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Prescribing Information
Prescribing Information

... response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials. (1.1) • Metastatic non-small cell lung cancer who have disease progression during or following platinum-containing chemothera ...
The Efficacy of Traditional Chinese Medicine on
The Efficacy of Traditional Chinese Medicine on

... be some use of acupuncture, which would be beneficial in patients who are not histamine sensitive when needles are inserted. This precaution can help practitioners understand that some use of acupuncture may be more contraindicated than the use of Chinese ...
PT Intervention/Examination in Geriatrics
PT Intervention/Examination in Geriatrics

Coding and Reimbursement Guide
Coding and Reimbursement Guide

... candidates for curative surgery or radiation therapy. ABRAXANE is indicated for the first-line treatment of patients with metastatic adenocarcinoma of the pancreas, in combination with gemcitabine. ...
document
document

Migraine Treatment From A to Z
Migraine Treatment From A to Z

... Triptans are helpful for moderate as well as more severe migraines. Certain patients may tolerate one triptan better than others and it is worthwhile to try several in an individual patient. Triptans are an excellent choice for migraine patients who are not at risk for coronary artery disease (CAD). ...
Embrace Life
Embrace Life

... safety and long-lasting effectiveness, which have been documented in numerous clinical articles and presentations. During the procedure, unique cooling mechanisms protect healthy tissue and enable more BPH tissue to be removed than other office-based procedures. When compared to various drug therapi ...
Pediatric Asthma Update
Pediatric Asthma Update

Pediatr Infect Dis J 2007 Aug 26(8) 728 32
Pediatr Infect Dis J 2007 Aug 26(8) 728 32

... and their onset generally coincides with underlying disease. The onset, length, and severity of aphthous-like ulcers is determined by the conditions or defects that have caused them. The correction of responsible factors may cause healing and prevent relapses. Several kinds of drugs can cause aphtho ...
Full Prescribing Information
Full Prescribing Information

... Based on the dosing utilized in the original pivotal study described herein, the recommended dosage at the start of therapy is not more than 0.005 mg/kg given as a daily subcutaneous injection. The dosage may be increased to not more than 0.01 mg/kg/day after 4 weeks according to individual patient ...
The practical management of refractory schizophrenia the Maudsley
The practical management of refractory schizophrenia the Maudsley

... poorly evidenced treatments – such as high-dose or multiple antipsychotic combinations – are often used in preference to clozapine (13, 14). In addition, we found that the long delay before starting clozapine hardly changed in our mental health services in the 10 years following the first NICE guidel ...
Does Extent of Resection of a Glioblastoma Matter?
Does Extent of Resection of a Glioblastoma Matter?

... lymph nodes. With use of these more radical approaches, the local recurrence rates were lowered to an unprecedented level of , 10%. However, 3-year overall survival remained only about 50% and not appreciably different from what it had been with mastectomy alone. The cost of these major anatomic res ...
Pediatric Gastroenteritis: Is That IV Really Necessary?
Pediatric Gastroenteritis: Is That IV Really Necessary?

...  May be an adjunct to determine dehydration severity category for patients presenting with AGE  May be added to a treatment algorithm to predict longer LOS and need for IV hydration ...
NICE | Provider of national guidance and advice to improve health
NICE | Provider of national guidance and advice to improve health



... measures. Most studies involve single referral centers using cross-sectional and retrospective analyses of small numbers of patients with treatment-refractory disease observed for relatively short time periods. In addition, widely disparate inclusion criteria have complicated the assessment of treat ...
Surgical Face Masks Worn by Patients with Multidrug
Surgical Face Masks Worn by Patients with Multidrug

... that hospitalization, rather than treatment nonadherence, conferred a sixfold greater relative risk for the acquisition of MDRTB by patients (5), whereas another study in Latvia revealed that previous hospitalization was a highly significant risk factor for MDR-TB (odds ratio, 18.33; P , 0.002) (6). ...
Pharmacologic Treatment of Spasticity in Children and Adolescents
Pharmacologic Treatment of Spasticity in Children and Adolescents

... formally addressed whether diazepam improved motor function. Ataxia and drowsiness were identified in the side-effect profile of most studies. ...
Acute otitis media in children: Epidemiology, pathogenesis, clinical
Acute otitis media in children: Epidemiology, pathogenesis, clinical

... not experience a type 1 hypersensitivity reaction (urticaria or anaphylaxis), we suggest one of the following: Cefdinir (14 mg/kg per day in 1 or 2 doses; maximum dose 600 mg/day) Cefpodoxime (10 mg/kg per day once daily; maximum dose 800 mg/day) Cefuroxime (cefuroxime axetil suspension: 30 mg/kg pe ...
A stepwise approach to management of acne
A stepwise approach to management of acne

... Acne should be considered a chronic disease. Like many other chronic diseases, such as asthma or rheumatoid arthritis, treatment should be aimed at both settling the acute symptoms (papules, pustules, nodules, cysts, etc) and preventing relapse. This step-up, step-down approach will hopefully simpli ...
Spasticity, Mobility Problems and Multiple Sclerosis
Spasticity, Mobility Problems and Multiple Sclerosis

... movement, some muscles relax while others contract. Spasticity occurs when this coordination is impaired and too many muscles contract at the same time. MS-related spasticity can occur with active movement or be present at rest. It can cause a leg to lock up and refuse to bend. Spasms may be spontan ...
Acute treatment of migraine headache
Acute treatment of migraine headache

... one should foster a therapeutic alliance with the patient. Most patients have not had this type of alliance with a care giver and will appreciate and benefit from it. Patients should understand that they need to participate in their own care, avoid migraine triggers, get regular sleep, meals, exerci ...
The Troubled Personality
The Troubled Personality

... Not successful with schizophrenic but still being used on them Results in death in 1 of 1000 patients, memory loss often lasts 4+ weeks, and for some it’s permanent Wardens in mental hospitals use it as threat for controlling patients No statistics prove or disprove the argument that it prevents sui ...
Emergence of Pan-drug resistance amongst gram negative bacteria
Emergence of Pan-drug resistance amongst gram negative bacteria

... years.9 Colistin is the drug of choice for treatment of patients having severe infections due to these bacteria. Colistin usage, in parts of the world with high prevalence of XDR Gram negative bacteria has resulted in reports of colistin resistant.10-12 As expected with any other antibiotic, increas ...
Treatment of CFS: the USA Experience
Treatment of CFS: the USA Experience

... light melatonin onset, patients whose result was later than 22 hours were more likely to respond to treatment. Methylphenidate (ritalin) in CFS 10 mg BID study in 60 patients, placebo control: 17% reported decreased fatigue, 22% improvement in concentration. ..further studies needed. Modafinil not h ...
Variations in Dinitrochlorobenzene Responsivity in Untreated Leprosy
Variations in Dinitrochlorobenzene Responsivity in Untreated Leprosy

... for the discordant finding is non-comparability of patients, i.e., our EN L patients were untreated and had active ENL at the time of DNCB sensitization; those of Turk and Waters ( 11 ) were treated and had a history of EN L but evidently not active ENL at the time of sensitization. In leprosy the r ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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