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AP & Regents Biology
AP & Regents Biology

... Bioinformatics is a great way to learn biology  Using computers to study primary biological data (genomes, proteins, ...
Identification of the equine herpesvirus type 1 glycoprotein 17/18 as
Identification of the equine herpesvirus type 1 glycoprotein 17/18 as

... The presence in EHV-1 of a gene homologous to HSV-1 gD was confirmed by sequence analysis of the DNA upstream of the gI and gE genes (Audonnet et al., 1990; Elton et al., 1991 b). The complete nucleotide sequence of the EHV-1 strain Abl gD homologue was obtained from both strands of the D N A by seq ...
Infectious agents - IARC Publications
Infectious agents - IARC Publications

... easily with these assays. Crossreactivity, or high background staining in cellular material examined microscopically, can also generate false-positive results. The specificity of the antibody is influenced by the presence of non-microbial antigenic ...
Transplantation Immunology pg. 1 Laura Rayne Today I`m going to
Transplantation Immunology pg. 1 Laura Rayne Today I`m going to

... DNA, which is much smaller, circular, and is often found with many copies. These plasmids may contain antibiotic resistance markers. This (the diagram) is an example of the whole genome of m. tuberculosis. Now they have fancy technologies that allow sequencing of an entire genome within a couple of ...
Recent Statistical Approaches
Recent Statistical Approaches

... 1) Form a statistic tj for each gene, where a large positive value of tj corresponds to a gene that is differentially expressed across the tissues. 2) Compute the Pj-values according to the tj and fit a mixture of beta distributions (including a uniform component) to them where the latter correspon ...
DNA Vaccines Non-Amplifiable in Eukaryotic cell for
DNA Vaccines Non-Amplifiable in Eukaryotic cell for

... be discussed and the sequence of the wild-type gene and the antigenic properties of the encoded protein in its natural state should be provided. The steps in the construction of the entire vaccine plasmid should be described, including the source of the plasmid(s) used and subclones generated during ...
Document
Document

... the incidence of antibiotic resistance which may limit our therapeutic choices in future, polysaccharide based vaccines could provide an attractive alternative as they are not modified by mutations. In this context, a database compiling all the antigenic polysaccharides becomes an urgent need as it ...
PowerPoint from Class - Bryn Mawr School Faculty Web Pages
PowerPoint from Class - Bryn Mawr School Faculty Web Pages

... Saccharomyces cerevisiae (below): favorite organisms of gene research ...
Pattern of diversity in the genomic region near the
Pattern of diversity in the genomic region near the

... http:兾兾evolve.zoo.ox.ac.uk). Molecular population genetic statistics were estimated by using the software DNASP, Version 3.51 (26), unless otherwise noted. For the Hudson–Kreitman– Aguade (HKA) test, the Z. diploperennis sequence was used to calculate divergence, and adh1 (25, 27), adh2 (28), te1 (2 ...
Supplementary Figures (doc 9746K)
Supplementary Figures (doc 9746K)

... gene annotation. The only difference is that the new junction group uses different combinations of start and stop sites. The 3rd and 4th categories are junctions having new 3’ stop sites (acceptor site) or 5’ start sites (donor site). The 5th and 6th categories are junctions whose splice sites are b ...
Origin and Evolution of the Mitochondrial Aminoacyl
Origin and Evolution of the Mitochondrial Aminoacyl

... This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is proper ...
No Slide Title - Brigham Young University
No Slide Title - Brigham Young University

... SOMs are unsupervised neural net algorithms that identify coregulated genes Page 211 ...
Primer on Molecular Genetics
Primer on Molecular Genetics

... information required for constructing proteins, which provide the structural components of cells and tissues as well as enzymes for essential biochemical reactions. The human genome is estimated to comprise at least 100,000 genes. Human genes vary widely in length, often extending over thousands of ...
mv-lect-06-virus-repl-stratigies
mv-lect-06-virus-repl-stratigies

... These viruses replicate their genomes via one of two unique biochemical pathways: • RNA-dependent RNA synthesis (RNA replication), • RNA-dependent DNA synthesis (reverse transcription) followed by DNA replication and transcription. Both pathways require enzyme activities that are not usually found i ...
Tiger beetles - Discover the Microbes Within!
Tiger beetles - Discover the Microbes Within!

... the life cycle of the 2 beetles. One paper found that in one species of tiger beetles found in the flood plains of a part of the Peruvian Amazon the life cycles for males and females differed, and the males had a shorter lifespan than the females. (Amorim et al, 1997) Though I don’t know yet if the ...
Final Project Jocelyn Hansson Global Alignment with Affine Gap
Final Project Jocelyn Hansson Global Alignment with Affine Gap

... social processes such as bonding and maternal behavior. I thought comparing this gene across species would be useful in order to justify using such a model. In my comparisons I aimed to find out how similar the mouse and human OXTR genes are. Is the sequence largely conserved between the spec ...
Pathogens in the Environment
Pathogens in the Environment

... simplest (nucleic acid + protein coat (+ lipoprotein envelope) spherical (icosahedral) or rod-shaped (helical) no biological activity outside of host cells/or host organisms – obligate intracellular parasites; recruit host cell to make new viruses, often destroying the cell • non-enveloped viruses a ...
publication
publication

... demand for effective analysis, annotation and display of large single genomic sequences, new tools for displaying comparative sequence analysis are just beginning to emerge. These programs include CGAT (15), Intronerator (16,17) and Alfresco (18). In this paper we introduce a program called Laj (loc ...
A natural chimeric yeast containing genetic material from three species
A natural chimeric yeast containing genetic material from three species

... between these two species (Nicoletti et al., 1994 ; Ooi et al., 1985). The ATP9 genes in the isolates analysed were also found to be 228 bp long (Fig. 2). The amino acid sequences were identical in all cases, but several silent substitutions were observed. The ATP9 gene sequences of Saccharomyces sp ...
Background and Overview of Comparative Genomics
Background and Overview of Comparative Genomics

... are derived from the majority noncoding and therefore more variable class of DNA (type I markers). However, these highly polymorphic markers are of very limited use for comparisons between genomes because their variability makes it impossible to detect homology across species. Although they may be e ...
Polymorphisms of the PSD3 gene are associated with obesity in two
Polymorphisms of the PSD3 gene are associated with obesity in two

... PSD3 gene polymorphisms with obesity in two Caucasian samples, providing a basis for replication in other populations to elucidate the potential role of these genetic variants. Future functional study of this gene may help to better characterize the genetic architecture of obesity. ...
Japanese Journal of Ophthalmology Vol.47 No.3
Japanese Journal of Ophthalmology Vol.47 No.3

... The novel Asp123His (D123H) mutation was identified in the patient with atypical GCD and in three of five unaffected family members, and thus was not cosegregated with the phenotype in the family studied. The D123H mutation may be one of the rare polymorphisms; however, the fact that it was absent i ...
Spontaneous Generation
Spontaneous Generation

... organisms arise from preexisting life, is called biogenesis. (Rudolf Virchow) ...
MENDEL MEETS CSI: Forensic Genotyping as a Method To Teach
MENDEL MEETS CSI: Forensic Genotyping as a Method To Teach

... To extract DNA from buccal cells, sterile cotton swabs, a boiling water bath, and a micro-centrifuge are needed. The cell lysate obtained is crude and contains heavy metal ions that can interfere with PCR amplification by either inhibiting DNA polymerase or by acting as cofactors for nucleases that ...
Slide 1
Slide 1

... Notably, every data source is positively correlated with the overall prioritization order (“Overall prioritization” in the figure), indicating that every data source contributes to the overall prioritization order. A small correlation between the data sources is only observed for the related data so ...
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Metagenomics



Metagenomics is the study of genetic material recovered directly from environmental samples. The broad field may also be referred to as environmental genomics, ecogenomics or community genomics. While traditional microbiology and microbial genome sequencing and genomics rely upon cultivated clonal cultures, early environmental gene sequencing cloned specific genes (often the 16S rRNA gene) to produce a profile of diversity in a natural sample. Such work revealed that the vast majority of microbial biodiversity had been missed by cultivation-based methods. Recent studies use either ""shotgun"" or PCR directed sequencing to get largely unbiased samples of all genes from all the members of the sampled communities. Because of its ability to reveal the previously hidden diversity of microscopic life, metagenomics offers a powerful lens for viewing the microbial world that has the potential to revolutionize understanding of the entire living world. As the price of DNA sequencing continues to fall, metagenomics now allows microbial ecology to be investigated at a much greater scale and detail than before.
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