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Clinical Decision
Clinical Decision

... about a patient but also what data are needed to determine what is true. Even when the diagnosis is known, there often are challenging management decisions that test the physician’s knowledge and experience: Should I treat the patient or allow the process to resolve on its own? If treatment is indic ...
Orthoptics Curriculum Framework - British and Irish Orthoptic Society
Orthoptics Curriculum Framework - British and Irish Orthoptic Society

... Orthoptics and the profession as a whole. There has been no formal BIOS curriculum document since Orthoptics became a graduate profession in 1992. Since then, there has been an overall consensus about what core competencies are, but with increasing emphasis on orthoptists undertaking extended roles ...
What is the significance of the JAK2V617F mutation
What is the significance of the JAK2V617F mutation

... JAK2 V617F mutation did not explain all the cases and clinical manifestations of myelofibrosis and related MPNs.5 In addition to JAK2 V617F, a number of mechanisms (see Figure below) were identified to cause overactivation of the JAK pathway. Myelofibrosis is a complex disease characterized by multi ...
Emerging Role of CD20 Blockade in Allogeneic Hematopoietic Cell
Emerging Role of CD20 Blockade in Allogeneic Hematopoietic Cell

... such as CD20 blockade, which appear to be improving outcomes in allogeneic hematopoietic cell transplant recipients. Administration of the chimeric murine/human anti-CD20 monoclonal antibody, rituximab, prior to hematopoietic cell allografting or as part of preparative regimens appears to reduce tre ...
Laboratory evaluation of the immune system Authors
Laboratory evaluation of the immune system Authors

... There are several methods for determining serum Ig levels, and laboratories use different systems. Therefore, it is critical that age-adjusted normal reference ranges are provided. Hypogammaglobulinemia is defined as an IgG less than two standard ...
clinical feature - Contemporary Pediatrics
clinical feature - Contemporary Pediatrics

... enjoyment from practice. I have found that the 2 EMR programs I have used do not time-stamp well. And as you know, you may be in and out of a room several times (like with an asthma patient getting treatments) or if you are not open to the exam screen in EMR, it is not recording ...
Presenter: Dr
Presenter: Dr

... responding to therapy needs to be further evaluated. Common laboratory tests are as follows: ESR, Rapid Streptococcal test, serology (EBV, Toxoplasmosis, Bartonella, CMV, Syphilis, and HIV), PPD placement, urine VMA and LDH. Many of these tests are self explanatory however others can be very specifi ...
The Mucinoses
The Mucinoses

... significance is a matter of debate  Associated with many systemic disorders  Fatal outcome reported with increased frequency  Must distinguish from local variants where the skin only is involved ...
An analysis of factors contributing to poor outcomes in Cystic Fibrosis
An analysis of factors contributing to poor outcomes in Cystic Fibrosis

... Genotype also predicts prognosis in cystic fibrosis. The mutations on the CFTR gene  were  divided  into  6  classes  by  Welsh  et  al.  (1993).15  Class  I  mutations  due  to  insertions  (for  example,  stop  codons),  deletions,  splice  site  mutations  or  nonsense  mutations  lead  to  abnor ...
IG Living October-November 2009
IG Living October-November 2009

... accessing the IG product they need. This is primarily a result of the current reimbursement model. Medicare reimburses IG based on the published average sale price (ASP), which is determined by the drug pricing data submitted by manufacturers from the previous two quarters. Although the ASP rate cha ...
First detection of chikungunya infection and transmission in Brunei
First detection of chikungunya infection and transmission in Brunei

... Therefore, it is unlikely that our detection of chikungunya in Brunei Darussalam was a false positive. Taken together, all the information provides clear evidence to refute the possibility that chikungunya is yet to be confirmed in Brunei Darussalam. We were unable to identify any epidemiological ...
Annual Report 2010-2011
Annual Report 2010-2011

... Whitbourn and Prof Linda Worrall-Carter they have managed to create synergies in the research priority area of cardiovascular disease. CvRC offers a new way to explore and advance this field of research through truly multidisciplinary research. CvRC’s aim is to conduct cardiovascular research with b ...
Assumptions and Consequences of Comparative Effectiveness Analysis Using Data Mining
Assumptions and Consequences of Comparative Effectiveness Analysis Using Data Mining

... this pre-set limit, then the treatment is denied. It does not matter if the drug is effective or not. That means that there are many beneficial drugs that are simply not available to patients in Britain; fully 25% of cancer patients are denied effective chemotherapy medications. (Steinbrook 2008; Ho ...
Systemic Lupus Erythematosus - UC Irvine`s Department of Medicine
Systemic Lupus Erythematosus - UC Irvine`s Department of Medicine

...  Initial criteria proposed by the ACR in 1971, revised in 1982 and 1997  Criteria designed for research purposes  Need 4 of 11 criteria for diagnosis of SLE  Not perfect, but have over 90% sensitivity and specificity  Currently two international groups are reevaluating the criteria ...
Ideal Treatment Model for Children Diagnosed
Ideal Treatment Model for Children Diagnosed

... 1. Pharmacological Treatments Commercial medicine is today the most scientifically supported mode of ADHD ...
Parkinson`s - Innovative Educational Services
Parkinson`s - Innovative Educational Services

... help explain several of the non-motor features seen in PS, including fatigue and abnormalities of blood pressure regulation. Many brain cells of people with PD contain Lewy bodies – unusual deposits or clumps of the protein alpha-synuclein, along with other proteins. Researchers do not yet know why ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)

... biomarkers, diagnostic aids and imaging technology are not available to assist in the management of OA. There are also several areas where information is still lacking; these include: epidemiology, pathophysiology, environmental risk factors, genetic predisposition and lifestyle factors. At present, ...
Guidelines on Clinical Management of Chikungunya Fever
Guidelines on Clinical Management of Chikungunya Fever

... disability in a proportion of the affected population and can cause substantial socioeconomic impact in affected countries. The socioeconomic factors and public health inadequacies that facilitated the rapid spread of this infection continue to exist. As it is a new and emerging disease it has not r ...
Remeron - Merck.com
Remeron - Merck.com

... phases of treatment. Pooled analyses of short-term placebo-controlled trials of antidepressant drugs (SSRIs and others) showed that these drugs increase the risk of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults (ages 18–24) with major depressive disorder (MD ...
OnePath Start Form
OnePath Start Form

... determined to be neutralizing in an in vitro assay. No hypersensitivity reactions were reported for this patient. It is unknown if the presence of IgG antibodies to VPRIV is associated with a higher risk of infusion reactions. Patients with an immune response to other enzyme replacement therapies wh ...
Primary Care - American University of Beirut Medical Center
Primary Care - American University of Beirut Medical Center

... This is the second edition of the Primary Care Guidelines for Lebanon. The first edition was published in 2000 through a large collaborative effort among the Lebanese Society of Family Medicine, the Departments of Family Medicine at the American University of Beirut and Universite St. Joseph, the Mi ...
Project Overview –based Integrated Systems for Mechanism the Prediction of Drug-Induced Liver Injury
Project Overview –based Integrated Systems for Mechanism the Prediction of Drug-Induced Liver Injury

... computational models reflecting the key mechanisms of drug induced hepatotoxicity. ▫ This panel may form a major aspect of the future pre-clinical DILI screening paradigm used in industry and consequently reduce the occurrence of drugs with DILI that eventually reach regulatory assessment. ...
Tacrolimus Ointment in the Treatment of Chronic Cutaneous Graft
Tacrolimus Ointment in the Treatment of Chronic Cutaneous Graft

... A summary of our results is presented in the Table. Eighteen patients were treated with tacrolimus ointment for their refractory chronic cutaneous GVHD. Thirteen patients (72%) responded to the treatment. A response was defined as effective relief of erythema and/or pruritus. Scaling, pain, and “tig ...
Midterm Pharmacotherapy I test
Midterm Pharmacotherapy I test

... BG is a 7 years old boy who brought to the ER by his parents with severe GI symptoms, low-grade fever, non-productive cough, headache, and malaise. On taking the history of the disease the parents reported that BG was complaining since last week of GI symptoms and some signs of pharyngitis. Chest X- ...
Natural Remedies for Scleroderma
Natural Remedies for Scleroderma

... patients showed good-to-excellent improvement of their lesions. One patient had a partial relapse after 19 months, but responded well to a second course of therapy. No significant side effects were seen. The authors suggested that calcitriol be tried for at least three months in children with linear ...
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Multiple sclerosis research

Treatments under investigation for multiple sclerosis may improve function, curtail attacks, or limit the progression of the underlying disease. Many treatments already in clinical trials involve drugs that are used in other diseases or medications that have not been designed specifically for multiple sclerosis. There are also trials involving the combination of drugs that are already in use for multiple sclerosis. Finally, there are also many basic investigations that try to understand better the disease and in the future may help to find new treatments.
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