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`We are all virtually identical twins`
`We are all virtually identical twins`

... One of the most exciting things we have shown is that our genetic code is our living history. Written in the three billion letters of the genetic code contained in each of our one hundred trillion cells is the recorded history of our humanity. We can trace some duplications in our chromosomes back m ...
PCR - share1
PCR - share1

... of …protein known as a "transport protein." The gene that controls increased production of the transport protein was taken from Arabidopsis, a relative of the cabbage …. The transport protein uses energy available in the cells to move salt – in the form of sodium ions -- into compartments within the ...
DNA re-arrangements - Homepages | The University of Aberdeen
DNA re-arrangements - Homepages | The University of Aberdeen

... influenzae strains with different LPS was sequenced, it was found that they also had different CAAT numbers ...
EGL Exome Coverage Tool
EGL Exome Coverage Tool

... EGL Exome Coverage Tool This tool can be used to view typical depth of sequence coverage obtained by exome sequencing performed by our laboratory. These data were calculated based on approximately 30 samples processed using our exome pipeline. An individual base is considered to have high coverage i ...
"Humies" Awards 2012 — Philadelphia, Pennsylvania
"Humies" Awards 2012 — Philadelphia, Pennsylvania

... Uday Kamath, Kenneth A De Jong, and Amarda Shehu. "An Evolutionary-based Approach for Feature Generation: Eukaryotic Promoter Recognition." IEEE Congress on Evolutionary Computation (IEEE CEC), New Orleans, LA, pg. 277-284, 2011 ...
kamath-slides - Human Competitive
kamath-slides - Human Competitive

... Uday Kamath, Kenneth A De Jong, and Amarda Shehu. "An Evolutionary-based Approach for Feature Generation: Eukaryotic Promoter Recognition." IEEE Congress on Evolutionary Computation (IEEE CEC), New Orleans, LA, pg. 277-284, 2011 ...
14.1 Human Chromosomes
14.1 Human Chromosomes

... Many human genes, including the genes for blood group, have multiple alleles. A gene located on a sex chromosome is a sex-linked gene. The genes on sex chromosomes show a sex-linked pattern of inheritance, since females have two copies of many genes (located on X chromosomes) while males have just o ...
Microbial Genetics
Microbial Genetics

... Genetic Code is Degenerative Genetic Code is Universal ...
Contemporary Biology Per
Contemporary Biology Per

... so genetically similar, crossing individuals of the same breed increases the chances of _______ alleles pairing, which can lead to an increase in genetic ________. 14. A ___________ is an inheritable change in genetic information. Though most of the time DNA replication occurs perfectly, every once ...
problem set
problem set

... Paralogous genes are derived from gene duplications and have diverged to perform different functions in a given organism. Orthologous genes typically perform the same function in different organisms, and have diverged in sequence due to mutations associated with speciation (Fig. 6.26b). The complexi ...
Genome editing
Genome editing

... CRISPR-Cas system – an form of acquired immunity found in bacteria. The guide RNA directs the Cas9 protein to a target site. Creating a guide RNA is very simple. ...
Genetics, Exam 2, Sample A  Name ___________________________
Genetics, Exam 2, Sample A Name ___________________________

... recessive male. What proportion (%) of her progeny would express each of the following phenotypes? Notched tail, white markings on dorsal fin _____________ Notched tail, no white markings on dorsal fin _____________ Smooth tail, white markings on dorsal fin _____________ Smooth tail, no white markin ...
GENETICS – BIO 300
GENETICS – BIO 300

... lack of correlation with biological complexity  C-value paradox DNA repeat sequences make up large fraction of eukaryotic genomes genome size correlates with amount of DNA derived from transposable elements e.g., ~ half of the human genome is derived from transposable elements ...
1 word is genus and
1 word is genus and

... 53. Name the two types of gametes: _sperm (X) or (Y) and egg (X) 54. Name the four types of nitrogen bases found in DNA: A= Adenine T= Thymine C= Cytosine G= Guanine 55. What is Chargoff’s rule about the nitrogen bases? A=T and C=G ...
Genetic engineering
Genetic engineering

... well as among different species. DNA sequences within most genes contain the information to direct the order of amino acids within polypeptides according to the genetic code. In the code, a three-base sequence specifies one particular amino acid among the 20 possible choices. One or more polypeptide ...
NAME CH11 In class assignment Due 2/18/14 Across 1. Initials of
NAME CH11 In class assignment Due 2/18/14 Across 1. Initials of

... 3. Separates DNA into fragments by using an electrical current through a gel- ELECTROPHORESIS 4. Circular DNA commonly inserted into bacteria to allow for multiplication- PLASMID 6. Number of loci that the FBI needs from a suspect's DNA- THIRTEEN 10. Organism that contains DNA from a different speci ...
Variations - Bioinformatics Unit
Variations - Bioinformatics Unit

Bioinformatics Research - Purdue University :: Computer Science
Bioinformatics Research - Purdue University :: Computer Science

The purines In DNA, the pyrimidine bases are
The purines In DNA, the pyrimidine bases are

... *** The purines (A and G) are the same. In DNA, the pyrimidine bases are thymine (T) and cytosine (C). In RNA, the pyrimidine bases are uracil (U) and cytosine (C). *** The phrase “CUT down the pyramids” may help you remember that cytosine, uracil, and thymine are all pyrimidines. Remember: The back ...
The Human Genome
The Human Genome

... spots. In cells in some parts of the body, one X chromosome is switched off. In other parts of the body, the other X chromosome is switched off. As a result, the cat's fur will have a mixture of orange and black spots. Male cats, which have just one X chromosome, can have spots of only one color. ...
投影片 1
投影片 1

...  Region of DNA that is associated with a particular phenotypic trait  Phenotypic characteristic varies in degree and attributes to interaction between two or more genes  QTL may not be gene itself, but as a sequence of DNA, is closely linked with the target gene ...
Study Guide for LS
Study Guide for LS

... - In a pedigree, squares represent males. - In a pedigree, circles represent females. ...
DNA NOTES
DNA NOTES

... 19. In the cytoplasm, mRNA attaches to a ________________. The ________________, with its attached mRNA, is now ready to synthesize a __________________. 20. During Translation, a __________ molecule transfers an _____________________to the ribosome. Each new ______________________links with the pre ...
PPT File
PPT File

... The Human Globin Genes • The genes encoding the various globin proteins evolved from one common ancestral globin gene, which duplicated and diverged about 450–500 ...
Bio1A Unit 2 Study Guide Cell Cycle
Bio1A Unit 2 Study Guide Cell Cycle

... binding and removing repressors or binding activators to cause them to bind their activator  binding site   Corepressors:   In prokaryotes: non‐protein, small molecules that, when added turn down gene  expression either by removing activators or causing repressor to bind  In Eukaryotes: protein tha ...
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Human genome



The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos. Humans share 50% of their DNA with bananas.The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution.Although the sequence of the human genome has been (almost) completely determined by DNA sequencing, it is not yet fully understood. Most (though probably not all) genes have been identified by a combination of high throughput experimental and bioinformatics approaches, yet much work still needs to be done to further elucidate the biological functions of their protein and RNA products. Recent results suggest that most of the vast quantities of noncoding DNA within the genome have associated biochemical activities, including regulation of gene expression, organization of chromosome architecture, and signals controlling epigenetic inheritance.There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further. Protein-coding sequences account for only a very small fraction of the genome (approximately 1.5%), and the rest is associated with non-coding RNA molecules, regulatory DNA sequences, LINEs, SINEs, introns, and sequences for which as yet no function has been elucidated.
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