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BCL-2 Family Proteins: Critical Checkpoints of Apoptotic
BCL-2 Family Proteins: Critical Checkpoints of Apoptotic

... 2. Activation of BAX AND BAK during apoptosis 3. Unlike BAX, BAK monomers are integrated into the MOM 4. Mitochondrial intramembranous homo-oligomerization of BAX & BAK is a prime candidate mechanism of MOMP and release of cytochrome c 5. Antiapoptotic BCL-2 and BCL-XL block channel formation by BAX ...
Cloning, Characterization, and Chromosomal Mapping of Human
Cloning, Characterization, and Chromosomal Mapping of Human

... rabbit, and mouse kidneys. Considering these species differences, it is critically important to know if a protein that is homologous to rAQP-CD is present in human kidney collecting duct. Congenital nephrogenic diabetes insipidus (NDI) is a rare inherited disorder characterized by renal unresponsive ...
The arbuscular mycorrhizal fungal protein glomalin is
The arbuscular mycorrhizal fungal protein glomalin is

... Upadhyaya, 1996); also, the potential complexity associated with the protein-material extracted from soil may explain why attempts to define glomalin biochemically thus far have been foiled. As the glomalin protein has not been identified, the next logical steps of applying molecular biological tool ...
Structure and function of proteins controlling strain
Structure and function of proteins controlling strain

... at the complex Pto locus and yeast two-hybrid analysis of the chimeric genes have identified a small region of Pto involved in the interaction with AvrPto and thus also involved in the determination of specificity towards races of P. syringae carrying the avrPto gene [9,10]. In the second system, al ...
Atomic contacts in protein structures. A detailed analysis of atomic
Atomic contacts in protein structures. A detailed analysis of atomic

Releasable conjugation of polymers to proteins
Releasable conjugation of polymers to proteins

... mPEG was added drop-wise to papain during the conjugation step, the recovered product did not contain any detectable conjugate. The authors rationalize this to dimerization of papain caused by nucleophilic attack of the thiol on papain on the papain–mPEG bio-conjugate. This observation supports evid ...
Structural bioinformatics Amino acids – the building blocks of proteins
Structural bioinformatics Amino acids – the building blocks of proteins

... • Proteins are often found in water and both protein-protein and protein-water interactions must be taken into account (i.e. interactions in folded vs. denatured state) • Dominant forces responsible for tertiary structure are (believed to be) the hydrophobic interaction forces • Residues with hydrop ...
Chapter 5 Proteins - Liberty Public Schools
Chapter 5 Proteins - Liberty Public Schools

... 5 Groups of Amino Acids (Fig. 3.15) 5. Special-function- amino acids that are only used for very specific functions; methionine begins protein synthesis, proline causes kinks in the protein polymer, cysteine links chains together. ...
From: Methods in Molecular Biology, vol. 408
From: Methods in Molecular Biology, vol. 408

... Bcl-2 homology domain-containing family of proteins (87), transcriptional corepressor CtBP (88), notch-signaling pathway proteins (89,90), and many others. 2. Utilizing bioinformatics tools based on ID phenomenon one might find potential protein–protein and protein–nucleic acid interaction sites (mo ...
Current Microbiology 40:
Current Microbiology 40:

... enhancement of phosphate diffusion [1], inorganic phosphates in the soil may become more available for uptake by the roots of plants. The solubilization of organic phosphate is carried out by bacteria with the help of phosphatase enzymes, especially acid phosphatases, which play the major role in or ...
The Structure and Function of Large Biological Molecules
The Structure and Function of Large Biological Molecules

... 0.5 µm © 2011 Pearson Education, Inc. ...
Translation: DNA to mRNA to Protein
Translation: DNA to mRNA to Protein

... The genes in DNA encode protein molecules, which are the "workhorses" of the cell, carrying out all the functions necessary for life. For example, enzymes, including those that metabolize nutrients and synthesize new cellular constituents, as well as DNA polymerases and other enzymes that make copie ...
No Slide Title
No Slide Title

... MRS MRS is mainly used for (but not restricted to) protein/nucleic acid and related databases • DNA and protein sequences • Sequence related information (e.g. alignments, protein, domains, enzymes, metabolic pathways, structural information) • Hereditary information ...
Differences in Total Mitochondrial Proteins and
Differences in Total Mitochondrial Proteins and

... reduction of a polypeptide with an approximate molecular out in the presence of cycloheximide, an inhibitor of cytoweight of 36,000 in tumor mitochondria (dashed arrow). Other differences can be detected between tumor and host plasmic but not mitochondrial protein synthesis (11). There fore cytoplas ...
Protein Folding and The Impact of Mutations
Protein Folding and The Impact of Mutations

novel 4E-interacting protein in Leishmania is involved in stage
novel 4E-interacting protein in Leishmania is involved in stage

... showed that they are highly diverged from their counterparts in higher eukaryotes. Indeed, none of the LeishIF4E paralogs could complement a yeast mutant that fails to express its own eIF4E (15). We further identified the parasite eIF4G homolog, LeishIF4G-3, as the scaffold protein of the LeishIF4F c ...
Protein Phosphorylation in Rhodomicrobium vmnielii
Protein Phosphorylation in Rhodomicrobium vmnielii

... From the pattern of phosphopolypeptides from a continuously labelled culture, it is clear that at least 25 distinct phosphorylated species were present, with particularly abundant species of M , 88000,66000,55000 and 12700 (Fig. 1). The profile was unaffected by the stage of growth of the culture. T ...
Folie 1 - uni
Folie 1 - uni

... Ulf Schmitz, Introduction to genomics and proteomics II ...
Judge, P.J. and Watts, A.
Judge, P.J. and Watts, A.

... C,13C spectra recorded under weak coupling conditions shown here (left). Differential residues mobility (right) is described, with mobile residues in red, and rigid protein segments in blue — some residues are not labelled in the U[13C, 15N\(V,L,F,Y)] NpSRII sample (dark gray), and some cannot be as ...
determination of molecular weight
determination of molecular weight

... content is known, and again good agreement between experimental and calculated values has been shown for glycoproteins (8). Obviously, if the carbohydrate content is unknown, it is difficult to make estimates for partial specific volume for a glycoprotein. However, the types of carbohydrate structur ...
Lab Stn #1  Unit 5 DNA to Protein 
Lab Stn #1 Unit 5 DNA to Protein 

... In transcription, DNA bases are paired with complementary RNA bases according to the base-pairing rules: C-G and A-U. The enzyme RNA polymerase catalyzes this reaction using ATP. The number of DNA base-pairs is determined by the number of amino acids in the resulting polypeptide. The length of DNA c ...
Chapter 20. Proteins
Chapter 20. Proteins

... whole human body contains about 100,000 different proteins. Proteins are the backbone of enzymes, certain hormones, an some blood components and tissues. Proteins are the most abundant substances in nearly all cells accounting for about 15% of a cell's overall mass. Proteins contain the elements car ...
Protein Requirements of Pregnant and Lactating Women
Protein Requirements of Pregnant and Lactating Women

... curves in that report showed that for countries such as India, during pregnancy – something that might be obscured by the the GWG was between 8 and 10 kg at term, for birth weights weight gain due to the fetus as well as to fluid gain and fat acranging from < 2500 to > 3000 g, in women whose mean he ...
Slide 1
Slide 1

... protein relative to an animal’s requirement for each of the essential amino acids – A “high quality protein” called an “ideal protein” has the essential amino acids present in proportions equal to an animal’s requirements. » It says nothing about the concentration of protein in the diet – A ration w ...
From DNA to Protein: Transcription and Translation
From DNA to Protein: Transcription and Translation

... Every 3 nucleotides in a mRNA strand that encodes one amino acid in the protein is called a codon. ...
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Interactome



In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.
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