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Antibody response to DBY minor histocompatibility antigen is
Antibody response to DBY minor histocompatibility antigen is

... specificity controls. All patients and donors were previously screened for antibody to HIVp24 and were known to be negative. Western blotting experiments shown in Figure 1 were used to detect the presence of antibodies specific for these proteins. Coomassie stains of E coli–derived affinity-purified ...
Induction of IgA Circulating Immune Complexes after
Induction of IgA Circulating Immune Complexes after

... nonwheat dietary protein. Five patients with dermatitis herpetiformis and 5 normal controls were fed whole w-heat and serum was collected every 30 min. After 5 hr, a gluten-free meal was given and serum was collected hourly for 5 more hours. IgA circulating immune complexes and IgG circulating immun ...
Prospective Randomized Trial Of
Prospective Randomized Trial Of

... considerably, and results have been reported incompletely.3 In a recent review of second-line chemotherapy for NSCLC, Fossella et al3 reported disappointing results for the treatment of this patient population. In almost half the studies, no responses were seen, and in most of the others, the overal ...
News in severe clinical adverse drug reactions: Stevens
News in severe clinical adverse drug reactions: Stevens

... of skin involvement is what defines the clinical diagnosis and, hence, the prognosis of the patient33. SJS corresponds to less than 10% involvement of body surface area; TEN corresponds to more than 30% involvement; the cutaneous involvement range from 10 to 30% is known as SJS-TEN overlapping34. Th ...
SICKLE CELL DISEASE IN CHILDREN AND ADOLESCENTS
SICKLE CELL DISEASE IN CHILDREN AND ADOLESCENTS

... educational and medical interventions that significantly reduce morbidity and mortality during childhood and adolescence. Comprehensive medical care includes extensive health maintenance with appropriate prophylactic measures, parental education, psychosocial support, and periodic medical assessment ...
Mycoplasma Is An Overlooked Lyme Co
Mycoplasma Is An Overlooked Lyme Co

... minutes and provide reliable results but are very expensive. 4. The PCR test (Polymerase Chain Reaction) is considered the most reliable blood test for Mycoplasma, but will not reveal the bacteria if it’s living instead in other body fluids and tissues. PCR tests are usually species-specific, expens ...
Assessment of COPD
Assessment of COPD

... lack of education in medical schools. Many family physicians have graduated without developing a working knowledge of spirometry. 2. Many offices do not have the equipment, time, or staff requirements to adequately perform or interpret spirometry. This requires an effort to develop easy accessibilit ...
Abstract presented at 4th Canadian Therapeutics
Abstract presented at 4th Canadian Therapeutics

... significant morbidity and mortality in children. 95% of ADRs are never reported. Active surveillance may be more effective than voluntary reporting in identifying and collecting comprehensive case information for severe ADRs. Objectives:1) Establish a network of full-time clinical surveillors in eig ...
Observational Study Protocol CA209653
Observational Study Protocol CA209653

... Study Design: This is a German, nationwide, prospective, observational, multicenter study in patients diagnosed with advanced RCC with clear-cell and non-clear-cell histology, who start a new systemic therapy with nivolumab for the first time and within the market authorization approval. Patients ar ...
Dermatology Maculopapular and Plaque Dermatitises
Dermatology Maculopapular and Plaque Dermatitises

... IgE or complement mediated edema of dermis or subcutaneous tissue Etiology: antigens Pathology: Mast cell stimulated to degranulate by IgE. ...
Impaired expression of Toll-like receptor 2 in nontuberculous mycobacterial lung disease Y.J. Ryu*
Impaired expression of Toll-like receptor 2 in nontuberculous mycobacterial lung disease Y.J. Ryu*

... Since exposure to these organisms is universal and the occurrence of disease is uncommon, normal host defense mechanisms must be effective enough to prevent the infection [5]. Therefore, otherwise healthy individuals who develop NTM lung disease are likely to have ...
Early-onset dementia
Early-onset dementia

... younger people are more likely to have a rarer form of dementia. Both the diagnosis and the symptoms of the condition can have a devastating impact on patients, carers and their families. Younger people are likely to have different needs and commitments than older people. They are more likely to be ...


... tissues. This means that the immune system (which normally protects the body from infections) mistakenly attacks itself. Patients with systemic lupus erythematosus produce numerous antibodies against self-antigens in several organs, such as skin, joints and kidneys. The clinical features include fev ...
Hemorrhoidal Disease: A Comprehensive Review
Hemorrhoidal Disease: A Comprehensive Review

... the course of several weeks, the pain usually will subside after 2 or 3 days, and the mass will resolve within 7 to 10 days.14 In a prospective, randomized trial, Perrotti and associates42 demonstrated that topical application of nifedipine combined with lidocaine ointment is a safe option in the co ...


Cutaneous Kaposi sarComa – Case report
Cutaneous Kaposi sarComa – Case report

... Eastern descent. It is rare observed in North America and Northern Europe. Surgical biopsy is important in diagnosis of this neoplasm. Every patient with Kaposi sarcoma must have HIV test done. Treatment of Kaposi’s sarcoma evaluated from classic form for single lesion to experimental therapies. For ...
prince henry`s institute 2013 scientific report
prince henry`s institute 2013 scientific report

... CXCL10, a protein linked to inflammation, to suppress the body’s normal immune response, and enable tumour growth and spread. The group has identified existing drugs used to treat diabetes that may be useful to treat patients with ovarian cancer. One of the greatest challenges facing medical researc ...
Corticosteroid responsiveness and clinical characteristics in childhood difficult asthma
Corticosteroid responsiveness and clinical characteristics in childhood difficult asthma

... corticosteroid resistance is important, allowing the clinician to deploy alternative therapies; conversely, in the corticosteroid sensitive patient, the dose of therapy should be minimised to avoid unwanted side-effects. A protocol driven approach for the investigation of childhood DA helps identify ...
RTOG 0848 Protocol
RTOG 0848 Protocol

... This trial compared favorably with the outcome in similar phase III trials in patients with pancreatic adenocarcinoma. This was despite the greater proportion of patients with T3 disease, lymph node positive disease, and microscopically positive margins when compared to GITSG and EORTC trials. In RT ...
Myasthenic crisis
Myasthenic crisis

... (2) Gradual onset generalized disease (involving more than one group of striated muscles, both skeletal and bulbar) (3) Acute fulminant generalized disease with severe bulbar involvement (4) Late severe disease (usually developing 2 years or more after symptoms in category 1 or 2) (5) Muscle atrophy ...
St. Baldrick`s Foundation funds new treatments in pediatric oncology
St. Baldrick`s Foundation funds new treatments in pediatric oncology

... support the research endeavors and professional development of five pairs of female Dana-Farber senior and junior researchers. Helen Gurley Brown avidly supported professional advancement of women, and the researchers will be known as Helen Mentors and Helen Fellows, respectively. “The Helen Gurley ...
product information
product information

... risk of suicidal thoughts or behaviour in patients taking these drugs for any indication. Patients treated with any AED for any indication should be monitored for the emergence or worsening of depression, suicidal thoughts or behaviour, and/or any unusual changes in mood or behaviour. Pooled analyse ...
2,6-sialylated Fc
2,6-sialylated Fc

IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... cells.(Figure.6). The patient began amphotrecin B (AmB) at a dose of 1mg/kg/day. The patient required supplemental oxygen by face mask, but not ventilatory support. Clinical improvement was gradually seen and the patient was discharged on the 12th day of hospitalization with a six-month course of or ...
Clinical Foundations 7
Clinical Foundations 7

... +: Unlikely to be present, ++: likely to be present, +++: very likely to be present, #: the more common co-morbid conditions associated with poor prognosis in exacerbations are congestive heart failure, coronary artery disease, diabetes mellitus, renal and liver failure., ##: blood tests include cel ...
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Multiple sclerosis research

Treatments under investigation for multiple sclerosis may improve function, curtail attacks, or limit the progression of the underlying disease. Many treatments already in clinical trials involve drugs that are used in other diseases or medications that have not been designed specifically for multiple sclerosis. There are also trials involving the combination of drugs that are already in use for multiple sclerosis. Finally, there are also many basic investigations that try to understand better the disease and in the future may help to find new treatments.
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