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Reactive Arthritis (ReA) Inflammatory Bowel Disease (IBD) Arthritis
Reactive Arthritis (ReA) Inflammatory Bowel Disease (IBD) Arthritis

... For as long as scientists have studied rheumatic disease, bacterial infections have been believed to trigger certain types of arthritis. The strongest support for this theory is seen in ReA and IBD arthritis. In ReA, bacterial infections of the intestines, genitals, and upper respiratory tract typic ...
Press Release
Press Release

... announced a collaboration that will enable Tessa and Vyriad to investigate T cell and oncolytic virus combination therapies. The combination of these two therapies is highly synergistic and has the potential to target a wide range of solid tumors with increased efficacy. Tessa and Vyriad have signed ...
Adverse Dental Effects
Adverse Dental Effects

... necessary to discontinue an agent if the oral effects are severe enough. While adverse effects to medications can affect anyone, it is important to recognize that elderly patients, or those with nutritional deficiencies, may be at increased risk for developing iatrogenic oral problems. Patients olde ...
DUSC Outcome Statement - June 2015
DUSC Outcome Statement - June 2015

... anticipated, but remains within the upper bound of the range considered by the PBAC. It may be that there is some use of icatibant for less severe attacks but this cannot be ascertained from the PBS prescription data. DUSC noted that the algorithm for treatment is changing and that this may impact ...
Eradication of urinary tract infection following spinal cord
Eradication of urinary tract infection following spinal cord

... were used to identify UTI and determine when antimicrobial chemotherapy was to be administered . In addition to the monthly nurse visits which included physical exam­ ination and questioning regarding the status of the urinary tract, patients were called by telephone weekly . They were questioned sp ...
Embolization of a Chronic Left Ventricular Thrombus
Embolization of a Chronic Left Ventricular Thrombus

... to emboli from a cardiac origin. The case patient developed neurologic symptoms consistent with a left hemispheric stroke believed to be secondary to an embolic source originating in the LV. Cerebral embolism of cardiac origin is a common cause of stroke, accounting for nearly one third of all cereb ...
Professional Practice Guidelines Science, Politics, and Values: The
Professional Practice Guidelines Science, Politics, and Values: The

... label applied by advocates to a variety of nonspecific symptoms for which frequently no evidence suggests the etiologic agent of Lyme disease is responsible. The IDSA was forced to settle the claim to avoid exorbitant litigation costs, even though the society’s guidelines were based on sound science ...
2 MB - epilepsy - anaesthetic concerns
2 MB - epilepsy - anaesthetic concerns

... documented to cause extrapyramidal effects and dystonic reactions- beware ...
Increased risk of adverse events when changing
Increased risk of adverse events when changing

... needed for his serum sickness reaction. It should be noted that serum sickness may further impair lymphocyte function [13]. Several IVIG preparations are available in the United States and Europe [8,14]. Patients established on one preparation may be changed to another for either economic reasons or ...
1 FULL PRESCRIBING INFORMATION: CONTENTS*
1 FULL PRESCRIBING INFORMATION: CONTENTS*

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Anti-amoebic Treatment for Rheumatoid Disease
Anti-amoebic Treatment for Rheumatoid Disease

... his right hip joint, but the pain and disability had gotten worse. All the usual treatments had failed to alleviate his pain or slow the progress of his disease. In early 1976, Dr. Blount read an article in Modern Medicine entitled “Has One man Found the Cause and Cure of Rheumatoid Disease.” Accord ...
Atypical facial pain - University of Palestine
Atypical facial pain - University of Palestine

... predominantly women after the fourth decade of life. In primary Sjögren’s syndrome, the disease is limited to the eyes and salivary glands. With secondary Sjögren’s syndrome, patients also have an autoimmune or connective tissue disease .It is estimated that 15 percent of patients with rheumatoid ar ...
Fumaric acid esters - British Association of Dermatologists
Fumaric acid esters - British Association of Dermatologists

... be marketed and sold in the UK. In the absence of a license, the drug may still be prescribed in the UK, provided there is funding available locally to pay for it. Additionally, there must be a clear body of evidence to confirm that the drug is effective for the condition in question and that safety ...
LABORATORY DETECTION OF TRIMETHYLAMINURIA ( TMAU
LABORATORY DETECTION OF TRIMETHYLAMINURIA ( TMAU

... • Trimethylamine (TMA) is a gas at body temperature and has a strong, pungent, offensive, fishy odor. – At low concentrations it may be perceived as “foul” or “unpleasant.” – Reported to be found in all body fluids. • “Fish odor syndrome” should not be used—only ~10% of our TMAU-positive individuals ...
Timing is Everything - Elliott G. Gross, M.D
Timing is Everything - Elliott G. Gross, M.D

... accompanying allodynia using a very early treatment paradigm where treatment was initiated while symptoms were still mild. Methods.— This was an open-label prospective, outpatient study of adult migraineurs who had screened positive for cutaneous allodynia and typically experienced moderate to sever ...
Idiopathic Thrombocytopenic Purpura
Idiopathic Thrombocytopenic Purpura

... „ Bone marrow bx in patients older than 60 to r/o MDS • Other groups lower the age of BMBx to 40 • Platelet auto-antibodies: Test characteristics are not good enough at this point to make them clinically useful • Remember that the platelets are completely functional and therefore the rate of major b ...
Etanercept in the treatment of recalcitrant enteropathic arthritis
Etanercept in the treatment of recalcitrant enteropathic arthritis

... In view of persistent unbearable pain and swelling of the left knee with severe secondary osteoarthritis, a left total knee replacement was done in the same year. Intraoperatively, there was active synovitis of the left knee and histopathological examination of the synovial tissue revealed ‘rice bod ...
ELCC 2014 European Lung Cancer Conference Scientific Meeting
ELCC 2014 European Lung Cancer Conference Scientific Meeting

... targeted agent. She interpreted available data for first-line treatment to conclude that patients should not be selected for EGFR therapy based on clinical characteristics. This may not be the case in second- (including maintenance) or third-line therapy where patients with both EGFR wt and mutant t ...
No adverse physiological responses to infrared whole body
No adverse physiological responses to infrared whole body

... research [1,2]. Pain and stiffness diminish and grip 1 Introduction strength and joint function (range of motion) improve Heat treatment in patients with rheumatic disorders is after local heat therapy [3]. Although beneficial a well-accepted form of physiotherapy treatment. effects of total body hy ...
Infliximab/Plasmapheresis in Vanishing Bile Duct
Infliximab/Plasmapheresis in Vanishing Bile Duct

... approach. Despite our patient’s death, TNF-a blockade and/or plasmapheresis may still offer therapeutic alternatives for VBDS, although we acknowledge that follow-up is short, his condition was grave, and confounding therapies were used, making it difficult to know which, if any, were effective. His ...
Provisional PDF - Pediatric Rheumatology
Provisional PDF - Pediatric Rheumatology

19-51028-000-TMS-Therapy-Level-II-and-External
19-51028-000-TMS-Therapy-Level-II-and-External

... These results demonstrate that the health benefits of TMS Therapy outweigh the risks, therefore meeting the criterion that TMS improves net health outcome. 4. The technology must be as beneficial as the established alternative treatments. Since head-to-head comparative trials were not conducted betw ...
Goals of ARV therapy
Goals of ARV therapy

... Assessments of rates of non adherence to treatment range from 20% to 80%, with the average rate of 50%. Adherence rate in IDUs (40% - 80%) and non-IDUs (30% - 70%) are similar. ...
Tips, tricks and know how for treating sleep disorders in neurology
Tips, tricks and know how for treating sleep disorders in neurology

... his arms. He asks you if it will keep getting worse ...
Evaluating the Headache Patient in an Ophthalmic Practice
Evaluating the Headache Patient in an Ophthalmic Practice

... with and without contrast can be performed if the patient is claustrophobic or if MRI cannot be obtained. Neurological visual field defects also require neuroimaging. Bitemporal defects, especially those that respect the vertical meridian, require imaging of the sella. MRI of the sella with and with ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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