Number 1 January/March 2015 Volume 21
... Ključne riječi: duboka venska tromboza, hemodinamika, artroplastika koljena, riziko- faktori ...
... Ključne riječi: duboka venska tromboza, hemodinamika, artroplastika koljena, riziko- faktori ...
1 INTRODUCTION TO GLOMERULAR DISEASES Goal: understand
... nephropathy. Proteomic analysis of the target antigen in human “idiopathic” membranous nephropathy showed it to be the phospholipase A2 receptor (PLA2R). It has been shown that most of the reactivity to PLA2R resides in the IgG4 subclass (NEJM ...
... nephropathy. Proteomic analysis of the target antigen in human “idiopathic” membranous nephropathy showed it to be the phospholipase A2 receptor (PLA2R). It has been shown that most of the reactivity to PLA2R resides in the IgG4 subclass (NEJM ...
CML Learining Programme
... • Nilotinib and dasatinib have been rationally designed to improve binding affinity against BCR-ABL • Each agent differs in its molecular structure, how it binds to the BCR-ABL protein, and the other TKIs that it inhibits These differences have led to different patterns of activity and patterns of a ...
... • Nilotinib and dasatinib have been rationally designed to improve binding affinity against BCR-ABL • Each agent differs in its molecular structure, how it binds to the BCR-ABL protein, and the other TKIs that it inhibits These differences have led to different patterns of activity and patterns of a ...
Pneumonia in the Very Old
... age-associated diseases. The most striking characteristic of pneumonia in the very old is its clinical presentation: falls and confusion are frequently encountered, while classic symptoms of pneumonia are often absent. Communityacquired pneumonia (CAP) and nursing-home acquired pneumonia (NHAP) have ...
... age-associated diseases. The most striking characteristic of pneumonia in the very old is its clinical presentation: falls and confusion are frequently encountered, while classic symptoms of pneumonia are often absent. Communityacquired pneumonia (CAP) and nursing-home acquired pneumonia (NHAP) have ...
Imiquimod 5% cream for the treatment of actinic keratosis
... carcinoma (SCC) that makes reliable clinical distinction between the diseases difficult to determine; an AK lesion that evolves into an invasive SCC lesion can do so without displaying any distinguishing clinical features.6,7 Because it is impossible to predict the point at which an individual AK le ...
... carcinoma (SCC) that makes reliable clinical distinction between the diseases difficult to determine; an AK lesion that evolves into an invasive SCC lesion can do so without displaying any distinguishing clinical features.6,7 Because it is impossible to predict the point at which an individual AK le ...
Transfusion Indications for Patients With Cancer
... anemia and a hemoglobin level below 7 g/dL. Transfusion with hemoglobin concentrations between 7 and 10 g/dL may be indicated when significant underlying comorbidities exist, such as cardiac disease, respiratory disease, bone marrow failure, or other hematological diseases; this is because anemia ma ...
... anemia and a hemoglobin level below 7 g/dL. Transfusion with hemoglobin concentrations between 7 and 10 g/dL may be indicated when significant underlying comorbidities exist, such as cardiac disease, respiratory disease, bone marrow failure, or other hematological diseases; this is because anemia ma ...
Inflammatory Bowel Disease Part I
... condition appears to be related to a combination of genetic and environmental factors. While conventional treatments can be effective in maintaining remission and decreasing the length of active disease periods, the treatments are not without side effects, and a significant number of people sufferin ...
... condition appears to be related to a combination of genetic and environmental factors. While conventional treatments can be effective in maintaining remission and decreasing the length of active disease periods, the treatments are not without side effects, and a significant number of people sufferin ...
Hyperthyroidism and Thyrotoxicosis
... Thyrotoxicosis can also result from a destructive process in the thyroid resulting in unregulated excess release of stored thyroid hormones without increased production [1, 2]. The thyrotoxicosis syndrome may also be due to exogenous source either iatrogenic or factitious. Hyperthyroidism is conside ...
... Thyrotoxicosis can also result from a destructive process in the thyroid resulting in unregulated excess release of stored thyroid hormones without increased production [1, 2]. The thyrotoxicosis syndrome may also be due to exogenous source either iatrogenic or factitious. Hyperthyroidism is conside ...
Full Prescribing Information including BOXED WARNING
... treatment should generally be reserved for patients who suffer from a chronic illness that 1) is known to respond to antipsychotic drugs, and 2) for whom alternative, equally effective, but potentially less harmful treatments are not available or appropriate. In patients who do require chronic treat ...
... treatment should generally be reserved for patients who suffer from a chronic illness that 1) is known to respond to antipsychotic drugs, and 2) for whom alternative, equally effective, but potentially less harmful treatments are not available or appropriate. In patients who do require chronic treat ...
Analyses and Displays Associated with Outliers or
... discontinuing a drug (e.g., return of disease symptoms, introduction of a concomitant medication, and/or discontinuation- or withdrawal-effects of the drug) or due to subsequent therapy. We assume it is important to distinguish among these. Generally, at least some TFLs that include data from follow ...
... discontinuing a drug (e.g., return of disease symptoms, introduction of a concomitant medication, and/or discontinuation- or withdrawal-effects of the drug) or due to subsequent therapy. We assume it is important to distinguish among these. Generally, at least some TFLs that include data from follow ...
Hepatitis B or Hepatitis C Virus Infection Is a Risk Factor for Severe
... Among the 23 patients with severe cytolysis, intravenous drug use was the most frequent HIV transmission route category (52%); 16 (70%) were positive for HCV antibodies and 5 (22%) were positive for HBs antigen (Table 1). The median change between M0 and M1 was 72 × 106/liter for the CD4+ cell count ...
... Among the 23 patients with severe cytolysis, intravenous drug use was the most frequent HIV transmission route category (52%); 16 (70%) were positive for HCV antibodies and 5 (22%) were positive for HBs antigen (Table 1). The median change between M0 and M1 was 72 × 106/liter for the CD4+ cell count ...
8 and Systemic Disease
... patients with scleroderma10 and may result in malabsorption and diarrhea.10,19 The frequent use of strong acid-suppressing medications may contribute to bacterial overgrowth by removing the acid barrier to colonization by oropharyngeal bacteria.20 Bacterial overgrowth may be associated with malabsor ...
... patients with scleroderma10 and may result in malabsorption and diarrhea.10,19 The frequent use of strong acid-suppressing medications may contribute to bacterial overgrowth by removing the acid barrier to colonization by oropharyngeal bacteria.20 Bacterial overgrowth may be associated with malabsor ...
Full Prescribing Information for HALDOL® Decanoate
... treatment should generally be reserved for patients who suffer from a chronic illness that 1) is known to respond to antipsychotic drugs, and 2) for whom alternative, equally effective, but potentially less harmful treatments are not available or appropriate. In patients who do require chronic treat ...
... treatment should generally be reserved for patients who suffer from a chronic illness that 1) is known to respond to antipsychotic drugs, and 2) for whom alternative, equally effective, but potentially less harmful treatments are not available or appropriate. In patients who do require chronic treat ...
Treatment options in severe fungal asthma and allergic bronchopulmonary aspergillosis Richard B. Moss
... SAFS demonstrate IgE responses to fungal products derived from in vivo germination of inhaled conidia into hyphae, as these antibodies exist as a response to fungal exoproducts, hyphal cell wall components expressed during growth phase and cytoplasmic antigens [21, 22]. Secondly, there is mounting e ...
... SAFS demonstrate IgE responses to fungal products derived from in vivo germination of inhaled conidia into hyphae, as these antibodies exist as a response to fungal exoproducts, hyphal cell wall components expressed during growth phase and cytoplasmic antigens [21, 22]. Secondly, there is mounting e ...
Incidence of neonatal chlamydial conjunctivitis and its association
... All post-treatment ocular C trachomatis investigations in NCC patients were negative. Of the 24 NCC cases, four defaulted. One of the 20 who completed the study had a positive NP PCR at post-treatment investigation, though the NP DIF and NP cell culture were negative. A complete set of post-treatmen ...
... All post-treatment ocular C trachomatis investigations in NCC patients were negative. Of the 24 NCC cases, four defaulted. One of the 20 who completed the study had a positive NP PCR at post-treatment investigation, though the NP DIF and NP cell culture were negative. A complete set of post-treatmen ...
nausea management
... Adapted from Emanuel LL, Ferris FD, von Gunten CF, Von Roenn J. EPEC-O: Education in Palliative and End-of-life Care for Oncology. © The EPEC Project,™ Chicago, IL, 2005. Open Access at www. IPCRC.net. Wood GJ, Shega JW, Lynch B, Von Roenn JH. Management of Intractable Nausea and Vomiting in Patient ...
... Adapted from Emanuel LL, Ferris FD, von Gunten CF, Von Roenn J. EPEC-O: Education in Palliative and End-of-life Care for Oncology. © The EPEC Project,™ Chicago, IL, 2005. Open Access at www. IPCRC.net. Wood GJ, Shega JW, Lynch B, Von Roenn JH. Management of Intractable Nausea and Vomiting in Patient ...
Nasal Route: A Potential Alternative for Antiparkinsonism Drug
... phenomenon can be defined to be present when an adequate dosage of levodopa does not lose for at least 4 h. However, in the late stages of the disease, the duration of the “on” response becomes shorter. In addition to the apparent tolerance that appears with a chronic intake of levodopa, interpatien ...
... phenomenon can be defined to be present when an adequate dosage of levodopa does not lose for at least 4 h. However, in the late stages of the disease, the duration of the “on” response becomes shorter. In addition to the apparent tolerance that appears with a chronic intake of levodopa, interpatien ...
Autoimmune Disease is Causing Your Hashimoto Thyroiditis And How to Stop It!
... and you do have a real problem, and yes, there is hope to feel better. My wish is that this book changes your life. Autoimmune is a process where your body is destroying its own tissue. There tends to be an unnecessary mystery around autoimmune disorders and like many named diagnoses, we are sometim ...
... and you do have a real problem, and yes, there is hope to feel better. My wish is that this book changes your life. Autoimmune is a process where your body is destroying its own tissue. There tends to be an unnecessary mystery around autoimmune disorders and like many named diagnoses, we are sometim ...
Treatment of Hepatitis B in Patients With Chronic Kidney Disease
... means that at any time there are likely to be the full spectrum of possible mutations of the virus in circulation. This provides an inherent flexibility in responding to environmental pressure. As an example, the eAg is typically present early in the course of chronic HBV infection. As the immune sy ...
... means that at any time there are likely to be the full spectrum of possible mutations of the virus in circulation. This provides an inherent flexibility in responding to environmental pressure. As an example, the eAg is typically present early in the course of chronic HBV infection. As the immune sy ...
immunosuppressive drugs after solid organ transplantation
... B and T lymphocytes lack this pathway, MMF is a more selective antiproliferative agent than azathioprine.29,30 Because of this, and because MMF is less hepatotoxic and is not associated with malignancies,26 it was expected to replace azathioprine in the immunosuppressive repertoire, especially when ...
... B and T lymphocytes lack this pathway, MMF is a more selective antiproliferative agent than azathioprine.29,30 Because of this, and because MMF is less hepatotoxic and is not associated with malignancies,26 it was expected to replace azathioprine in the immunosuppressive repertoire, especially when ...
Approach to the Patient with Ascites Differential
... however, the laxity of the abdominal wall and the severity of underlying liver disease suggest that the condition can be present for some time before it is recognized. Patients who consume ethanol only intermittently may report cyclic ascites, whereas patients with nonalcoholic disease usually have ...
... however, the laxity of the abdominal wall and the severity of underlying liver disease suggest that the condition can be present for some time before it is recognized. Patients who consume ethanol only intermittently may report cyclic ascites, whereas patients with nonalcoholic disease usually have ...
Clinical NMR Imaging of the - American Journal of Neuroradiology
... also used . Computati ons from saturation-recovery and inversionrecovery se quences of th e same slice of the brain were used to ob tain numeric val ues for T , as desc ribed for the li ve r [17]. After 73 patien ts had been examined, the slice profil e was modi fi ed produ c ing an improvement in i ...
... also used . Computati ons from saturation-recovery and inversionrecovery se quences of th e same slice of the brain were used to ob tain numeric val ues for T , as desc ribed for the li ve r [17]. After 73 patien ts had been examined, the slice profil e was modi fi ed produ c ing an improvement in i ...
as dimethyl sulfoxide - Therapeutic Goods Administration
... unresectable or metastatic melanoma with BRAF V600E or V600K mutations, as detected by an FDA-approved test [see Clinical Studies (14.1)]. Mekinist, in combination with dabrafenib, is indicated for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, ...
... unresectable or metastatic melanoma with BRAF V600E or V600K mutations, as detected by an FDA-approved test [see Clinical Studies (14.1)]. Mekinist, in combination with dabrafenib, is indicated for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, ...
Tacrolimus vs. Azathioprine in myasthenia gravis treatment. A multicenter, prospective, randomized, double
... for MG in recommended doses for the disease (3 mg/day) (23–25), which are low in comparison with those used for organ transplantation (0.075-0.30 mg/kg/day). This dose has proved to be effective and safe for treating MG in previous studies (17,26). There are several studies approaching tacrolimus se ...
... for MG in recommended doses for the disease (3 mg/day) (23–25), which are low in comparison with those used for organ transplantation (0.075-0.30 mg/kg/day). This dose has proved to be effective and safe for treating MG in previous studies (17,26). There are several studies approaching tacrolimus se ...