Appendix A: Glossary
... phase 2 study These studies include more participants (about 100-300) who have the disease or condition that the experimental medication could potentially treat. In Phase 2 studies, researchers seek to gather further safety data and preliminary evidence of the medication’s effects (efficacy). If the ...
... phase 2 study These studies include more participants (about 100-300) who have the disease or condition that the experimental medication could potentially treat. In Phase 2 studies, researchers seek to gather further safety data and preliminary evidence of the medication’s effects (efficacy). If the ...
Adverse Drug Interactions In Dental Practice
... to epinephrine. By blocking vasodilating β2 receptors in the blood vessels of skeletal muscle and other tissues, propranolol causes epinephrine to act vascularly as a pure α-adrenergic stimulant.17-19 Peripheral resistance, which normally falls after moderate doses of epinephrine are administered, r ...
... to epinephrine. By blocking vasodilating β2 receptors in the blood vessels of skeletal muscle and other tissues, propranolol causes epinephrine to act vascularly as a pure α-adrenergic stimulant.17-19 Peripheral resistance, which normally falls after moderate doses of epinephrine are administered, r ...
Agents to Treat Gastric Acidity and Gastroesophageal Reflux (GERD)
... Omeprazole (Prilosec) Omeprazole/sodium bicarbonate (Zegerid) ...
... Omeprazole (Prilosec) Omeprazole/sodium bicarbonate (Zegerid) ...
increased risk of local anesthetic toxicity
... Classification of vasoconstrictor • These drugs can be classified on the basis of mode of action , into the following three categories : • 1- Direct acting drugs : these drugs stimulate or exert their action directly on the adrenergic receptors , for example epinephrine , nor epinephrine , levonord ...
... Classification of vasoconstrictor • These drugs can be classified on the basis of mode of action , into the following three categories : • 1- Direct acting drugs : these drugs stimulate or exert their action directly on the adrenergic receptors , for example epinephrine , nor epinephrine , levonord ...
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
... in internal body temperature to levels that are above normal. In moderation, fever aids in recovery ...
... in internal body temperature to levels that are above normal. In moderation, fever aids in recovery ...
Inhibitors of Microbial Protein Synthesis
... erythromycin) (second line drugs) to treat Strep. and Staph. infections e.g. tonsillitis in patients with penicillin allergy Considered 2nd line therapy to PNC’s for Rx of dental infections (never 1st line because they are static; resistance develops easily to them, less effective than PNC’s in orod ...
... erythromycin) (second line drugs) to treat Strep. and Staph. infections e.g. tonsillitis in patients with penicillin allergy Considered 2nd line therapy to PNC’s for Rx of dental infections (never 1st line because they are static; resistance develops easily to them, less effective than PNC’s in orod ...
chronopharmacology - International Research Journal of Pharmacy
... are controlled by the following systems of the body. Hence it is important to know the circadian rhythms in these systems and their effect on drug action. Urinary system- The urinary system which plays a pivotal role in the elimination of a drug has many instances of circadian rhythms altering eithe ...
... are controlled by the following systems of the body. Hence it is important to know the circadian rhythms in these systems and their effect on drug action. Urinary system- The urinary system which plays a pivotal role in the elimination of a drug has many instances of circadian rhythms altering eithe ...
Mechanism of Action
... of neurological disease In some subgroups, heredity Single gene defects, usually of an autosomal dominant nature involving genes coding voltage-gated ion channels or GABAA receptors has proved to be a predominant factor. This abnormal electrical activity may result in a variety of events, including ...
... of neurological disease In some subgroups, heredity Single gene defects, usually of an autosomal dominant nature involving genes coding voltage-gated ion channels or GABAA receptors has proved to be a predominant factor. This abnormal electrical activity may result in a variety of events, including ...
Prolonged unconsciousness after anaesthesia
... number of factors, as outlined in Table 1. With so many variables, it is not surprising that administration of an ideal dose to one patient can have a very different effect on an apparently similar patient. Benzodiazepines Benzodiazepines are used for anxiolysis and pre-medication; co-induction faci ...
... number of factors, as outlined in Table 1. With so many variables, it is not surprising that administration of an ideal dose to one patient can have a very different effect on an apparently similar patient. Benzodiazepines Benzodiazepines are used for anxiolysis and pre-medication; co-induction faci ...
Gout - KSUMSC
... uric acid level below the saturation point (<6 mg/dL), thus preventing the deposition of urate crystals. This can be accomplished by: 1.interfering with uric acid synthesis with allopurinol 2.increasing uric acid excretion with probenecid or sulfinpyrazone 3.inhibiting leukocyte entry into the affec ...
... uric acid level below the saturation point (<6 mg/dL), thus preventing the deposition of urate crystals. This can be accomplished by: 1.interfering with uric acid synthesis with allopurinol 2.increasing uric acid excretion with probenecid or sulfinpyrazone 3.inhibiting leukocyte entry into the affec ...
Fungal Infections
... During the 1990s use of ketoconazole diminished because of the release of the triazoles-fluconazole and itraconazole (2002voriconazole). ...
... During the 1990s use of ketoconazole diminished because of the release of the triazoles-fluconazole and itraconazole (2002voriconazole). ...
Your Medication Reference Guide
... dizziness, drowsiness, dry mouth, EKG/EEG changes, Extrapyramidal Symptoms (EPS) inability to sit still, low blood pressure, sedation, altered heart rate, Tardive dyskinesia - repetitive movement of tongue/ mouth or any muscle group - Seek immediate medical attention if you experience fever, rigidit ...
... dizziness, drowsiness, dry mouth, EKG/EEG changes, Extrapyramidal Symptoms (EPS) inability to sit still, low blood pressure, sedation, altered heart rate, Tardive dyskinesia - repetitive movement of tongue/ mouth or any muscle group - Seek immediate medical attention if you experience fever, rigidit ...
Tricyclic Antidepressants
... 16, 98%. After changing patient into gown, the nurse yells out that the patient has collapsed. You go in to find the patient now with agonal respirations and in profound coma. ...
... 16, 98%. After changing patient into gown, the nurse yells out that the patient has collapsed. You go in to find the patient now with agonal respirations and in profound coma. ...
Treatment of Urinary Incontinence in women
... Staskin D, Trospium chloride has no effect on memory testing and is assay undetectable in the central nervous system of older patients with overactive bladder. Int J Clin Pract. 2010 Aug;64(9):1294-300. Epub 2010 Jun 17 ...
... Staskin D, Trospium chloride has no effect on memory testing and is assay undetectable in the central nervous system of older patients with overactive bladder. Int J Clin Pract. 2010 Aug;64(9):1294-300. Epub 2010 Jun 17 ...
Phase I Issues for Novel TB Drugs
... – Age, race, gender, renal impairment and/or hepatic impairment ...
... – Age, race, gender, renal impairment and/or hepatic impairment ...
EFFECTS OF SYMPATHOMIMETICS ON CARDIOVASCULAR
... Force & rate of contraction cardiac work O2 consumption due to bradycardia Anti-arrhythmic effects:excitability, automaticity & conductivity (due to its sympathetic blocking + quinidine-like actions) ...
... Force & rate of contraction cardiac work O2 consumption due to bradycardia Anti-arrhythmic effects:excitability, automaticity & conductivity (due to its sympathetic blocking + quinidine-like actions) ...
Neurology Clerkship Emergencies Core Knowledge
... dopamine within the central nervous system. Dopamine’s effects are usually opposed by those of acetylcholine. Therefore, Parkinson’s disease could be viewed as being either a relative dopamine deficiency or a relative excess of acetylcholine activity. In fact, anticholinergic agents are more effecti ...
... dopamine within the central nervous system. Dopamine’s effects are usually opposed by those of acetylcholine. Therefore, Parkinson’s disease could be viewed as being either a relative dopamine deficiency or a relative excess of acetylcholine activity. In fact, anticholinergic agents are more effecti ...
Antibioticss
... are present prior to operation • Wounds associated with old trauma, an abscess, or a perforated viscus. • Infection rate greater than 27% ...
... are present prior to operation • Wounds associated with old trauma, an abscess, or a perforated viscus. • Infection rate greater than 27% ...
HTN - Ronna
... • Worsen decompensated CHF • SSS, first degree heart block are contraindications • Mask symptoms of hypoglycemia; prolonged recovery from hypoglycemia • Rebound hypertension ...
... • Worsen decompensated CHF • SSS, first degree heart block are contraindications • Mask symptoms of hypoglycemia; prolonged recovery from hypoglycemia • Rebound hypertension ...
Strattera (atomoxetine)
... Some patients taking normal dosages of Strattera may develop mild elevation of blood pressure (hypertension). At higher dosages, the incidence of Strattera-induced hypertension may be greater. The increase in blood pressure is usually modest, and very few patients have to discontinue Strattera becau ...
... Some patients taking normal dosages of Strattera may develop mild elevation of blood pressure (hypertension). At higher dosages, the incidence of Strattera-induced hypertension may be greater. The increase in blood pressure is usually modest, and very few patients have to discontinue Strattera becau ...
Lesson 2 Medical and Pharmacy Terminology
... drug products that minimizes microrganism contamination ...
... drug products that minimizes microrganism contamination ...
New therapeutic targets for ACE inhibitors and angiotensin receptor
... II generation. It was proved that there are other enzymes beside the ACE, which are able to competitively catalyze the reaction of the ANG I to ANG II conversion, such as chymase, catepsin D and G, tonin and the CAGE (chymostatin-sensitive angiotensin II – generating enzyme). Chymase, both in the my ...
... II generation. It was proved that there are other enzymes beside the ACE, which are able to competitively catalyze the reaction of the ANG I to ANG II conversion, such as chymase, catepsin D and G, tonin and the CAGE (chymostatin-sensitive angiotensin II – generating enzyme). Chymase, both in the my ...
International Pain Policy Fellowship: Improving Opioid
... Governments to promote access to and rational use of narcotic drugs and psychotropic substances, to adopt measures against unlawful medical practice and to ensure that domestic distribution channels are adequately controlled, and its recommendation 40, in which the Board requested Governments of cou ...
... Governments to promote access to and rational use of narcotic drugs and psychotropic substances, to adopt measures against unlawful medical practice and to ensure that domestic distribution channels are adequately controlled, and its recommendation 40, in which the Board requested Governments of cou ...
Toward a Drug-Free University
... federal, state, and local regulations regarding substance abuse on campus. In order to comply with the law, the Drug and Alcohol Abuse Educational Notification must, at a minimum, include the following: (a) The annual distribution in writing to each employee, and to each student who is taking one or ...
... federal, state, and local regulations regarding substance abuse on campus. In order to comply with the law, the Drug and Alcohol Abuse Educational Notification must, at a minimum, include the following: (a) The annual distribution in writing to each employee, and to each student who is taking one or ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.