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Antiarrhythmic therapy in patients with atrial fibrillation
Antiarrhythmic therapy in patients with atrial fibrillation

... with ventricular conduction 1:1. Described percentage of this type of pro-arrhythmic action of flecainide vary from 3.5 to 5.0% (8). In order to reduce the risk of rapid conduction of supraventricular arrhythmia to ventricles, along with propafenone or flecainide there should be administered drugs t ...
Herbal / Drug Interactions PHARM 512: Clinical Applications of Drug
Herbal / Drug Interactions PHARM 512: Clinical Applications of Drug

—  Press Release  — March 12, 2014 American Herbal Pharmacopoeia
— Press Release — March 12, 2014 American Herbal Pharmacopoeia

... Seizures are the characteristic and principal symptom of epilepsy, a chronic progressive disorder that affects approximately 1% of the world’s population and is, in the majority of cases, idiopathic or cryptogenic in nature. Approximately 30% of individuals with epilepsy do not obtain adequate seizu ...
Presentation
Presentation

... Chloroquine and Hydroxychloroquine - effects of Neostigmine may be diminished because of potential for Chloroquine and Hydroxychloroquine to increase symptoms of myasthenia gravis Many drugs have antimuscarinic effects; concomitant use of two or more such drugs can increase side-effects such as dry ...
Effects on upper gastrointestinal motility
Effects on upper gastrointestinal motility

... was found to be statistically equivalent, superior or inferior according to the various studies (Table II). A recent small double-blind trial versus cisapride yielded similar significant therapeutic results with the two drugs (76). Preliminary observations suggest that domperidone may also be effect ...
Complementary and Alternative Medicine Approaches to Migraine
Complementary and Alternative Medicine Approaches to Migraine

How Do Dreams Differ in People With Schizophrenia From Those
How Do Dreams Differ in People With Schizophrenia From Those

... done in a month. Everyday each subject will have a diary and after they wake up they should write down in their diary the dreams they had. Then the Rorschach test should be administered to the subjects to gauge their responses to the images they see. By using this research design, perhaps results wi ...
Suggestion from clinicians
Suggestion from clinicians

... lisinopril, perindopril, ramipril, and imidapril. However, the differences in mortality risk among individual ACE inhibitors were only marginal and might be of limited clinical significance. On the other hand, despite that uncontrolled confounding might still exist, there was a consistent increased ...
Drugs working template
Drugs working template

... 2015]. An important trial in Uganda showed that a dose of 04.mg/kg was as effective as the WHO recommended dose of 0.75 mg/kg [Eziefula, 2014a], and other trials of low dose regimens are in progress. However, as the Cochrane review [Graves, 2015] points out, there is still no direct evidence that ad ...
Extension of agreement on Telmisartan (Micardis
Extension of agreement on Telmisartan (Micardis

... Boehringer Ingelheim, has been approved in over 100 countries around the world including Japan, USA and EU. In Japan, the Micardis® family is manufactured by Nippon Boehringer Ingelheim, distributed by Astellas, and co-promoted by both companies. In Japan, all these drugs are indicated for hypertens ...
Effects of a 5‐HT3 antagonist, ondansetron, on fasting and
Effects of a 5‐HT3 antagonist, ondansetron, on fasting and

... antagonist inhibits the nausea and vomiting associated with chemotherapy. An important side effect in such patients is constipation. This has been exploited therapeutically in irritable bowel syndrome with diarrhoea (IBS-D) patients in whom 5HT3 receptor antagonists improve symptoms, reducing stool ...
Neurologic Effects of Caffeine - Health301Co
Neurologic Effects of Caffeine - Health301Co

... nucleus (extrapyramidal motor system) and the neural structures regulating the sleepwake cycle, the 2 functions that are most sensitive to caffeine. Thus, although caffeine fulfills some of the criteria for drug dependence and shares with amphetamine and cocaine a certain specificity of action on t ...
Vioxx Report.indd - The Physicians Committee
Vioxx Report.indd - The Physicians Committee

... arising from the Human Genome Project. The use of are presented, and the superiority of replacement methgenetically modified research animals, nonphysiologi- ods is reviewed. Finally, the paper makes several recomcal approaches attempting to duplicate human diseases, mendations for improving upon cur ...
TRANSDERMAL PATCHES: A RECENT APPROCH TO NEW DRUG DELIVERY SYSTEM
TRANSDERMAL PATCHES: A RECENT APPROCH TO NEW DRUG DELIVERY SYSTEM

ROMAZICON 1 (flumazenil)
ROMAZICON 1 (flumazenil)

... General Anesthesia in Adults ROMAZICON was studied in four trials in 644 patients who received midazolam as an induction and/or maintenance agent in both balanced and inhalational anesthesia. Midazolam was generally administered in doses ranging from 5 mg to 80 mg, alone and/or in conjunction with m ...
The Transfer of Drugs and Therapeutics Into Human Breast Milk: An
The Transfer of Drugs and Therapeutics Into Human Breast Milk: An

... changes in US Food and Drug Administration (FDA) labeling that are designed to provide useful information to the physician and to outline general ...
Irritable Bowel Syndrome and Antidepressants
Irritable Bowel Syndrome and Antidepressants

... of IBS with anxiety, chronic fatigue syndrome, and fibromyalgia, as well as depression.3,4 The research is sufficiently specific to differentiate a higher frequency of IBS symptoms with panic disorder, generalized anxiety disorder, and major depressive disorder versus social anxiety disorder, specif ...
Tetracyclines
Tetracyclines

... odorless, slightly bitter compounds. They are only slightly soluble in water at pH 7 but they can form soluble sodium salts and hydrochloride. ...
goline
goline

... from driving or engaging in activities where impaired alertness may put themselves or others at risk of serious injury or death (e.g. operating machines) unless patients have overcome such experiences of somnolence. ...
Normal Thermoregulatory Responses to 3-iodothyronamine, Trace Amines and Amphetamine-like Psychostimulants in
Normal Thermoregulatory Responses to 3-iodothyronamine, Trace Amines and Amphetamine-like Psychostimulants in

... this TAAR1 agonist different from other TAAR1 agonists such as endogenous monoamines (e.g., trace amines and common biogenic amines) and exogenous amphetamine-like psychostimulants (e.g., amphetamine and methamphetamine) that are monoamine transporter substrates (Snead et al., 2007; Xie et al., 2007 ...
4: Central nervous system - Gateshead Health NHS Foundation Trust
4: Central nervous system - Gateshead Health NHS Foundation Trust

... Benzodiazepines are indicated for the short-term relief (2-4 weeks only) of anxiety that is severe, disabling or subjecting the individual to unacceptable distress. The use of benzodiazepines benzodiazepines to treat short-term "mild" anxiety is inappropriate and unsuitable. ...
Beta adrenergic influence on oesophageal peristalsis
Beta adrenergic influence on oesophageal peristalsis

... terbutaline from 3-3±0+2 cm/sec to 2-9±0-2 cm/sec (p<005). Prenalterol 1 mg iv was followed by a decrease of peristaltic pressure in the middle oesophagus from 10-2± 1*3 to 7X7±1-1 kPa (p<0.01) and a decrease of peristaltic velocity in upper oesophagus from 3*6±0+2 to 3-3±0*1 cm/sec (p<005) while no ...
PERCUTANEOUS DRUG DELIVERY SYSTEMS FOR IMPROVING ANTIFUNGAL THERAPY EFFECTIVENESS: A REVIEW
PERCUTANEOUS DRUG DELIVERY SYSTEMS FOR IMPROVING ANTIFUNGAL THERAPY EFFECTIVENESS: A REVIEW

... The physicochemical and pharmacokinetic properties of these drugs plus their inherent antifungal potency determine their efficacy, so they are important issues to consider in pre-development stage. FLZ is more polar than other azoles, slightly soluble in water (5 mg/mL at 37ºC), metabolically stable ...
The Effects of Nicotine Conditioned Place Preference in D2 Primed
The Effects of Nicotine Conditioned Place Preference in D2 Primed

... most nations are struggling to reduce because it easily affects communities. One group of people who are at an especially high risk for abusing substances is schizophrenia patients. It has been reported that there are higher rates of substance abuse among schizophrenics compared to the normal popula ...
Serotonin Transporter Occupancy of Five Selective Serotonin
Serotonin Transporter Occupancy of Five Selective Serotonin

... To obtain a measure of the 5-HTT binding potential with region-of-interest data, we used the noninvasive method of Logan et al. (23) implemented within a standard software package (24). This model assumes that there is a region of interest that contains specifically bound radioligand and that there ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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