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9-1-13 The Chronicle - Paterson Counseling Center
9-1-13 The Chronicle - Paterson Counseling Center

... Some drugs, such as marijuana and heroin, have a similar structure to chemical messengers, called neurotransmitters, which are naturally produced by the brain. Because of this similarity, these drugs are able to "fool" the brain's receptors and activate nerve cells to send abnormal messages. Other d ...
A Brief Overview of Drugs of Abuse (pages 1-17) Read Pages 1
A Brief Overview of Drugs of Abuse (pages 1-17) Read Pages 1

... The Addictive Process: The addictive process involves use, misuse, abuse and dependence. Regardless of the chemical, the process is the same. After use of a psychoactive chemical, the central nervous system is affected and causes physiological and mental changes to take place. It is the mental chang ...
Antidepressants, Antipsychotics, Antianxiety
Antidepressants, Antipsychotics, Antianxiety

... Targets benzodiazepine receptors with less effects on skeletal muscles and seizure threshold ...
FOUR MAJOR TARGETS FOR DRUGS
FOUR MAJOR TARGETS FOR DRUGS

... These metabolic transformations, such as oxidation, reduction and hydrolysis, produce a molecule that is suitable for conjugation. Those of importance in the metabolism of psychotropic drugs are CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A4, the last being responsible for the metabolism of more than 90 ...
What`s Inside Worksheet
What`s Inside Worksheet

... 1. What category of drug is yours? (Depressant, Stimulant, Hallucinogens, Opiate..etc) 2. What neurotransmitter does your drug effect? 3. Is your drug an Agonist or Antagonist (does it mimic a neurotransmitter or block a neurotransmitter? 4. What are the physical/physiological effects? 5. How many d ...
Drug Action - people.vcu.edu
Drug Action - people.vcu.edu

... Example: pilocarpine was selective and potent for excitation of parasympathetic nervous system, while atropine was capable of blocking this effect! …… both interact with same component of the cell ...
File
File

... Benzodiazepines are used primarily as anxiolytics, hypnotics, antiepileptics, and anesthetics  The indications for their use are anxiety, muscle spasm, seizures, and treatment of acute alcohol withdrawal symptoms  Prolonged use of > 4-6 weeks, >60-80mg/day develop dependence.  Anxiety, irritabili ...
Cannabinoids
Cannabinoids

... What is the endogenous ligand? Are these receptors responsible for the CNS effects of D9THC? ...
Designer Drug Update - Commonwealth Prevention Alliance
Designer Drug Update - Commonwealth Prevention Alliance

... Mitragyna tree native to Southeast Asian ...
File
File

... think you need the drug and cannot live without it. Your whole life revolves around getting the next dose.  Withdrawal – drug specific physical or mental symptoms if ...
cnspharmacology
cnspharmacology

... (thereby increasing neurotransmitter concentration at the synaptic cleft). TCAs do not block dopamine transport. Approximate time frame for a therapeutic effect is 2-3 weeks. In general, TCAs are very lipid soluble, highly bound to plasma proteins, resulting in a large volume of distribution and con ...
DRUGS - PBworks
DRUGS - PBworks

... It’s easier to use by IV Provides high that lasts 3 – 4 hours – deep sense of well being, drowsiness ...
DRUG OF ABUSE
DRUG OF ABUSE

... • Neonates born to mothers physiologically dependent on opioids require special management of withdrawal symptoms ...
Extra slides: substance abuse
Extra slides: substance abuse

... Withdrawal • The signs and symptoms that occur when a drug is stopped or dose lowered • Both physiological and psychological processes contribute ...
Opioid Anelgesics
Opioid Anelgesics

... – Changes in cellular adaptive responses but not receptor numbers – Tolerance is marked for CNS actions such as analgesia, euphoria, respiratory depression ...
Anaesthetic implications of psychoactive drugs
Anaesthetic implications of psychoactive drugs

... the basal ganglia. These so-called, extra-pyramidal syndromes include akathisia, Parkinsonian symptoms, and tardive dyskinesia. A rare but significant side-effect of both the typical and the atypical antipsychotic drugs is the neuroleptic malignant syndrome. First described in the 1960s, it is chara ...
Drugs Hanson 10 - Lackawanna College
Drugs Hanson 10 - Lackawanna College

... popular with young people. • It enhances sensory input and is referred to as an entactogen (a combination of psychedelic and stimulant effects) and it releases both serotonin and dopamine. • While dependence can occur, it tends to be unusual. • Withdrawal includes depression and sleep disruption tha ...
The Science of Recovery - AAP
The Science of Recovery - AAP

12 Allergy Drugs
12 Allergy Drugs

... b-agonists: activate adenylcyclase enzyme = increases c-AMP (cyclic adenosine monophosphate) c-AMP activates phosphorylation of HO-containing amino acids (tyrosine, serine and threonine) which causes the enzyme to change shape = release of Ca2+ ions from their storage sites = relaxation of muscles ...
Chapter 16 Cholinesterase Inhibitors
Chapter 16 Cholinesterase Inhibitors

... (may be severe) that cannot be explained by structural or chemical abnormalities May occur with diarrhea, constipation, or both Considered IBS when symptoms have been present for 12 weeks over the past year ...
Document
Document

... and compare with the high dose behavioral and subjective effects. 2) Present the evidence that the mesolimbic dopamine pathway plays a major role in the rewarding aspects of cocaine. a. Table 11.2 b. Regions of NA c. Knockout mice? i. Model implies more than mesolimbic pathway involved but……….. d. H ...
File - NAMI Santa Cruz County
File - NAMI Santa Cruz County

... the mechanisms by which drug seeking behaviors are consolidated into compulsive use: -long persistence of relapse risk -drug-associated cues control behavior ...
Document
Document

... years, other medicines that are more effective and with fewer side effects have almost eliminated cocaine's use for medicinal purposes. Cocaine is a powerful, short-acting stimulant that affects the central nervous system. Its effects, which include increased heart rate, blood pressure and respirati ...
NEUROTRANSMITTERS
NEUROTRANSMITTERS

... a wall because the feet won't stop. Emotional symptoms include an elevated depression rate. Emotional expressiveness appears reduced because facial muscles do not properly reflect the person's emotions. Drugs like L-dopa can alleviate symptoms of Parkinson's by having the same effects as dopamine. E ...
Drugs - Wando High School
Drugs - Wando High School

...  Koren’s Story ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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