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Toward a Drug-Free University
Toward a Drug-Free University

... federal, state, and local regulations regarding substance abuse on campus. In order to comply with the law, the Drug and Alcohol Abuse Educational Notification must, at a minimum, include the following: (a) The annual distribution in writing to each employee, and to each student who is taking one or ...
Suicide Attempt by Ingestion High Doses of Risperidone, Citalopram
Suicide Attempt by Ingestion High Doses of Risperidone, Citalopram

... ingestion of 1120 mg citalopram. There are papers reporting survival after risperidone intake up to 300 mg doses. In our case 160 mg risperidone was ingested. Due to weak drug interaction between citalopram and risperidone and very low dosage of ingested paracetamol; drug plasma concentrations could ...
Research Report Series from the director:
Research Report Series from the director:

... thereby increasing neural activity in the nucleus accumbens. In the normal communication process, dopamine is released by a neuron into the synapse (the small gap between two neurons), where it binds to specialized proteins (called dopamine receptors) on the neigh­ boring neuron and sends a signal ...
Opioid Overdose 101 - Harm Reduction Coalition
Opioid Overdose 101 - Harm Reduction Coalition

... Semi-synthetic opioids: created from natural opioids such as hydromorphone, hydrocodone, oxycodone, heroin etc., ...
Bronchitis
Bronchitis

... amoxicillin-clavulanate), plus a macrolide, unless they live in an area with high S. pneumoniae resistance to macrolides. ...
oral presentation abuse of benzodiazepines among heroin addicts
oral presentation abuse of benzodiazepines among heroin addicts

... NARCOTICS ARE COMING IN ALL COUNTRIES IN TRANSITION MARIJUANA HEROIN COCAIN CRACK SINTETIC NARCOTICS- LSD, ECSTASY “Pod solncem demokratii rascveta¥t ne tolÝko gladiolusÝi no i marihuana.” Sergeí Dovlatov, Russian short-story writer and novelist. ...
Kratom Did you know? - Maryland Poison Center
Kratom Did you know? - Maryland Poison Center

... three cases of toxicity from kratom abuse this month alone, raising our concern that abuse of this drug might be on the rise. Kratom is most frequently abused for its euphoric effect or used by some to selftreat opioid withdrawal, as it is considered an alternative to opium. Recently, kratom has bee ...
A molecular basis of the therapeutic and psychoactive
A molecular basis of the therapeutic and psychoactive

... transduction in the cell membrane. The natural ligand of the 7TM receptor is an eicosanoid, arachidonylethanolamide (AEA), generated in the membrane and derived from arachidonic acid. THC acts as a substitute ligand to the 7TM receptor site of AEA. THC would deregulate the physiological function of ...
DOPamine Hydrochloride and 5% Dextrose Injection, USP
DOPamine Hydrochloride and 5% Dextrose Injection, USP

... Dopamine produces positive chronotropic and inotropic effects on the myocardium, resulting in increased heart rate and cardiac contractility. This is accomplished directly by exerting an agonist action on beta-adrenoceptors and indirectly by causing release of norepinephrine from storage sites in sy ...
Nardil - Pfizer
Nardil - Pfizer

... NARDIL has been found to be effective in depressed patients clinically characterized as “atypical,” “nonendogenous,” or “neurotic.” These patients often have mixed anxiety and depression and phobic or hypochondriacal features. There is less conclusive evidence of its usefulness with severely depress ...
Drug Metabolism Biotransformation: the process whereby lipid
Drug Metabolism Biotransformation: the process whereby lipid

... P450s are a major family of enzymes that catalyze oxidation reactions Often referred to as Microsomal Mixed Function Oxidases because of the splitting of oxygen that occurs in the reaction. NADPH + O2 + H+ + Drug Æ NADP + + H2O + Drug-OH The ability to bind and utilize oxygen as a cosubstrate in the ...
АНАЛГЕЗИВНІ ЗАСОБИ
АНАЛГЕЗИВНІ ЗАСОБИ

... • Acts longer than morphine (approximately 6 hours) • Analgesic activity is higher than of morphine, that’s why it’s used in doses of 0,3-0,6 mg • In case of breathing depression, which it causes, naloxon is less effective since buprenorphine is slowly released from the connection with mu-receptors ...
It is not known whether norfloxacin is excreted in human milk
It is not known whether norfloxacin is excreted in human milk

... ...
LENITIN
LENITIN

... Such manifestations of withdrawal, especially the more serious ones, are more common in patients who have received excessive doses over a prolonged period. However, withdrawal symptoms have been reported following abrupt discontinuation of benzodiazepines taken continuously at therapeutic levels. Ac ...
extractives - WordPress.com
extractives - WordPress.com

... * When water alone is employed as the menstruum, alcohol is frequently added to the extractive or to the final preparation as an antimicrobial preservative. 2- Hydroalcoholic mixtures are the most versatile and the most widely employed menstrua. They combine the solvent effects of both water and alc ...
Synthetic cannabinoid case study – various brands | Male
Synthetic cannabinoid case study – various brands | Male

... The use of drugs is widespread in our society and includes not just NPS and illegal substances but alcohol, caffeine and medicines, with each normally taken to achieve a desired effect. People take legal and illegal drugs for many, often similar reasons, including: relaxation, addiction, insomnia, p ...
PRINCIPLES OF PHARMACOLOGY
PRINCIPLES OF PHARMACOLOGY

... called bound drug, and those unbound to protein are called free drug. Only the unbound drugs can diffuse through the capillary wall, produce its systemic effects, be metabolized and be excreted. Bound drugs lose pharmacological activity momentarily, and act as a drug reservoir. Having saturation ...
drug approval process for the treatment of alzheimer`s disease
drug approval process for the treatment of alzheimer`s disease

... volunteers. These trials typically consist of single doses given at one time, under carefully monitored conditions. This testing starts the process of identifying common side effects, as well as finding out how high the dosages can be before adverse side effects occur. Phase 1 studies generally tak ...
Selective Suppression of Cocaine- versus Food
Selective Suppression of Cocaine- versus Food

... al., 2001), and similar findings have been reported in other clinical studies (for review, see Grabowski et al., 2004). Other advantages of amphetamine include its high oral bioavailability, relatively long duration of action, and long-standing clinical availability for the treatment of other disord ...
Routes of drug administration
Routes of drug administration

... involves administration of the drug dose just under the skin. ...
Concurrent Disorders - Saskatoon Health Region
Concurrent Disorders - Saskatoon Health Region

... Data from numerous studies indicate that the presence of comorbid mental illnesses and substance use disorders is a common occurrence. The NIMH’s Epidemiological Catchment Area study conducted within the USA’s general population in the early 1980s revealed that 45% of individuals with an alcohol use ...
The use of benzodiazepines within the Traveller community
The use of benzodiazepines within the Traveller community

... professionals need to consider, ‘the setting of precise indications and prescriptions for the shortest possible period of time.’6 These findings show that this is clearly not being adhered to. Table 1 below highlights the remainder of the responses. Knowledge of general practitioners who prescribe l ...
Illicit Internet availability of drugs subject to recall and patient safety
Illicit Internet availability of drugs subject to recall and patient safety

... The most serious type of recall generally involves situations where there is a reasonable probability that continued use will cause serious adverse health consequences or even death. In most developed countries, these events are categorized as ‘‘Class I’’ recalls and can result in the removal of a s ...
Clinical Challenges when using Pharmacolgo
Clinical Challenges when using Pharmacolgo

... Physician awareness and knowledge Integration with psychosocial treatment Optimal duration of treatment unknown ...
Anti-inflammatory Drugs Lecture Notes Page
Anti-inflammatory Drugs Lecture Notes Page

... – Patients need to rinse mouth after MDI ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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