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Patient information: Hemorrhoids
Patient information: Hemorrhoids

... Pain resulting from the formation of blood clots (thrombi) within hemorrhoids Leakage of rectal contents (fecal soilage) Bleeding — A common symptom of hemorrhoidal disease is painless bleeding that occurs with bowel movements. At the end of defecation, bright red blood may coat the stool, streak to ...
Atypical and Conventional Antipsychotic Drugs in Treatment
Atypical and Conventional Antipsychotic Drugs in Treatment

... The purported advantages of second-generation or ‘atypical’ antipsychotics relative to first-generation antipsychotics have not been examined in patients with a first episode of schizophrenia. This flexible-dose study examined efficacy and safety in a randomized, doubleblind, 52-week trial, comparin ...
Blepharitis Disease and Its Management
Blepharitis Disease and Its Management

... Location: “Right, left or both eyes?” Blepharitis usually is bilateral, but any associated chalazion (stye) is often unilateral. Duration: “When did symptoms start?” Days or several months ago? Seasonal symptoms, such as those experienced during the spring or fall, may be associated with allergy dis ...
Hyaluronic Acid for Treatment of Osteoarthritis of
Hyaluronic Acid for Treatment of Osteoarthritis of

... shown intra-articular HA to be superior. [11,12] Intra-articular HA has also been compared to intra-articular glucocorticoids. It seems that the benefits from each injection are somewhat similar; there were greater benefits of HA at some time points, although these benefits did not appear to be sust ...
ELECTRONIC SUBMISSION FOR CONSIDERATION IN THE
ELECTRONIC SUBMISSION FOR CONSIDERATION IN THE

... be used. Second line immunomodulation therapy includes rituximab and cyclophosphamide, both having been associated with benefit.5, 17, 18, 23 Second line treatment is increasingly used early in the course of treatment because first line therapy often shows a slow or incomplete response. ...
Linda S. Van Alstyne, Kendra L. Harrington and Esther M. Haskvitz
Linda S. Van Alstyne, Kendra L. Harrington and Esther M. Haskvitz

... lower urinary tract symptoms (LUTS) have a high incidence of depression and helplessness.5 Primary symptoms include pelvic, genital, or perineal pain with associated bladder dysfunction, including LUTS, and sexual dysfunction.6,7 Additional symptoms may include dysuria, increased urinary frequency, ...
Fulminant Form of Mitochondrial Myopathy, Encephalopathy, Lactic
Fulminant Form of Mitochondrial Myopathy, Encephalopathy, Lactic

... for the diagnosis of mitochondrial disorders, in which organs with high rate of oxidative metabolism, e.g., the gut, heart, brain, and peripheral nerves, are affected. Of the variety of clinical syndromes associated with mitochondrial dysfunction, the patient’s illness is best characterized as MELAS ...
Graded activity, gradual exposure in vivo, and cognitive
Graded activity, gradual exposure in vivo, and cognitive

... focuses on the cognitive path, rather than on the emotional path. In CTIP, patients are thought to learn and behave in rational ways. This implies that they must have the skills to critically reflect on their own common-sense model of their back pain problem and relate new information to the model. ...
A P ijopp Indian Journal of Pharmacy Practice
A P ijopp Indian Journal of Pharmacy Practice

... SADHS, physical activity was measured compared to other countries. It is not surprising that the survey shows very high levels of inactivity, especially in urban settings, with 48% of men and 63 % women in South Africa being inactive. This data is extremely important to set the trend in understandin ...
Editorial Therapeutic approaches to familial Mediterranean fever
Editorial Therapeutic approaches to familial Mediterranean fever

... whether colchicine therapy itself plays a role with this increment; our policy is to perform an amniocentesis at 4-5 months of gestation (21). We do not find a substantial reason to recommend ceasing therapy with colchicine prior to conception as well. Regarding the outcome of offspring of FMF males ...
US Hereditary Angioedema Association Medical Advisory Board
US Hereditary Angioedema Association Medical Advisory Board

... review at home are strongly encouraged (see Table E1 in this article’s Online Repository at www.jaci-inpractice.org).19 The information should be discussed and reviewed during follow-up visits. In addition to education about HAE, it is important that patients are provided guidance about navigating t ...
Clostridium difficile– Associated Disease
Clostridium difficile– Associated Disease

... cessation of the suspected causative antibiotic.23 Although stopping the antibiotic may be effective, the reason the antibiotic was prescribed in the first place should be considered, and monitoring for recurrence or worsening of the underlying infection is essential. Oral metronidazole, 250 to 500 ...
ABSTrACTS POSTErS AbstrActs Posters p01
ABSTrACTS POSTErS AbstrActs Posters p01

... part of the humerus. She was treated with fluconazole and intensive debridement. Both patients were asymptomatic without infection recurrence at the final follow up. Conclusions: Our study of septic arthritis has demonstrated that the predominant causative agent of septic arthritis was Staphylococcu ...
Waltham Forest
Waltham Forest

... treatment is requested but for which no agreement exists (or is believed not to exist). There are a number of reasons why no agreement exists including treatments which are new interventions or drugs which become available in year, or because the treatment or condition for which the treatment is req ...
Porphyria - American Porphyria Foundation
Porphyria - American Porphyria Foundation

... synthetase, the enzyme which limits the rate of the porphyrin/heme biosynthetic pathway. The exact mechanism by which hematin produces symptomatic improvement in patients with acute episodes of the hepatic porphyrias has not been ...
Allergy and Asthma - One Airway, One Disease
Allergy and Asthma - One Airway, One Disease

... frequently preceding that of asthma. One 23-year follow-up study demonstrated that subjects with allergic rhinitis had more than a 3-fold increased risk of developing asthma than those without this nasal condition. In addition, many patients who have allergic rhinitis also have bronchial hyper-respo ...
COMMITTEE OPINION
COMMITTEE OPINION

... by preventing fibrin degradation and are effective treatments for patients with chronic AUB. They have been shown to reduce bleeding in these patients by 30–55% (12, 13). Tranexamic acid effectively reduces intraoperative bleeding and the need for transfusion in surgical patients and is likely effec ...
Aspergilloma in an Open Chest Cavity
Aspergilloma in an Open Chest Cavity

... symptoms due to severe, progressive pulmonary hypertension with right ventricular failure.’ Nifedipine has been used monary hypertension. In pure sion ...
An explanation for the apparent dissociation between clinical
An explanation for the apparent dissociation between clinical

... Objective. Achieving remission is the aim of treatment in rheumatoid arthritis (RA). This should represent minimal arthritis activity and ensure optimal disease outcome. However, we have previously demonstrated a high prevalence of imaging-detected synovial inflammation in RA patients who were in cl ...
rhinitis
rhinitis

... sitting exams, who have severe symptoms which are not eased by other treatments). Steroids usually work well to reduce inflammation. A short course is usually safe. ...
low-dose naltrexone (ldn) fact sheet
low-dose naltrexone (ldn) fact sheet

... with uncertainty as to fill and provenance; the result of this licensing partnership is that KRS is now offering LDN in a formulated, quality-controlled, tablet, previously unavailable in the market. As noted, KRS Global Biotechnology, Inc. (“KRS”) is licensed (#PH23506a) with each individual state ...
Rimcure film-coated tablet ENG SmPC
Rimcure film-coated tablet ENG SmPC

... such as thrombocytopenia, purpura, haemolytic anaemia, dyspnoea and asthma-like attacks, shock or renal failure as these are side effects that rifampicin may provoke in exceptional cases. Patients developing such reactions must never again be treated with rifampicin. Rimcure should be withdrawn if o ...
VARICELLA IN IMMUNOCOMPROMISED CHILDREN AT THE
VARICELLA IN IMMUNOCOMPROMISED CHILDREN AT THE

... acyclovir at 500 mg/m2/dose given as a onehour infusion every 8 hours; but only one patient completed the 7- day IV therapy. 3 patients were given oral acyclovir at 60-100 mg/kg/day, 4 to 5 times a day, for 7 days. These patients were started on the oral form due to financial constraints. Of these 3 ...
Agent Based Modeling of Atherosclerosis: A Concrete Help in
Agent Based Modeling of Atherosclerosis: A Concrete Help in

... figure 2 one can observe about 20 foam cells per µl at the end of in silico follow up. This leads to a small atherogenesis process due to the high level of LDL and therefore high level of oxidized LDL. Ox-LDL in this situation stimulates the immune system humoral response through macrophages presenta ...
Chapter 96 - Disorders of the Anorectum
Chapter 96 - Disorders of the Anorectum

... The symptoms of nonthrombosed external and nonprolapsing internal hemorrhoids can be ameliorated by the standard regimen—warm water, analgesics, stool softeners, and high-fiber diet (WASH)—aimed at combating the problems that led to the hemorrhoids’ formation (Box 96-2). Anal canal pressures decreas ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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