• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Sickle cell / mutations
Sickle cell / mutations

... 2. Unlike popular misconceptions about people with green skin or extra body parts, a mutation is simply a change in the nucleotide sequence, or base pair sequence, of DNA. Most mutations are either neutral (they have no effect) or harmful, but occasionally mutations can actually cause a helpful chan ...
F. Mutation and Repair 1. Background on DNA Mutations
F. Mutation and Repair 1. Background on DNA Mutations

Chapter 5
Chapter 5

... advancing complexity of living organisms. 1. The idea is that during meiosis in sexually reproducing organisms, crossover mutations can form multiple copies of a gene, a chromosome or the entire genome. 2. The organism survived just fine with one copy so it only repairs damages (mutations) to one co ...
Effects of diet on genes for cholesterol and lipid metabolism
Effects of diet on genes for cholesterol and lipid metabolism

... LDL Receptors in Guinea Pigs ...
Grant IGA MZČR 8563-5/2005 Genetický profilů genů metabolismu
Grant IGA MZČR 8563-5/2005 Genetický profilů genů metabolismu

... Chapter 16: Cancer genetics and genomics: Oncogenes, Tumorsuppressor genes (including Retinoblastoma,Caretaker genes in autosomal recessive chromosome instability syndromes, Cytogenetic changes in cancer, Gene amplification) Chapter 6: Principles of clinical cytogenetics:Mendelian disorders with cyt ...
Chapter 12 Notes - Great Neck Public Schools
Chapter 12 Notes - Great Neck Public Schools

... XXII. DNA technology raises important ethical questions A. Should we be creating new organisms and adding them to the environment? B. Should we be modifying our own species? C. What will be the implications to the ecosystem? D. For what will we use this technology…medicine or war? E. Who will benefi ...
Model organisms and mutants
Model organisms and mutants

... Model organisms • Selected by researchers based on some feature that renders it particularly useful for studying the genetic process of interest to that researcher. • Each model organism usually has a database and a community of researchers ...
The Sequence Manipulation Suite—a collection of JavaScript prog
The Sequence Manipulation Suite—a collection of JavaScript prog

... written in JavaScript, execute slowly in certain Web browsers. To address this problem, and to provide features difficult to implement in JavaScript, some of the more popular utilities have been rewritten in Perl. These have been combined into a new program called Sequence Extractor, which can be ac ...
Introduction to Seed Development/Arabidopsis as a model organism
Introduction to Seed Development/Arabidopsis as a model organism

TRASK Zool 3200: Cell Biology Exam 2
TRASK Zool 3200: Cell Biology Exam 2

... that contribute to this expression pattern. Assume that a single and unique transcription factor binds to each  site such that protein X binds site A, protein Y binds site B, and protein Z binds site C. You want to determine  which region is responsible for the observed tissue‐specific expression, a ...
Lambda Gene Family
Lambda Gene Family

... formation of a huge library. Or repertoire of B lymphocytes that contain all the specificities required to deal with the multitude of diverse epitopes that antibodies could encounter. The number of total Ig specificities that can be generated in an individual are on the order of 1015 which is increa ...
Epigenomics Workshop - Institute for Systems Genomics
Epigenomics Workshop - Institute for Systems Genomics

... Lynch syndrome (LS). LS is caused by germline mutations in the genes of the DNA mismatch repair (MMR) pathway. His laboratory uses a variety of approaches to unravel the molecular mechanism of the MMR pathway and how defects in this pathway give rise to cancer. This work involves biochemical and bio ...
Genomics - Dr Hub Zwart
Genomics - Dr Hub Zwart

... accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers 99% of the euchromatic genome and is accurate to an error rate of 1 event per 100,000 bases. M ...
All things in moderation – an exploration of GMOs and their pros and
All things in moderation – an exploration of GMOs and their pros and

... • A transgenic organism contains a gene or genes which have been artificially inserted instead of acquiring these through “normal” processes • The inserted gene sequence (transgene) may come from another similar or unrelated organism ...
UNRAVELING THE DNA MYTH The spurious foundation of genetic
UNRAVELING THE DNA MYTH The spurious foundation of genetic

... to answer that question. It hypothesizes a clear-cut chain of molecular processes that leads from a single DNA gene to the appearance of a particular inherited trait. The explanatory power of the theory is based on an extravagant proposition: that the DNA genes have unique, absolute, and universal c ...
Human Genome
Human Genome

... – Tissues are damaged and severe weakness. – Linked to malaria in Africa. – Only 1 DNA base is changed in the allele. – Codominant allele. ...
PROPOSED CURRICULUM IN ZOOLOGY FOR B.Sc., (UG) VI
PROPOSED CURRICULUM IN ZOOLOGY FOR B.Sc., (UG) VI

... d. Blood typing e. Preparation of Buccal smear for sex chromatin f. Preparation of Blood smear for identification of Cell types and to comment on the types of leucocytes. g. Differential counting of blood cells using haemocytometer. h. Micrometry of cell types. Biotechnology: i. Staining and identif ...
Web resources
Web resources

... yeast, the eukaryotic flavor of life is of special interest. What is true of fundamental eukaryotic processes in yeast will be conserved on other eukaryotes. Therefore upon finding a function for a gene/protein in yeast, one wants to know if similar genes/proteins are present in other organisms. Con ...
Proteomics of the chloroplast to chromoplast transition
Proteomics of the chloroplast to chromoplast transition

... cataloguing changes in the proteome during the transition chloroplast/chromoplast; identifying which isoform of the enzyme families are present in the chromoplasts, determination of their sub-plastidic localisation; creating a data base on chromoplastic proteome; improving genome annotation and incl ...
8.2 All Genetic Information Is Encoded in the Structure of DNA
8.2 All Genetic Information Is Encoded in the Structure of DNA

Document
Document

... Cardamom mosaic virus, a possible member of the family Potyviridae has been associated with the mosaic disease (Katte disease) of small cardamom in India. A virus isolated from the symptomatic cardamom leaves was positive in ELISA only with antiserum to the Guatemalan isolate of cardamom mosaic viru ...
Document
Document

... proteins.A protein is composed of smaller molecules called amino acids, and the structure and function of the protein is determined by the sequence of its amino acids. The sequence of amino acids, in turn, is determined by the sequence of nucleotide bases in the DNA. A sequence of three nucleotide b ...
Chapters 10a and 11 PowerPoint
Chapters 10a and 11 PowerPoint

... Transcription ...
Chapter 9 Suicide Gene Therapy
Chapter 9 Suicide Gene Therapy

... 4. Tumor cell enzyme transduction and kill may induce immune responses that enhance the overall therapeutic response. 5. Prodrugs are not required to exhibit intrinsic specificity for cancer cells; they are designed to be activated by the foreign enzymes, which is technically easier to achieve. ...
The Mitochondria as a Minimal Chassis:
The Mitochondria as a Minimal Chassis:

... “To allow homologous recombination between the new construct and rho+ mtDNA, the last S. douglasii cox1 exon and part of its terminator region were cloned upstream of the cox1::RIP1m gene. This large additional region homologous to the 3′ part of the cox1 gene (886 bp) should promote integration of ...
< 1 ... 268 269 270 271 272 273 274 275 276 ... 445 >

Genome editing

Genome editing, or genome editing with engineered nucleases (GEEN) is a type of genetic engineering in which DNA is inserted, replaced, or removed from a genome using artificially engineered nucleases, or ""molecular scissors."" The nucleases create specific double-stranded break (DSBs) at desired locations in the genome, and harness the cell’s endogenous mechanisms to repair the induced break by natural processes of homologous recombination (HR) and nonhomologous end-joining (NHEJ). There are currently four families of engineered nucleases being used: Zinc finger nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), the CRISPR/Cas system, and engineered meganuclease re-engineered homing endonucleases.It is commonly practiced in genetic analysis that in order to understand the function of a gene or a protein function one interferes with it in a sequence-specific way and monitors its effects on the organism. However, in some organisms it is difficult or impossible to perform site-specific mutagenesis, and therefore more indirect methods have to be used, such as silencing the gene of interest by short RNA interference (siRNA) . Yet gene disruption by siRNA can be variable and incomplete. Genome editing with nucleases such as ZFN is different from siRNA in that the engineered nuclease is able to modify DNA-binding specificity and therefore can in principle cut any targeted position in the genome, and introduce modification of the endogenous sequences for genes that are impossible to specifically target by conventional RNAi. Furthermore, the specificity of ZFNs and TALENs are enhanced as two ZFNs are required in the recognition of their portion of the target and subsequently direct to the neighboring sequences.It was chosen by Nature Methods as the 2011 Method of the Year.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report