Anti-cancer and neuroprotective IP6
... cross the blood-brain barrier, a relatively impermeable border crossing that allows only select agents across in order to protect the brain. Whether it can do this or not does not prevent IP6 from chelating iron elsewhere in the body and performing its other anti-cancer functions. ...
... cross the blood-brain barrier, a relatively impermeable border crossing that allows only select agents across in order to protect the brain. Whether it can do this or not does not prevent IP6 from chelating iron elsewhere in the body and performing its other anti-cancer functions. ...
Nasal Drug Delivery in EMS
... Three quarters wanted to continue use. One-quarter (that did not have good experience) had higher opiate baseline needs. ...
... Three quarters wanted to continue use. One-quarter (that did not have good experience) had higher opiate baseline needs. ...
Original Article Inhibitory effects of 19 antiprotozoal drugs and
... mice infected with Babesia microti. The aims of the present study were to find a preferable method for drug screening and to re-evaluate the activity of several drugs against B. microti. Methodology: The activity of 19 drugs on B. microti-infected BALB/c mice was evaluated. The study was built on Pe ...
... mice infected with Babesia microti. The aims of the present study were to find a preferable method for drug screening and to re-evaluate the activity of several drugs against B. microti. Methodology: The activity of 19 drugs on B. microti-infected BALB/c mice was evaluated. The study was built on Pe ...
Assessment and Treatment of Alcohol Dependence
... of nutritional neglect or diarrhoea/vomiting is common and can require treatment to reverse. Low sodium is less common but can occur due to high fluid intake. Low magnesium is a common finding in alcohol dependence. ...
... of nutritional neglect or diarrhoea/vomiting is common and can require treatment to reverse. Low sodium is less common but can occur due to high fluid intake. Low magnesium is a common finding in alcohol dependence. ...
Drugs - DBDD
... illegal substances (primarily: cannabis) among adolescents and young adults. The ESA 2015 reported an increasing prevalence of use, in particular for cannabis, among 18 to 24 yearolds. Although the current data from the BZgA (DAS) shows a slight decline, the trend has stagnated at this relatively hi ...
... illegal substances (primarily: cannabis) among adolescents and young adults. The ESA 2015 reported an increasing prevalence of use, in particular for cannabis, among 18 to 24 yearolds. Although the current data from the BZgA (DAS) shows a slight decline, the trend has stagnated at this relatively hi ...
Introduction of new drugs and drug regimens for the management of
... MDR TB is not based on randomised clinical trial evidence but rather on expert opinion. For the treatment of even more resistant TB including XDR TB, the best data available is retrospective cohort data. While there is on-going clinical research into a shorter regimen with the current registered dru ...
... MDR TB is not based on randomised clinical trial evidence but rather on expert opinion. For the treatment of even more resistant TB including XDR TB, the best data available is retrospective cohort data. While there is on-going clinical research into a shorter regimen with the current registered dru ...
Synaptic-Type a1b2g2L GABA A Receptors Produce Large
... extracellular GABA (Houston et al., 2012) is several tens of folds lower than the apparent affinity to GABA of synaptic subtypes of GABAA receptors (Li et al., 2006; Picton and Fisher, 2007). Under physiologic conditions, GABAA receptors, including synaptic receptors, are exposed to endogenous modul ...
... extracellular GABA (Houston et al., 2012) is several tens of folds lower than the apparent affinity to GABA of synaptic subtypes of GABAA receptors (Li et al., 2006; Picton and Fisher, 2007). Under physiologic conditions, GABAA receptors, including synaptic receptors, are exposed to endogenous modul ...
EPINEPHRINE - Pfizer Injectables
... Epinephrine should not be administered concomitantly with other sympathomimetic drugs (such as isoproterenol) because of possible additive effects and increased toxicity. Combined effects may induce serious cardiac arrhythmias. They may be administered alternately when the preceding effect of other ...
... Epinephrine should not be administered concomitantly with other sympathomimetic drugs (such as isoproterenol) because of possible additive effects and increased toxicity. Combined effects may induce serious cardiac arrhythmias. They may be administered alternately when the preceding effect of other ...
Management of sodium-channel blocker poisoning: the role of
... The dissociation of the blocking agent from the channel could be related to the rise in Na+ concentration [mass effect], and this would explain the assumed benefits of hypertonic saline solution reported in literature29-31. Electrostatic repulsion has been postulated to explain the reduction in Na+ ...
... The dissociation of the blocking agent from the channel could be related to the rise in Na+ concentration [mass effect], and this would explain the assumed benefits of hypertonic saline solution reported in literature29-31. Electrostatic repulsion has been postulated to explain the reduction in Na+ ...
GHB / GBL leaflet
... ingested recreationally by people. Driving whilst under the influence of GHB and GBL is illegal (and you can still be unfit to drive the day after using). You can get a heavy fine, be disqualified from driving or go to prison. The Sexual Offences Act 2003 states that it is an offence to administer G ...
... ingested recreationally by people. Driving whilst under the influence of GHB and GBL is illegal (and you can still be unfit to drive the day after using). You can get a heavy fine, be disqualified from driving or go to prison. The Sexual Offences Act 2003 states that it is an offence to administer G ...
The Rapid and Chronic Tolerance in Drosophila
... http://www.imsb.ethz.ch/researchgroup/hafene/researchprojects/Drosophila.jpg ...
... http://www.imsb.ethz.ch/researchgroup/hafene/researchprojects/Drosophila.jpg ...
MELATONIN for treatment of sleep onset insomnia and
... least 3 months), to send the GP a Shared Care Agreement Form (Page 1) inviting them to participate in shared care management of the patient. x. To monitor the patient in accordance with the schedule above (see Section 8). xi. To inform the general practitioner of dosage schedule, monitoring measurem ...
... least 3 months), to send the GP a Shared Care Agreement Form (Page 1) inviting them to participate in shared care management of the patient. x. To monitor the patient in accordance with the schedule above (see Section 8). xi. To inform the general practitioner of dosage schedule, monitoring measurem ...
Alcohol Withdrawal Syndrome: Benzodiazepines and Beyond
... undergo adaptive change in an attempt to maintain normal function. Some key changes involve decrease in both brain gamma-amino butyric acid (GABA) levels and GABA-receptor sensitivity [13,14] and activation of glutamate systems [15], which leads to nervous system hyperactivity in the absence of alco ...
... undergo adaptive change in an attempt to maintain normal function. Some key changes involve decrease in both brain gamma-amino butyric acid (GABA) levels and GABA-receptor sensitivity [13,14] and activation of glutamate systems [15], which leads to nervous system hyperactivity in the absence of alco ...
Suitable dosage forms for paediatric medicine
... The dose of API is fixed by using empirically established dosage regimen and the dose combination is sometimes largely used, which is not really convenient. The DF used and the ones to be developed in the future can be classified according to their use by the parents or the children compliance ( ...
... The dose of API is fixed by using empirically established dosage regimen and the dose combination is sometimes largely used, which is not really convenient. The DF used and the ones to be developed in the future can be classified according to their use by the parents or the children compliance ( ...
Summary of RLS treatment recommendations FINAL
... Some degree of augmentation has been reported with the use of all investigated dopaminergic drugs and also for tramadol. In the virtual absence of direct comparative studies, the incidence rate seems highe ...
... Some degree of augmentation has been reported with the use of all investigated dopaminergic drugs and also for tramadol. In the virtual absence of direct comparative studies, the incidence rate seems highe ...
![Saunders [CV][10_2016] - Psychology](http://s1.studyres.com/store/data/004885651_1-d74cbfae24aab82d23a47ef46caa05b1-300x300.png)
Saunders [CV][10_2016] - Psychology
... Shaaban, K.A., Saunders, M.A., Zhang, Y., Tran, T., Elshahawi, S.I., Ponomareva, L.V., Wang, X., Zhang, J., Copley, G.C., Sunkara, M., Kharel, M.K., Morris, A.J., Hower, J.C., Tremblay, M.S., Prendergast, M.A., & Thorson, J.S. Spoxazomicin D and Oxachelin C, potent neuroprotective carboxamides from ...
... Shaaban, K.A., Saunders, M.A., Zhang, Y., Tran, T., Elshahawi, S.I., Ponomareva, L.V., Wang, X., Zhang, J., Copley, G.C., Sunkara, M., Kharel, M.K., Morris, A.J., Hower, J.C., Tremblay, M.S., Prendergast, M.A., & Thorson, J.S. Spoxazomicin D and Oxachelin C, potent neuroprotective carboxamides from ...
... BACKGROUND & OBJECTIVES The drug quality control process is not only important for getting a new drug approved but it is also an important process for ensuring that drugs that have reached the market can be periodically monitored in order to ensure their stability. For that reason the development of ...
ARCI-025-020 Medications and Prohibited Substances
... (g) Local anesthetics which that have a reasonable potential for use as nerve blocking agents (except procaine); and (h) Snake venoms and other biologic substances, which may be used as nerve blocking agents. (3) Class 3 Drugs placed in this class may or may not have an accepted therapeutic use in t ...
... (g) Local anesthetics which that have a reasonable potential for use as nerve blocking agents (except procaine); and (h) Snake venoms and other biologic substances, which may be used as nerve blocking agents. (3) Class 3 Drugs placed in this class may or may not have an accepted therapeutic use in t ...
Age-related differences in reporting of drug
... Spanish Drug-induced Liver Injury Registry occurred in those over age 60, with amoxicillin/clavulanate frequently implicated. Amoxicillin/clavulanate is the most common cause of drug-induced liver injury in many countries, accounting for approximately 10% of cases (Andrade 2005, Chalasani 2008) and ...
... Spanish Drug-induced Liver Injury Registry occurred in those over age 60, with amoxicillin/clavulanate frequently implicated. Amoxicillin/clavulanate is the most common cause of drug-induced liver injury in many countries, accounting for approximately 10% of cases (Andrade 2005, Chalasani 2008) and ...
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... is prepared from the uncontrolled substance naltrexone and retains the structural features of naltrexone that result in u-opioid receptor antagonist activity. This activity likely underlies the effect of samidorphan to block subjective and physiological effects of opioid drugs, as seen in clinical a ...
... is prepared from the uncontrolled substance naltrexone and retains the structural features of naltrexone that result in u-opioid receptor antagonist activity. This activity likely underlies the effect of samidorphan to block subjective and physiological effects of opioid drugs, as seen in clinical a ...
The Effect of Psychopharmacological Agents on Appetite and Eating
... drug inhibits nonepinephrine and blocks alpha-adrenergic receptors, leading to a relative increase in betaadrenergic effect. This would lead to sitmulation of beta-adrenergic receptors in the pancreas, with a subsequent increase in insulin. The insulin would produce hypoglycemia and hunger. Needlema ...
... drug inhibits nonepinephrine and blocks alpha-adrenergic receptors, leading to a relative increase in betaadrenergic effect. This would lead to sitmulation of beta-adrenergic receptors in the pancreas, with a subsequent increase in insulin. The insulin would produce hypoglycemia and hunger. Needlema ...
Signaled drug delivery and transport across the blood
... trigger (e.g. local pH, a specific enzyme) [2]. If the external stimulus is focused at the target site for drug release, it will trigger release of drug from the responsive drugloaded nanoparticles as they are carried by the blood through that region. Sophisticated targeted delivery using magnetic ...
... trigger (e.g. local pH, a specific enzyme) [2]. If the external stimulus is focused at the target site for drug release, it will trigger release of drug from the responsive drugloaded nanoparticles as they are carried by the blood through that region. Sophisticated targeted delivery using magnetic ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.