Public and Private Sector Contributions to the Research
... two Harvard Medical School researchers. The results of the analysis show that drug discovery and development is anything but a direct linear process. Instead it is a complex ecosystem with a wide range of novel collaboration archetypes, involving industry-academic partnerships, venture capital, dise ...
... two Harvard Medical School researchers. The results of the analysis show that drug discovery and development is anything but a direct linear process. Instead it is a complex ecosystem with a wide range of novel collaboration archetypes, involving industry-academic partnerships, venture capital, dise ...
Lymphoma
... the risk for later developing non-Hodgkin's lymphoma. At this point, it is not clear whether these drugs or the other cancers themselves increase risk. Other types of drugs, such as tumour necrosis factor (TNF) inhibitors that are used to treat autoimmune disorders, are also being studied as possibl ...
... the risk for later developing non-Hodgkin's lymphoma. At this point, it is not clear whether these drugs or the other cancers themselves increase risk. Other types of drugs, such as tumour necrosis factor (TNF) inhibitors that are used to treat autoimmune disorders, are also being studied as possibl ...
B cell characterization and reactivity analysis in multiple sclerosis
... success rates, and despite a lot of effort it is not yet known which are the targets of the autoreactive B cells and antibodies. Since MS is characterized by a heterogeneous disease course and genetic background, novel markers for the diagnosis of new patients and a multiplex treatment strategy are ...
... success rates, and despite a lot of effort it is not yet known which are the targets of the autoreactive B cells and antibodies. Since MS is characterized by a heterogeneous disease course and genetic background, novel markers for the diagnosis of new patients and a multiplex treatment strategy are ...
KIDNEY DAMAGE IN AUTOIMMUNE DISEASES
... unknown protein, called an antigen, get trapped in the filtering bed of the kidney, called the glomerulus. Once there, this antigen sets up a reaction in the normal cells that activates the so-called »killer cells«. These cells are very destructive and result in walling off the antigen. This produce ...
... unknown protein, called an antigen, get trapped in the filtering bed of the kidney, called the glomerulus. Once there, this antigen sets up a reaction in the normal cells that activates the so-called »killer cells«. These cells are very destructive and result in walling off the antigen. This produce ...
Cholesterol Treatment Coverage Criteria
... * A trial with Zetia is required unless patients are unlikely to reach goals (LDL cholesterol while taking high-intensity statins >= 130 mg/ dL). a. Therapeutic failure on standard therapy is defined as an inability to achieve and maintain an LDL cholesterol level <= 100 mg/ dL. Patients must have d ...
... * A trial with Zetia is required unless patients are unlikely to reach goals (LDL cholesterol while taking high-intensity statins >= 130 mg/ dL). a. Therapeutic failure on standard therapy is defined as an inability to achieve and maintain an LDL cholesterol level <= 100 mg/ dL. Patients must have d ...
Special Thanks - BC Pharmacy Association
... ◦ Treatment should effective, safe, and suited to the symptoms that the patient presents ◦ Treatment choice should be one that the patient is most likely to use consistently, over the long term, to achieve and maintain control of condition ...
... ◦ Treatment should effective, safe, and suited to the symptoms that the patient presents ◦ Treatment choice should be one that the patient is most likely to use consistently, over the long term, to achieve and maintain control of condition ...
Advances in the Treatment of Rare Diseases
... between having a family and risking her own life to have a baby. Despite the discouraging statistics, researchers are making progress. A 2001 case study in Chest reported that epoprostenol therapy combined with an anticoagulant can improve outcomes for mother and child when used before, during, and ...
... between having a family and risking her own life to have a baby. Despite the discouraging statistics, researchers are making progress. A 2001 case study in Chest reported that epoprostenol therapy combined with an anticoagulant can improve outcomes for mother and child when used before, during, and ...
Long-term Follow-up of Patients with Acute Myelogenous Leukemia
... • AML in CR2 with a CR1 of > 6 months duration • Exclusion: AML with t(15;17), t(8;-21), inv(16), or t(16:16)], leptomeningeal disease, candidates for allogeneic stem cell transplant within 6 months of screening, documented allergy to penicillin or beta-lactam antibiotics, active or ongoing autoimmu ...
... • AML in CR2 with a CR1 of > 6 months duration • Exclusion: AML with t(15;17), t(8;-21), inv(16), or t(16:16)], leptomeningeal disease, candidates for allogeneic stem cell transplant within 6 months of screening, documented allergy to penicillin or beta-lactam antibiotics, active or ongoing autoimmu ...
Gum Disease and Treatment Patient Card
... s Bone grafting ARTIlCIAL BONE IS USED TO REPLACE natural bone s Implant surgery PORCELAIN OR CERAMIC TEETH ARE CEMENTED ONTO METAL RODS THAT ARE INSERTED INTO YOUR JAW ...
... s Bone grafting ARTIlCIAL BONE IS USED TO REPLACE natural bone s Implant surgery PORCELAIN OR CERAMIC TEETH ARE CEMENTED ONTO METAL RODS THAT ARE INSERTED INTO YOUR JAW ...
Clinical bulletin/Bladder dysfunction in multiple sclerosis
... u Dysuria: burning sensation during urination u Abdominal or lower back pain u Fever u Increased spasticity u Dark, foul-smelling urine ...
... u Dysuria: burning sensation during urination u Abdominal or lower back pain u Fever u Increased spasticity u Dark, foul-smelling urine ...
The HubBLe Trial: Haemorrhoidal Artery Ligation (HAL) versus
... Although HAL requires an anaesthetic, evidence suggests a recovery similar to RBL but an effectiveness that approaches the more intensive surgical options. The substantial data concerning effectiveness includes one recent systematic review[8], three Randomised Control Trials (RCTs)[1921], one non-ra ...
... Although HAL requires an anaesthetic, evidence suggests a recovery similar to RBL but an effectiveness that approaches the more intensive surgical options. The substantial data concerning effectiveness includes one recent systematic review[8], three Randomised Control Trials (RCTs)[1921], one non-ra ...
PowerPoint - Hemolysis
... Use only as a last resort – can be effective when unresponsive to medications, or side effects are unacceptable Efficacy may be temporary • Relapse is possible May result in death if there is an underlying undiagnosed infections • Babesia spp. Permanent and irreversible immunosuppression results • M ...
... Use only as a last resort – can be effective when unresponsive to medications, or side effects are unacceptable Efficacy may be temporary • Relapse is possible May result in death if there is an underlying undiagnosed infections • Babesia spp. Permanent and irreversible immunosuppression results • M ...
IV Cannulation of Patients with Fractured Neck of
... Compromised flow of IV fluids Increased risk of neurovascular injury Preservation of ACF in case of ...
... Compromised flow of IV fluids Increased risk of neurovascular injury Preservation of ACF in case of ...
Feedback dose alteration significantly affects probability of pathogen eradication in nosocomial pneumonia
... that correlate with the efficacy of aminoglycosides and fluoroquinolones [6, 7, 16, 17]. In this study, we have employed the idea of knowledge of the PD-linked variable and a target value for this variable to test the hypothesis that outcome could be improved by identifying patients early in their i ...
... that correlate with the efficacy of aminoglycosides and fluoroquinolones [6, 7, 16, 17]. In this study, we have employed the idea of knowledge of the PD-linked variable and a target value for this variable to test the hypothesis that outcome could be improved by identifying patients early in their i ...
The right prevention and treatment Strategic Research Agenda for
... treatment arm. The drive towards precision medicine is taking this concept even further. It has driven the need for the development of new patient focussed clinical outcome measures; new clinical trial paradigms to support the evaluation of benefit/risk in small numbers of stratified patient populat ...
... treatment arm. The drive towards precision medicine is taking this concept even further. It has driven the need for the development of new patient focussed clinical outcome measures; new clinical trial paradigms to support the evaluation of benefit/risk in small numbers of stratified patient populat ...
Protect
... Protect enhances your innate immune system. Protect contains a specialized and standardized form of 1,3/1,6 beta-glucans known as Wellmune®. This is an important nutrient that can only be obtained in very few foods, or in supplements. Wellmune® is a natural ingredient extracted from Baker’s yeast. P ...
... Protect enhances your innate immune system. Protect contains a specialized and standardized form of 1,3/1,6 beta-glucans known as Wellmune®. This is an important nutrient that can only be obtained in very few foods, or in supplements. Wellmune® is a natural ingredient extracted from Baker’s yeast. P ...
PhenX Measures for Sickle Cell Disease (SCD) Research Project
... related to Neurology, Quality of Life, and Health Services proposed for the PhenX Toolkit below. We welcome your feedback on this important initiative. The PhenX (consensus measures for Phenotypes and eXposures) Toolkit (www.phenxtoolkit.org) provides investigators with access to well-established, l ...
... related to Neurology, Quality of Life, and Health Services proposed for the PhenX Toolkit below. We welcome your feedback on this important initiative. The PhenX (consensus measures for Phenotypes and eXposures) Toolkit (www.phenxtoolkit.org) provides investigators with access to well-established, l ...
MiSeqDx Cystic Fibrosis 139-Variant Assay Physician Insert
... inheriting a defective copy of the cystic fibrosis transmembrane conductance receptor (CFTR) gene from each parent that contains genetic mutations1,2. Typically CF individuals are diagnosed through newborn screening programs and confirmed with sweat chloride testing by the age of two3. To date, over ...
... inheriting a defective copy of the cystic fibrosis transmembrane conductance receptor (CFTR) gene from each parent that contains genetic mutations1,2. Typically CF individuals are diagnosed through newborn screening programs and confirmed with sweat chloride testing by the age of two3. To date, over ...
III
... This group of rare diseases are acute disorders of mucous membranes and skin. In 1993 a group of medical experts proposed a consensus definition and classification of EM, SJS, and TEN based on a photographic atlas and extent of body surface area involvement. According to this classification, Stevens ...
... This group of rare diseases are acute disorders of mucous membranes and skin. In 1993 a group of medical experts proposed a consensus definition and classification of EM, SJS, and TEN based on a photographic atlas and extent of body surface area involvement. According to this classification, Stevens ...
Borrelia burgdorferi sp. nov.: Etiologic Agent of Lyme Disease
... with Lyme disease and the further demonstration of immunological reactivity of patient sera with the spirochetes (12). In 1983, similar spirochetes were isolated by the Burgdorfer group from I . ricinus ticks collected in Switzerland (2). In the absence of taxonomic studies, the spirochetes which ha ...
... with Lyme disease and the further demonstration of immunological reactivity of patient sera with the spirochetes (12). In 1983, similar spirochetes were isolated by the Burgdorfer group from I . ricinus ticks collected in Switzerland (2). In the absence of taxonomic studies, the spirochetes which ha ...
Magnetic Resonance Insights Efficacy and Safety of Gadobutrol (1.0
... tissue, and ‘SD background’ is the standard deviation of the background noise. If two or more enhanced lesions were present, or in case of inhomogeneous enhancement, the investigator selected the lesion (or a part of the lesion) with maximum enhancement for measurements. The periphery of lesions was ...
... tissue, and ‘SD background’ is the standard deviation of the background noise. If two or more enhanced lesions were present, or in case of inhomogeneous enhancement, the investigator selected the lesion (or a part of the lesion) with maximum enhancement for measurements. The periphery of lesions was ...
Rheumatologic Emergencies - Calgary Emergency Medicine
... Wrist, knee, and ankle most commonly affected 2/3 will have characteristic rash (necrotic pustules on distal extremities & fingers) ...
... Wrist, knee, and ankle most commonly affected 2/3 will have characteristic rash (necrotic pustules on distal extremities & fingers) ...
