Multiple Domains Exist within the Upstream Activator
... and sugar derivatives called opines. The inciting strain of Agrobacterium can utilize these opines as a carbon and sometimes a nitrogen source. Agrobacterium strains can be classified based upon their ability to catabolize particular opines. (For recent reviews of the crown gall tumorigenesis proces ...
... and sugar derivatives called opines. The inciting strain of Agrobacterium can utilize these opines as a carbon and sometimes a nitrogen source. Agrobacterium strains can be classified based upon their ability to catabolize particular opines. (For recent reviews of the crown gall tumorigenesis proces ...
Solid Tumour Section Endocrine/neuroendocrine glands: Pituitary Adenomas Atlas of Genetics and Cytogenetics
... treatment of choice in most cases and can be dramatically effective, especially for microadenomas. Following surgery some patients may need radiotherapy and medical treatment with bromocriptine or somatostatin analogues to reduce prolactin secretion or inhibiting GH release from the pituitary. ACTH: ...
... treatment of choice in most cases and can be dramatically effective, especially for microadenomas. Following surgery some patients may need radiotherapy and medical treatment with bromocriptine or somatostatin analogues to reduce prolactin secretion or inhibiting GH release from the pituitary. ACTH: ...
Solid Tumour Section Liver: Intrahepatic cholangiocarcinoma Atlas of Genetics and Cytogenetics
... differences. Its incidence reveals wide geographic variations: the highest incidence is reported in Southeast Asia especially in Laos and Northeast Thailand, areas suffering from endemic infection with the liver fluke, Opisthorchis viverrini. Hepatolithiasis, another risk-factor, is also more freque ...
... differences. Its incidence reveals wide geographic variations: the highest incidence is reported in Southeast Asia especially in Laos and Northeast Thailand, areas suffering from endemic infection with the liver fluke, Opisthorchis viverrini. Hepatolithiasis, another risk-factor, is also more freque ...
Genetic defects causing mitochondrial respiratory
... to be a potentially important level of accumulation of mitochondrial mutations that can exceed the threshold for clinical consequence. In summary, where the metabolic disorder is due to a defect of a mitochondrially encoded gene, the clinical consequences of that mtDNA mutation are a function of the ...
... to be a potentially important level of accumulation of mitochondrial mutations that can exceed the threshold for clinical consequence. In summary, where the metabolic disorder is due to a defect of a mitochondrially encoded gene, the clinical consequences of that mtDNA mutation are a function of the ...
Full Text PDF - Jaypee Journals
... If the drug achieves the desired target IOP, it is continued and started in the second eye. If drug fails to reduce IOP by at least 20% IOP from baseline or produces severe side effects, we switch to another class of drugs. However, if the first drug does reduce IOP more than 20% from baseline but t ...
... If the drug achieves the desired target IOP, it is continued and started in the second eye. If drug fails to reduce IOP by at least 20% IOP from baseline or produces severe side effects, we switch to another class of drugs. However, if the first drug does reduce IOP more than 20% from baseline but t ...
A novel C. elegans zinc finger transcription factor, lsy
... onto individual agar plates and the F2 progeny were screened for lateral symmetry (lsy) defects under a stereomicroscope equipped with a fluorescent light source. Screening through 12,200 haploid genomes, we identified a total of 10 mutant alleles that display a ‘two ASER’ phenotype in which the ASE ...
... onto individual agar plates and the F2 progeny were screened for lateral symmetry (lsy) defects under a stereomicroscope equipped with a fluorescent light source. Screening through 12,200 haploid genomes, we identified a total of 10 mutant alleles that display a ‘two ASER’ phenotype in which the ASE ...
HOMEOTHERAPY Definitions and Therapeutic Schools
... Founded by Rudolf Steiner (1861-1925), Anthroposophy (Greek: anthropos = human, and sophia = wisdom) is a spiritual science based on the comprehensive view of the human being. Steiner described in great detail a method by which the scientific exploration of the transcendental, spiritual side of man ...
... Founded by Rudolf Steiner (1861-1925), Anthroposophy (Greek: anthropos = human, and sophia = wisdom) is a spiritual science based on the comprehensive view of the human being. Steiner described in great detail a method by which the scientific exploration of the transcendental, spiritual side of man ...
Heavy Chain Diversity Region Segments of the Channel Catfish
... Representative clones that met the above criteria were sequenced. The partial nucleotide sequence for three of these cirDNA clones is shown in Fig. 1. A signal joint consisting of headto-head RSS elements was present in each clone. The signal joints consisted of a conserved nonamer, a 23-bp spacer, ...
... Representative clones that met the above criteria were sequenced. The partial nucleotide sequence for three of these cirDNA clones is shown in Fig. 1. A signal joint consisting of headto-head RSS elements was present in each clone. The signal joints consisted of a conserved nonamer, a 23-bp spacer, ...
Gene Mapping, Marker-Assisted Selection, Gene Cloning, Genetic
... addressing production problems such as diseases. Previous research in the areas of traditional selective breeding and molecular genetics has resulted in genetically improved catfish (Dunham et al. 1983a, 1983b, 1987, 1990, 1992; Dunham 1996) and four releases of it to the industry. In addition to di ...
... addressing production problems such as diseases. Previous research in the areas of traditional selective breeding and molecular genetics has resulted in genetically improved catfish (Dunham et al. 1983a, 1983b, 1987, 1990, 1992; Dunham 1996) and four releases of it to the industry. In addition to di ...
ACADEMY OF MEDICINE (COLLEGE OF PAEDIATRICS) ACUTE
... the third most common cause of hospital admission, accounting for 6.6% of the total number of hospital admissions that year. [6] Sixty-four percent were mildly dehydrated, 10% moderately dehydrated and 3% severely dehydrated , while the rest were not dehydrated.[6] 45% had positive stool pathogens. ...
... the third most common cause of hospital admission, accounting for 6.6% of the total number of hospital admissions that year. [6] Sixty-four percent were mildly dehydrated, 10% moderately dehydrated and 3% severely dehydrated , while the rest were not dehydrated.[6] 45% had positive stool pathogens. ...
gene mapping, marker gene mapping, marker-assisted
... addressing production problems such as diseases. Previous research in the areas of traditional selective breeding and molecular genetics has resulted in genetically improved catfish (Dunham et al. 1983a, 1983b, 1987, 1990, 1992; Dunham 1996) and four releases of it to the industry. In addition to di ...
... addressing production problems such as diseases. Previous research in the areas of traditional selective breeding and molecular genetics has resulted in genetically improved catfish (Dunham et al. 1983a, 1983b, 1987, 1990, 1992; Dunham 1996) and four releases of it to the industry. In addition to di ...
Understanding the Scurred condition in Polled Cattle
... Most calves that are horned can be identified at birth or shortly after, and almost always by weaning time. Distinguishing between smooth-polled and scurred-polled is more difficult. Scurs, a rudimentary horn growth, are often not seen until cattle are nearly a year old or sometimes even older. Scur ...
... Most calves that are horned can be identified at birth or shortly after, and almost always by weaning time. Distinguishing between smooth-polled and scurred-polled is more difficult. Scurs, a rudimentary horn growth, are often not seen until cattle are nearly a year old or sometimes even older. Scur ...
Antimicrobial resistance in Staphylococcus spp.
... aiming at the use of antibiotics with an action spectrum directed only to etiological agents. The improper prophylactic use of antibiotics that can select resistant microorganisms also contributes to this situation, thus increasing not only risks for infection, but also its severity and difficulty o ...
... aiming at the use of antibiotics with an action spectrum directed only to etiological agents. The improper prophylactic use of antibiotics that can select resistant microorganisms also contributes to this situation, thus increasing not only risks for infection, but also its severity and difficulty o ...
How Will We Regulate Genetic Enhancement
... under a grant from the Ethical, Legal, and Social Implications Research Program, Human Genome Research Institute, National Institutes of Health (No. 1 R01 HG01446-01A1). The author thanks Tom Murray and Eric Juengst for their helpful comments on earlier drafts; John Starn, Michael Cosgrove, Jennifer ...
... under a grant from the Ethical, Legal, and Social Implications Research Program, Human Genome Research Institute, National Institutes of Health (No. 1 R01 HG01446-01A1). The author thanks Tom Murray and Eric Juengst for their helpful comments on earlier drafts; John Starn, Michael Cosgrove, Jennifer ...
Category 2000
... polymorphisms (R219K, V771M, V825I, I883M and I405V) was genotyped within these genes. Based on the genotype results, 4 monkeys were selected from the 20 and treated with niacin at an escalating dosage. Their mean lipid-lowering response following drug therapy was examined, compared to those with th ...
... polymorphisms (R219K, V771M, V825I, I883M and I405V) was genotyped within these genes. Based on the genotype results, 4 monkeys were selected from the 20 and treated with niacin at an escalating dosage. Their mean lipid-lowering response following drug therapy was examined, compared to those with th ...
(TNF) in sarcoidosis - Sarcoidosis, Vasculitis and Diffuse Lung
... centers around whether to prescribe corticosteroids (1). In general the decision to treat or not is guided by the presence of functional impairment particularly pulmonary or cardiac involvement, neurosarcoidosis, or hypercalcemia (18). In contrast to many other disorders, the presence of active infl ...
... centers around whether to prescribe corticosteroids (1). In general the decision to treat or not is guided by the presence of functional impairment particularly pulmonary or cardiac involvement, neurosarcoidosis, or hypercalcemia (18). In contrast to many other disorders, the presence of active infl ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008, p-ISSN:2319-7676.
... virus months or years later. Primary infection with HCMV is usually not diagnosed, because it is asymptomatic or associated with a mild influenza like illness in the normal host. Symptomatic primary HCMV may occur in surgical patients who acquire the virus from blood transfusion and it is one of the ...
... virus months or years later. Primary infection with HCMV is usually not diagnosed, because it is asymptomatic or associated with a mild influenza like illness in the normal host. Symptomatic primary HCMV may occur in surgical patients who acquire the virus from blood transfusion and it is one of the ...
A Guide For Patients, Survivors, And Loved Ones
... disease is called SLL. If the cancer cells are found in the bloodstream and bone marrow, the disease is called CLL, although the lymph nodes and spleen are often also involved. Approximately 16,000 new cases of CLL and 5,000 new cases of SLL are diagnosed annually. CLL/SLL are usually diagnosed in a ...
... disease is called SLL. If the cancer cells are found in the bloodstream and bone marrow, the disease is called CLL, although the lymph nodes and spleen are often also involved. Approximately 16,000 new cases of CLL and 5,000 new cases of SLL are diagnosed annually. CLL/SLL are usually diagnosed in a ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
... In addition, several studies have been conducted to compare the effectiveness of small molecules glycoprotein IIb/IIIa inhibitors (smGPIs) such as tirofiban and eptifibatide with abciximab. The smGPIs have different specificity and binding characteristic from abciximab. [48] Data in a meta-analysis ...
... In addition, several studies have been conducted to compare the effectiveness of small molecules glycoprotein IIb/IIIa inhibitors (smGPIs) such as tirofiban and eptifibatide with abciximab. The smGPIs have different specificity and binding characteristic from abciximab. [48] Data in a meta-analysis ...
Danish Multiple Sclerosis Center Annual Report 2013
... and comfort for our patients and better working conditions for the personnel. Two new treatments for relapsing-remitting multiple sclerosis were ...
... and comfort for our patients and better working conditions for the personnel. Two new treatments for relapsing-remitting multiple sclerosis were ...
Gene therapy
Gene therapy is the therapeutic delivery of nucleic acid polymers into a patient's cells as a drug to treat disease. Gene therapy could be a way to fix a genetic problem at its source. The polymers are either expressed as proteins, interfere with protein expression, or possibly correct genetic mutations.The most common form uses DNA that encodes a functional, therapeutic gene to replace a mutated gene. The polymer molecule is packaged within a ""vector"", which carries the molecule inside cells.Gene therapy was conceptualized in 1972, by authors who urged caution before commencing human gene therapy studies. By the late 1980s the technology had already been extensively used on animals, and the first genetic modification of a living human occurred on a trial basis in May 1989 , and the first gene therapy experiment approved by the US Food and Drug Administration (FDA) occurred on September 14, 1990, when Ashanti DeSilva was treated for ADA-SCID. By January 2014, some 2,000 clinical trials had been conducted or approved.Early clinical failures led to dismissals of gene therapy. Clinical successes since 2006 regained researchers' attention, although as of 2014, it was still largely an experimental technique. These include treatment of retinal disease Leber's congenital amaurosis, X-linked SCID, ADA-SCID, adrenoleukodystrophy, chronic lymphocytic leukemia (CLL), acute lymphocytic leukemia (ALL), multiple myeloma, haemophilia and Parkinson's disease. Between 2013 and April 2014, US companies invested over $600 million in the field.The first commercial gene therapy, Gendicine, was approved in China in 2003 for the treatment of certain cancers. In 2011 Neovasculgen was registered in Russia as the first-in-class gene-therapy drug for treatment of peripheral artery disease, including critical limb ischemia.In 2012 Glybera, a treatment for a rare inherited disorder, became the first treatment to be approved for clinical use in either Europe or the United States after its endorsement by the European Commission.