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unit 7 exam study guide
unit 7 exam study guide

... 13. How did Rosalind Franklin contribute to determining the structure of DNA? 14. Who won the Nobel Prize for determining the structure of the DNA. 15. What makes up the “backbone” of a DNA molecule? 16. What makes up the "rungs" of a DNA molecule? 17. What type of bonds holds the DNA bases together ...
Chapter 04
Chapter 04

... • X chromosome determines sex of offspring • Two X chromosomes in female cells, one X chromosome in male cells • All eggs get X chromosome • Half of sperm get X chromosome, other half get Y chromosome ...
11b
11b

Blueprint of Life #2
Blueprint of Life #2

... Darwin/Wallace theory of evolution by natural selection and isolation accounts for divergent and convergent evolution:  Natural selection states that those organisms that have characteristics that best suit them to their environment will survive, reproduce and pass some of those characteristics on ...
Russian Academy of Sciences, Kurchatov Sq.46,
Russian Academy of Sciences, Kurchatov Sq.46,

... Figure l. Arrangement of genetic loci in the Pgd-KIO region of the Drosophila X chromosome. The orientation is from centromere-distal (left) to centromere-proximal (right). Added or changed loci are marked by asterisks (see text). Tolchkov 1985, Dros. Inf. Servo 61 :24; Alatortsev, V.E., LA. Kramero ...
Catastrophic Epilepsy of Infancy
Catastrophic Epilepsy of Infancy

... • If the child has a genetic change (polymorphism or deleterious mutation; doesn’t matter) there are only ...
Linkage map - Cloudfront.net
Linkage map - Cloudfront.net

... DNA fingerprinting – compare unknown DNA to known DNA to find out if they match  DNA cut by restriction enzymes would show same sizes each time (same palindrome sequence)  Called restriction fragment length polymorphisms ...
Chromosomes
Chromosomes

... Mutations = Changes in one or a few nucleotides ...
1. A 6-frame translation map of a segment of DNA is shown, with
1. A 6-frame translation map of a segment of DNA is shown, with

... from G to T. Compared to the original sequence above, would the transcript from this mutant sequence likely have more or fewer associated ribosomes, and why? Mutation creates the mRNA sequence AUGUAA which would initiate translation and immediately terminate it, releasing ribosomes, so likely to hav ...
File - HCDE Secondary Science
File - HCDE Secondary Science

... The parts of a chromosome are held together by a ______________________. Only animal cells have __________________ to help with chromosome movement. During ___________________ sister chromatids are separated at the _________________ and are pulled to opposite ends of the cell. 5. DNA is ____________ ...
DNA
DNA

... The nucleotides are joined to one another by hydrogen bonds to form the rungs of a new DNA molecule. As the complementary nucleotides are fitted into place, an enzyme called DNA polymerase links them together by bonding the phosphate group of one nucleotide to the sugar molecule of the adjacent nuc ...
The Two Versions of the Human Genome - Max-Planck
The Two Versions of the Human Genome - Max-Planck

... certain mutations are distributed between the two parts of the genome? “Because, it can mean, for instance, the difference between cancer and no cancer,” she says. “If there are two mutations – for example, of the BRCA1 risk gene associated with breast cancer – they need not necessarily cause the di ...
1 Exam 2 CSS/Hort 430/530 2010 1. The concept of “one gene: one
1 Exam 2 CSS/Hort 430/530 2010 1. The concept of “one gene: one

... 5. In the case of the epistatic interaction between VRN2 and VRN1 of barley, the hypothesis is that in the absence of a period of cold treatment (vernalization) a. A repressor encoded by VRN2 binds to VRN1, thus preventing the expression of VRN1 b. The mRNA transcribed from VRN1 is degraded by VRN2 ...
Genes
Genes

... • 23 pairs of DNA molecules (46 total) are located in the nucleus of all cells except sperm and oocytes – 23 molecules are inherited from each parent • Recall that DNA is a double stranded molecule of nucleotides that are held together by hydrogen bonds between complimentary bases across the 2 stran ...
Atypical Patterns of Inheritance
Atypical Patterns of Inheritance

... • In man one form of retinitis pigmentosa, a disorder of progressive visual impairment, is caused by double heterozygosity for mutations in two unlinked genes, which both encode proteins present in photoreceptors. Individuals with only one of these mutations are not affected. ...
Supplementary Methods of Chain et al
Supplementary Methods of Chain et al

... Simulations were performed to test whether phylogenetic inertia (an ancestral bias towards more or less conservative substitutions) could account for the observed proportion of radical and conservative substitutions at each stage of duplicate gene evolution. A maximum likelihood estimate of the ance ...
Genetic Engineering
Genetic Engineering

... • Transgenic Plants – Genes can be inserted in to the plant DNA by a bacterium which infects plants. – Natural insecticides such as BT – Plants which produce their own fertilizer – Fruits and vegetables which don’t spoil as quickly. ...
Biotechnology and Recombinant DNA
Biotechnology and Recombinant DNA

... interest from its genomic source and putting it in an expression vector. Steps: 1. Obtain the gene (PCR, restriction digest) 2. Ligate it into a vector (vector = carrier piece of DNA) 3. Transform the new recombinant DNA into bacteria/cells 4. Grow up a population of transformed cells that contain t ...
Recombinant DNA Technology
Recombinant DNA Technology

... DNA fragments with complementary sticky ends can associate to form new DNA combinations. ...
DNA
DNA

... 1. Genes had to carry info from one generation to another. 2. Genes put that info to work by determining the heritable characteristics of organisms. 3. Genes had to be easily copied ...
Curriculum Calendar Biology A 2nd Trimester 2008-2009
Curriculum Calendar Biology A 2nd Trimester 2008-2009

... - Notes 14.1 “Fossils” - Wkst: Interpreting from fossils *SC.CM.LS.04- Analyze how living things have changed over geological time, using fossils and other scientific evidence ...
division of molecular genetics
division of molecular genetics

... isolated among progeny of a hybrid between indica and japonica rice plants. The leaf variegation is regarded as a recurrent somatic mutation from the recessive pale yellow allele to the dark green revertant allele. From the pyl-v line, we also obtained a stable pyl-stb (pyl-stable) line that exhibit ...
Biotechnology Pre/PostTest Key (w/citations)
Biotechnology Pre/PostTest Key (w/citations)

... Florida EOC Coach Jumpstart _____10) What piece of laboratory equipment would you use to heat and cool reactants for a PCR reaction? A. Centrifuge B. Spin column C. Thermocycler D. Water bath Florida EOC Coach Jumpstart ...
genetic analysis in inherited metabolic disorders from diagnosis to
genetic analysis in inherited metabolic disorders from diagnosis to

... “molecule of heredity”, contains all information that are indispensable for any living organism to develop, live and reproduce (see Box 1 – fig. 1). The number of genes in the human genome is estimated at 20 000-30 000 and the coding part of DNA (exome) contain about 60 000 000 base pairs, which is ...
It is essential for students to understand
It is essential for students to understand

... the mutation will not be passed to the offspring of the organism. If the mutant cell is a gamete (sex cell), the altered DNA will be transmitted to the embryo and may be passed to subsequent generations. Gamete cell mutations can result in genetic disorders. nondisjunction ...
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Mutation



In biology, a mutation is a permanent change of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements. Mutations result from damage to DNA which is not repaired or to RNA genomes (typically caused by radiation or chemical mutagens), errors in the process of replication, or from the insertion or deletion of segments of DNA by mobile genetic elements. Mutations may or may not produce discernible changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity.Mutation can result in several different types of change in sequences. Mutations in genes can either have no effect, alter the product of a gene, or prevent the gene from functioning properly or completely. Mutations can also occur in nongenic regions. One study on genetic variations between different species of Drosophila suggests that, if a mutation changes a protein produced by a gene, the result is likely to be harmful, with an estimated 70 percent of amino acid polymorphisms that have damaging effects, and the remainder being either neutral or weakly beneficial. Due to the damaging effects that mutations can have on genes, organisms have mechanisms such as DNA repair to prevent or correct mutations by reverting the mutated sequence back to its original state.
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