Stratified, personalised or P4 medicine: a new direction for placing
... the cause, we are effectively practicing stratified medicine. However, in recent years our understanding of both patients and their underlying conditions has significantly increased. Advances in our molecular understanding of the origins of disease have made increasingly targeted treatments possible ...
... the cause, we are effectively practicing stratified medicine. However, in recent years our understanding of both patients and their underlying conditions has significantly increased. Advances in our molecular understanding of the origins of disease have made increasingly targeted treatments possible ...
Natural Remedies for Scleroderma
... patients showed good-to-excellent improvement of their lesions. One patient had a partial relapse after 19 months, but responded well to a second course of therapy. No significant side effects were seen. The authors suggested that calcitriol be tried for at least three months in children with linear ...
... patients showed good-to-excellent improvement of their lesions. One patient had a partial relapse after 19 months, but responded well to a second course of therapy. No significant side effects were seen. The authors suggested that calcitriol be tried for at least three months in children with linear ...
chapter 30. psychotherapies 30.11 evaluation of psychotherapy
... a common domain of negative affect. Nevertheless, outcomes researchers continue to use inventories and measures as if they measure the variables indicated by their label; reliability and validity studies are clearly needed in this area. Outcome Measures Most of the outcome assessments used in contro ...
... a common domain of negative affect. Nevertheless, outcomes researchers continue to use inventories and measures as if they measure the variables indicated by their label; reliability and validity studies are clearly needed in this area. Outcome Measures Most of the outcome assessments used in contro ...
Non-immune Hemolysis_ Diagnostic Considerations
... electrophoresis of red blood cell membrane proteins are “gold standard” tests, performed in a few reference laboratories that are highly resolutive to identify each disorder and to distinguish between hereditary spherocytosis and congenital dyserythropoiesis type II. Genetic diagnosis is currently n ...
... electrophoresis of red blood cell membrane proteins are “gold standard” tests, performed in a few reference laboratories that are highly resolutive to identify each disorder and to distinguish between hereditary spherocytosis and congenital dyserythropoiesis type II. Genetic diagnosis is currently n ...
Interstitial Lung Disease Induced by Drugs and Radiation Thematic Review Series
... Recurrence with rechallenge is central to the diagnosis of druginduced ILD. This carries intrinsic risks, as pulmonary reactions of increased severity and death may ensue. Patients who demonstrate mild ILD may be rechallenged after informed consent, only if no alternate therapy drug is available to ...
... Recurrence with rechallenge is central to the diagnosis of druginduced ILD. This carries intrinsic risks, as pulmonary reactions of increased severity and death may ensue. Patients who demonstrate mild ILD may be rechallenged after informed consent, only if no alternate therapy drug is available to ...
Marilyn Bender - ConvergentEmergence
... Modern human research with psilocybin only recently began to reappear in the mid-1990s. These studies have examined or are in the process of examining psilocybin’s ability to treat: anxiety related to the diagnoses of terminal illnesses such as cancer, cluster headaches, and obsessive-compulsive dis ...
... Modern human research with psilocybin only recently began to reappear in the mid-1990s. These studies have examined or are in the process of examining psilocybin’s ability to treat: anxiety related to the diagnoses of terminal illnesses such as cancer, cluster headaches, and obsessive-compulsive dis ...
Interstitial Lung Disease Induced by Drugs and Radiation
... Recurrence with rechallenge is central to the diagnosis of druginduced ILD. This carries intrinsic risks, as pulmonary reactions of increased severity and death may ensue. Patients who demonstrate mild ILD may be rechallenged after informed consent, only if no alternate therapy drug is available to ...
... Recurrence with rechallenge is central to the diagnosis of druginduced ILD. This carries intrinsic risks, as pulmonary reactions of increased severity and death may ensue. Patients who demonstrate mild ILD may be rechallenged after informed consent, only if no alternate therapy drug is available to ...
The Multinational Association for Supportive Care in Cancer Risk
... contributive to neutropenia (granulocyte count ⬍ 500/L, including polymorphonuclear leukocytes and band forms), temperature greater than 38°C (measured orally and documented by the patient or the medical/nursing staff), and age greater than 16 years. In addition, patients’ febrile neutropenia had t ...
... contributive to neutropenia (granulocyte count ⬍ 500/L, including polymorphonuclear leukocytes and band forms), temperature greater than 38°C (measured orally and documented by the patient or the medical/nursing staff), and age greater than 16 years. In addition, patients’ febrile neutropenia had t ...
Placebos: can you get something for nothing?
... often do heal by themselves; these are often called “natural history effects”. It is also often the case that people seek treatment (and are enrolled in trials) when their (fluctuating) symptoms are at their worst; improvement in such patients is called “regression to the mean”. Before the 1970s when ...
... often do heal by themselves; these are often called “natural history effects”. It is also often the case that people seek treatment (and are enrolled in trials) when their (fluctuating) symptoms are at their worst; improvement in such patients is called “regression to the mean”. Before the 1970s when ...
Efficacy of methotrexate to prevent postoperative recurrence of Crohn’s disease
... genes may play a role in the control of intestinal immunity. For instance, NOD2/CARD15 mutations occur in a 50% of CD patients(2) and result in dysfunctional immune responses leading to chronic inflammation.(2,3) Patients with CD show also dysfunctional autophagy, defective epithelium, decreased ant ...
... genes may play a role in the control of intestinal immunity. For instance, NOD2/CARD15 mutations occur in a 50% of CD patients(2) and result in dysfunctional immune responses leading to chronic inflammation.(2,3) Patients with CD show also dysfunctional autophagy, defective epithelium, decreased ant ...
Clinical and Radiological Findings of Autosomal Dominant
... an increased bone formation rather than decreased bone resorption [14, 15]. This phenotype is not associated with an increased fracture rate and is reported to be fully penetrant [8]. Radiographs reveal sclerosis of the skull, which mainly results in increased thickness of the cranial vault; however ...
... an increased bone formation rather than decreased bone resorption [14, 15]. This phenotype is not associated with an increased fracture rate and is reported to be fully penetrant [8]. Radiographs reveal sclerosis of the skull, which mainly results in increased thickness of the cranial vault; however ...
Adverse Reactions of Enalapril
... increases nifedipine bioavailability and serum concentrations. Lower doses of nifedipine may be considered during concomitant therapy with either of these H2-antagonists. Concomitant use of nifedipine and fentanyl, especially in combination with beta- adrenergic blocking agents during surgical proc ...
... increases nifedipine bioavailability and serum concentrations. Lower doses of nifedipine may be considered during concomitant therapy with either of these H2-antagonists. Concomitant use of nifedipine and fentanyl, especially in combination with beta- adrenergic blocking agents during surgical proc ...
Calcium Pyrophosphate Dihydrate Crystal Deposition Disease (Pseudogout) of Lumbar Spine Mimicking Osteomyelitis-
... weakness improved. Fourteen months after surgery, the patient of CPPD deposition mimicking infection in the lumbar spine.5 was pain-free, and ambulatory tolerance was improved. The Parkinson’s disease, however, had become more advanced. Conclusion Although infection is the most common cause of the s ...
... weakness improved. Fourteen months after surgery, the patient of CPPD deposition mimicking infection in the lumbar spine.5 was pain-free, and ambulatory tolerance was improved. The Parkinson’s disease, however, had become more advanced. Conclusion Although infection is the most common cause of the s ...
How I manage patients with acquired haemophilia A
... patient population (Astermark et al, 2007). The EACH2 registry was a pan-European, prospective database that amassed information on 501 patients and provides the largest set of data on AHA patients to date. With respect to use of either aPCC or rFVIIa as first-line therapy for acute bleeding episode ...
... patient population (Astermark et al, 2007). The EACH2 registry was a pan-European, prospective database that amassed information on 501 patients and provides the largest set of data on AHA patients to date. With respect to use of either aPCC or rFVIIa as first-line therapy for acute bleeding episode ...
Prescribing Information
... HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use IMBRUVICA safely and effectively. See full prescribing information for IMBRUVICA. IMBRUVICA® (ibrutinib) capsules, for oral use Initial U.S. Approval: 2013 ----------------------------RECENT MAJOR ...
... HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use IMBRUVICA safely and effectively. See full prescribing information for IMBRUVICA. IMBRUVICA® (ibrutinib) capsules, for oral use Initial U.S. Approval: 2013 ----------------------------RECENT MAJOR ...
IMBRUVICA Prescribing Information
... HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use IMBRUVICA safely and effectively. See full prescribing information for IMBRUVICA. IMBRUVICA® (ibrutinib) capsules, for oral use Initial U.S. Approval: 2013 ----------------------------RECENT MAJOR ...
... HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use IMBRUVICA safely and effectively. See full prescribing information for IMBRUVICA. IMBRUVICA® (ibrutinib) capsules, for oral use Initial U.S. Approval: 2013 ----------------------------RECENT MAJOR ...
Nasal irrigation is a simple, inexpensive treatment that
... Medical management of rhinosinusitis includes antibiotics, decongestants, corticosteroids, and mucolytics.19 Therapy is usually directed at alleviating or reducing symptoms, eradicating the underlying cause, or both. Use of irrigating solutions before patients take decongestants or corticosteroids i ...
... Medical management of rhinosinusitis includes antibiotics, decongestants, corticosteroids, and mucolytics.19 Therapy is usually directed at alleviating or reducing symptoms, eradicating the underlying cause, or both. Use of irrigating solutions before patients take decongestants or corticosteroids i ...
Original articles
... serious conditions may occur with herbs17,18 . They may induce allergic and toxic reactions, some CAMs such as acupuncture may cause trauma of vital tissue 17-19 . Many patients started to use of these products by hearing from friends-relatives (137 patients) and communicating devices such as newspa ...
... serious conditions may occur with herbs17,18 . They may induce allergic and toxic reactions, some CAMs such as acupuncture may cause trauma of vital tissue 17-19 . Many patients started to use of these products by hearing from friends-relatives (137 patients) and communicating devices such as newspa ...
Prospective Randomized Trial of Docetaxel Versus Best
... considerably, and results have been reported incompletely.3 In a recent review of second-line chemotherapy for NSCLC, Fossella et al3 reported disappointing results for the treatment of this patient population. In almost half the studies, no responses were seen, and in most of the others, the overal ...
... considerably, and results have been reported incompletely.3 In a recent review of second-line chemotherapy for NSCLC, Fossella et al3 reported disappointing results for the treatment of this patient population. In almost half the studies, no responses were seen, and in most of the others, the overal ...
Case Management
... your mouth, nose and eyes – Shedding (sloughing) of your skin – If you have Stevens-Johnson syndrome, several days before the rash develops you may experience: • Fever, Sore throat, Cough, Burning eyes ...
... your mouth, nose and eyes – Shedding (sloughing) of your skin – If you have Stevens-Johnson syndrome, several days before the rash develops you may experience: • Fever, Sore throat, Cough, Burning eyes ...
O A RIGINAL RTICLES
... The present study shows that dermatophytosis was more common in the age group of 1-10 years (69 cases) followed by 31-40 years (26 cases), which is comparable with other studies done by (Hanaa, 1987; Hanan, 1998; Omar, 2000). All T. violaceum isolates were from patients aged 1-10, except three isola ...
... The present study shows that dermatophytosis was more common in the age group of 1-10 years (69 cases) followed by 31-40 years (26 cases), which is comparable with other studies done by (Hanaa, 1987; Hanan, 1998; Omar, 2000). All T. violaceum isolates were from patients aged 1-10, except three isola ...
2016 Mantle Cell Lymphoma Workshop Highlights Advances in
... them from the antitumor immune responses. Research suggests that lymphoma cells do attract regulatory T-cells and support their development through a variety of strategies. In NHL, Dr. Ansell explained, “the microenvironment has been fashioned by the tumor ...
... them from the antitumor immune responses. Research suggests that lymphoma cells do attract regulatory T-cells and support their development through a variety of strategies. In NHL, Dr. Ansell explained, “the microenvironment has been fashioned by the tumor ...
SIH
... heroin and methadone to clients who do not respond to other forms of treatment, subject to the findings, due in 2009, of pilots exploring the use of this type of treatment”. (H.M.Government Drug Strategy, 2008) ...
... heroin and methadone to clients who do not respond to other forms of treatment, subject to the findings, due in 2009, of pilots exploring the use of this type of treatment”. (H.M.Government Drug Strategy, 2008) ...
The spectrum of CMV disease in solid organ transplant recipients
... CMV viral load is an important predictor of CMV disease; the level of viremia has been directly associated with risk of CMV disease following solid organ transplant (SOT) (2). The host immune response also plays an important role; patients who are donor seropositive and recipient seronegative (D+/R− ...
... CMV viral load is an important predictor of CMV disease; the level of viremia has been directly associated with risk of CMV disease following solid organ transplant (SOT) (2). The host immune response also plays an important role; patients who are donor seropositive and recipient seronegative (D+/R− ...
Clinical Microbiology in the 21st Century
... laboratories do not take these into account when predicting the efficacy of a particular course of therapy. Point-of-care testing has undergone tremendous growth in the healthcare arena and will continue to do so in the future. However, the relatively few infectious disease diagnostic tests that can ...
... laboratories do not take these into account when predicting the efficacy of a particular course of therapy. Point-of-care testing has undergone tremendous growth in the healthcare arena and will continue to do so in the future. However, the relatively few infectious disease diagnostic tests that can ...