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Bioinformatics
Bioinformatics

... • the Unique Human Gene Sequence Collection, • a Gene Map of the human genome, a Taxonomy Browser, and coordinates with the National Cancer Institute to provide the Cancer Genome Anatomy Project. • The NCBI assigns a unique identifier (Taxonomy ID number) to each species of organism. • The NCBI has ...
A Variable Number of Tandem Repeats Locus with!, the Human
A Variable Number of Tandem Repeats Locus with!, the Human

... have been detected, characterized by SstI fragments of 2.75, 2.70, 2.65, 2.60, or 2.50 kb corresponding to BamHI fragments of 3.45, 3.40, 3.35, 3.30, or 3.20 kb (3, 5). The distribution of these alleles among 143 unrelated individuals was found to be skewed with 250 (87.4%) chromosomes having 2.70/3 ...
Meet the Fly
Meet the Fly

... assortment of genes on the same chromosome. Whenever there is a crossing over event between two genes on the same chromosome, gametes are going to be generated that resemble the recombinant type (see previous examples). If the frequency of crossing over is as common as 50%, then alleles at the two g ...
Genes Identified by Visible Mutant Phenotypes Show Increased Bias
Genes Identified by Visible Mutant Phenotypes Show Increased Bias

... subgenome is significantly greater than for the classical maize gene list as a whole (p = .028, Fisher Exact Test), and members of homeologous gene pairs located on maize1 were twice as likely as the duplicate copies on maize2 to be originally identified by mutant phenotype -- 29 maize1 genes with h ...
MCDB 1041 Activity 3: Thinking about how “linkage” affects the
MCDB 1041 Activity 3: Thinking about how “linkage” affects the

Sordaria Meiosis and Crossing Over Lab Name Objective: To
Sordaria Meiosis and Crossing Over Lab Name Objective: To

Evolution of multicellularity and sexuality in the life cycles of
Evolution of multicellularity and sexuality in the life cycles of

... in the major lineages of red, green, and brown plants. Completed genomic sequences are newly available (and more are rapidly becoming available) for representative unicellular and multicellular species from the major photosynthetic lineages. Therefore, it has now become possible to address the grand ...
Distinguishing coding from non-coding sequences in a prokaryote
Distinguishing coding from non-coding sequences in a prokaryote

Simple and efficient method for isolating cDNA - Funpec-RP
Simple and efficient method for isolating cDNA - Funpec-RP

... kDa) proteins, that are involved in protecting higher plants from damage caused by environmental stress especially drought. Based on their amino acid sequences, LEA proteins are basically divided into five groups (Dure, 1993; Zhang and Zhao, 2003). To date, there have been some reports about the lea ...
Human housekeeping genes are compact
Human housekeeping genes are compact

... trimmed average expression level in each tissue in accordance with the standard Affymetrix normalization procedure [11,12]. Thus, our HK genes are expressed in all tissues at an above-average level. A histogram (Fig. 1a) of the number of genes expressed in exactly M of the 47 tissues shows a clear t ...
Sequencing a genome and Basic Sequence Alignment
Sequencing a genome and Basic Sequence Alignment

... sites : vary in size from sites of 4bp to 8bp or longer; 4 bp cuts into fragments of 256 bp in size ; of 8 b.p 4 8 (64,000) b.p. ; e.g. ...
Ciliated dendrite mRNA may control olfactory sensory neuron
Ciliated dendrite mRNA may control olfactory sensory neuron

... the translocon complex). We found that the five genes expressed at the same levels in OSN cilia from seven different animals. Consistent with the unique features of OSN, i.e. brain-environment interface and activity-dependent survival, functional analysis of all ONCL genes revealed that more than ha ...
CHAPTER 24 Molecular Evolution
CHAPTER 24 Molecular Evolution

... c. Evolutionary trees were constructed for many groups of plants and animals, and these continue to provide a basis for evolutionary study. ...
2001_butterfield_THE SUGARCANE GENOME
2001_butterfield_THE SUGARCANE GENOME

... race-specific resistances. Although good conservation of RFLP marker order in grasses has been demonstrated over large chromosomal segments (Devos and Gale, 1997), several disease resistance genes are not well conserved and may prove difficult to identify through comparative analysis (Keller and Feu ...
The Evolution of tRNA-Leu Genes in Animal
The Evolution of tRNA-Leu Genes in Animal

... amino acid. In the standard genetic code, Arginine also has a four- and a two-codon family. However, in mitochondria, the two codon family is either used as stop codons or reassigned to form a four codon Serine family. The L and L2 genes on the mitochondrial genome of any one species must, by defini ...
Understanding fermentation batch variability through whole genome
Understanding fermentation batch variability through whole genome

Adaptive evolution in invasive species
Adaptive evolution in invasive species

... with high visibility to selection [43], and these changes might promote invasiveness in some neo-allopolyploids. Recent studies demonstrate, however, that hybridization has a greater effect than chromosome doubling on genomic changes in allopolyploids [42]. Thus, hybridization could be more importan ...
Sequence Alignment - Faculty of Science at Bilkent University
Sequence Alignment - Faculty of Science at Bilkent University

... thought to proliferate by amplification of an extremely small number of "master" genes. These genes usually give rise to inactive copies (truncated at the 5' end) that are incapable of further transposition within the genome. The defective copies arise because of their mode of transposition through ...
Adaptive evolution in invasive species
Adaptive evolution in invasive species

... with high visibility to selection [43], and these changes might promote invasiveness in some neo-allopolyploids. Recent studies demonstrate, however, that hybridization has a greater effect than chromosome doubling on genomic changes in allopolyploids [42]. Thus, hybridization could be more importan ...
Rare genomic changes and mitochondrial sequences
Rare genomic changes and mitochondrial sequences

... have also proven to be phylogenetically informative within some groups, such as ticks (Murrell et al., 2003) and spiders (Masta and Boore, 2008). Besides potentially providing new types of genome structure characters for making phylogenetic inferences, mitochondrial genomes provide a rich source of ...
portable document (.pdf) format
portable document (.pdf) format

... ROC curves by choosing different thresholds for gene calls. I repeat the process for 50 times. Each point on the ROC curves is the average of 50 true/false positive rates when I select a same value for the gene call. Figure 1 shows the estimated true/false-positive rates based on 50 simulations. Whe ...
The new genes of rice: a closer look
The new genes of rice: a closer look

... of this kind would suggest that a large proportion of the NH proteins are non-functional and/or that NH proteins tend to be much less widely or frequently expressed than other rice proteins. In view of the difficulties in experimentally checking the predicted protein set of rice, re-scrutiny of exis ...
Sample Chapter
Sample Chapter

... or markers, or unknown DNA or genes. These maps provide information about the physical organization of the DNA; examples are the location of restriction enzyme sites and the order of restriction fragments of chromosomes. An entire genome can be studied using a library of genomic DNA. These clones ar ...
Bioinformatic Resources, Challenges, and
Bioinformatic Resources, Challenges, and

... all PCR-based markers, and/or to those that show a polymorphism between a chosen pair of ecotypes. Genes can be searched by open reading frame name, gene symbol, full name, or product name. In addition, gene searching can be limited to those genes whose structures have been experimentally determined ...
Gene duplication
Gene duplication

... Gene duplication may be three variable tpyes: Complete gene duplication, partial gene duplication and dispersed gene duplication. Long MY, et al. Nat Rev Gent. 2003 Cardoso-Moreira M and Long MY. 2004 ...
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Pathogenomics

Pathogen infections are among the leading causes of infirmity and mortality among humans and other animals in the world. Until recently, it has been difficult to compile information to understand the generation of pathogen virulence factors as well as pathogen behaviour in a host environment. The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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