphasis is given to popular bioinformatics applications. Classes will include about an hour of theory/background, followed by an hour of hands on bioinformatics tool application at your laptop. Lastly we will sum ...
Gene Concept - Govt. College Aron
Gene Concept - Govt. College Aron

... messenger RNA, uracil nucleotides are removed and cytocine nucleotides are replaced by uracil after transcription. The information for this process comes either from the gene involved or alternatively from outside it ...
Genetics
Genetics

... to humans. Some examples of genes in humans would be the genes for: ...
Gene Enrichment Analysis
Gene Enrichment Analysis

... manually. Many tools exist for assessing signicance of enrichment within a group. These typically employ hypergeometric (TANGO) testing, but can also be based on a KolmogorovSmirnov statistic (GSEA). These tools usually require empirical estimations of p-values and multiple testing corrections. GSE ...
000 EXAM 2 study guide
000 EXAM 2 study guide

... 6. Understand the implications of these mutations: silent, missense, nonsense. 7. Understand an open reading frame. Example problem 8.14. If you have a piece of doublestranded DNA that does not have any stop codons, how many open reading frames do you have? 8. Understand the terms: template strand, ...
the marine viral haemorrhagic septicaemia virus
the marine viral haemorrhagic septicaemia virus

... By gaining a better understanding of the molecular basis for the pathogenicity of VHS viruses this project seeks to establish if the concerns regarding the adaptation and a possible increase in the pathogenicity of marine VHSV strains for cultivated fish species are justified. Genetic manipulation o ...
A Genome-Wide Association Study of Inbred Rat Strains
A Genome-Wide Association Study of Inbred Rat Strains

Ensembl gene annotation project (e!76) Homo sapiens (human
Ensembl gene annotation project (e!76) Homo sapiens (human

... Protein and cDNA sequences for human were downloaded from public databases (UniProt SwissProt/TrEMBL [8] and RefSeq [9] for proteins and ENA/Genbank/DDBJ and RefSeq [9] for cDNAs). We filtered the human protein and cDNA input sequences, for example by excluding sequences labelled as PE 3,4, or 5 by ...
genes, pseudogenes, deletions, insertion elements and DNA islands
genes, pseudogenes, deletions, insertion elements and DNA islands

Genetics and Probability
Genetics and Probability

... Mendel’s work laid the foundation for an understanding of inheritance. However, it’s clear his work explaining traits with two alleles, one dominant, one recessive, represent just one possible type of inheritance. Some traits are determined by multiple genes; this is polygenic inheritance. In these ...
Document
Document

... chromosomes, one of each pair from the male parent and the other of each pair from the female parent. Twenty-two of these pairs are autosomes. Autosomes are chromosomes that contain genes for the same traits. The twenty-third pair of chromosomes are sex chromosomes. Females inherit two X chromosomes ...
Document
Document

... oxygen levels are often variable. Aquaculture could be greatly benefitted if animals are developed that can withstand hypoxic stress. It would also be important to know if this gene has any relationship with growth, to determine whether normal growth is affected during prolonged periods of hypoxia. ...
11-3: exploring mendelian genetics
11-3: exploring mendelian genetics

Microarray-based Disease Prognosis using Gene Annotation
Microarray-based Disease Prognosis using Gene Annotation

... Tryptophan catabolism ...
Biology 6 Practice Genetics Problems (chapter 15)
Biology 6 Practice Genetics Problems (chapter 15)

... If crossing over occurs 100% of the time between two linked genes, the result is 50% recombinant chromosomes in gametes and 50% parental chromosomes (as revealed by a test cross). This would be the case only if the genetic loci are at opposite ends of a chromosome, which produces the same basic outc ...
ucsc genome research primer - Center for Biomolecular Science
ucsc genome research primer - Center for Biomolecular Science

Lecture 28
Lecture 28

... 1. Most microorganisms (cells, actually) are totipotent and can produce many different kinds of gene products and in large quantities. Most microorganisms (cells) don’t produce all the gene products of which they are capable for the logical reason of energy conservation. For example, most microorgan ...
Ribosomal DNA sequences reveal gregarine pathogens
Ribosomal DNA sequences reveal gregarine pathogens

... proposed approach is able to detect taxa for which no sequence data are available. There is very little information available concerning the eukaryotic pathogens or endosymbiots of Arachnida, especially Acari. This is, to our knowledge, the second report of Astigmata infected with gregarines (Loo et ...
ISMB2008PosterManagingGenomicData
ISMB2008PosterManagingGenomicData

... GMOD is a collection of interoperable open-source software components for managing, visualizing and annotating genomic data. GMOD components are used at hundreds of organizations, ranging from major model organism databases to individual labs. GMOD is well positioned to serve the converging interest ...
Name - O. Henry Science
Name - O. Henry Science

... child. For example, maybe both parents have brown eyes. Let's say that they each have one gene for brown eyes (B) and one gene for blue eyes (b). Brown eyes are dominant over blue eyes. That's why both the parents have brown eyes, even though they carry a gene for blue eyes. The gene for blue eyes i ...
The Family of MADS – Box Genes Controlling Flower Development
The Family of MADS – Box Genes Controlling Flower Development

... genes were isolated from Crocus sativus L. The sequence alignment revealed that the five CsPI proteins contain the typical domain structure of plant MADS box proteins consisted of the conserved N-terminal MADS-box, the I domain, the central K domain and the C terminal domain. In Arabidopsis, express ...
ab initio and Evidence-Based Gene Finding
ab initio and Evidence-Based Gene Finding

... Model rules using a finite state machine (FSM) Use species-specific characteristics to improve the accuracy of gene predictions Distribution of exon and intron sizes Base frequencies (e.g., GC content, codon bias) Protein sequences from the same or closely related species ...
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Pathogenomics

Pathogen infections are among the leading causes of infirmity and mortality among humans and other animals in the world. Until recently, it has been difficult to compile information to understand the generation of pathogen virulence factors as well as pathogen behaviour in a host environment. The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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