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The ICD-10 Classification of Mental and Behavioural Disorders
The ICD-10 Classification of Mental and Behavioural Disorders

... A psychotic disorder occurring during or immediately after drug use (usually within 48 hours) should be recorded here provided that it is not a manifestation of drugwithdrawal state with delirium (see F1x.4) or of late onset. Late-onset psychotic disorders (with onset more than 2 weeks after substa ...
valium - Roche Canada
valium - Roche Canada

... Geriatrics: Elderly and debilitated patients or those with organic brain disorders have been found to be prone to central nervous system depression following even low doses. For these patients it is recommended that the dosage be limited to the smallest, effective amount with incremental increases m ...
India`s Marketing Regulations of Drugs
India`s Marketing Regulations of Drugs

... combination is being done for the first time, and a claim is being made, and/or the combination is likely to result in a significant interaction of a pharmacodynamic or pharmacokinetic nature, then it is treated in the same way as any other new drug. The period to take approval for a new drug is not ...
Marijuana and Your Lungs
Marijuana and Your Lungs

... • THC is absorbed by fatty tissue and for less frequent users THC can be traced in the body by a simple urine test for several days • For chronic or heavy smokers, THC can be traced in the body for up to several weeks ...
Antimycobacterials
Antimycobacterials

... the drug is used alone. High-level resistance is associated with mutation of katG gene that codes for a enzyme KatG involved in the bioactivation of isoniazid. Low-level resistance occurs via deletions in genes that encode the "target enzymes". INH is completely absorbed orally and penetrates all bo ...
What is an alcohol?
What is an alcohol?

... strong. May also have cognitive benefits but this is problematic because the effects of alcohol on the central nervous system are extremely complex, in part because alcohol interacts with many different neurotransmitter systems, and also because the effects on these systems may be dose-dependent and ...
Brain Structures
Brain Structures

Physical and Chemical Methods of Disinfection and Sterilization
Physical and Chemical Methods of Disinfection and Sterilization

Medicines are classified based on how they work in your body.
Medicines are classified based on how they work in your body.

... • Antibiotics are a class of drug that destroy disease causing microorganisms, called bacteria. • Antibiotics work by either killing bacteria or preventing the bacteria from reproducing. • Antibiotics can cause nausea, stomach pain, allergic reactions, and they can lose their effectiveness. • Bacter ...
Signs and Symptoms of PTSD and TBI in Veterans
Signs and Symptoms of PTSD and TBI in Veterans

... • Tearing of the frontal (front) and temporal (on the side) lobes or blood vessels of the brain • Force of the blow causes the brain to rotate across the hard ridges of the skull, causing the tears ...
diuretics
diuretics

... A 70 year old man is admitted with a history of heart failure and acute left ventricular myocardial infarction. He has severe pulmonary edema. Which of the following drugs is LEAST likely to prove useful in the treatment of acute pulmonary edema. A. Bumetanide ...
Chapter 2 - VU Research Portal
Chapter 2 - VU Research Portal

... selectivity. Ultimately, this understanding will lead to more efficient drug discovery and hit optimization. The studies in this thesis involve computational approaches that are strongly supported by experimental data, including dedicated synthesis of interesting new ligands and their pharmacologica ...
Drug Testing and Product Training
Drug Testing and Product Training

... Suboxone in an effort to dissuade patients from injecting the tablets. False positive for oxycodone ...
Selective Serotonin Reuptake Inhibitor- Induced
Selective Serotonin Reuptake Inhibitor- Induced

... larly prone to symptom flare up with infectious triggers. These exacerbations are possibly due to immune system activation as evidenced by prolonged streptococcal antibody elevations.6 Potential mechanisms by which autoantibodies could cause clinical manifestations in PANDAS include direct stimulati ...
Cancer Treatment Drugs
Cancer Treatment Drugs

... The model for monoclonal antibody directed against a surface receptor target is also clinically exploited in the treatment of non Hodgkin lymphoproliferative disorders with the anti-CD20 antibody, rituximab, and the treatment of colorectal cancer with the EGFR monoclonal antibody cetuximab. In gener ...
Investing in Biotech - Cy Lynch
Investing in Biotech - Cy Lynch

... 2. Those close to profitability with growing sales from drugs on the market or potential big sellers in late-stage clinical trials 3. The rest, just having products still in the discovery or clinical stages ...
Hormone Receptors on the Plasma Membrane
Hormone Receptors on the Plasma Membrane

... • receptors that are closely linked to tyrosine kinases • receptors with guanylyl cyclase activity • receptors that serve as transporters ...
Therapy of hypertension
Therapy of hypertension

... creatinine) one week after treatment and then every 3 months. 3-Frequent monitoring of serum K+. 4-Avoid use with K+ sparing diuretics to avoid severe hyperkalemia. 5-Mention other contraindications……. ...
Présentation PowerPoint - International Dose
Présentation PowerPoint - International Dose

... Identify reasonable, response-guided titration steps, and the interval at which they should be taken, again with appropriate adjustments for patient characteristics. These steps would be based either on the shape of the typical individual's dose-effect curves (for both desirable and undesirable effe ...
Antiseizure Drugs
Antiseizure Drugs

... without loss of consciousness (the symptom of each seizure type is often an index of the site of brain dysfunction) Complex partial seizures (psychomotor, temporal lobe) - Stereotyped purposive movements and bizarre behavior accompanied ...
Treatment of Bronchial Asthma in Japan
Treatment of Bronchial Asthma in Japan

... Children tend to respond better than adults and some Japanese pediatricians feel disodium cromoglycate is the first choice drug in children's asthma. Perennial asthmatics without definable allergens may also respond. Exercise-induced asthma can often be prevented by therapy with disodium cromoglycat ...
A novel signal detection algorithm for identifying hidden drug
A novel signal detection algorithm for identifying hidden drug

... DDIs are suspected, sample sizes and cohort biases limit the ability to discovery rare adverse effects.3 Some DDIs can be predicted through careful evaluation of molecular targets and metabolizing enzymes, such as when two drugs are both metabolized by the same enzyme (eg, CYP3A4), resulting in unex ...
13. Local Anesthetics III
13. Local Anesthetics III

... 1. Effect of pH : local anesthetics are basic drugs. The charged (cationic) form binds to receptor site, uncharged form penetrates membrane, efficacy of drug can be changed by altering extracellular or intracellular pH 2. Effect of protein binding: increased binding increases duration of action 3. E ...
Prescribing Information
Prescribing Information

... 2.1 General Instruction for Use The recommended starting dose is 10 mg administered orally once daily without regard to meals. Dosage should then be increased to 20 mg/day, as tolerated, because higher doses demonstrated better treatment effects in trials conducted in the United States. The efficacy ...
BEERS List, An Analysis
BEERS List, An Analysis

... RATIONALE ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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