LIPIDS CHEMISTRY
... occurring steroids: A typical member of this group is cholesterol. Certain facts have to be considered when drawing steroid formula: 1) There is always oxygen in the form of hydroxyl or ketone on C3. ...
... occurring steroids: A typical member of this group is cholesterol. Certain facts have to be considered when drawing steroid formula: 1) There is always oxygen in the form of hydroxyl or ketone on C3. ...
Homeostasis pH
... acid–bicarbonate buffer system is to protect against the effects of the organic and fixed acids generated through metabolic activity. In effect, it takes the H released by these acids and generates carbonic acid that dissociates into water and carbon dioxide, which can easily be eliminated at the l ...
... acid–bicarbonate buffer system is to protect against the effects of the organic and fixed acids generated through metabolic activity. In effect, it takes the H released by these acids and generates carbonic acid that dissociates into water and carbon dioxide, which can easily be eliminated at the l ...
fulltext
... The activation of D-Glc via UDP-D-Glc pyrophosphorylase (EC 2.7.7.9) or sucrose synthase (EC 2.4.1.13) yields a cytoplasmatic pool of UDPD-Glc which functions, e.g., as a donor of glucose for the synthesis of cellulose and glycogen. UDPD-Glc also serves as a substrate for the synthesis of other nucl ...
... The activation of D-Glc via UDP-D-Glc pyrophosphorylase (EC 2.7.7.9) or sucrose synthase (EC 2.4.1.13) yields a cytoplasmatic pool of UDPD-Glc which functions, e.g., as a donor of glucose for the synthesis of cellulose and glycogen. UDPD-Glc also serves as a substrate for the synthesis of other nucl ...
Preparation of Human Metabolites of Propranolol Using Laboratory-Evolved Bacterial Cytochromes P450
... (Markham and Wagstaff, 1998), early on in the drug development process could result in the early identification of safer, more well tolerated therapies. Such studies, however, can require large quantities of the pure metabolites, and these may be difficult to synthesize. An alternative to chemical s ...
... (Markham and Wagstaff, 1998), early on in the drug development process could result in the early identification of safer, more well tolerated therapies. Such studies, however, can require large quantities of the pure metabolites, and these may be difficult to synthesize. An alternative to chemical s ...
Lipids as Tumoricidal Components of Human
... MAPK signaling, and especially Na⫹ or K⫹ fluxes were essential for these responses to occur. In a screen for suitable fatty acids cofactors, C18:1, cis-monounsaturated fatty acids were identified as optimal for HAMLET formation (26), suggesting that these fatty acids may share specific structural fe ...
... MAPK signaling, and especially Na⫹ or K⫹ fluxes were essential for these responses to occur. In a screen for suitable fatty acids cofactors, C18:1, cis-monounsaturated fatty acids were identified as optimal for HAMLET formation (26), suggesting that these fatty acids may share specific structural fe ...
Targeting Acetyl-CoA Carboxylases: Small
... Recent studies from our laboratory have revealed a novel regulatory mechanism on ACC activity. Aldo-keto reductase family 1 member B10 (AKR1B10), a NADPH-dependent xenobiotic reductase primarily expressed in the colon and small intestine [61-63], upregulated simultaneously with ACC1 in tumorigenic t ...
... Recent studies from our laboratory have revealed a novel regulatory mechanism on ACC activity. Aldo-keto reductase family 1 member B10 (AKR1B10), a NADPH-dependent xenobiotic reductase primarily expressed in the colon and small intestine [61-63], upregulated simultaneously with ACC1 in tumorigenic t ...
Chemical Inactivation of the Cinnamate 4
... fairly stable, but the carbene can be displaced at high-substrate concentration. In elicitor-treated BY2 cells, PIP also behaves as an effective C4H inactivator and inhibits the formation of p-coumarate and accumulation of the downstream metabolite scopoletin (Schalk et al., 1998). A single branch p ...
... fairly stable, but the carbene can be displaced at high-substrate concentration. In elicitor-treated BY2 cells, PIP also behaves as an effective C4H inactivator and inhibits the formation of p-coumarate and accumulation of the downstream metabolite scopoletin (Schalk et al., 1998). A single branch p ...
a review on biochemical mechanism of fatty acids synthesis and oil
... In plants, fatty acid biosynthesis process initiated in plastid and ended in the endoplasmic reticulum. A series of biochemical steps are involved in TAG formation and many of the genes involved in this process have been identified. The quality of seed oil depends on the type of fatty acids esterifi ...
... In plants, fatty acid biosynthesis process initiated in plastid and ended in the endoplasmic reticulum. A series of biochemical steps are involved in TAG formation and many of the genes involved in this process have been identified. The quality of seed oil depends on the type of fatty acids esterifi ...
Full-Text PDF
... across biological membranes [1]. SLC transporters are located in various membranes, such as plasma-, lysosomal-, inner mitochondrial-, peroxisomal membrane, and endoplasmic reticulum in an organ or cell type specific manner. Several SLC transporters have been identified as tumor suppressors [2–5] an ...
... across biological membranes [1]. SLC transporters are located in various membranes, such as plasma-, lysosomal-, inner mitochondrial-, peroxisomal membrane, and endoplasmic reticulum in an organ or cell type specific manner. Several SLC transporters have been identified as tumor suppressors [2–5] an ...
ALT
... the liver. In addition, it is also active in the heart, skeletal muscle, pancreas, and the kidney. GPT (ALT) activity in the liver is about 3,000 times higher than its activity in the serum. Only if cells are damaged GPT (ALT) will be excreted into the blood. In the plasma, GPT (ALT) has no biologic ...
... the liver. In addition, it is also active in the heart, skeletal muscle, pancreas, and the kidney. GPT (ALT) activity in the liver is about 3,000 times higher than its activity in the serum. Only if cells are damaged GPT (ALT) will be excreted into the blood. In the plasma, GPT (ALT) has no biologic ...
APPLICATION OF LACTIC ACID BACTERIA TO CONTROL
... (Lie, 1995). As well as with strain of L. Plantarum isolated from fish sauce which produced lactic acid at 0.961% on day-3 of incubation was also able to inhibit S. Typhimurium effectively. It seemed that the inhibitory activity of LAB against S. Typhimurium was not only due to the organic acids pro ...
... (Lie, 1995). As well as with strain of L. Plantarum isolated from fish sauce which produced lactic acid at 0.961% on day-3 of incubation was also able to inhibit S. Typhimurium effectively. It seemed that the inhibitory activity of LAB against S. Typhimurium was not only due to the organic acids pro ...
Microbial production of hyaluronic acid: current state, challenges
... production. The pH and temperature for HA production by S. zooepidemicus were usually at 7.0 and 37°C, respectively [26,27]. The microbial HA production by S. zooepidemicus is a typically viscous process, and thus mixing performance and oxygen mass transfer rate significantly influence HA production ...
... production. The pH and temperature for HA production by S. zooepidemicus were usually at 7.0 and 37°C, respectively [26,27]. The microbial HA production by S. zooepidemicus is a typically viscous process, and thus mixing performance and oxygen mass transfer rate significantly influence HA production ...
Lactic Acid : Brief History
... cycle (TCA cycle), or the Krebs cycle, is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation ...
... cycle (TCA cycle), or the Krebs cycle, is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation ...
proper omega-3 Olive oil Canola oil Coconut oil Palm oil
... dietary fats this strengthens a shift of focus from less fat in general to more of healthier fats. Change depends on informed opinion leaders and consumers, but scientific independent support is needed. Disappearing myths: Low-Carb diets typically include eggs rich in cholesterol and butter rich in ...
... dietary fats this strengthens a shift of focus from less fat in general to more of healthier fats. Change depends on informed opinion leaders and consumers, but scientific independent support is needed. Disappearing myths: Low-Carb diets typically include eggs rich in cholesterol and butter rich in ...
Studies on a Mutant Strain of Escherichia coli which
... requirement for lysine+methionine and was used for all growth tests in solid medium. A typical response after using this inocdum and incubating for 24 hr. at 87" is shown in PI. 1, fig. 1. A smaller inoculum required prolonged incubation to demonstrate the response, whilst a larger inoculum produced ...
... requirement for lysine+methionine and was used for all growth tests in solid medium. A typical response after using this inocdum and incubating for 24 hr. at 87" is shown in PI. 1, fig. 1. A smaller inoculum required prolonged incubation to demonstrate the response, whilst a larger inoculum produced ...
Received June 19, 1964.
... sequence, although comparisons are somewhat difficult because only the DL-forms of the latter 2 were available for studies. The reactions discussed also indicate that uridylic acid should be labelled prior to cytidylic acid upon addition of any previous precursor. Table I shows that in all cases whe ...
... sequence, although comparisons are somewhat difficult because only the DL-forms of the latter 2 were available for studies. The reactions discussed also indicate that uridylic acid should be labelled prior to cytidylic acid upon addition of any previous precursor. Table I shows that in all cases whe ...
Review Prostaglandins in non-insectan invertebrates: recent
... contraction and cervical ripening (Johnson and Everitt, 2000). In the kidney PGs, including PGE2 and PGI2, modulate haemodynamics as a result of their vasodilatory activity and also have an effect on both salt and water balance (DuBois et al., 1998; Frolich and Stichtenoth, 1998). Finally, PGs play ...
... contraction and cervical ripening (Johnson and Everitt, 2000). In the kidney PGs, including PGE2 and PGI2, modulate haemodynamics as a result of their vasodilatory activity and also have an effect on both salt and water balance (DuBois et al., 1998; Frolich and Stichtenoth, 1998). Finally, PGs play ...
Identification of Two Mammalian Reductases
... ¶ Pew Scholar in the Biomedical Sciences. Recipient of the Established Investigator Grant from the American Heart Association. To whom correspondence should be addressed: Depts. of Internal Medicine and Molecular Genetics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Rm. ...
... ¶ Pew Scholar in the Biomedical Sciences. Recipient of the Established Investigator Grant from the American Heart Association. To whom correspondence should be addressed: Depts. of Internal Medicine and Molecular Genetics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Rm. ...
The Chemical Composition of the Cell Wall in some Gram
... London Hospital, from a throat swab. Streptococci of other Lancefield’s groups were obtained from the National Collection of Type Cultures. Staphylococcus aureus, strains 1, 2 and 3, isolated from nasal swabs, all coagulase-positive; S. albus strains 1, 2 and 3, isolated from nasal swabs, all coagul ...
... London Hospital, from a throat swab. Streptococci of other Lancefield’s groups were obtained from the National Collection of Type Cultures. Staphylococcus aureus, strains 1, 2 and 3, isolated from nasal swabs, all coagulase-positive; S. albus strains 1, 2 and 3, isolated from nasal swabs, all coagul ...
The Future of Butyric Acid in Industry (PDF Available)
... Butyric acid has many uses in different industries, and currently there is a great interest in using it as a precursor to biofuels. Due to increases in petroleum prices as well as a continuous reduction in petroleum availability and a growing need for clean energy sources, research has recently been ...
... Butyric acid has many uses in different industries, and currently there is a great interest in using it as a precursor to biofuels. Due to increases in petroleum prices as well as a continuous reduction in petroleum availability and a growing need for clean energy sources, research has recently been ...
The Chemical Composition of the Cell Wall in some
... London Hospital, from a throat swab. Streptococci of other Lancefield’s groups were obtained from the National Collection of Type Cultures. Staphylococcus aureus, strains 1, 2 and 3, isolated from nasal swabs, all coagulase-positive; S. albus strains 1, 2 and 3, isolated from nasal swabs, all coagul ...
... London Hospital, from a throat swab. Streptococci of other Lancefield’s groups were obtained from the National Collection of Type Cultures. Staphylococcus aureus, strains 1, 2 and 3, isolated from nasal swabs, all coagulase-positive; S. albus strains 1, 2 and 3, isolated from nasal swabs, all coagul ...
the relationship between calcium
... output of 17-ketosteroids, the Thorn test (with adrenaline) and the blood sugar levels after insulin administration. In three cases the 17-ketosteroid output in the urine showed a rise before onset of treatmrent (average for that age not higher than I mg. per day). The drop in eosinophils following ...
... output of 17-ketosteroids, the Thorn test (with adrenaline) and the blood sugar levels after insulin administration. In three cases the 17-ketosteroid output in the urine showed a rise before onset of treatmrent (average for that age not higher than I mg. per day). The drop in eosinophils following ...
PPT File
... clotting, regulation of blood pressure, gastric acid secretion, and in a variety of other processes important to human health. All eicosanoids are derived from arachidonic acid, the 20-C PUFA. Three classes of eicosanoids: - Prostaglandins (PG) - Thromboxanes (Tx) - Leukotrienes (LT) ...
... clotting, regulation of blood pressure, gastric acid secretion, and in a variety of other processes important to human health. All eicosanoids are derived from arachidonic acid, the 20-C PUFA. Three classes of eicosanoids: - Prostaglandins (PG) - Thromboxanes (Tx) - Leukotrienes (LT) ...
Full Text PDF
... DCA, and UDCA were moderately metabolized into their corresponding 24-GlcUs. In contrast to these bile acids, the formation of the 24-GlcU of trihydroxylated CA, which is more water soluble than the other common bile acids, was barely detected. No substrate-saturation curve was obtained for LCA, and ...
... DCA, and UDCA were moderately metabolized into their corresponding 24-GlcUs. In contrast to these bile acids, the formation of the 24-GlcU of trihydroxylated CA, which is more water soluble than the other common bile acids, was barely detected. No substrate-saturation curve was obtained for LCA, and ...
A novel multifunctional O-methyltransferase implicated in a dual
... For this reason, methylating enzymes, O-methyltransferases (OMTs), involved in the lignin biosynthetic pathway, particularly those in angiosperms, have been extensively studied (for reviews, see refs. 5–7) and, recently, have been regarded with considerable interest as targets for biotechnological m ...
... For this reason, methylating enzymes, O-methyltransferases (OMTs), involved in the lignin biosynthetic pathway, particularly those in angiosperms, have been extensively studied (for reviews, see refs. 5–7) and, recently, have been regarded with considerable interest as targets for biotechnological m ...