What is bioinformatics? A proposed definition and overview of the field
... strings of the four base-letters comprising genes, each typically 1,000 bases long. The GenBank (2) repository of nucleic acid sequences currently holds a total of 12.5 billion bases in 11.5 million entries (all database figures as of April 2001). At the next level are protein sequences comprising s ...
... strings of the four base-letters comprising genes, each typically 1,000 bases long. The GenBank (2) repository of nucleic acid sequences currently holds a total of 12.5 billion bases in 11.5 million entries (all database figures as of April 2001). At the next level are protein sequences comprising s ...
Relative Requirements for Magnesium of Protein and Chlorophyll
... photoheterotrophic Euglena are grown with different amounts of Mg initially present in the medium, both the rate of growth and total yield, as measured by apparent optical density, are affected (Fig. IA). Provided that exponentially growing cells were used to inoculate the cultures, no lag phase was ...
... photoheterotrophic Euglena are grown with different amounts of Mg initially present in the medium, both the rate of growth and total yield, as measured by apparent optical density, are affected (Fig. IA). Provided that exponentially growing cells were used to inoculate the cultures, no lag phase was ...
propy: a tool to generate various modes of
... features for proteins and peptides covered by the current version of propy is summarized in Table 1. These features can be divided into five groups, each of which has been independently predicting protein- and peptide-related problems by using machine-learning methods. The first group includes three ...
... features for proteins and peptides covered by the current version of propy is summarized in Table 1. These features can be divided into five groups, each of which has been independently predicting protein- and peptide-related problems by using machine-learning methods. The first group includes three ...
Winter Final Study Guide
... 37. The cell above needs to get rid of CO2. State whether it will use simple diffusion, facilitated diffusion, or active transport, and defend your answer. ...
... 37. The cell above needs to get rid of CO2. State whether it will use simple diffusion, facilitated diffusion, or active transport, and defend your answer. ...
Lecture 13 - 14 Conformation of proteins Conformation of a protein
... Because of the large size of the molecules, proteins exhibit many properties that are colloidal in nature. Proteins, like amino acids, are amphoteric and contain both acidic and basic groups. They possess electrically charged groups and hence migrate in an electric field. ...
... Because of the large size of the molecules, proteins exhibit many properties that are colloidal in nature. Proteins, like amino acids, are amphoteric and contain both acidic and basic groups. They possess electrically charged groups and hence migrate in an electric field. ...
Bio102 Problems
... 10. It’s not surprising that meat spoils quickly if left at room temperature for just a few days, due to the growth of a large number of bacteria. However, if that meat is first treated with large amounts of salt (making beef jerky), it can be left at room temperature indefinitely without spoiling. ...
... 10. It’s not surprising that meat spoils quickly if left at room temperature for just a few days, due to the growth of a large number of bacteria. However, if that meat is first treated with large amounts of salt (making beef jerky), it can be left at room temperature indefinitely without spoiling. ...
Supplementary Table S2 (doc 37K)
... might affect catalytic activity, but also might cause a conformational change by creating a new disulphide bridges. In fact, the in silico analysis predicted that the newly introduced C in position 381 could form a disulphide bridge with C18, completely destroying GBA structure. ...
... might affect catalytic activity, but also might cause a conformational change by creating a new disulphide bridges. In fact, the in silico analysis predicted that the newly introduced C in position 381 could form a disulphide bridge with C18, completely destroying GBA structure. ...
Awan, Ali: In Silico Transfer of Ligand Binding Function between Structurally Analogous Proteins
... protein modification has been used to alter protein performance for industrial purposes. It has been possible to change the rates, temperatures and pHs at which enzymes operate, to increase efficiency and applicability. Further, it has become possible to modify not only protein performance, but even ...
... protein modification has been used to alter protein performance for industrial purposes. It has been possible to change the rates, temperatures and pHs at which enzymes operate, to increase efficiency and applicability. Further, it has become possible to modify not only protein performance, but even ...
Protein Structures - the University of California, Davis
... General principle of X-ray crystallography applied to proteins: 1) We need a crystal 2) From the diffraction pattern, we get the crystal organization 3) From the diffraction intensities, we get the electron densities 4) Once the electron density map we fit a structure that matches with this density ...
... General principle of X-ray crystallography applied to proteins: 1) We need a crystal 2) From the diffraction pattern, we get the crystal organization 3) From the diffraction intensities, we get the electron densities 4) Once the electron density map we fit a structure that matches with this density ...
Protein Structures: Experiments and Modeling
... General principle of X-ray crystallography applied to proteins: 1) We need a crystal 2) From the diffraction pattern, we get the crystal organization 3) From the diffraction intensities, we get the electron densities 4) Once the electron density map we fit a structure that matches with this density ...
... General principle of X-ray crystallography applied to proteins: 1) We need a crystal 2) From the diffraction pattern, we get the crystal organization 3) From the diffraction intensities, we get the electron densities 4) Once the electron density map we fit a structure that matches with this density ...
S1 Text Section A Annotation by structural analysis In case of aldose
... Comparison of knockout predictions between the L. infantum iAS142 and L. major iAC560 models Given below is a table (Table SC) that compares the knockout predictions of the iAS142 with the iAC560 model lethal predictions and their relation to known phenotypes identified from experiments. The results ...
... Comparison of knockout predictions between the L. infantum iAS142 and L. major iAC560 models Given below is a table (Table SC) that compares the knockout predictions of the iAS142 with the iAC560 model lethal predictions and their relation to known phenotypes identified from experiments. The results ...
Protein translocation across mitochondrial membranes
... dase equivalent to the bacterial leader peptidase(' . imported after urea denaturation remained in an Re-export from the matrix to the intermembrane unfolded state in tight association with the mutated mtspace was found to be defective in yeast cells that have hsp70("). Apparently mt-hsp70 has a dua ...
... dase equivalent to the bacterial leader peptidase(' . imported after urea denaturation remained in an Re-export from the matrix to the intermembrane unfolded state in tight association with the mutated mtspace was found to be defective in yeast cells that have hsp70("). Apparently mt-hsp70 has a dua ...
Lecture 4 - Biological Molecules Part II
... • A single amino acid change in primary structure can affect a protein’s structure and ability to function – HOWEVER if the substitution is similar (a polar a.a. for another polar a.a. for example) there may be little to no difference in the final 3D shape ...
... • A single amino acid change in primary structure can affect a protein’s structure and ability to function – HOWEVER if the substitution is similar (a polar a.a. for another polar a.a. for example) there may be little to no difference in the final 3D shape ...
PEPTIDE HORMONES
... Sizes, origins and fate: Due to the force of custom, “peptide hormones” is a collective name that has been applied to peptides, polypeptides and proteins that all function as hormones. The name “factor” has also been given to some of these peptides and originates from a time when their peptide/prot ...
... Sizes, origins and fate: Due to the force of custom, “peptide hormones” is a collective name that has been applied to peptides, polypeptides and proteins that all function as hormones. The name “factor” has also been given to some of these peptides and originates from a time when their peptide/prot ...
Drug development
... • Identify protein targets where the three-dimensional structure can be elucidated. • Prioritise targets based on Bioverse networks and functional annotation. • Computationally predict inhibitors against the targets: - small molecule inhibitors are predicted using our docking with dynamics protocol ...
... • Identify protein targets where the three-dimensional structure can be elucidated. • Prioritise targets based on Bioverse networks and functional annotation. • Computationally predict inhibitors against the targets: - small molecule inhibitors are predicted using our docking with dynamics protocol ...
Cell transport with the environment
... Osmosis: The process of diffusion involving only the water molecule. Water molecules still move from an area of high concentration to an area of low concentration without the involvement of ATP. ...
... Osmosis: The process of diffusion involving only the water molecule. Water molecules still move from an area of high concentration to an area of low concentration without the involvement of ATP. ...
Chapter summaries
... 14. Enzyme inhibition represents a vital mechanism to controlling catalytic function. In vivo inhibitors bind tightly to enzymes causing a loss of activity and regulation of activity. 15. A common form of enzyme inhibition involves the competition between substrate and inhibitor for an active site. ...
... 14. Enzyme inhibition represents a vital mechanism to controlling catalytic function. In vivo inhibitors bind tightly to enzymes causing a loss of activity and regulation of activity. 15. A common form of enzyme inhibition involves the competition between substrate and inhibitor for an active site. ...
Lecture 1 Cell Biology
... Channel protein: has a channel through which water or other solute can pass ...
... Channel protein: has a channel through which water or other solute can pass ...
PSI - European Bioinformatics Institute
... • Given a set of uncharacterised sequences, we usually want to know: ...
... • Given a set of uncharacterised sequences, we usually want to know: ...
3-3, 3-4, 3-5 membrane, diff, trans
... What is the difference between active transport and passive transport? a. Active requires energy and passive does not b. Passive requires energy and active does not c. Passive moves big materials into the cell and active does not d. B and C ...
... What is the difference between active transport and passive transport? a. Active requires energy and passive does not b. Passive requires energy and active does not c. Passive moves big materials into the cell and active does not d. B and C ...
Steroidogenesis - Delta State University
... • Regulated by steroid acute transport regulate protein (StAR) – Channel protein ...
... • Regulated by steroid acute transport regulate protein (StAR) – Channel protein ...
Protein Molecules in Solution
... nitrogens or to mereaptan groups. An interesting case not shown in table 3 is Pb ion which, like Zn or Cu, is bound strongly to mereaptan groups. On the other hand, Pb shows a much greater affinity for carboxyl than for amine groups; the opposite preference is characteristic of Zn and Cu. There are ...
... nitrogens or to mereaptan groups. An interesting case not shown in table 3 is Pb ion which, like Zn or Cu, is bound strongly to mereaptan groups. On the other hand, Pb shows a much greater affinity for carboxyl than for amine groups; the opposite preference is characteristic of Zn and Cu. There are ...