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Gene Technology PowerPoint
Gene Technology PowerPoint

...  Give 2 examples of how biotechnology is being used to benefit people and animals.  (Two possible answers include insulin production and agents that eliminate blood clots.)  List two things that the genes of a DNA molecule control.  (Genes control an animal’s appearance, health, growth, and repr ...
Thomas Hunt Morgan, 1933
Thomas Hunt Morgan, 1933

... FYI: 223=83,88,608 unique sperm or eggs. Times 2 = 16,777,216 unique babies from one man and one woman. ...
The Quest for Ancient DNA
The Quest for Ancient DNA

... • Scientists believe random mutations occur at a particular rate. • DNA samples from many geographical areas are studied to determine markers and differences in mtDNA or Y chromosome DNA. ...
Assignment 2
Assignment 2

... a. In which database will you be able to find how many coding sequences are in its genome? b. How many coding sequences are there? 6. Using the NCBI genome database, find the entry for the genome of Aquifex aeolicus VF5 genome (without plasmids). (10 points) a. What is the GC content of its chromoso ...
Brooker Chapter 10
Brooker Chapter 10

... Genes encoding proteins for related functions arranged in operons Intergenic regions nontranscribed DNA Single origin of replication ...
Handout 2: Glossary
Handout 2: Glossary

... nitrogenous base One of four nitrogen containing bases - adenine, thymine, guanine, and cytosine - that make up nucleotides. nucleic acid An acid compound, such as DNA or RNA, that is found in the nucleus of a cell. nucleotides A chemical subunit composed of a five-carbon sugar, bonded to a phosphat ...
Genetic Engineering
Genetic Engineering

... organism by CUTTING DNA from one organism and INSERTING FRAGMENTS into a host. • The end result is RECOMBINANT DNA, or DNA made from two or more different organisms. ...
Use the diagram to match the letter (A-C) to the correct term(1
Use the diagram to match the letter (A-C) to the correct term(1

... 8. In DNA, which of the following determines the traits of an organism? a. Amount of adenine b. Number of sugars c. Sequence of nitrogen bases d. Strength of hydrogen bonds 9. You have separated the nucleotides in a piece of DNA. You find that 22% of the bases are adenine nucleotides. What percentag ...
How are protein made in our cells?
How are protein made in our cells?

... Uracil (RNA only) ...
Genética Molecular em Medicina Transfusional
Genética Molecular em Medicina Transfusional

... cut many times at random ...
uses_lecturenotes.pdf
uses_lecturenotes.pdf

... • Presymptomatic testing for predicting adult-onset disorders such as Huntington's disease • Presymptomatic testing for estimating the risk of developing adult-onset cancers and Alzheimer's disease • Confirmational diagnosis of a symptomatic individual • Forensic/identity testing 2.) Gene therapy – ...
Therefore
Therefore

... A) Humans have ______ chromosomes, or ______ homologous pairs. 1. Homologous: Chromosomes with the _______ genes, size and shape. B) Chromosome pairs carry genes for the same _______. 1. Most organisms have ________ genes for each trait - 1 from each parent, 1 on each member of the homologous pair. ...
Ch. 8 Mutations
Ch. 8 Mutations

... contains 3.2 billion base pairs. During DNA Replication, DNA makes an error every 100,000 base pairs and repairs it to an average of one error every 10 billion base pairs. That’s an average of 0.31 base pairs each time DNA is replicated. ...
Ch. 12.1: DNA stores Information
Ch. 12.1: DNA stores Information

... Genome: Complete set of genetic material in an organism (order of bases).  Can fit into nucleus b/c of packing system. Coiled around proteins (spools): HISTONES Coiled are coiled into helical fiber to make CHROMOSOME ...
Genome Sequencing Using a Mapping Approach
Genome Sequencing Using a Mapping Approach

... Shotgun Approach 1. The shotgun approach obtains a genomic sequence by breaking the genome into overlapping fragments for cloning and sequencing. 2. A computer is then used to assemble the genomic sequence. 3. Advances that have made this approach practical for large genomes include: a. Better compu ...
Assembly, Comparison, and Annotation of Mammalian Genomes
Assembly, Comparison, and Annotation of Mammalian Genomes

... • p-values are calculated recursively for the two subtrees, for all possible values of parsimony score and ancestral bases for each subtree • data for subtrees is combines to produce p-value at root Method developed by Mathieu Blanchette and Martin Tompa ...
TruSight One Sequencing Panel Workflow
TruSight One Sequencing Panel Workflow

... panel—covering 12 Mb of genomic content, including 4,813 genes associated with known clinical phenotypes. ...
Biology 303 EXAM II 3/14/00 NAME
Biology 303 EXAM II 3/14/00 NAME

... did her father. Which of her parents underwent nondisjunction during meiosis, giving rise to the gamete responsible for the syndrome? 1. her mother 2. her father 3. both parents 4. technically speaking, there is not enough information to tell ...
Bioinformatics
Bioinformatics

... – Study of all the genes in an individual, their interactions with each other, the environment and roles in complex disease ...
gene families
gene families

... 9. Anopheles has three chromosomes, and remarkably, when they mapped where all these 1:1 fly orthologs were on the chromosome arms, it turns out that despite a lot of gene movement between arms, the basic identity of the five chromosome arms can still be recognized (unfortunately, except for the X, ...
nature v. nurture
nature v. nurture

... diseases. "This could lead to far-reaching revelations about how our environment breeds predispositions for lots of diseases, like diabetes, cancer and heart disease." Human cells have tens of thousands of genes inside them, each with its own job, such as producing energy or overseeing cell division ...
In the Human Genome
In the Human Genome

... • Unlike the human's seemingly random distribution of gene-rich areas, many other organisms' genomes are more uniform, with genes evenly spaced throughout. • Humans have on average three times as many kinds of proteins as the fly or worm because of mRNA transcript "alternative splicing" and chemical ...
Annotation Practice Activity [Based on materials from the GEP
Annotation Practice Activity [Based on materials from the GEP

... A genome is the total genetic content of an organism. In order to study a genome, DNA is isolated from a convenient tissue source, digested with a battery of restriction enzymes or physically broken into 1-2 kb DNA fragments and cloned into appropriate vectors. The total of all the cloned fragments ...
DATA QUALITY SHEET 1 kb DNA Ladder no stain
DATA QUALITY SHEET 1 kb DNA Ladder no stain

... ...
Cross-Curricular Discussion
Cross-Curricular Discussion

... 4. Would evolution still happen if there were no transposons, retrotransposons or retroviruses messing with the genome? [Yes, but it would probably be slower, relying on ordinary mutations that arise during DNA replication when cells divide or genetic recombination of chromosomes in a new generati ...
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Human genome



The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos. Humans share 50% of their DNA with bananas.The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution.Although the sequence of the human genome has been (almost) completely determined by DNA sequencing, it is not yet fully understood. Most (though probably not all) genes have been identified by a combination of high throughput experimental and bioinformatics approaches, yet much work still needs to be done to further elucidate the biological functions of their protein and RNA products. Recent results suggest that most of the vast quantities of noncoding DNA within the genome have associated biochemical activities, including regulation of gene expression, organization of chromosome architecture, and signals controlling epigenetic inheritance.There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further. Protein-coding sequences account for only a very small fraction of the genome (approximately 1.5%), and the rest is associated with non-coding RNA molecules, regulatory DNA sequences, LINEs, SINEs, introns, and sequences for which as yet no function has been elucidated.
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