Rythmodan - Sanofi Canada
... The concomitant use of RYTHMODAN® with other Class I antiarrhythmic agent and/or beta adrenergic blockers should be reserved for patients with life-threatening arrhythmias who are demonstrably unresponsive to single agent antiarrhythmic therapy. Such use may produce serious negative inotropic effect ...
... The concomitant use of RYTHMODAN® with other Class I antiarrhythmic agent and/or beta adrenergic blockers should be reserved for patients with life-threatening arrhythmias who are demonstrably unresponsive to single agent antiarrhythmic therapy. Such use may produce serious negative inotropic effect ...
Prozac/Prozac Weekly/Sarafem (fluoxetine)
... The combination of psychotherapy and antidepressants is very effective in treating moderate to severe depression. The medications improve mood, sleep, energy, and appetite while therapy strengthens coping skills, deals with possible underlying issues, and improves thought patterns and behavior. In g ...
... The combination of psychotherapy and antidepressants is very effective in treating moderate to severe depression. The medications improve mood, sleep, energy, and appetite while therapy strengthens coping skills, deals with possible underlying issues, and improves thought patterns and behavior. In g ...
ION CHANNELS AND DRUG DEVELOPMENT
... Finally, during the last decade the focus is on modulation of the K+ channels. Currently, the therapeutic use of K+ channel modulators is scarce, mainly as vasodilators and antihypertensive agents, however the fast growing field of research is promising a development of new therapeutic agents for ca ...
... Finally, during the last decade the focus is on modulation of the K+ channels. Currently, the therapeutic use of K+ channel modulators is scarce, mainly as vasodilators and antihypertensive agents, however the fast growing field of research is promising a development of new therapeutic agents for ca ...
The pharmacological management of anxiety
... Certain tricyclic antidepressants (TCAs) – clomipramine, imipramine, lofepramine and amitriptyline – are efficacious in some anxiety disorders (Table 2).1 They are, however, associated with a greater burden of adverse reactions such as anticholinergic effects, hypotension, sedation and weight gain. ...
... Certain tricyclic antidepressants (TCAs) – clomipramine, imipramine, lofepramine and amitriptyline – are efficacious in some anxiety disorders (Table 2).1 They are, however, associated with a greater burden of adverse reactions such as anticholinergic effects, hypotension, sedation and weight gain. ...
Drug use in renal and hepatic disorders.
... ECF ( ascites, edema) & ↓↓ muscle mass. •↓↓ plasma protein binding due to impaired albumin production or drug displacement from accumulated substance normally cleared by the liver •↑ Bio avail through ↓↓ first pass metabolism •↓↓ Bioavailability due to malabsorption of fats in cholestatic liver dise ...
... ECF ( ascites, edema) & ↓↓ muscle mass. •↓↓ plasma protein binding due to impaired albumin production or drug displacement from accumulated substance normally cleared by the liver •↑ Bio avail through ↓↓ first pass metabolism •↓↓ Bioavailability due to malabsorption of fats in cholestatic liver dise ...
File
... Age-related (old age) or disease-related changes in liver or kidney disease can cause: Drug accumulation and thus toxicity. Older patients are often prescribed lower doses of medication. If patients are on multiple potent prescription drugs, there is a risk of a drug-drug interaction. Drug acc ...
... Age-related (old age) or disease-related changes in liver or kidney disease can cause: Drug accumulation and thus toxicity. Older patients are often prescribed lower doses of medication. If patients are on multiple potent prescription drugs, there is a risk of a drug-drug interaction. Drug acc ...
Drug Elimination
... ECF ( ascites, edema) & muscle mass. • plasma protein binding due to impaired albumin production or drug displacement from accumulated substance normally cleared by the liver • Bio avail through first pass metabolism • Bioavailability due to malabsorption of fats in cholestatic liver dise ...
... ECF ( ascites, edema) & muscle mass. • plasma protein binding due to impaired albumin production or drug displacement from accumulated substance normally cleared by the liver • Bio avail through first pass metabolism • Bioavailability due to malabsorption of fats in cholestatic liver dise ...
NEW ZEALAND DATA SHEET CLOZARIL® (clozapine) 25mgand
... Clozaril® can cause agranulocytosis. Its use should be limited to patients: with schizophrenia who are non-responsive to or intolerant of classical antipsychotic agents, or with schizophrenia or schizoaffective disorder who are at risk of recurrent suicidal behaviour (see Indications), who have ...
... Clozaril® can cause agranulocytosis. Its use should be limited to patients: with schizophrenia who are non-responsive to or intolerant of classical antipsychotic agents, or with schizophrenia or schizoaffective disorder who are at risk of recurrent suicidal behaviour (see Indications), who have ...
Herbal Medication Pitfalls Question “Natural Product” or Drug
... medicines available. However, one must be aware of the power of herbs to heal and, if misused, to cause imbalance. Herbs produce no side effects when used in the amounts required to effect a cure. Negative effects occur only when one fails to observe the cautions that herbalists have recognized afte ...
... medicines available. However, one must be aware of the power of herbs to heal and, if misused, to cause imbalance. Herbs produce no side effects when used in the amounts required to effect a cure. Negative effects occur only when one fails to observe the cautions that herbalists have recognized afte ...
Sylenol - Taj Drug
... DRUG CLASS AND MECHANISM: Acetaminophen belongs to a class of drugs called analgesics (pain relievers) and antipyretics (fever reducers). The exact mechanism of action of acetaminophen is not known. Acetaminophen relieves pain by elevating the pain threshold, that is, by requiring a greater amount o ...
... DRUG CLASS AND MECHANISM: Acetaminophen belongs to a class of drugs called analgesics (pain relievers) and antipyretics (fever reducers). The exact mechanism of action of acetaminophen is not known. Acetaminophen relieves pain by elevating the pain threshold, that is, by requiring a greater amount o ...
SCID-I (for DSM-IV-TR) Alcohol Abuse (JAN 2010) Substance Use
... 1 MONTH IN THE PAST. Number of months prior to interview when last had some problems with drug ...
... 1 MONTH IN THE PAST. Number of months prior to interview when last had some problems with drug ...
An Artificial Neural Network Model of the Milk-Ejection Reflex in the Sheep
... 3.2.2. Moderate stimulus amplitudes. As the stimulus amplitude increases the frequency of firing increases and excitatory synaptic weight takes on higher values. At the same time the frequency of inhibitory neurons increases and a point is reached where sustained network activity is observed but neu ...
... 3.2.2. Moderate stimulus amplitudes. As the stimulus amplitude increases the frequency of firing increases and excitatory synaptic weight takes on higher values. At the same time the frequency of inhibitory neurons increases and a point is reached where sustained network activity is observed but neu ...
NonCognitive Behavioral/neuropsychiatric and Functional
... Methadone can be helpful, but should be prescribed by clinicians with expertise with its use or in closely monitored settings because of unpredictable pharmokinetics in older persons Fentanyl can be difficult to titrate…don’t start with it…don’t use in opioid-naïve pts ...
... Methadone can be helpful, but should be prescribed by clinicians with expertise with its use or in closely monitored settings because of unpredictable pharmokinetics in older persons Fentanyl can be difficult to titrate…don’t start with it…don’t use in opioid-naïve pts ...
Local anesthetics
... Effect of lipophilicity ANESTHETIC POTENCY Lipid solubility appears to be the primary determinant of intrinsic anesthetic potency. Chemical compounds which are highly lipophilic tend to penetrate the nerve membrane more easily, such that less molecules are required for conduction blockade resulti ...
... Effect of lipophilicity ANESTHETIC POTENCY Lipid solubility appears to be the primary determinant of intrinsic anesthetic potency. Chemical compounds which are highly lipophilic tend to penetrate the nerve membrane more easily, such that less molecules are required for conduction blockade resulti ...
A neurocognitive model for understanding treatment action in
... of antidepressant drugs. In animal models, neurogenesis is stimulated by antidepressant treatment, and some of the behavioural effects of these treatments are blocked by ablating neurogenesis [5]. The maturation of new cells takes several weeks, in line with the delay in treatment response [6]. One ...
... of antidepressant drugs. In animal models, neurogenesis is stimulated by antidepressant treatment, and some of the behavioural effects of these treatments are blocked by ablating neurogenesis [5]. The maturation of new cells takes several weeks, in line with the delay in treatment response [6]. One ...
ABM Clinical Protocol #9: Use of Galactogogues in Initiating or
... oats, dandelion, millet, seaweed, anise, basil, blessed thistle, fennel seeds, marshmallow, and many others. Although beer is used in some cultures, alcohol may actually reduce milk production. A barley component of beer (even nonalcoholic beer) can increase prolactin secretion, but there are ‘‘no s ...
... oats, dandelion, millet, seaweed, anise, basil, blessed thistle, fennel seeds, marshmallow, and many others. Although beer is used in some cultures, alcohol may actually reduce milk production. A barley component of beer (even nonalcoholic beer) can increase prolactin secretion, but there are ‘‘no s ...
Review of Opioids and Treatment of Opioid Dependence Medical Director, PCSS-O
... Types of opioids and their effects Pharmacology of opioids Treatment modalities Pregnancy and other special groups ...
... Types of opioids and their effects Pharmacology of opioids Treatment modalities Pregnancy and other special groups ...
Herbal Medicine for the Family Physician
... Uses: Nervous tension (anxiety), stress and agitation, insomnia Kava pyrones have central muscle-relaxing, anticonvulsive, hypnotic/sedative effects by interaction with ion channels and GABA sites Possibly unsafe-studies show safe use for up to six months but 68 documented liver failures even with s ...
... Uses: Nervous tension (anxiety), stress and agitation, insomnia Kava pyrones have central muscle-relaxing, anticonvulsive, hypnotic/sedative effects by interaction with ion channels and GABA sites Possibly unsafe-studies show safe use for up to six months but 68 documented liver failures even with s ...
Protocol - Medicines Management
... To review the child as they move towards the age at which they will be discharged from the Paediatric pathway to determine on-going need: o To facilitate the cessation of drug therapy at this stage if clinically possible This document will be reviewed in the light of new or emerging evidence or by O ...
... To review the child as they move towards the age at which they will be discharged from the Paediatric pathway to determine on-going need: o To facilitate the cessation of drug therapy at this stage if clinically possible This document will be reviewed in the light of new or emerging evidence or by O ...
Doctor I feeling Dizzy - ACM
... C. Dysequilibrium Sensation of losing one’s balance without a feeling of illusionary movement Typically patients do not report symptoms sitting or lying, but notice unsteadiness standing or walking ...
... C. Dysequilibrium Sensation of losing one’s balance without a feeling of illusionary movement Typically patients do not report symptoms sitting or lying, but notice unsteadiness standing or walking ...
mAChR AntagWEB07
... • Five different mAChR in humans (all in CNS) • M1- in sympathetic ganglia (and adrenal medulla), activated by McN-A-343, blocked by pirenzepine • M2- cardiac mAChR; can contribute to contraction of some smooth muscles; a presynaptic receptor on some nerve terminals • M3- mediates contraction of smo ...
... • Five different mAChR in humans (all in CNS) • M1- in sympathetic ganglia (and adrenal medulla), activated by McN-A-343, blocked by pirenzepine • M2- cardiac mAChR; can contribute to contraction of some smooth muscles; a presynaptic receptor on some nerve terminals • M3- mediates contraction of smo ...
Psilocybin links binocular rivalry switch rate to attention and
... ketanserin blocked the majority of psilocybin’s “positive” psychosis-like hallucinogenic symptoms. However, ketanserin had no influence on either the psilocybin-induced slowing of binocular rivalry or the drug’s “negative-type symptoms” associated with reduced arousal and vigilance. Conclusions Toge ...
... ketanserin blocked the majority of psilocybin’s “positive” psychosis-like hallucinogenic symptoms. However, ketanserin had no influence on either the psilocybin-induced slowing of binocular rivalry or the drug’s “negative-type symptoms” associated with reduced arousal and vigilance. Conclusions Toge ...
Oral Drug Therapy Guidelines in Surgical Patients
... when they are likely to be restarted. If a patient requires emergency surgery then the surgical team should liaise with the anaesthetist to discuss which drugs should and should not be stopped prior to surgery and when to restart any discontinued drugs. A patient may be ‘Nil-by-mouth’ for several re ...
... when they are likely to be restarted. If a patient requires emergency surgery then the surgical team should liaise with the anaesthetist to discuss which drugs should and should not be stopped prior to surgery and when to restart any discontinued drugs. A patient may be ‘Nil-by-mouth’ for several re ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.