Pharmacokinetics & Pharmacodynamics
... Provides basis for rational therapeutic uses and the design of new, superior therapeutic agents ...
... Provides basis for rational therapeutic uses and the design of new, superior therapeutic agents ...
What Are The Causes Of Addiction
... What Are The Causes Of Addiction? Doctors say there is a link between the repeated use of an addictive substance and how the human brain experiences pleasure - its use has a nice reward, leading to further and more frequent use. The addictive substance, be it nicotine, alcohol or some drug actually ...
... What Are The Causes Of Addiction? Doctors say there is a link between the repeated use of an addictive substance and how the human brain experiences pleasure - its use has a nice reward, leading to further and more frequent use. The addictive substance, be it nicotine, alcohol or some drug actually ...
Chapter 8 GI Drugs Quiz Yourself 1. H2 receptors are special
... 1. H2 receptors are special histamine receptors located in the gastric parietal cells lining the stomach. When stimulated, these receptors trigger the release of gastric acid. H2 blocker drugs block H2 receptors and prevent the release of gastric acid. 2. The trade name Antivert combines the syllabl ...
... 1. H2 receptors are special histamine receptors located in the gastric parietal cells lining the stomach. When stimulated, these receptors trigger the release of gastric acid. H2 blocker drugs block H2 receptors and prevent the release of gastric acid. 2. The trade name Antivert combines the syllabl ...
药理概论1
... Drug addiction is defined as the compulsive, out-of-control drug use, despite negative consequences. Drug abuse: any use of a drug for non-medical purposes. ...
... Drug addiction is defined as the compulsive, out-of-control drug use, despite negative consequences. Drug abuse: any use of a drug for non-medical purposes. ...
Medicines additional questions LT Scotland
... What function does a receptor have? What effect does an agonist have when it binds to a receptor? What effect does an antagonist have when it binds to a receptor? ...
... What function does a receptor have? What effect does an agonist have when it binds to a receptor? What effect does an antagonist have when it binds to a receptor? ...
18 Wilson substance abuse 2006
... • cause mood elevation, decreased anxiety, sedation, analgesia, respiratory depression, pupil constriction • heroin crosses the blood-brain barrier more easily, and so has ...
... • cause mood elevation, decreased anxiety, sedation, analgesia, respiratory depression, pupil constriction • heroin crosses the blood-brain barrier more easily, and so has ...
Document
... are G-protien binding receptors a1 Activate phospholipase C, which catalyzes the release of IP3 and DAG from membrane ...
... are G-protien binding receptors a1 Activate phospholipase C, which catalyzes the release of IP3 and DAG from membrane ...
Psychotropic Drugs – Critical Thinking - KEY
... 6. Individuals who are under the influence of cocaine experience elevated heart and respiratory rates that can become life threatening. Which are of the brain is causing these physiological changes? _____________ (Medulla; Hindbrain) In which drug category should cocaine be classified? _____________ ...
... 6. Individuals who are under the influence of cocaine experience elevated heart and respiratory rates that can become life threatening. Which are of the brain is causing these physiological changes? _____________ (Medulla; Hindbrain) In which drug category should cocaine be classified? _____________ ...
Sites of drug metabolism
... One of the second generation antihistamines , Fexofenadine is claimed to cause less sedation. In contrast, some antihistamines are used for their CNS depressant activity because a significant proportion of the administrated dose is crossing the blood-brain barrier binding to the histamine H1 re ...
... One of the second generation antihistamines , Fexofenadine is claimed to cause less sedation. In contrast, some antihistamines are used for their CNS depressant activity because a significant proportion of the administrated dose is crossing the blood-brain barrier binding to the histamine H1 re ...
Pharmacology Objectives 5
... 2) Understand the major mechanisms through which genetic variation can alter responses to drugs. The most common type of variation change is a change in a single nucleotide pair termed a single nucleotide polymorphism or SNP. If SNPs occur in the coding region of a gene they can have qualitative eff ...
... 2) Understand the major mechanisms through which genetic variation can alter responses to drugs. The most common type of variation change is a change in a single nucleotide pair termed a single nucleotide polymorphism or SNP. If SNPs occur in the coding region of a gene they can have qualitative eff ...
20.b) SYMPATHETIC NERVOUS SYSTEM, ALFA AND BETA
... INDIRECT - ACTING ADRENERGIC AGONISTS A. AMPHETAMINE Actions: marked central stimulatory action (not only NOR release, but also the release of 5-HT and dopamine in CNS), - increase of NOR release, - MAO inhibitor, - uptake inhibitor. Increase blood pressure. Peripheral actions are mediated primarily ...
... INDIRECT - ACTING ADRENERGIC AGONISTS A. AMPHETAMINE Actions: marked central stimulatory action (not only NOR release, but also the release of 5-HT and dopamine in CNS), - increase of NOR release, - MAO inhibitor, - uptake inhibitor. Increase blood pressure. Peripheral actions are mediated primarily ...
Medicine&Drugs5-Depressants(PPT-LS)
... By determining the level of green color present one can determine the ethanol concentration.. The ethanol absorbed by the dichromate solution can be calibrated against blood alcohol levels The reaction is somewhat time dependent, therefore it is necessary to compare colors rather than titrate the so ...
... By determining the level of green color present one can determine the ethanol concentration.. The ethanol absorbed by the dichromate solution can be calibrated against blood alcohol levels The reaction is somewhat time dependent, therefore it is necessary to compare colors rather than titrate the so ...
SSRIs
... -not more effective in tx depression * fewer dangerous side effects * effective in a wide range of affective problems lack of selfesteem, fear of failure, OCD, ...
... -not more effective in tx depression * fewer dangerous side effects * effective in a wide range of affective problems lack of selfesteem, fear of failure, OCD, ...
Experimental method and procedure
... the velocity at 1 to 2 bubbles each second; Trace a length of normal curve. ...
... the velocity at 1 to 2 bubbles each second; Trace a length of normal curve. ...
DrugLecture2001
... into the nucleus accumbens • DA receptor antagonists injected attenuate i.v. selfinto nucleus accumbens of rats administration • 6-OHDA lesions of the nucleus attenuate i.v. selfaccumbens of rats* administration ...
... into the nucleus accumbens • DA receptor antagonists injected attenuate i.v. selfinto nucleus accumbens of rats administration • 6-OHDA lesions of the nucleus attenuate i.v. selfaccumbens of rats* administration ...
drug 2012 - Dr. Timothy Hain`s Home Page
... Author’s experience – Useful for motion intolerance and Meniere’s. •Kingma H, Bonink M, Meulenbroeks A, Konijnenberg H. Dose-dependent effect of betahistine on the vestibulo-ocular reflex: a double-blind placebo controlled study in patients with paroxysmal vertigo. Acta Otolaryngologica 117(5):641-6 ...
... Author’s experience – Useful for motion intolerance and Meniere’s. •Kingma H, Bonink M, Meulenbroeks A, Konijnenberg H. Dose-dependent effect of betahistine on the vestibulo-ocular reflex: a double-blind placebo controlled study in patients with paroxysmal vertigo. Acta Otolaryngologica 117(5):641-6 ...
Sympatholytics
... tends to cause blood to pool in the lower extremities. However, several reflexes, including sympathetically mediated venoconstriction minimize this pooling and maintain cerebral perfusion. If these reflex actions do not occur, then orthostatic hypotension could result. ...
... tends to cause blood to pool in the lower extremities. However, several reflexes, including sympathetically mediated venoconstriction minimize this pooling and maintain cerebral perfusion. If these reflex actions do not occur, then orthostatic hypotension could result. ...
1 The Neuromuscular Junction: Pharmacology
... b. Enhancers (agonists). Cholinergic agonists that act at NMJ’s include carbachol and decamethonium. They maintain the open state of the ligand-gated channels that are integral to the ACh receptor. Acetylcholine itself is also, of course, an agonist of the ACh receptor but molecules like ACh and dec ...
... b. Enhancers (agonists). Cholinergic agonists that act at NMJ’s include carbachol and decamethonium. They maintain the open state of the ligand-gated channels that are integral to the ACh receptor. Acetylcholine itself is also, of course, an agonist of the ACh receptor but molecules like ACh and dec ...
Antipsychotics
... • Old antiphsychotics /neuroleptics are D2 dopamine receptor antagonists. Although they are also effective antagonists at ACh, 5-HT, NE receptors. ...
... • Old antiphsychotics /neuroleptics are D2 dopamine receptor antagonists. Although they are also effective antagonists at ACh, 5-HT, NE receptors. ...
Opioid Analgesics
... Impaired kidney function may cause prolonged drug action and accumulation Nonceiling drug ...
... Impaired kidney function may cause prolonged drug action and accumulation Nonceiling drug ...
Depression in Primary Care
... SSRI with dual mechanism of action Blocks serotonin reuptake through the serotonin transporter Partial agonism of the 5-HT1A presynaptic receptor FDA indicated for MDD Thought to decrease the therapeutic lag of traditional SSRI’s Felt to have less sexual side effects compared to the other SSRI’s Com ...
... SSRI with dual mechanism of action Blocks serotonin reuptake through the serotonin transporter Partial agonism of the 5-HT1A presynaptic receptor FDA indicated for MDD Thought to decrease the therapeutic lag of traditional SSRI’s Felt to have less sexual side effects compared to the other SSRI’s Com ...
• Some Key Concepts from “Drugs and the Brain” – Fall 2008
... • acute and chronic effects of alcohol • effects of alcohol on fetal development • effects of light alcohol use • alcohol pharmacology: GABA, glutamate, adenosine • sedative-hypnotic drugs: alcohol, general anesthetics, inhalants, barbiturates, benzodiazepines, non- benzodiazepine pharmaceutical sed ...
... • acute and chronic effects of alcohol • effects of alcohol on fetal development • effects of light alcohol use • alcohol pharmacology: GABA, glutamate, adenosine • sedative-hypnotic drugs: alcohol, general anesthetics, inhalants, barbiturates, benzodiazepines, non- benzodiazepine pharmaceutical sed ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.