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Genetic analysis of a Chinese Han family with multiple endocrine
Genetic analysis of a Chinese Han family with multiple endocrine

... p.Cys634Tyr or p.Cys634Trp mutation, suggesting amino acid exchanges at codon 634 might have a direct impact on tumor aggressiveness in MEN2A syndrome20. A 36-yr male patient (II:7) of the studied family complied with bilateral pheochromocytoma. MEN2A represents a more aggressive form of MTC and has ...
LEEDS TEACHING HOSPITALS NHS TRUST
LEEDS TEACHING HOSPITALS NHS TRUST

... Maintain a high standard of patient focused care in accordance with Leeds Teaching Hospitals Trust guidelines and policies. Actively involve service users in providing feedback of their experience of the current service and suggestions for improvements. Appropriately define the boundaries of own pra ...
Cutaneous Manifestations of HIV Infection
Cutaneous Manifestations of HIV Infection

... diffuse, round, scaly patches of hair loss and may be koebnerization). associated with tinea on other parts of the body. ...
Paraneoplastic Syndromes and Cutaneous Signs of Malignancy
Paraneoplastic Syndromes and Cutaneous Signs of Malignancy

... – Treatment: hospitalized in single room with attention to the patient need for temperature control. Water baths with bath oils followed by application of bland ...
Curriculum for Clinical Cardiac Electrophysiology Training: Part I
Curriculum for Clinical Cardiac Electrophysiology Training: Part I

What is myotonic dystrophy? What are other names for myotonic
What is myotonic dystrophy? What are other names for myotonic

... may experience only mild stiffness or cataracts in later life. In the most severe cases, respiratory and cardiac complications can be life-threatening even at an early age. In general, the younger an individual is when symptoms first appear, the more severe symptoms are likely to be. ...
Research Manual Emergency Medicine Research Associate Program Fall 2015
Research Manual Emergency Medicine Research Associate Program Fall 2015

... method has provided an integrated measure of the balance between total oxidants and total reductants in plasma7. This project seeks to measure ORP in patients with TBI as an index of oxidative stress, and to determine if oxidative stress correlates with injury severity or clinical recovery. While di ...
Trichuris suis Therapy for Active Ulcerative Colitis
Trichuris suis Therapy for Active Ulcerative Colitis

... developing regions of the world. The reason for this difference is not explained, but the high rate of helminth colonization in less developed countries could be a protective factor (1). Helminths could be beneficial because of their unique capacity to decrease hyper-reactive immune responses (2; 3) ...
Nursing Care of Clients with Neurologic Disorders
Nursing Care of Clients with Neurologic Disorders

... and this is because it is occurring between the bone and the dura and is not actually lying on the surface of the brain itself. The points of attachment of the dura limit the extension of this haematoma anteriorly and posteriorly. You can see that there is shift of the midline. Look at the frontal h ...
Home oxygen therapy during natural disasters: lessons
Home oxygen therapy during natural disasters: lessons

... evaluated for their drug adherence because many of them lost their prescribed drugs during the tsunami. Patient medication notebooks, which are provided by the registered Japanese health insurance pharmacies [7], recorded all prescriptions and proved to be useful for identifying regular medications. ...
Hidradenitis Suppurativa and Crohn`s Disease of the Vulva
Hidradenitis Suppurativa and Crohn`s Disease of the Vulva

... histologic findings show that the connective tissue wrap around the follicular tube is weak to nonexistent at the point where the sebaceous glands attach to the follicle. This defect leads to the following sequence of events: 1. The problem starts with innate and exogenous androgens acting on the fo ...
serum copper, zinc and selenium levels in rheumatoid arthritis
serum copper, zinc and selenium levels in rheumatoid arthritis

... of RA treatment. The mode of action of sulphasalazine is not clearly known but there is evidence that it can scavenge toxic oxygen metabolites produced by neutrophils (7). Chloroquine, an anti-malarial drug, inhibits mitogen-induced lymphocyte proliferation and decreases leukocyte chemotaxis, lysoso ...
The Current Role of Hematopoietic Stem Cell Transplant
The Current Role of Hematopoietic Stem Cell Transplant

... BMT in CVID is fairly low, but it is likely to improve. I think that it will become a viable treatment for some subset of patients with CVID, likely those with ...
The Basics - The Hidradenitis Suppurativa Trust
The Basics - The Hidradenitis Suppurativa Trust

... Other diseases can cause tunnels (channels) known as sinus tracts - for example, Crohn's disease. Tests might be needed to exclude these other conditions, though they often have many other symptoms. Sometimes, if there are signs of infection, small samples (swabs) can be taken. This is to see what g ...
COPD Practical Aspects of Care, 2016
COPD Practical Aspects of Care, 2016

International AIDS Society Rapid Report
International AIDS Society Rapid Report

... sponsors, researchers and community advocates addressed these issues through formal presentations followed by group dialogue. Several times during the course of the meeting attendees broke into smaller working groups that focused specifically on issues related to trial-site countries: Botswana, Cam ...
Huygens` view of Titan
Huygens` view of Titan

... The research group placed miniscule particles of iron inside stem cells to act as cellular beacons detected by magnetic resonance imaging. With the ability to monitor where the human stem cells go in real time, researchers will have an easier time learning the best way of using the cells to treat hu ...
Biomarkers in clinical medicine
Biomarkers in clinical medicine

... Biomarkers have been used in clinical medicine for decades. With the rise of genomics and other advances in molecular biology, biomarker studies have entered a whole new era and hold promise for early diagnosis and effective treatment of many diseases. A biomarker is a characteristic that is objecti ...
kassinsec17
kassinsec17

... • People with SAD feel even worse than most people do in the winter. • Light therapy can ease ©2006 Prentice Hall ...
Neissera Meningitis - Van Buren/Cass District Health Department
Neissera Meningitis - Van Buren/Cass District Health Department

... In the event a lumbar puncture is delayed, a blood specimen should be drawn followed by the initiation of antibiotic therapy before a CT scan is performed. The administration of antibiotics prior to collecting samples may result in no culture growth. In this case, other clinical and laboratory evide ...
For resistant HTN
For resistant HTN

Okinawa Communicable Diseases Statement 2017
Okinawa Communicable Diseases Statement 2017

... Regarding Genoscholar and TB-LAMP, it was decided to carry out clinical studies at the National Reference Laboratory of the Philippines. Eiken started the clinical study in February 2017, and Nipro plans to start it in March of the same year. In 2018, a study is scheduled to start concerning the com ...
BT06 Analyze issues of public health, infectious diseases, and
BT06 Analyze issues of public health, infectious diseases, and

... Outline causes and development of cancer. A. Many different agents can cause cancer B. Cancer represents a breakdown of the processes that regulate the growth of normal cells and tissues 1. Cancer involves the uncontrolled division of body cells 2. Cell division is normally precisely regulated 3. Ce ...
The Era of Immunotherapeutics: Overcoming the challenges to fulfill
The Era of Immunotherapeutics: Overcoming the challenges to fulfill

... as foreign, mounting immune responses against them, but we have since overcome this problem by using human, humanized, or chimeric antibodies instead.(7) One issue that still needs work is developing appropriate biomarkers to predict which patients will likely respond to treatment. Trastuzumab was d ...
Decision Tree for establishing the level of data and safety monitoring
Decision Tree for establishing the level of data and safety monitoring

... to explore biological phenomena or disease processes. The total number of study participants included in Phase 1 studies varies with the drug, but is generally in the range of twenty to eighty. In Phase 1 studies, CDER can impose a clinical hold (i.e., prohibit the study from proceeding or stop a tr ...
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Multiple sclerosis research

Treatments under investigation for multiple sclerosis may improve function, curtail attacks, or limit the progression of the underlying disease. Many treatments already in clinical trials involve drugs that are used in other diseases or medications that have not been designed specifically for multiple sclerosis. There are also trials involving the combination of drugs that are already in use for multiple sclerosis. Finally, there are also many basic investigations that try to understand better the disease and in the future may help to find new treatments.
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