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A1986E936300001
A1986E936300001

drug-food interactions and role of pharmacist
drug-food interactions and role of pharmacist

... which can affect the activity of certain drugs. The half-lives of some medications can be significantly changed by alterations in urinary pH. Therefore, the half-life of acidic drugs will be extended in acidic urine because the drug is in its unionized form. However, the half-life of an acidic drug ...
Sheet#6,Dr.Alia,Marwh Nsour
Sheet#6,Dr.Alia,Marwh Nsour

... note : thalidomide involved in X category of drugs. X categeory mean that : drugs which included in it has a teratogenic effect so must not be used in pregnant women. Another example of drugs related to x category is isotretinoin ( related to "topical retenoids" ) ,, a common effective drug used to ...
Ecstasy - a quick guide to drugs and alcohol
Ecstasy - a quick guide to drugs and alcohol

... Interaction with other drugs Ecstasy can be dangerous when combined with any of the prescription antidepressant drugs called monoamine oxidase inhibitors (there are many brands of these). ...
Problem amphetamine and methamphetamine use
Problem amphetamine and methamphetamine use

... amphetamines (1) use since the introduction of these substances as medicines in the 1930s. The history of amphetamines use is the result of an interplay of global forces, such as the spread of recreational drug use in the 1960s and the arrival of heroin on the European drug scene in the 1970s, and l ...
Who Uses Illicit Drugs?
Who Uses Illicit Drugs?

... dry mouth, increased appetite, lowered blood pressure, mild muscular weakness • Users may experience severe anxiety, panic, paranoia, and psychosis ...
drug design and thalidomide - School of Medical Sciences
drug design and thalidomide - School of Medical Sciences

... The birth of modern Science and Pharmacology. • The 16th and 17th centuries were notable for the simultaneous development of physiology, chemistry and physics. • Physiologists documented the way in which the body functioned and chemists began to develop the technologies which permitted extractions, ...
On the Discovery and Development of Pimavanserin
On the Discovery and Development of Pimavanserin

... of clozapine in PDP therapy, it is infrequently used. There are two major problems with clozapine therapy in PDP: First, clozapine is not safe, even at the low doses used for PDP. It may still cause agranulocytosis [9] and, thus, requires frequent blood monitoring. Second, the histamine H1 antagonis ...
bupropion / Wellbutrin
bupropion / Wellbutrin

... simply switch to bupropion. If the initial antidepressant dose was relatively high, one may consider tapering the dose prior to adding or switching to bupropion. If switching, a washout period may be desirable to minimize side effects. Potential interactions: Since bupropion can cause a dose-depende ...
PATIENT MEDICATION INFORMATION Vibramycin
PATIENT MEDICATION INFORMATION Vibramycin

... This leaflet is a summary and will not tell you everything about this drug. Talk to your healthcare professional about your medical condition and treatment and ask if there is any new information about Vibramycin/Vibra-Tabs. What is Vibramycin/Vibra-Tabs used for?  Vibramycin/Vibra-Tabs is used to ...
PowerPoint Presentation - Lecture 9
PowerPoint Presentation - Lecture 9

... Aldosterone promotes Na retention & K excretion. Block aldosterone & Na excreted, but H2O & K retained - Used to treat HTN primarily, - but not a 1st line drug. Also used in heart failure. - SE = hyperkalemia & 1st dose hypotension (more common with comb. Diuretic & ACE inhibitor. ...
Advantages - pharmacist
Advantages - pharmacist

... therapeutic window for prolonged periods of time. • Reduced inter and intra patient variability. ...
to our crestor information package
to our crestor information package

... marketing its cholesterol-lowering drug, rosuvastatin, raise disturbing questions about how drugs enter clinical practice and what measures exist to protect patients from inadequately investigated medicines," according to his editorial. The Lancet's editorial position is that the data for Crestor’s ...
Investigator-Initiated, Pharma-Sponsored Clinical Trials in Human
Investigator-Initiated, Pharma-Sponsored Clinical Trials in Human

... Marketed Oncology Products (1/2004) • Single-arm, phase 2 trials using marketed drugs to treat a cancer different from that indicated in the approved labeling and using doses and schedules similar to those in the marketed drug labeling • Phase 1 oncology trials of marketed drugs if such therapy is a ...
ENGLISH VERSION (Eng)
ENGLISH VERSION (Eng)

... not the only manifestation of unfavorable consequences for fetus of a woman who took drugs during pregnancy [2, 4]. A term “functional teratogenesis” has been established in literature in recent years – malfunctions of organs and systems under influence of a teratogen on the fetal ontogenetic stage ...
- San Diego State University
- San Diego State University

... 8. Identifies factors that influence medication compliance 9. Performs appropriate monitoring before, during, and after specific drug regimens. 10. Monitors efficacy of drug/s evaluates the response and compliance of the client to the drugs/devices and provides interventions for side effects, and ma ...
File - the Drug Card Database
File - the Drug Card Database

... may ↓ serum salicylate levels. Urinary acidification ↑ reabsorption and may ↑ serum salicylate levels. Alkalinization of the urine or the ingestion of large amounts of antacids ↑ excretion and ↓ serum salicylate levels. May blunt the therapeutic response to diuretics, and antihypertensives. ↑ risk o ...
Anxiety Disorders
Anxiety Disorders

... • A selective nonbenzodiazepine anxiolytic • lacks anticonvulsant, muscle relaxant, hypnotic, motor or cognitive/memory impairment, and dependence properties. • Exact mechanism: Unknown • partial agonist of 5HTIA receptor → increases serotonin neurotransmission. • Lacks general CNS depressant effect ...
Antiparkinsonian drugs_E
Antiparkinsonian drugs_E

... DA by MAO-B and aldehyde dehydrogenase generate hydroxyl free radicals (˙OH) in the presence of ferrous iron (basal ganglia are rich in iron). Normally these radicals are quenched by glutathione and other endogenous antioxidants. Age-related (e.g. in atherosclerosis) and/or otherwise acquired defect ...
Pain Procedures and Medications: What You Need to Know
Pain Procedures and Medications: What You Need to Know

... pain and cancer pain effectively This was extended to treatment of chronic pain Addiction was thought to arise only rarely during legitimate treatment of pain Tolerance could be overcome by dose ...
Press Release GABA from reactive astrocytes in Alzheimer disease
Press Release GABA from reactive astrocytes in Alzheimer disease

... aged 65 or over have Alzheimer’s disease. In 2011, 7,600 elderly people with dementia lost their way back home and became homeless in Korea. However, to date, there has been no clear understanding of the mechanisms underlying dementia in Alzheimer’s disease. So far, neuronal death is the only propos ...
I. Angina Pectoris
I. Angina Pectoris

... drugs. Contraction is triggered by influx of calcium (which can be blocked by calcium channel blockers) through transmembrane calcium channels. The calcium combines with calmodulin to form a complex that converts the enzyme myosin light chain kinase to its active form (MLCK*). The latter phosphoryla ...
managing insomnia
managing insomnia

... active metabolites and little or no hangover effect. Longer acting benzodiazepines, such as diazepam and nitrazepam, are not usually recommended because they have a more prolonged action and may cause residual effects the following day.7 Adverse effects associated with benzodiazepine use include dro ...
Sceletium tortuosum and Mesembrine: A
Sceletium tortuosum and Mesembrine: A

... been  speculated  that  this  could  be  related  to  high  rates  of  obesity,  heart  disease,  stroke,   and  sleep  disorders  in  the  same  region  (Census  Bureau,  2011).  It  has  also  been  shown   that  women  are  twice ...
Sceletium tortuosum and Mesembrine: A
Sceletium tortuosum and Mesembrine: A

... been  speculated  that  this  could  be  related  to  high  rates  of  obesity,  heart  disease,  stroke,   and  sleep  disorders  in  the  same  region  (Census  Bureau,  2011).  It  has  also  been  shown   that  women  are  twice ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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