Inderal (propranolol hydrochloride) Tablets Rx only
... The mechanism of the antihypertensive effect of propranolol has not been established. Factors that may contribute to the antihypertensive action include: (1) decreased cardiac output, (2) inhibition of renin release by the kidneys, and (3) diminution of tonic sympathetic nerve outflow from vasomotor ...
... The mechanism of the antihypertensive effect of propranolol has not been established. Factors that may contribute to the antihypertensive action include: (1) decreased cardiac output, (2) inhibition of renin release by the kidneys, and (3) diminution of tonic sympathetic nerve outflow from vasomotor ...
The Eclectic Materia Medica, Pharmacology and Therapeutics by
... membranes with vascular excitation and determination of blood; hyperemia; chilly sensations; skin hot and dry, with small, frequent pulse. Early stage of fevers with or without restlessness. When septic processes prevail it is only relatively indicated. Action.—The effects of aconite, considered fro ...
... membranes with vascular excitation and determination of blood; hyperemia; chilly sensations; skin hot and dry, with small, frequent pulse. Early stage of fevers with or without restlessness. When septic processes prevail it is only relatively indicated. Action.—The effects of aconite, considered fro ...
Sumatriptan Succinate Injection - Pack Insert
... cardiac adverse reactions, including acute myocardial infarction, occurring within a few hours following administration of sumatriptan injection. Some of these reactions occurred in patients without known CAD. 5-HT1 agonists, including sumatriptan injection, may cause coronary artery vasospasm (Prin ...
... cardiac adverse reactions, including acute myocardial infarction, occurring within a few hours following administration of sumatriptan injection. Some of these reactions occurred in patients without known CAD. 5-HT1 agonists, including sumatriptan injection, may cause coronary artery vasospasm (Prin ...
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... analyzing the activity of targeted immune cells varied as well, making interpretation difficult. Two of the five studies showed activity of the measured immune cells to be significantly stimulated, while three did not. In a highly publicized study, researchers ran a clinical study on 302 healthy peo ...
... analyzing the activity of targeted immune cells varied as well, making interpretation difficult. Two of the five studies showed activity of the measured immune cells to be significantly stimulated, while three did not. In a highly publicized study, researchers ran a clinical study on 302 healthy peo ...
effect of cytochrome p450 2d6 and 3a enzyme inhibition on
... lesser degree, CYP2D6 are responsible for the oxidative metabolism of oxycodone (Lalovic et al. 2004). Due to its CYP-mediated metabolism, oxycodone might be prone to drug-drug interactions. Since strong opioids like oxycodone have potential to cause dangerous adverse effect, e.g. respiratory depres ...
... lesser degree, CYP2D6 are responsible for the oxidative metabolism of oxycodone (Lalovic et al. 2004). Due to its CYP-mediated metabolism, oxycodone might be prone to drug-drug interactions. Since strong opioids like oxycodone have potential to cause dangerous adverse effect, e.g. respiratory depres ...
... volumes and respiratory rates) vary with the dose of drugs administered. In addition, tramadol's peak effect is dependent upon formation of the M1 metabolite and is likely to occur at a later time than that of morphine, the active comparator. Central nervous system (CNS) effects Tramadol has been no ...
... cause a Pa-ET,CO2 gradient [24]. In the same study the effect of 4 mg·kg-1 acetazolamide on the ventilatory response to CO2 during normoxaemia was also investigated: utilizing the technique of dynamic end-tidal forcing (DEF) [25], decreases in the CO2 sensitivities of the peripheral (Sp) and central ...
Antiatherogenic Properties of Naringenin, a Citrus Flavonoid
... decrease atherosclerotic lesion area in apoE-deficient mice (39). The mechanisms whereby flavonoids inhibit LDL oxidation are unclear. They may protect ␣-tocopherol in LDL from oxidation, possibly by being preferentially oxidized themselves, or they may reduce the formation or release of free radica ...
... decrease atherosclerotic lesion area in apoE-deficient mice (39). The mechanisms whereby flavonoids inhibit LDL oxidation are unclear. They may protect ␣-tocopherol in LDL from oxidation, possibly by being preferentially oxidized themselves, or they may reduce the formation or release of free radica ...
Crystal Methamphetamine Use in New South Wales
... of methamphetamine, a synthetic central nervous system stimulant. It affects the neurotransmitters that regulate feelings of excitement, euphoria and alertness and can cause users to feel confident and energetic. However, there are many negative side effects associated with its use; these may be str ...
... of methamphetamine, a synthetic central nervous system stimulant. It affects the neurotransmitters that regulate feelings of excitement, euphoria and alertness and can cause users to feel confident and energetic. However, there are many negative side effects associated with its use; these may be str ...
Use of Codeine in Children
... infants, as in a minority of cases it may cause CNS depression and apnea and death.5,6 Other patients In adults who are ultra-rapid metabolizers, even small doses of codeine have lead to loss of consciousness and respiratory failure requiring naloxone infusion. Blood levels of morphine were 20 to ...
... infants, as in a minority of cases it may cause CNS depression and apnea and death.5,6 Other patients In adults who are ultra-rapid metabolizers, even small doses of codeine have lead to loss of consciousness and respiratory failure requiring naloxone infusion. Blood levels of morphine were 20 to ...
Pharmacology and the Nursing Process, 4th ed. Lilley/Harrington
... Mosby items and derived items © 2005, 2002 by Mosby, Inc. ...
... Mosby items and derived items © 2005, 2002 by Mosby, Inc. ...
Buprenorphine (with or without naloxone)
... Buprenorphine alleviates opioid withdrawal symptoms and cravings (Raisch et al 2002) while helping to reduce illicit use by reducing the positive effects from ‘use on top’. The effect of buprenorphine to reduce illicit ‘use on top’ may occur in two ways: crosstolerance and pharmacological antagonism ...
... Buprenorphine alleviates opioid withdrawal symptoms and cravings (Raisch et al 2002) while helping to reduce illicit use by reducing the positive effects from ‘use on top’. The effect of buprenorphine to reduce illicit ‘use on top’ may occur in two ways: crosstolerance and pharmacological antagonism ...
levocarb CR
... There have been rare reports of adverse reactions, including hypertension and dyskinesia, resulting from the concomitant use of tricyclic antidepressants and levodopa/carbidopa preparations. (For patients receiving monoamine oxidase inhibitors, see CONTRAINDICATIONS). Isoniazid: Isoniazid may reduce ...
... There have been rare reports of adverse reactions, including hypertension and dyskinesia, resulting from the concomitant use of tricyclic antidepressants and levodopa/carbidopa preparations. (For patients receiving monoamine oxidase inhibitors, see CONTRAINDICATIONS). Isoniazid: Isoniazid may reduce ...
NICE CG96 - Neuropathic pain The pharmacological management
... commissioned by the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme and due to report in 20102, was used to inform this guideline where appropriate. This clinical guideline covers the management of neuropathic pain conditions in adults (aged 18 or over) in ...
... commissioned by the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme and due to report in 20102, was used to inform this guideline where appropriate. This clinical guideline covers the management of neuropathic pain conditions in adults (aged 18 or over) in ...
министерство здравоохранения республики беларусь
... 46. By means of a receptor competitive action include drugs. Variants of the answer: a) non-steroidal anti-inflammatory drugs; b) beta-blockers; c) a loop diuretic; d) nitrates; e) quinolones. 47. The drugs that are connected to the proteins more than 90 %, with a decrease of 10 %. Variants of the a ...
... 46. By means of a receptor competitive action include drugs. Variants of the answer: a) non-steroidal anti-inflammatory drugs; b) beta-blockers; c) a loop diuretic; d) nitrates; e) quinolones. 47. The drugs that are connected to the proteins more than 90 %, with a decrease of 10 %. Variants of the a ...
acetaminophen and codeine phosphate tablets
... Concentration-Efficacy Relationships – The minimum effective analgesic concentration will vary widely among patients, especially among patients who have been previously treated with potent agonist opioids. The minimum effective analgesic concentration of codeine for any individual patient may increa ...
... Concentration-Efficacy Relationships – The minimum effective analgesic concentration will vary widely among patients, especially among patients who have been previously treated with potent agonist opioids. The minimum effective analgesic concentration of codeine for any individual patient may increa ...
product monograph isoptin sr
... Atypical lens changes and cataracts were observed in beagle dog studies at high doses. This has been concluded to be species-specific for the beagle dog. (These ophthalmological changes were not seen in a second study.) No similar changes have been observed in long-term prospective human ophthalmolo ...
... Atypical lens changes and cataracts were observed in beagle dog studies at high doses. This has been concluded to be species-specific for the beagle dog. (These ophthalmological changes were not seen in a second study.) No similar changes have been observed in long-term prospective human ophthalmolo ...
July 28, 2014 Margaret A. Hamburg, MD
... teething. 37 Regarding safety, the Panel was aware of several cases of methemoglobinemia related to use of benzocaine “in high doses” in infants and children ages 12 days to 6 years. 38,39,40 Notably, none of these cases were related to teething medication, but instead involved the use of benzocaine ...
... teething. 37 Regarding safety, the Panel was aware of several cases of methemoglobinemia related to use of benzocaine “in high doses” in infants and children ages 12 days to 6 years. 38,39,40 Notably, none of these cases were related to teething medication, but instead involved the use of benzocaine ...
Pharmacological Significance of Synthetic Heterocycles
... coenzymes, nucleic acids, ATP and serotonin [9]. Why does nature utilize heterocycles? The answer to this question is provided by the fact that heterocyles are able to get involved in an extraordinarily wide range of reaction types. Depending on the pH of the medium, they may behave as acids or base ...
... coenzymes, nucleic acids, ATP and serotonin [9]. Why does nature utilize heterocycles? The answer to this question is provided by the fact that heterocyles are able to get involved in an extraordinarily wide range of reaction types. Depending on the pH of the medium, they may behave as acids or base ...
a new antiarrhythmic compound potent class iii
... effective than other anti-arrhythmic drugs for this purpose13. This drug, however, never enjoyed mainstream success because of modest efficacy, a potentially high risk of torsade-de- pointes in some patients14, and the time commitment for physicians and other personnel. Older drugs, such as quinidin ...
... effective than other anti-arrhythmic drugs for this purpose13. This drug, however, never enjoyed mainstream success because of modest efficacy, a potentially high risk of torsade-de- pointes in some patients14, and the time commitment for physicians and other personnel. Older drugs, such as quinidin ...
Effects of Temperature and Drugs on Frog Heart
... Although after acute caffeine ingestion, an increase in heart rate49,50, or no change12,13,25,35 has been reported, the commoner response may be slight decrease in heart rate, in laboratory settings10,14,15,23,27,29,30,51,52,53, lasting approximately 75 min after caffeine ingestion in borderline hyp ...
... Although after acute caffeine ingestion, an increase in heart rate49,50, or no change12,13,25,35 has been reported, the commoner response may be slight decrease in heart rate, in laboratory settings10,14,15,23,27,29,30,51,52,53, lasting approximately 75 min after caffeine ingestion in borderline hyp ...
Clearing of Metabolic Waste via Enterohepatic Recirculation Table
... estrogen into the bloodstream and increasing the animal’s exposure to this hormone. In a study to investigate the pharmacokinetics of oestriol in plasma in the dog, it was found that the concentration-time curve strongly suggested the existence of enterohepatic recirculation. The average relative co ...
... estrogen into the bloodstream and increasing the animal’s exposure to this hormone. In a study to investigate the pharmacokinetics of oestriol in plasma in the dog, it was found that the concentration-time curve strongly suggested the existence of enterohepatic recirculation. The average relative co ...
Oxytocin (Oxt) /ˌɒksɨˈtoʊsɪn/ is a mammalian neurohypophysial
... Social behavior and wound healing: Oxytocin is also thought to modulate inflammation by decreasing certain cytokines. Thus, the increased release in oxytocin following positive social interactions has the potential to improve wound healing. A study by Marazziti and colleagues used heterosexual coupl ...
... Social behavior and wound healing: Oxytocin is also thought to modulate inflammation by decreasing certain cytokines. Thus, the increased release in oxytocin following positive social interactions has the potential to improve wound healing. A study by Marazziti and colleagues used heterosexual coupl ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.