The Mechanism of Enterohepatic Circulation in the Formation of
... body. Hence, approximately 95 % of the bile acids distributed to the duodenum are reabsorbed into venous blood within the ileum and colon, and subsequently, through mesenteric vein, they arrive at the portal vein, finally they approach the sinusoids of the liver. And hepatocytes reuptake the bile ac ...
... body. Hence, approximately 95 % of the bile acids distributed to the duodenum are reabsorbed into venous blood within the ileum and colon, and subsequently, through mesenteric vein, they arrive at the portal vein, finally they approach the sinusoids of the liver. And hepatocytes reuptake the bile ac ...
Gene Section GAST (gastrin) Atlas of Genetics and Cytogenetics
... sorting between secretory pathways. However, unlike sulfation of the related peptide, cholecystokinin (CCK), sulfation of gastrin does not significantly affect its affinity for its physiologic receptor. Phosphorylation of serine 75 of progastrin may promote proteolytic processing at the upstream arg ...
... sorting between secretory pathways. However, unlike sulfation of the related peptide, cholecystokinin (CCK), sulfation of gastrin does not significantly affect its affinity for its physiologic receptor. Phosphorylation of serine 75 of progastrin may promote proteolytic processing at the upstream arg ...
A1018 High oleic GM soybean AppR SD1 Safety Assess AMENDED
... present at junctions associated with two of the insertion sites; neither of these ORFs is likely to be expressed due to the absence of the necessary regulatory sequences. Characterisation of Novel Protein The introduced gm-fad2-1 element is a partial sequence rather than a complete gene, therefore n ...
... present at junctions associated with two of the insertion sites; neither of these ORFs is likely to be expressed due to the absence of the necessary regulatory sequences. Characterisation of Novel Protein The introduced gm-fad2-1 element is a partial sequence rather than a complete gene, therefore n ...
Vanillin formation from ferulic acid in Vanilla planifolia is catalysed
... conclude that VpVAN is catalysing vanillin and vanillin glucoside formation from ferulic acid and ferulic acid glucoside in a coupled non-oxidative hydratase/lyase reaction. A general amino-acid sequence identity search using GenBank showed that the VpVAN protein exhibits high sequence identity to c ...
... conclude that VpVAN is catalysing vanillin and vanillin glucoside formation from ferulic acid and ferulic acid glucoside in a coupled non-oxidative hydratase/lyase reaction. A general amino-acid sequence identity search using GenBank showed that the VpVAN protein exhibits high sequence identity to c ...
Aalborg Universitet metabolic engineering approach
... Impact on the environment and on human health from the use of fossil fuels and fossil fuel dependency are some of the major problems of the 21st century. Biorefineries as a concept can be seen as one part of a solution as it gives the possibility of replacing oil refinery products with sustainable b ...
... Impact on the environment and on human health from the use of fossil fuels and fossil fuel dependency are some of the major problems of the 21st century. Biorefineries as a concept can be seen as one part of a solution as it gives the possibility of replacing oil refinery products with sustainable b ...
Metabolism of bile acids
... into hepatocytes, thereby completing the enterohepatic cycle. Bile acids serve a number of functions: (i) they are the main solutes in bile and, as such, they are important for the generation of the so-called bile salt-dependent bile flow; (ii) bile salts are indispensable for the secretion of chole ...
... into hepatocytes, thereby completing the enterohepatic cycle. Bile acids serve a number of functions: (i) they are the main solutes in bile and, as such, they are important for the generation of the so-called bile salt-dependent bile flow; (ii) bile salts are indispensable for the secretion of chole ...
Distinguishing Health Benefits of Eicosapentaenoic and
... Differential associations for cell membrane EPA and DHA levels and resting state electroencephalographic (EEG) activity have been reported. DHA was associated with fast frequency EEG activity while EPA was associated with slow frequency EEG activity in 46 adolescent boys with attention deficit hyper ...
... Differential associations for cell membrane EPA and DHA levels and resting state electroencephalographic (EEG) activity have been reported. DHA was associated with fast frequency EEG activity while EPA was associated with slow frequency EEG activity in 46 adolescent boys with attention deficit hyper ...
Propionic Acid Degradation by Syntrophic Bacteria During
... to maintain continuous and efficient biogas production. The real reasons for this are not yet fully described and as cultivation of propionate degraders is difficult, the knowledge about syntrophic organisms capable of anaerobic oxidation of propionic acid is restricted. Research allowing better underst ...
... to maintain continuous and efficient biogas production. The real reasons for this are not yet fully described and as cultivation of propionate degraders is difficult, the knowledge about syntrophic organisms capable of anaerobic oxidation of propionic acid is restricted. Research allowing better underst ...
Lipids - faculty at Chemeketa
... melting point than the unsaturated fatty acids. Because linoleic has two double bonds, it would have a lower mp than oleic acid, which has one double bond. stearic acid mp 69°C saturated oleic acid mp 13°C linoleic acid mp -17°C most unsaturated ...
... melting point than the unsaturated fatty acids. Because linoleic has two double bonds, it would have a lower mp than oleic acid, which has one double bond. stearic acid mp 69°C saturated oleic acid mp 13°C linoleic acid mp -17°C most unsaturated ...
Untitled - Shodhganga
... the precursor for all other animal steroids. The numbering system for cholesterol applies to all such molecules. Many steroids contain methyl groups at positions 10 and 13 and an 8- to 10- carbon alkyl side chain at position 17. The polyprenyl nature of this compound is particularly evident in the s ...
... the precursor for all other animal steroids. The numbering system for cholesterol applies to all such molecules. Many steroids contain methyl groups at positions 10 and 13 and an 8- to 10- carbon alkyl side chain at position 17. The polyprenyl nature of this compound is particularly evident in the s ...
Molecular Plant-Microbio Interactions
... production by environmental factors takes place at or before autoinducer production. Moreover, the results show that autoinducer production not only is induced by a high optical density but also can be induced by certain environmental conditions. We discuss our findings in relation to the success of ...
... production by environmental factors takes place at or before autoinducer production. Moreover, the results show that autoinducer production not only is induced by a high optical density but also can be induced by certain environmental conditions. We discuss our findings in relation to the success of ...
Molecular basis of hepatic carnitine palmitoyltransferase I deficiency
... zyme (CPT I) is localized in the outer-mitochondrial membrane and converts the fatty acyl-CoA ester to its carnitine ester. This carnitine ester is subsequently transported across the mitochondrial inner membrane by CAC which belongs to the mitochondrial carrier family. Once inside the mitochondrial ...
... zyme (CPT I) is localized in the outer-mitochondrial membrane and converts the fatty acyl-CoA ester to its carnitine ester. This carnitine ester is subsequently transported across the mitochondrial inner membrane by CAC which belongs to the mitochondrial carrier family. Once inside the mitochondrial ...
C 2 R
... of BM3 Cys400) to the heme-iron, instead of a thiolate which is required to produce the active P450 (33). Mutation F87S, when applied to wild-type BM3 was previously shown to be an active enzyme with changed regioselectivity in lauric acid hydroxylation (19). However, carbonmonoxide difference spect ...
... of BM3 Cys400) to the heme-iron, instead of a thiolate which is required to produce the active P450 (33). Mutation F87S, when applied to wild-type BM3 was previously shown to be an active enzyme with changed regioselectivity in lauric acid hydroxylation (19). However, carbonmonoxide difference spect ...
Structural and Functional Basis of
... acid to prostaglandin G2 (PGG2) and the reduction of PGG2 to PGH2. Arachidonic acid oxygenation occurs in the cyclooxygenase active site, and PGG2 reduction occurs in the peroxidase active site. PGH2 diffuses from the COX proteins and is transformed by different tissue-specific isomerases to prostag ...
... acid to prostaglandin G2 (PGG2) and the reduction of PGG2 to PGH2. Arachidonic acid oxygenation occurs in the cyclooxygenase active site, and PGG2 reduction occurs in the peroxidase active site. PGH2 diffuses from the COX proteins and is transformed by different tissue-specific isomerases to prostag ...
Chapter 17 Lipids
... melting point than the unsaturated fatty acids. Because linoleic has two double bonds, it would have a lower mp than oleic acid, which has one double bond. stearic acid mp 69°C saturated oleic acid mp 13°C linoleic acid mp -17°C most unsaturated ...
... melting point than the unsaturated fatty acids. Because linoleic has two double bonds, it would have a lower mp than oleic acid, which has one double bond. stearic acid mp 69°C saturated oleic acid mp 13°C linoleic acid mp -17°C most unsaturated ...
9. Wakil, S. J., Green, DE, Mii, S., and Mahler, HR (1954) Studies on
... 6. Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high carbohydrate diets. Fatty acid oxidation rates in the soleus muscle and in hepatocytes of Acc2-/- mice were significantly higher than those of WT cohorts and were not affected by the addition ...
... 6. Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high carbohydrate diets. Fatty acid oxidation rates in the soleus muscle and in hepatocytes of Acc2-/- mice were significantly higher than those of WT cohorts and were not affected by the addition ...
MCPBA (m-Chloroperoxybenzoic Acid) - Sigma
... I.R. Subbaraman and co-workers21 reported that cytosine, adenine and their derivatives are oxidized to N-oxides while uracil, thymine, guanosine and their derivatives give ring-cleavage products. However, M.R. Harden et al.22 indicated that N(1)-oxides were obtained from adenine, cytosine and uracil ...
... I.R. Subbaraman and co-workers21 reported that cytosine, adenine and their derivatives are oxidized to N-oxides while uracil, thymine, guanosine and their derivatives give ring-cleavage products. However, M.R. Harden et al.22 indicated that N(1)-oxides were obtained from adenine, cytosine and uracil ...
Effects of Xylitol on S. mutans
... Inhibition of acid production by MS from dietary sugars Inhibition of MS growth Selection of a new less virulent MS population Reduction of the transmission / implantation of Ms ...
... Inhibition of acid production by MS from dietary sugars Inhibition of MS growth Selection of a new less virulent MS population Reduction of the transmission / implantation of Ms ...
NON-RADIOACTIVE ASSAY FOR ACETYL-CoA
... But whereas the citrate synthase reaction in the pyruvate carboxylase assay contains excess acetylCoA and measures how much oxaloacetate was produced in the first reaction, the citrate synthase reaction for this assay contains excess oxaloacetate and measures how much acetyl-CoA was consumed in the ...
... But whereas the citrate synthase reaction in the pyruvate carboxylase assay contains excess acetylCoA and measures how much oxaloacetate was produced in the first reaction, the citrate synthase reaction for this assay contains excess oxaloacetate and measures how much acetyl-CoA was consumed in the ...
BIOTRANSFORMATION OF DRUGS
... Oxygenation involves insertion of an O atom (from O2) into a C-H bond, forming a hydroxylated metabolite, or into a C=C double bond, forming an epoxide. A hydroxylated metabolite may be stable, or unstable. From an unstable hydroxylated metabolite a group may break off spontaneously: an alkyl group, ...
... Oxygenation involves insertion of an O atom (from O2) into a C-H bond, forming a hydroxylated metabolite, or into a C=C double bond, forming an epoxide. A hydroxylated metabolite may be stable, or unstable. From an unstable hydroxylated metabolite a group may break off spontaneously: an alkyl group, ...
Lipids - csfcbiology
... Lipids are often stored in special adipose tissue, within large fat cells (above). ...
... Lipids are often stored in special adipose tissue, within large fat cells (above). ...
Title Biotin Biosynthesis in Microorganisms (Commemoration Issue
... detected the reaction products by radioautography. Radioactive biotin, biocytin and biocytin sulfoxide were formed. The authors74>also tested the effect of various sulfur compounds using resting cells of Rhodotorulaglutinis which forms appreciable amounts of biotin from DTB. In the presence of DTB, ...
... detected the reaction products by radioautography. Radioactive biotin, biocytin and biocytin sulfoxide were formed. The authors74>also tested the effect of various sulfur compounds using resting cells of Rhodotorulaglutinis which forms appreciable amounts of biotin from DTB. In the presence of DTB, ...
Cholesterol Homeostasis - Sigma
... cholesterol levels are tightly controlled by complex mechanisms. When dietary intake of cholesterol is high, biosynthesis is reduced. However, the body’s homeostatic mechanisms can be inadequate when baseline endogenous cholesterol biosynthesis becomes excessive or when dietary cholesterol intake is ...
... cholesterol levels are tightly controlled by complex mechanisms. When dietary intake of cholesterol is high, biosynthesis is reduced. However, the body’s homeostatic mechanisms can be inadequate when baseline endogenous cholesterol biosynthesis becomes excessive or when dietary cholesterol intake is ...