
Congenital Anomaly of Cochlea: A Case Report
... stage at about sixth week of gestation.In this anomaly only basal turn of cochlea is developed. There is deficient interscalar septum for the distal one & half turn. Thus bony cochlea is restricted to 1.5 turns only. This causes sensorineural hearing loss. The normal cochlea has two and one-half tur ...
... stage at about sixth week of gestation.In this anomaly only basal turn of cochlea is developed. There is deficient interscalar septum for the distal one & half turn. Thus bony cochlea is restricted to 1.5 turns only. This causes sensorineural hearing loss. The normal cochlea has two and one-half tur ...
eaton-peabody laboratory publications
... Sohmer HS, WT Peake, TF Weiss (1971) “Intracochlear Potential Recorded with Micropipets. I. Correlations with Micropipet Location.” J. Acoust. Soc. Amer. 50: 572-586. Weiss TF, WT Peake, HS Sohmer (1971. “Intracochlear Potential Recorded with Micropipets.II. Response, in the Cochlear Scalae to Tones ...
... Sohmer HS, WT Peake, TF Weiss (1971) “Intracochlear Potential Recorded with Micropipets. I. Correlations with Micropipet Location.” J. Acoust. Soc. Amer. 50: 572-586. Weiss TF, WT Peake, HS Sohmer (1971. “Intracochlear Potential Recorded with Micropipets.II. Response, in the Cochlear Scalae to Tones ...
129 - UCSF Physiology
... Figure 1. Distributions of nerve fibers in the cochlea of NT-3 and BDNF heterozygous and homozygous mutant mice at birth. Whole-mounted cochleas from a newborn NT-3 homozygous mutant (A, C) and an NT-3 heterozygous littermate ( B), a BDNF heterozygous mutant ( D), and a BDNF homozygous mutant ( E) s ...
... Figure 1. Distributions of nerve fibers in the cochlea of NT-3 and BDNF heterozygous and homozygous mutant mice at birth. Whole-mounted cochleas from a newborn NT-3 homozygous mutant (A, C) and an NT-3 heterozygous littermate ( B), a BDNF heterozygous mutant ( D), and a BDNF homozygous mutant ( E) s ...
dr-thesis-2016-Sudeep-Mukerji - BORA
... the a 16th Century Italian anatomist and scientist called Hieronymous Fabricius (15331619). He was the first to allude to both an auditory and non-auditory role of the tensor tympani muscle in humans. Since his work, many theories have been created founded on an evolving ability to analyze the compo ...
... the a 16th Century Italian anatomist and scientist called Hieronymous Fabricius (15331619). He was the first to allude to both an auditory and non-auditory role of the tensor tympani muscle in humans. Since his work, many theories have been created founded on an evolving ability to analyze the compo ...
Cochlear implantation step by step
... The implantation centre can provide advice on participation in sports activity, the implant system and specific precautions to take. Manufacturers can also provide useful advice related to special features of their products. ...
... The implantation centre can provide advice on participation in sports activity, the implant system and specific precautions to take. Manufacturers can also provide useful advice related to special features of their products. ...
Cochlear Implant
... A cochlear implant is a device for people with severe-to-profound hearing loss who only receive limited benefit from amplification with hearing aids. A cochlear implant provides direct electrical stimulation to the auditory nerve, bypassing the usual transducer cells that are absent or nonfunctional ...
... A cochlear implant is a device for people with severe-to-profound hearing loss who only receive limited benefit from amplification with hearing aids. A cochlear implant provides direct electrical stimulation to the auditory nerve, bypassing the usual transducer cells that are absent or nonfunctional ...
Embedding of Internal and External Components of Cochlear
... to 75% and localization was improved for all subjects. Subjective reports were very positive and all subjects used the device at all times, with substantial relief from tinnitus. Another pilot study by Hassepass et al.10 (Freiburg, Germany) is collecting outcomes in children with acquired SSD. Three ...
... to 75% and localization was improved for all subjects. Subjective reports were very positive and all subjects used the device at all times, with substantial relief from tinnitus. Another pilot study by Hassepass et al.10 (Freiburg, Germany) is collecting outcomes in children with acquired SSD. Three ...
Effects of Specific Cochlear Pathologies on the Auditory
... simple, affordable, reliable and fast, it does not offer differential information about origins of the hearing impairment. The main goal of this thesis is to quantitatively link specific cochlear pathologies to certain changes in the spectral and temporal characteristics of the auditory system. This ...
... simple, affordable, reliable and fast, it does not offer differential information about origins of the hearing impairment. The main goal of this thesis is to quantitatively link specific cochlear pathologies to certain changes in the spectral and temporal characteristics of the auditory system. This ...
Cochlear Implantation
... During the 1960s there were several objections to human cochlear implantation by many in the basic science community. Essentially, it was believed to be physically impossible for any meaningful hearing to be achieved based on what was known at the time of the physiology and physics of the ear. Objec ...
... During the 1960s there were several objections to human cochlear implantation by many in the basic science community. Essentially, it was believed to be physically impossible for any meaningful hearing to be achieved based on what was known at the time of the physiology and physics of the ear. Objec ...
Bilateral Cochlear Implantation in the United States: Two ears ARE
... cochlear implant user, there will always be someone positioned away from the implanted side, making group conversation more challenging. Localization: Hearing with two ears is essential for humans and animals in identifying the direction of sounds. The ability to localize sounds has obvious safety i ...
... cochlear implant user, there will always be someone positioned away from the implanted side, making group conversation more challenging. Localization: Hearing with two ears is essential for humans and animals in identifying the direction of sounds. The ability to localize sounds has obvious safety i ...
Cochlear implants
... If you think that an implant should be considered, then contact your local ENT consultant or audiology service, to obtain a referral. If you are unsure about whether an implant is the right way forward, it is a good idea to ask for a referral to a Cochlear Implant Centre, because the implant process ...
... If you think that an implant should be considered, then contact your local ENT consultant or audiology service, to obtain a referral. If you are unsure about whether an implant is the right way forward, it is a good idea to ask for a referral to a Cochlear Implant Centre, because the implant process ...
Cochlear Implants for Sensorineural Hearing Loss
... overcome. Within the past 25 years, physicians have been able to offer severely and profoundly deaf patients an opportunity to regain at least partial auditory function through the use of cochlear implants. Whereas hearing aids only amplify sound and deliver it to a damaged sensory system, often res ...
... overcome. Within the past 25 years, physicians have been able to offer severely and profoundly deaf patients an opportunity to regain at least partial auditory function through the use of cochlear implants. Whereas hearing aids only amplify sound and deliver it to a damaged sensory system, often res ...
Importance of cochlear health for implant function
... stimulation. One of the first challenges we face is understanding how the condition of the nerve affects cochlear implant function and how we might use that understanding to improve the quality of perception that patients experience using the implant. These studies also motivate efforts to improve th ...
... stimulation. One of the first challenges we face is understanding how the condition of the nerve affects cochlear implant function and how we might use that understanding to improve the quality of perception that patients experience using the implant. These studies also motivate efforts to improve th ...
Cochlear Implants and Auditory Brainstem Implants
... II. An external signal/speech processor, which selects and arranges sounds picked up by the microphone; III. An external transmitter and an internal receiver, implanted in the temporal bone, that receives signals from the speech processor and converts them into electrical impulses; and IV. An electr ...
... II. An external signal/speech processor, which selects and arranges sounds picked up by the microphone; III. An external transmitter and an internal receiver, implanted in the temporal bone, that receives signals from the speech processor and converts them into electrical impulses; and IV. An electr ...
Critical Review: Using cortical auditory evoked potentials (CAEP) as
... children and 10 adults with normal hearing, and 6 children and 6 adults with profound hearing loss that received a unilateral cochlear implant. The average age of implantation in the children was 4.5 years, ranging from 1.5 to 6 years. The subjects were tested in a comfortable reclining chair in a s ...
... children and 10 adults with normal hearing, and 6 children and 6 adults with profound hearing loss that received a unilateral cochlear implant. The average age of implantation in the children was 4.5 years, ranging from 1.5 to 6 years. The subjects were tested in a comfortable reclining chair in a s ...
Evidence-based practice for cochlear implant referrals for infants
... language gains. This is consistent with the report of Sharma and colleagues (2004) showing changes in neural response within central auditory pathways of two children shortly after cochlear implantation at ages 13 and 14 months and the changes appeared to be related to development of early communica ...
... language gains. This is consistent with the report of Sharma and colleagues (2004) showing changes in neural response within central auditory pathways of two children shortly after cochlear implantation at ages 13 and 14 months and the changes appeared to be related to development of early communica ...
Cochlear Implants - Premier Health Plan
... It is estimated that more than 25 million Americans have hearing loss, including one out of four people older than 65.1 Hearing loss primarily affecting the external and middle ear is referred to as conductive hearing loss. The type of loss which may be helped by a cochlear implant is known as senso ...
... It is estimated that more than 25 million Americans have hearing loss, including one out of four people older than 65.1 Hearing loss primarily affecting the external and middle ear is referred to as conductive hearing loss. The type of loss which may be helped by a cochlear implant is known as senso ...
Cochlear Implantation in Patient with Cochear Nerve Deficiency: A
... Cochlear implantation is an effective method for the rehabilitation of bilateral total hearing loss. House [1] first described this procedure in 1961. This device was developed during past decades and development of the devise was resulted better hearing and recognition outcomes [2]. These technolog ...
... Cochlear implantation is an effective method for the rehabilitation of bilateral total hearing loss. House [1] first described this procedure in 1961. This device was developed during past decades and development of the devise was resulted better hearing and recognition outcomes [2]. These technolog ...
Auditory Brainstem Implants in Children: Results
... process in children should follow the same steps as in adults; nevertheless, it requires different strategies, like behavioral observations to the stimulus given and responses with a pictured loudness scale. [17] Colletti et al. [1] activated all of the ABIs with the SPEAK approach in the first 6 mo ...
... process in children should follow the same steps as in adults; nevertheless, it requires different strategies, like behavioral observations to the stimulus given and responses with a pictured loudness scale. [17] Colletti et al. [1] activated all of the ABIs with the SPEAK approach in the first 6 mo ...
Auditory Brainstem Implants in Children: Results Based on a Review
... process in children should follow the same steps as in adults; nevertheless, it requires different strategies, like behavioral observations to the stimulus given and responses with a pictured loudness scale. [17] Colletti et al. [1] activated all of the ABIs with the SPEAK approach in the first 6 mo ...
... process in children should follow the same steps as in adults; nevertheless, it requires different strategies, like behavioral observations to the stimulus given and responses with a pictured loudness scale. [17] Colletti et al. [1] activated all of the ABIs with the SPEAK approach in the first 6 mo ...
Effects of Interaural Intensity Difference on the Processing of
... as frequency, ITD, and IID constitute raw data in the present study. Responses are seldom sampled for every parameter value. Therefore, the relationship between a given parameter and impulse number must be derived from samples obtained for selected parameter values. The methods of derivation must be ...
... as frequency, ITD, and IID constitute raw data in the present study. Responses are seldom sampled for every parameter value. Therefore, the relationship between a given parameter and impulse number must be derived from samples obtained for selected parameter values. The methods of derivation must be ...
Cochlear Implants
... important to remember that it can take up to one year after the implant is activated for distinct changes to show in a child's ability to communicate. ...
... important to remember that it can take up to one year after the implant is activated for distinct changes to show in a child's ability to communicate. ...
Mechanisms of Sound Localization in Mammals
... However, auditory space is not represented in any systematic manner on the basilar membrane of the cochlea, the sensory surface of the receptor organ for hearing. Understanding the means by which sensitivity to spatial cues is computed in central neurons can therefore contribute to our understanding ...
... However, auditory space is not represented in any systematic manner on the basilar membrane of the cochlea, the sensory surface of the receptor organ for hearing. Understanding the means by which sensitivity to spatial cues is computed in central neurons can therefore contribute to our understanding ...
Mechanisms of Sound Localization in Mammals
... FIG. 2. Cues for sound localization. A: spectral analysis as a monaural cue for sound localization in the vertical plane. Interaction of a broadband sound with the head and, primarily, the outer ear alters the effective spectrum of the sound impinging on the eardrum in a manner dependent on the loca ...
... FIG. 2. Cues for sound localization. A: spectral analysis as a monaural cue for sound localization in the vertical plane. Interaction of a broadband sound with the head and, primarily, the outer ear alters the effective spectrum of the sound impinging on the eardrum in a manner dependent on the loca ...
- KoreaMed Synapse
... of ingestion [3,4,7]. Like many other ototoxins, hearing loss is of the sensorineural type with no middle or external ear involvement [3,8,9]. The degree of hearing impairment is severe to profound, and is irreversible in most cases. There have been some treatment strategies to decrease other toxic ...
... of ingestion [3,4,7]. Like many other ototoxins, hearing loss is of the sensorineural type with no middle or external ear involvement [3,8,9]. The degree of hearing impairment is severe to profound, and is irreversible in most cases. There have been some treatment strategies to decrease other toxic ...
Calyx of Held

The Calyx of Held is a particularly large synapse in the mammalian auditory central nervous system, so named by Hans Held in his 1893 article Die centrale Gehörleitung because of its resemblance to the calyx of a flower. Globular bushy cells in the anteroventral cochlear nucleus (AVCN) send axons to the contralateral medial nucleus of the trapezoid body (MNTB), where they synapse via these calyces on MNTB principal cells. These principal cells then project to the ipsilateral lateral superior olive (LSO), where they inhibit postsynaptic neurons and provide a basis for interaural level detection (ILD), required for high frequency sound localization. This synapse has been described as the largest in the brain.The related endbulb of Held is also a large axon terminal smaller synapse (15-30 µm in diameter) found in other auditory brainstem structures, namely the cochlear nucleus. As with the calyces, these synapses promote fast, efficient information transfer.The calyx of Held holds vesicles containing glutamate on the presynaptic terminal, the vesicles are released upon stimulation (originating in the auditory system). The glutamate then binds to two known glutamate receptors, AMPA- and NMDA receptors.Commonly used in research due to its large size, the calyx of Held has been used to understand a variety of mechanisms related to development of, and vesicle release of the synapse.