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L1 Protein composition-amino acids - e
L1 Protein composition-amino acids - e

... properties: rotate plane-polarized light. The equal amounts of left- and right-handed enantiomers of AA is called racemate or racemic mixture. It does not have any optical properties. All protein molecules are composed of the L-forms of AA. D-forms of the AA have been found in small peptides in some ...
CHARMM
CHARMM

... Study conformational rearrangements in other proteins • Conformational rearrangements are at the core of key biochemical processes such as regulation of enzymatic and genetic activity. • Understanding of such processes is pharmaceutically relevant. • Such processes usually occur on timescales of s ...
Carbohydrate
Carbohydrate

... • Organic chemistry is the study of Carbon compounds. • Organic compounds are compounds composed primarily of a Carbon skeleton. • All living things are composed of organic compounds. ...
Spnr, a Murine RNA-binding Protein That Is Localized to
Spnr, a Murine RNA-binding Protein That Is Localized to

... A eDNA probe containing a 3-kb insert corresponding to the Spnrgene was labeled with biotin-ll-dUTP by nick translation (GIBCO BRL, Gaithersburg, MD). The size of the product was determined to be between 200 and 400 bp. Metaphase chromosome preparations from lymphocytes of a male C57BL/6J mouse and ...
Synthetic-lethal Interactions Identify Two Novel Genes, SLA/and
Synthetic-lethal Interactions Identify Two Novel Genes, SLA/and

... in a large and diverse group of proteins that appear to interact with the cortical cytoskeleton (Koch et al., 1991). BEM1, a gene required for morphogenesis in S. cerevisiae, contains two SH3 domains (Chenevert et al., 1992), providing an indication that this sequence element might be involved in ce ...
Fatty acid
Fatty acid

The G protein pathway in neuroscience
The G protein pathway in neuroscience

... phosphatidyl inositol 4,5 bisphosphate = PI(4,5)P2 ...
G - Caltech
G - Caltech

... 4,5 bisphosphate = PI(4,5)P2 ...
PDF File
PDF File

... complex formation by these three subunit proteins has been suggested for many efflux pump assemblies in Gram-negative bacteria (13, 15–17). In fact, the functional coupling of the RND protein and the membrane fusion protein was recently demonstrated by the subunit exchange experiments using three ef ...
Conformational flexibility may explain multiple cellular roles of PEST
Conformational flexibility may explain multiple cellular roles of PEST

... surface exposed, enriched in characterized disordered protein database, and contribute largely to eukaryotic protein disorder.15 These observations motivated us to do a comprehensive conformational flexibility analysis of these motifs that might provide insight and possible explanation for their mult ...
Multiple Choice
Multiple Choice

... C. A high surface area to volume ratio was thought to be essential for nutrient diffusion throughout prokaryotic cells. ...
1 Determinants of protein-protein interfaces
1 Determinants of protein-protein interfaces

Determination of Molecular Weight of
Determination of Molecular Weight of

The Structure of Proteins
The Structure of Proteins

... 40.2 kcal./mole. The average of several calcula- structure relative to the polypeptide chain structions of this type, 36 kcal./mole, differs from the ture. (1) The hydrogen bonds between hydroxyl experimental value of the heat of formation of di- groups in the cyclol structure would have nearly keto ...
Milk Protein - AgroMedia International Inc
Milk Protein - AgroMedia International Inc

... milk production with fat supplements should be weighed against the adverse effects on milk protein. Greater than 5% fat of the total ration dry matter can cause milk protein depression. The exact mechanism for milk protein depression that fat supplements cause is not fully understood. In some studie ...
Which macromolecule stores genetic information? A. proteins B
Which macromolecule stores genetic information? A. proteins B

glance into proteins present in periodontal tissues
glance into proteins present in periodontal tissues

... that built the periodontium and the associated structures are complex entities that show distinctive functional and developmental characteristics.2 The periodontal tissues are made up numerous molecules, cells and tissues embedded in different layers of matrix structure.3 Periodontal proteins are in ...
The spe-42 gene is required for sperm–egg interactions during C
The spe-42 gene is required for sperm–egg interactions during C

... member Izumo on the sperm (Inoue et al., 2005) have been shown to disrupt sperm –egg fusion in mice with targeted deletions in these loci. The unusual reproductive biology of C. elegans makes it an excellent model system for the study of sperm – egg interactions during fertilization. The primary rep ...
05_lecture_presentation
05_lecture_presentation

... strand can bond with OH groups on other strands • Parallel cellulose molecules held together this way are grouped into microfibrils, which form strong building materials for plants ...
Molecular Plant Microbe Interactions
Molecular Plant Microbe Interactions

... EmrB from E. coli (28.2% I, 53.2% S) (accession no. 27304), EmrB from H. influenzae (26.3% I, 53.8% S) (accession no. P44927), and EmrY from E. coli (25.5% I, 53.4% S) (accession no. 52600). These proteins exhibited the greatest degree of sequence similarity in their N-terminal regions. This featur ...
lecturenotes.pdf
lecturenotes.pdf

... These regions are distributed throughout the protein and ensure that the protein is correctly folded, processed, and trafficked. • Also note that there are mutations leading to stop codons throughout the protein. These mutations result in a truncated protein being produced. Only amino acids prior to ...
Molecular and General Genetics
Molecular and General Genetics

... appeared to be very similar. In the predicted primary structures of the proteins, approximately 60% of their amino acid residues are identical (Mizuno et al. 1983 a; Overbeeke et al. 1983). We are interested in the following questions: (i) how porins are embedded in the membrane, (ii) how these prot ...
Artificial Insemination In Swine
Artificial Insemination In Swine

... 1. Essential amino acids – these amino acids are essential to the animal and must be supplied in the diet because the animal body can’t synthesize them or do so at a fast enough rate to meet its requirement. 2. Non-essential amino acids – those amino acids which are essential to the animal but are n ...
INPS: predicting the impact of non-synonymous variations on protein
INPS: predicting the impact of non-synonymous variations on protein

... residue substitution, (ii) predict whether a residue substitution promotes a DDG increase or decrease (two class predictors) and (iii) predict whether a mutation is stabilizing, destabilizing or not affecting the protein stability (three class predictors). Noticeably, it is also very difficult to fi ...
Protein Synthesis - Workforce Solutions
Protein Synthesis - Workforce Solutions

... • Newly synthesized polypeptides are frequently modified before they reach their final form where they exhibit biological activity – N-formylmethionine in prokaryotes is cleaved – leader sequences are removed by specific proteases of the endoplasmic reticulum; the Golgi apparatus then directs the fi ...
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Interactome



In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.
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