Chapter 1
... The secondary structure of a protein is defined as a local spatial structure of a certain peptide segment, that is, the relative positions of backbone atoms of this peptide segment. H-bonds are responsible for stabilizing the secondary structure. ...
... The secondary structure of a protein is defined as a local spatial structure of a certain peptide segment, that is, the relative positions of backbone atoms of this peptide segment. H-bonds are responsible for stabilizing the secondary structure. ...
Getting things where they need to go: Protein Targeting
... Floating many Sar1p in top leaflet makes it ‘bigger’ than the bottom one. Results --> bulge that can more easily interact with coat proteins. Drin, G, and B. Antonny (2005) News and Views: Helices sculpt membrane. Nature vol: 437 ...
... Floating many Sar1p in top leaflet makes it ‘bigger’ than the bottom one. Results --> bulge that can more easily interact with coat proteins. Drin, G, and B. Antonny (2005) News and Views: Helices sculpt membrane. Nature vol: 437 ...
Gene Section BAG3 (Bcl-2 associated athanogene 3) Atlas of Genetics and Cytogenetics
... BAG3 is a cytoplasmatic protein, particularly concentrated in the rough endoplasmic reticulum; a slightly different molecular weight, a doublet form or a nuclear localisation can be observed in some cell types and/or following cell exposure to stressors. ...
... BAG3 is a cytoplasmatic protein, particularly concentrated in the rough endoplasmic reticulum; a slightly different molecular weight, a doublet form or a nuclear localisation can be observed in some cell types and/or following cell exposure to stressors. ...
Effect of osmotic pressure on cells
... Cells produce, move in slime trails. Unrelated organism glide: myxobacteria, flavobacteria, cyanobacteria; appear to glide by different mechanisms. Cells glide in groups, singly, and can reverse directions. ...
... Cells produce, move in slime trails. Unrelated organism glide: myxobacteria, flavobacteria, cyanobacteria; appear to glide by different mechanisms. Cells glide in groups, singly, and can reverse directions. ...
Biological Membranes
... Computer programs can be used to predict the number of membrane proteins Estimated percentage of membrane proteins is substantial: 20–30% of all genes may encode membrane proteins This trend is found throughout all domains of life including archaea, bacteria, and eukaryotes Function of many genes un ...
... Computer programs can be used to predict the number of membrane proteins Estimated percentage of membrane proteins is substantial: 20–30% of all genes may encode membrane proteins This trend is found throughout all domains of life including archaea, bacteria, and eukaryotes Function of many genes un ...
PROTEINS
... signatures for a specific function. The presence of the same motif in different proteins with similar functions clearly indicates that these useful combinations of secondary structures have been conserved in evolution. To date, hundreds of motifs have been cataloged and proteins are now classified a ...
... signatures for a specific function. The presence of the same motif in different proteins with similar functions clearly indicates that these useful combinations of secondary structures have been conserved in evolution. To date, hundreds of motifs have been cataloged and proteins are now classified a ...
Molecular Protein-Tectons in Synthetic Biology and Nanotechnology
... building blocks and networks with regulatory and structural functions, which did not previously exist in nature.1,2 Realizing such protein-based modular biological devices resembling a close systematic link to the so-called BioBricks, we design biogenic protein tectons within cells showing complex d ...
... building blocks and networks with regulatory and structural functions, which did not previously exist in nature.1,2 Realizing such protein-based modular biological devices resembling a close systematic link to the so-called BioBricks, we design biogenic protein tectons within cells showing complex d ...
proteome
... This involves developing a representation of how units of secondary structure come together to form ‘domains’*. • *compact regions of structure within the large protein structure. ...
... This involves developing a representation of how units of secondary structure come together to form ‘domains’*. • *compact regions of structure within the large protein structure. ...
Glucose/Galactose Binding Protein (GGBP)
... differentiation, chromosomal segregation, and circadian rhythm. In humans, CK1s have been linked to neurodegenerative diseases and cancer. We are investigating regulation of CK1 activity by phosphorylation, using yeast CK1 protein kinases as models. We have previously identified phosphorylation site ...
... differentiation, chromosomal segregation, and circadian rhythm. In humans, CK1s have been linked to neurodegenerative diseases and cancer. We are investigating regulation of CK1 activity by phosphorylation, using yeast CK1 protein kinases as models. We have previously identified phosphorylation site ...
File
... fMet-tRNAf is placed in the P site during formation of the 70S initiation complex Initiation factors IF1 and IF3 join the 30S subunit to preventing 30S from prematurely binding 50S IF2, a GTPase, binds GTP to change shape and enable binding of IF2 to fMet-tRNAf. The IF2-GTP- fMet-tRNAf complex bi ...
... fMet-tRNAf is placed in the P site during formation of the 70S initiation complex Initiation factors IF1 and IF3 join the 30S subunit to preventing 30S from prematurely binding 50S IF2, a GTPase, binds GTP to change shape and enable binding of IF2 to fMet-tRNAf. The IF2-GTP- fMet-tRNAf complex bi ...
Inhibitors of Protein Synthesis
... Inhibitors of Protein Synthesis • Bacterial cells are 50% protein by dry weight – Inhibition of protein synthesis leads to cessation of growth or cell death – Bacterial 70S ribosomes differ sufficiently from eukaryotic ribosomes to allow selective toxicity • Other properties of the antibiotics still ...
... Inhibitors of Protein Synthesis • Bacterial cells are 50% protein by dry weight – Inhibition of protein synthesis leads to cessation of growth or cell death – Bacterial 70S ribosomes differ sufficiently from eukaryotic ribosomes to allow selective toxicity • Other properties of the antibiotics still ...
PowerPoint Presentation - Modeling the Organism: The Cell in
... A Few Questions for Thought • Describe the life cycle of Saccharomyces cerevisiae, noting relationships between mitotic growth, the alternation of generations, meiosis, conjugation and spore formation. •Review the compartments and cytoskeleton of the eukaryotic cell, comparing and contrasting what ...
... A Few Questions for Thought • Describe the life cycle of Saccharomyces cerevisiae, noting relationships between mitotic growth, the alternation of generations, meiosis, conjugation and spore formation. •Review the compartments and cytoskeleton of the eukaryotic cell, comparing and contrasting what ...
Week 16
... • Four letter code for the compound, case insensitive (Ex: 2HHB) • Always start with a numeric followed by alphanumeric • Each compound may have multiple chains, a chain ID is denoted by compound ID followed by ‘:’ and chain identifier (Ex: 2HHB:A) • If the compound has only one chain (monomer), ...
... • Four letter code for the compound, case insensitive (Ex: 2HHB) • Always start with a numeric followed by alphanumeric • Each compound may have multiple chains, a chain ID is denoted by compound ID followed by ‘:’ and chain identifier (Ex: 2HHB:A) • If the compound has only one chain (monomer), ...
Enzymes and CellMemb.. - hrsbstaff.ednet.ns.ca
... 7. Which letter represents the activity of an enzyme that could be found in the stomach? 8. What happens to enzyme activity when the pH is higher or lower than the optimal pH? Why does this happen? 9. Match the structure with the correct letter from the diagram: _______ cholesterol ______ cytoskelet ...
... 7. Which letter represents the activity of an enzyme that could be found in the stomach? 8. What happens to enzyme activity when the pH is higher or lower than the optimal pH? Why does this happen? 9. Match the structure with the correct letter from the diagram: _______ cholesterol ______ cytoskelet ...
The Concept of Functional Constraint
... DNA regions, in which a mutation is likely to affect function, have a more stringent functional constraint than regions devoid of function ...
... DNA regions, in which a mutation is likely to affect function, have a more stringent functional constraint than regions devoid of function ...
3 types of protein transport
... The pH regulates the activity of hydrolytic enzymes Lysosome contains many types of hydrolytic enzymes These are only active in an acidic environment ...
... The pH regulates the activity of hydrolytic enzymes Lysosome contains many types of hydrolytic enzymes These are only active in an acidic environment ...
2-BuildingBlocks
... molecules. These non-covalent bonds involve the AA side chains. Selecting from those listed in the box, which type(s) of amino acids would: A. form ionic bonds with negatively charged DNA. _________ B. form hydrogen bonds with water. __________ C. help hold together two water-soluble proteins.______ ...
... molecules. These non-covalent bonds involve the AA side chains. Selecting from those listed in the box, which type(s) of amino acids would: A. form ionic bonds with negatively charged DNA. _________ B. form hydrogen bonds with water. __________ C. help hold together two water-soluble proteins.______ ...
week 5 no answers
... Denaturants => cause large, structural change and loss of function i. Usually cause abrupt loss of function -> protein unfolding is cooperative. ii. Important- > do not break covalent Denaturants will distrupt hydrophobic interactions. Eg. _____________________? ___________________________? Experime ...
... Denaturants => cause large, structural change and loss of function i. Usually cause abrupt loss of function -> protein unfolding is cooperative. ii. Important- > do not break covalent Denaturants will distrupt hydrophobic interactions. Eg. _____________________? ___________________________? Experime ...
Chapter 1
... GOLGI, peroxi-, lyso-, or endosomes, mitochondria, chloroplasts and to some extent the nucleus. In the transmission of information and solutes across the biological membrane integral membrane proteins play a central role. The importance of these proteins is reflected in the genomes sequenced thus fa ...
... GOLGI, peroxi-, lyso-, or endosomes, mitochondria, chloroplasts and to some extent the nucleus. In the transmission of information and solutes across the biological membrane integral membrane proteins play a central role. The importance of these proteins is reflected in the genomes sequenced thus fa ...
Passive Transport
... Molecules spread out from an area of high concentration to an area of low concentration. ...
... Molecules spread out from an area of high concentration to an area of low concentration. ...
Selectively Permeable Membranes Reading and Pics
... membranes. At any given moment, a particular substance may exist in higher or lower concentrations on one side of the membrane versus the other. Such a difference in concentration is called a gradient. The particular type of transport used for a particular substance depends on the direction of its c ...
... membranes. At any given moment, a particular substance may exist in higher or lower concentrations on one side of the membrane versus the other. Such a difference in concentration is called a gradient. The particular type of transport used for a particular substance depends on the direction of its c ...
Compartimentation, biological membranes
... of fibroblast cells in connective tissue) - regulated: the release of these proteins is initiated by different neural and hormonal stimuli. The exocytosis is triggered by a rise in the intracellular calcium level (example: hormone production of endocrine glands). ...
... of fibroblast cells in connective tissue) - regulated: the release of these proteins is initiated by different neural and hormonal stimuli. The exocytosis is triggered by a rise in the intracellular calcium level (example: hormone production of endocrine glands). ...
Lecture 5: Powerpoint
... Hydrophobic interactions among hydrophobic R groups. Disulphide bridges that form strong, stable bonds between parts of the molecule ...
... Hydrophobic interactions among hydrophobic R groups. Disulphide bridges that form strong, stable bonds between parts of the molecule ...