Zzzzzzz…. - The Cambridge MRCPsych Course
... • Also binds to dopamine receptors but this action less important in anxiety • 5-HT1A receptors are inhibitory autoreceptors that reduce release of 5-HT and other mediators • Also inhibit NA in locus coeruleus neurons so reduce arousal • Buspirone takes days-weeks to have an effect (?more complex ac ...
... • Also binds to dopamine receptors but this action less important in anxiety • 5-HT1A receptors are inhibitory autoreceptors that reduce release of 5-HT and other mediators • Also inhibit NA in locus coeruleus neurons so reduce arousal • Buspirone takes days-weeks to have an effect (?more complex ac ...
K2, Salvia, Khat, Toad Licking and More: A Look at Some
... New research shows that mephedrone and methylenedioxypyrovalerone act on the dopamine system in opposite ways. -Mephedrone causes the brain to release more dopamine (like methamphetamine). -Methylenedioxypyrovalerone is a dopamine reuptake inhibitor, increase concentrations and neurotransmission (li ...
... New research shows that mephedrone and methylenedioxypyrovalerone act on the dopamine system in opposite ways. -Mephedrone causes the brain to release more dopamine (like methamphetamine). -Methylenedioxypyrovalerone is a dopamine reuptake inhibitor, increase concentrations and neurotransmission (li ...
Serotonin Syndrome
... Serotonin is a chemical made in the body to help transport messages across brain cells (neurons) for the brain to function. Taking certain medicines at the same time can cause too much serotonin to build up in the body. This results in serotonin syndrome. Serotonin syndrome can have mild to severe s ...
... Serotonin is a chemical made in the body to help transport messages across brain cells (neurons) for the brain to function. Taking certain medicines at the same time can cause too much serotonin to build up in the body. This results in serotonin syndrome. Serotonin syndrome can have mild to severe s ...
Cholinergic–Anticholinergic Drug Interactions
... after consideration of potential pharmacodynamic interactions. The avoidance of drugs with anticholinergic properties (eg, bladder antispasmodics, sedating antihistamines, tricyclic antidepressants) minimizes the risk of cognitive impairment or other central nervous system side effects in patients w ...
... after consideration of potential pharmacodynamic interactions. The avoidance of drugs with anticholinergic properties (eg, bladder antispasmodics, sedating antihistamines, tricyclic antidepressants) minimizes the risk of cognitive impairment or other central nervous system side effects in patients w ...
VIEWS & REVIEWS - BMJ Press Releases
... in the 1970s—notoriously admitted that the administration had lied about the harmful effects of drugs and had manipulated media coverage of them for political advantage.3 Nearly 50 years later psychedelic drugs remain more legally restricted than heroin and cocaine, which are schedule 2, class A in ...
... in the 1970s—notoriously admitted that the administration had lied about the harmful effects of drugs and had manipulated media coverage of them for political advantage.3 Nearly 50 years later psychedelic drugs remain more legally restricted than heroin and cocaine, which are schedule 2, class A in ...
What School Staff Need to Know about Substance Abuse
... Many people begin to drink alcohol during adolescence and young adulthood. Alcohol consumption during this developmental period may have profound effects on brain structure and function. Heavy drinking has been shown to affect the neuropsychological performance (e.g., memory functions) of young peop ...
... Many people begin to drink alcohol during adolescence and young adulthood. Alcohol consumption during this developmental period may have profound effects on brain structure and function. Heavy drinking has been shown to affect the neuropsychological performance (e.g., memory functions) of young peop ...
Panic Disorder
... Recommendations: 3. Don’t give a benzodiazepine as the sole drug, either in acute phase or maintenance period (easier said than done) Rationale: It would be hard to discontinue and the danger of dependence would be real (‘iatrogenic dependence’) ...
... Recommendations: 3. Don’t give a benzodiazepine as the sole drug, either in acute phase or maintenance period (easier said than done) Rationale: It would be hard to discontinue and the danger of dependence would be real (‘iatrogenic dependence’) ...
03 Motor Symptoms PD SLIDES
... • Aim of treatment of motor symptoms is to restore dopamine levels • Treatment choice will depend on age, symptoms, comorbidities and patient wishes • As disease progresses the number of medications and adjustments required will increase • It is extremely important that medications are managed well ...
... • Aim of treatment of motor symptoms is to restore dopamine levels • Treatment choice will depend on age, symptoms, comorbidities and patient wishes • As disease progresses the number of medications and adjustments required will increase • It is extremely important that medications are managed well ...
HESS 525 - The Citadel
... C. a trace of bull's blood. D. cocaine. 23. The International Olympics Committee first established rules disqualifying competitors who failed or who refused to take drug tests in A. 1936. B. 1968. C. 1980. D. 1992. 24. During and after World War II, it was found that malnourished people could gain w ...
... C. a trace of bull's blood. D. cocaine. 23. The International Olympics Committee first established rules disqualifying competitors who failed or who refused to take drug tests in A. 1936. B. 1968. C. 1980. D. 1992. 24. During and after World War II, it was found that malnourished people could gain w ...
9-12-04 Intro Terminol
... • Dose is the exact amount of a drug that is administered in order to produce and effect – The graph of the response versus a given dose is the dose-response curve – The response is often proportional to the dose • Not always • May hit a ceiling above which no therapeutic effect is observed, but adv ...
... • Dose is the exact amount of a drug that is administered in order to produce and effect – The graph of the response versus a given dose is the dose-response curve – The response is often proportional to the dose • Not always • May hit a ceiling above which no therapeutic effect is observed, but adv ...
Document
... -poor metabolizers no pain relief from codeine prodrug for morphine catalyzed by CYP2D6 4-hydroxylase Other genetic variations- 1:3000 occurrence atypical cholinesterasewill not metabolize topical anasthetic succinycholine these individuals may stay “frozen” for days or weeks- need to be screened fo ...
... -poor metabolizers no pain relief from codeine prodrug for morphine catalyzed by CYP2D6 4-hydroxylase Other genetic variations- 1:3000 occurrence atypical cholinesterasewill not metabolize topical anasthetic succinycholine these individuals may stay “frozen” for days or weeks- need to be screened fo ...
Psy 5260 – Summer I 2009
... Short half-life (approx. one hour) Metabolites have longer half-life (approx. 8 hours) ...
... Short half-life (approx. one hour) Metabolites have longer half-life (approx. 8 hours) ...
Epilim - Melbourne Neurosurgery
... spread of seizure activity in the motor part of the brain. It does this by increasing the content in the brain of a substance(GABA) that inhibits signal transmission in the brains neurons HOW LONG BEFORE IT WORKS ? This depends on lots of factors but the drug does not reach a stable concentration in ...
... spread of seizure activity in the motor part of the brain. It does this by increasing the content in the brain of a substance(GABA) that inhibits signal transmission in the brains neurons HOW LONG BEFORE IT WORKS ? This depends on lots of factors but the drug does not reach a stable concentration in ...
Slide 1
... A. Schematic diagram of the main neurotransmitter pathways and their effects in the cortical–basal ganglia–thalamic circuits. The blue lines indicate neurons with excitatory effects; the black lines indicate inhibitory influences. The internal (medial) segment of the globus pallidus (MGP) and the zo ...
... A. Schematic diagram of the main neurotransmitter pathways and their effects in the cortical–basal ganglia–thalamic circuits. The blue lines indicate neurons with excitatory effects; the black lines indicate inhibitory influences. The internal (medial) segment of the globus pallidus (MGP) and the zo ...
Frenxit Prescribing Information
... Adults : Usually 2 tablets daily (morning and noon). In severe cases the morning dose may be increased to 2 tablets. Elderly patients : 1 tablet in the morning. Maintenance dose : Usually 1 tablet in the morning. In cases of insomnia or severe restlessness additional treatment with a sedative in the ...
... Adults : Usually 2 tablets daily (morning and noon). In severe cases the morning dose may be increased to 2 tablets. Elderly patients : 1 tablet in the morning. Maintenance dose : Usually 1 tablet in the morning. In cases of insomnia or severe restlessness additional treatment with a sedative in the ...
Mephedrone Information Sheet
... Possession – up to a Maximum of 5 years imprisonment and/or unlimited fine Supply (selling) – up to a Maximum of 14 years imprisonment and/or unlimited fine The police will treat any white powder or capsule in the same way they do any other illegal substance. The likelihood is that the substance wil ...
... Possession – up to a Maximum of 5 years imprisonment and/or unlimited fine Supply (selling) – up to a Maximum of 14 years imprisonment and/or unlimited fine The police will treat any white powder or capsule in the same way they do any other illegal substance. The likelihood is that the substance wil ...
Not For Human Consumption - North Inner City Drugs Task Force
... These drugs are only being produced for sale in the last number of years In the short-term, there are not a lot of hard facts about them and their side effects and little is known about the longer term effects on people’s health These new products have not been tested or approved for ...
... These drugs are only being produced for sale in the last number of years In the short-term, there are not a lot of hard facts about them and their side effects and little is known about the longer term effects on people’s health These new products have not been tested or approved for ...
Enalaprilmaleate - McGraw-Hill
... pneumonitis, upper respiratory tract infection, asthma, bronchitis, difficulty breathing, loss of head hair, increased skin sensitivity to light, increased sweating, rash (possibly serious), swelling of tongue or throat, fever, increased appetite, or anaphylactoid reactions. Notify prescriber of all ...
... pneumonitis, upper respiratory tract infection, asthma, bronchitis, difficulty breathing, loss of head hair, increased skin sensitivity to light, increased sweating, rash (possibly serious), swelling of tongue or throat, fever, increased appetite, or anaphylactoid reactions. Notify prescriber of all ...
Street Drugs - Centegra Health System
... There are several different routes of administration for heroin. It can be injected which offers the greatest risks than other methods. This is typically called slamming, banging main lining or shooting up. They report a surge or euphoric rush followed by a dry mouth, warm flushed skin, heaviness o ...
... There are several different routes of administration for heroin. It can be injected which offers the greatest risks than other methods. This is typically called slamming, banging main lining or shooting up. They report a surge or euphoric rush followed by a dry mouth, warm flushed skin, heaviness o ...
File
... • Diethylcarbamazine is the drug of choice for filariasis. • It kills the microfilariae and has activity against adult worms. • Diethylcarbamazine is rapidly absorbed following oral administration with meals and is excreted mainly in the urine. • Adverse effects: • include fever, nausea, vomiting, a ...
... • Diethylcarbamazine is the drug of choice for filariasis. • It kills the microfilariae and has activity against adult worms. • Diethylcarbamazine is rapidly absorbed following oral administration with meals and is excreted mainly in the urine. • Adverse effects: • include fever, nausea, vomiting, a ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.