Immune Thrombocytopenic Purpura
... Rituximab treatment for symptomatic chronic ITP. Pediatr blood cancer 2006;47 Monoclonal antibody against CD20+ B cells. Rapid depletion of B-cells for 6-12 months. Mechanism in ITP ???? ...
... Rituximab treatment for symptomatic chronic ITP. Pediatr blood cancer 2006;47 Monoclonal antibody against CD20+ B cells. Rapid depletion of B-cells for 6-12 months. Mechanism in ITP ???? ...
Building Better Beef The Building Blocks Behind Wagyu By: Tracy
... quality meat consistently from genetic testing,” states Nick Bell, with Silver Wind Ranch, Evart, MI. “A lot of full blood Wagyu don’t have the genes necessary to produce offspring with high marbling or low melting point fats.” The ability for Wagyu beef to meet consumer demands by providing consist ...
... quality meat consistently from genetic testing,” states Nick Bell, with Silver Wind Ranch, Evart, MI. “A lot of full blood Wagyu don’t have the genes necessary to produce offspring with high marbling or low melting point fats.” The ability for Wagyu beef to meet consumer demands by providing consist ...
genetics genetics - Cystic Fibrosis Association of New Zealand
... of treatment. This includes physiotherapy to help clear the mucus from the lungs, antibiotics to fight infection, and enzyme supplements with food to help digestion. Although new treatments are being developed, which will undoubtedly improve the quality and length of life for people with CF, the con ...
... of treatment. This includes physiotherapy to help clear the mucus from the lungs, antibiotics to fight infection, and enzyme supplements with food to help digestion. Although new treatments are being developed, which will undoubtedly improve the quality and length of life for people with CF, the con ...
Plant Genome Resources at the National Center for Biotechnology
... names or aliases, gene names or symbols, locus identifiers, gene products or descriptions, genetic marker or GenBank identifiers. Multiple search terms can be combined using Boolean logic. Since the early 1990s, various lines of research have shown that large-scale genome structure is conserved in b ...
... names or aliases, gene names or symbols, locus identifiers, gene products or descriptions, genetic marker or GenBank identifiers. Multiple search terms can be combined using Boolean logic. Since the early 1990s, various lines of research have shown that large-scale genome structure is conserved in b ...
The dystrophin / utrophin homologues in Drosophila and in sea urchin
... Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel ...
... Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel ...
Genetics of Hemophilia
... factor levels low enough to be in the mild range of deficiency. Females who carry hemophilia should have their factor (VIII or IX) levels checked to ensure they have adequate levels for normal blood clotting. See the “Hemophilia Carrier Fact Sheet” for additional information regarding women who are ...
... factor levels low enough to be in the mild range of deficiency. Females who carry hemophilia should have their factor (VIII or IX) levels checked to ensure they have adequate levels for normal blood clotting. See the “Hemophilia Carrier Fact Sheet” for additional information regarding women who are ...
Genome sequence of Aspergillus luchuensis
... Historically, A. luchuensis was isolated primarily from awamori koji in the Okinawa islands by Inui in 1901,6 who stated that A. luchuensis is the major fermentation agent in awamori production and that it possesses uniseriate conidial heads. In the same year, Usami also isolated two major kuro koji ...
... Historically, A. luchuensis was isolated primarily from awamori koji in the Okinawa islands by Inui in 1901,6 who stated that A. luchuensis is the major fermentation agent in awamori production and that it possesses uniseriate conidial heads. In the same year, Usami also isolated two major kuro koji ...
Guidance on the Use of Biochemical and Molecular Markers
... the different genes, with their respective markers, would be considered as different methods for examining the same characteristic, i.e. tolerance to Formula X. However, the different genes are likely to have a different chemical mechanism to produce the tolerance to Formula X. Thus, the chemicals p ...
... the different genes, with their respective markers, would be considered as different methods for examining the same characteristic, i.e. tolerance to Formula X. However, the different genes are likely to have a different chemical mechanism to produce the tolerance to Formula X. Thus, the chemicals p ...
... droplets within hepatocytes or incorporated into very-low-density lipoproteins (VLDL) and secreted into the blood. Once in the blood, triglyceride content of these particles is progressively reduced by the action of lipoprotein lipase (LPL), eventually resulting in intermediate-density lipoproteins ...
Centro Medico Mantia
... • injected through ultrasound directly in the spot of muscle, tendon and/or joint injury The treatment, which reported very positive results, is carried out at the Mantia Group and has no particular side effects: as a matter of fact platelets are produced by the patient’s body and the injection is ...
... • injected through ultrasound directly in the spot of muscle, tendon and/or joint injury The treatment, which reported very positive results, is carried out at the Mantia Group and has no particular side effects: as a matter of fact platelets are produced by the patient’s body and the injection is ...
Gene prediction and Genome Annotation
... Gene finding –similarity based• Not much prediction, sensu strictu • Restricted to what can be aligned • Only possible when (closely) related gene and genome sequences exist • or entirely dependent on EST (cDNA) or RNASeq • Will not ‘predict’ fast evolving genes or ‘new’ genes • No need for trainin ...
... Gene finding –similarity based• Not much prediction, sensu strictu • Restricted to what can be aligned • Only possible when (closely) related gene and genome sequences exist • or entirely dependent on EST (cDNA) or RNASeq • Will not ‘predict’ fast evolving genes or ‘new’ genes • No need for trainin ...
Promoter Analysis of the Mouse Sterol Regulatory Element
... leucine zipper family (1, 2). In contrast to other members of this family, SREBPs are synthesized as precursor proteins that remain bound to the endoplasmic reticulum and the nuclear envelope in the presence of sufficient sterol concentrations. Upon sterol deprivation, the precursor protein undergoe ...
... leucine zipper family (1, 2). In contrast to other members of this family, SREBPs are synthesized as precursor proteins that remain bound to the endoplasmic reticulum and the nuclear envelope in the presence of sufficient sterol concentrations. Upon sterol deprivation, the precursor protein undergoe ...
Early combination antibiotic therapy yields improved survival
... (21–23). To qualify as potential pathogens causing shock, isolates from anatomical sites and/or blood cultures were required to have been obtained within 48 hrs of onset of shock. A priori criteria were developed to uniformly determine the primary pathogen/ pathogens and to assess the appropriatenes ...
... (21–23). To qualify as potential pathogens causing shock, isolates from anatomical sites and/or blood cultures were required to have been obtained within 48 hrs of onset of shock. A priori criteria were developed to uniformly determine the primary pathogen/ pathogens and to assess the appropriatenes ...
genetic studies of the human complement c4 region in mhc class iii
... target is provided by antibodies, for which reason the classical pathway is relatively slow. In a secondary encounter with the microbe, when specific antibodies are present, the classical pathway activation is immediate. Human IgG1, IgG3 and IgM antibodies are the most effective in binding C1q leadi ...
... target is provided by antibodies, for which reason the classical pathway is relatively slow. In a secondary encounter with the microbe, when specific antibodies are present, the classical pathway activation is immediate. Human IgG1, IgG3 and IgM antibodies are the most effective in binding C1q leadi ...
WHAT HAS THE HUMAN GENOME EVER DONE FOR US?
... As another year in this great endocrine world draws to a close, we can start to reflect on our own year’s scientific successes and failures. I don’t know about yours, but my 2014 seems to have flown past! As the nights draw in, I find myself contemplating the important questions in life – such as wh ...
... As another year in this great endocrine world draws to a close, we can start to reflect on our own year’s scientific successes and failures. I don’t know about yours, but my 2014 seems to have flown past! As the nights draw in, I find myself contemplating the important questions in life – such as wh ...
... Virus and Human Cancer – Small and large DNA viruses, retroviruses. Induced neoplasia. Unit- 3: Methods in Cancer Cytogenetics. Chromosome preparation from bone narrow aspirates, peripheral blood and solid tumor samples. Inherited susceptibility to cancer – genetic markers of cancer predispo ...
Guideline on the Clinical Evaluation of Medicinal Products
... standardised. One of the major issues is the value of viral load measurements to assess response to antiviral therapy. Inconsistency in the definition of overall response, lack of standardisation of HBV DNA assays and heterogeneity in patients populations make comparison between different trials dif ...
... standardised. One of the major issues is the value of viral load measurements to assess response to antiviral therapy. Inconsistency in the definition of overall response, lack of standardisation of HBV DNA assays and heterogeneity in patients populations make comparison between different trials dif ...
Complete Sequence of the Mitochondrial DNA of
... is unusually variable. Complete mitochondrial gene organizations have been determined for five molluscan species (representing three different classes): the blue mussel Mytilus edulis, of the class Bivalvia (Hoffmann, Boore, and Brown 1992); the black chiton Katharina tunicata, of the class Polyplac ...
... is unusually variable. Complete mitochondrial gene organizations have been determined for five molluscan species (representing three different classes): the blue mussel Mytilus edulis, of the class Bivalvia (Hoffmann, Boore, and Brown 1992); the black chiton Katharina tunicata, of the class Polyplac ...
Dialectical Behavior Therapy Comparative Effectiveness Research Series
... how many times subjects have been the primary DBT therapist, backup therapist, pharmacotherapist, or skills leader prior to attending training. The Institute of Behavioral Research at Texas Christian University. This institute has identified five broad categories of organizational readiness for chan ...
... how many times subjects have been the primary DBT therapist, backup therapist, pharmacotherapist, or skills leader prior to attending training. The Institute of Behavioral Research at Texas Christian University. This institute has identified five broad categories of organizational readiness for chan ...
Marfan syndrome
... located. Therefore the identification of the gene defect in Marfan syndrome is a rare example ...
... located. Therefore the identification of the gene defect in Marfan syndrome is a rare example ...
- VCA Canada
... free wall and interventricular septal thickening secondary to pressure overload, dilation of the main pulmonary artery and paradoxic motion of the interventricular septum) may also be seen. Once PAH is diagnosed, further evaluation to determine the underlying etiology for development of this complic ...
... free wall and interventricular septal thickening secondary to pressure overload, dilation of the main pulmonary artery and paradoxic motion of the interventricular septum) may also be seen. Once PAH is diagnosed, further evaluation to determine the underlying etiology for development of this complic ...
Gene therapy
Gene therapy is the therapeutic delivery of nucleic acid polymers into a patient's cells as a drug to treat disease. Gene therapy could be a way to fix a genetic problem at its source. The polymers are either expressed as proteins, interfere with protein expression, or possibly correct genetic mutations.The most common form uses DNA that encodes a functional, therapeutic gene to replace a mutated gene. The polymer molecule is packaged within a ""vector"", which carries the molecule inside cells.Gene therapy was conceptualized in 1972, by authors who urged caution before commencing human gene therapy studies. By the late 1980s the technology had already been extensively used on animals, and the first genetic modification of a living human occurred on a trial basis in May 1989 , and the first gene therapy experiment approved by the US Food and Drug Administration (FDA) occurred on September 14, 1990, when Ashanti DeSilva was treated for ADA-SCID. By January 2014, some 2,000 clinical trials had been conducted or approved.Early clinical failures led to dismissals of gene therapy. Clinical successes since 2006 regained researchers' attention, although as of 2014, it was still largely an experimental technique. These include treatment of retinal disease Leber's congenital amaurosis, X-linked SCID, ADA-SCID, adrenoleukodystrophy, chronic lymphocytic leukemia (CLL), acute lymphocytic leukemia (ALL), multiple myeloma, haemophilia and Parkinson's disease. Between 2013 and April 2014, US companies invested over $600 million in the field.The first commercial gene therapy, Gendicine, was approved in China in 2003 for the treatment of certain cancers. In 2011 Neovasculgen was registered in Russia as the first-in-class gene-therapy drug for treatment of peripheral artery disease, including critical limb ischemia.In 2012 Glybera, a treatment for a rare inherited disorder, became the first treatment to be approved for clinical use in either Europe or the United States after its endorsement by the European Commission.