Planta
... into isocitrate, the latter is converted to 2OG by NADPICDH in the cytosol (Sadka et al. 2000b). It is assumed that the catabolized citrate is converted into amino acids (Sadka et al. 2000c; Cercos et al. 2006), although other metabolic pathways, such as gluconeogenesis or acetyl-CoA metabolism, may ...
... into isocitrate, the latter is converted to 2OG by NADPICDH in the cytosol (Sadka et al. 2000b). It is assumed that the catabolized citrate is converted into amino acids (Sadka et al. 2000c; Cercos et al. 2006), although other metabolic pathways, such as gluconeogenesis or acetyl-CoA metabolism, may ...
Increasing the thermostability of sucrose
... desired improvement is achieved. In this way, the T50 of the lipase from Bacillus subtilis could be increased from 48 to 938C by the substitution of only seven amino acid residues (Reetz et al., 2006). To reduce the size of the libraries and thus the screening effort, an extension of the B-FIT proce ...
... desired improvement is achieved. In this way, the T50 of the lipase from Bacillus subtilis could be increased from 48 to 938C by the substitution of only seven amino acid residues (Reetz et al., 2006). To reduce the size of the libraries and thus the screening effort, an extension of the B-FIT proce ...
Synthesis, Molecular Docking, and Biological Evaluation of Some
... synthesized and evaluated for their anti-inflammatory activity as well as COX-2 selectivity (17–19). It was interesting also to synthesize a series of pyrazole derivatives as pyrazole moiety is still a target for many researchers in their seek for new and selective anti-inflammatory agents (20–23). ...
... synthesized and evaluated for their anti-inflammatory activity as well as COX-2 selectivity (17–19). It was interesting also to synthesize a series of pyrazole derivatives as pyrazole moiety is still a target for many researchers in their seek for new and selective anti-inflammatory agents (20–23). ...
FEBS Letters
... glutamate were said to be transported from vegetative cells to heterocysts [l-3]. The latter statement is not so well substantiated by experimental findings as the former. The disaccharide has not yet been identified. The evidence for the transport of glutamate mainly stems from [4-61 that carbon ca ...
... glutamate were said to be transported from vegetative cells to heterocysts [l-3]. The latter statement is not so well substantiated by experimental findings as the former. The disaccharide has not yet been identified. The evidence for the transport of glutamate mainly stems from [4-61 that carbon ca ...
acetyl CoA - LSU School of Medicine
... ketone bodies (acetoacetate, b- (or 3-) hydroxybutyrate, acetone). B) Transported to other tissues, converted to acetyl CoA and metabolized by the citric acid cycle. C) Importance - water-soluble; produced in liver when excess acetyl CoA exceeds the oxidative capacity; can be used by skeletal and ca ...
... ketone bodies (acetoacetate, b- (or 3-) hydroxybutyrate, acetone). B) Transported to other tissues, converted to acetyl CoA and metabolized by the citric acid cycle. C) Importance - water-soluble; produced in liver when excess acetyl CoA exceeds the oxidative capacity; can be used by skeletal and ca ...
Paracetamol (Acetaminophen): mechanisms of action
... PGHS enzyme when combined with the ‘peroxide tone’ of different cells, explains paracetamol’s lack of platelet and anti-inflammatory effects. An active metabolite has been identified in mice. This metabolite (p-aminophenol) is then conjugated with arachidonic acid by fatty acid amide hydrolase to fo ...
... PGHS enzyme when combined with the ‘peroxide tone’ of different cells, explains paracetamol’s lack of platelet and anti-inflammatory effects. An active metabolite has been identified in mice. This metabolite (p-aminophenol) is then conjugated with arachidonic acid by fatty acid amide hydrolase to fo ...
Nonenzymatic, Self-Elimination Degradation
... release of glutamate accompanied by the release of cysteinyl-glycine. The resulting gglutamyl amino acids formed by g-glutamyl transpeptidase are transported into cells where g-glutamyl cyclotransferase converts these compounds into the corresponding amino acid and 5-oxo-l-proline. The intracellular ...
... release of glutamate accompanied by the release of cysteinyl-glycine. The resulting gglutamyl amino acids formed by g-glutamyl transpeptidase are transported into cells where g-glutamyl cyclotransferase converts these compounds into the corresponding amino acid and 5-oxo-l-proline. The intracellular ...
Regulation of Elovl and fatty acid metabolism
... indisputable for life. These compounds include different fats such as oils, waxes, sterols, fatsoluble vitamins, glycerophospholipids, sphingolipids, mono-, di- and triglycerides. Fatty acids (FA) do not only serve as a major source of energy, but are also crucial structural components of membranes. ...
... indisputable for life. These compounds include different fats such as oils, waxes, sterols, fatsoluble vitamins, glycerophospholipids, sphingolipids, mono-, di- and triglycerides. Fatty acids (FA) do not only serve as a major source of energy, but are also crucial structural components of membranes. ...
FAT SYNTHESIS AND DEGRADATION
... Once fatty acids have been made 16 carbons long, they can be lengthened by adding 2 carbon atoms at a time with malonyl-CoA in a reaction that looks a lot like the first step of fatty acid synthesis. However, the elongation reaction is carried out on the fatty acyl-CoA and by an enzyme that is diffe ...
... Once fatty acids have been made 16 carbons long, they can be lengthened by adding 2 carbon atoms at a time with malonyl-CoA in a reaction that looks a lot like the first step of fatty acid synthesis. However, the elongation reaction is carried out on the fatty acyl-CoA and by an enzyme that is diffe ...
Topic: Exchange and functions of carbohydrates
... Mucous substances. The basis of mucous substances are glycoproteins (mucoproteins, mucopolysaccharides). They prevent the walls of the stomach from denaturated effect of HCl and from digestive effect of pepsin; also they have antiseptic action. Inner factor of Kastle. Glycoprotein, formed in the muc ...
... Mucous substances. The basis of mucous substances are glycoproteins (mucoproteins, mucopolysaccharides). They prevent the walls of the stomach from denaturated effect of HCl and from digestive effect of pepsin; also they have antiseptic action. Inner factor of Kastle. Glycoprotein, formed in the muc ...
Alkaline Defence Program
... points out in another paper that the average diet today is high in sodium and low in potassium, contrary to the original genetic makeup of the human body. It is this reduction of bicarbonates in the blood that affects blood flow and makes it difficult to manage the continuous outpour of acid, making ...
... points out in another paper that the average diet today is high in sodium and low in potassium, contrary to the original genetic makeup of the human body. It is this reduction of bicarbonates in the blood that affects blood flow and makes it difficult to manage the continuous outpour of acid, making ...
Disposition of Glutathione Conjugates in Rats by a Novel Glutamic
... For analyses of the acetaminophen metabolites, HPLC was carried out using a Hewlett-Packard HPLC system (HP 1100) coupled in sequence to a Waters symmetry C18 column (150 ⫻ 3.9 mm, 5 m). The metabolites were separated by a gradient solvent system consisting of a mixture of acetonitrile and 0.05% TF ...
... For analyses of the acetaminophen metabolites, HPLC was carried out using a Hewlett-Packard HPLC system (HP 1100) coupled in sequence to a Waters symmetry C18 column (150 ⫻ 3.9 mm, 5 m). The metabolites were separated by a gradient solvent system consisting of a mixture of acetonitrile and 0.05% TF ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
... systems. An important requirement for the improvement of secondary metabolite synthesis in plants is the understanding of the metabolic pathways and the enzymology of the biosynthesis of particular products. The 8000 or so phenolic compounds are formed by way of either the Shikimic acid pathway or t ...
... systems. An important requirement for the improvement of secondary metabolite synthesis in plants is the understanding of the metabolic pathways and the enzymology of the biosynthesis of particular products. The 8000 or so phenolic compounds are formed by way of either the Shikimic acid pathway or t ...
Garcia and Oh2 - Saddleback College
... activity time of the 10 subjects when taking no supplement, Tums® and Cytomax®. Although the results. Although when taking the Tums® we did see an increase in the subject’s performance, the results were not significantly different to those without supplements. This demonstrates that there is no adva ...
... activity time of the 10 subjects when taking no supplement, Tums® and Cytomax®. Although the results. Although when taking the Tums® we did see an increase in the subject’s performance, the results were not significantly different to those without supplements. This demonstrates that there is no adva ...
Uric acid
... binding to them. b. Allopurinol increases excretion of uric acid by the kidneys. c. Allopurinol inhibits the enzyme that makes uric ...
... binding to them. b. Allopurinol increases excretion of uric acid by the kidneys. c. Allopurinol inhibits the enzyme that makes uric ...
Metabolism of Lipids
... Include prostaglandins, prostacyclins, thromboxanes, leukotrienes Physiological effects at very low concentrations Many of their effects mediated by cyclic AMP or calcium second messengers Unlike hormones, not transported in the blood Local mediators that act where synthesized or in adjacent ce ...
... Include prostaglandins, prostacyclins, thromboxanes, leukotrienes Physiological effects at very low concentrations Many of their effects mediated by cyclic AMP or calcium second messengers Unlike hormones, not transported in the blood Local mediators that act where synthesized or in adjacent ce ...
adaptations to a terrestrial existence by the robber crab, birgus latro l.
... reported to lack these enzymes and urea cannot be a major excretory product in the group (Claybrook, 1983). Some urea may be formed from dietary arginine but arginine is an essential amino acid in crustaceans (Claybrook, 1983) and is unlikely to contribute more than a small fraction of total excrete ...
... reported to lack these enzymes and urea cannot be a major excretory product in the group (Claybrook, 1983). Some urea may be formed from dietary arginine but arginine is an essential amino acid in crustaceans (Claybrook, 1983) and is unlikely to contribute more than a small fraction of total excrete ...
The main theoretical questions
... not incorporated into tissue nucleic acids. Humans biosynthesize the purines and pyrimidines of tissue nucleic acids, ATP, NAD+, coenzyme A, etc, from amphibolic intermediates. However, injected purine or pyrimidine analogs, including potential anticancer drugs, may be incorporated into DNA. The bio ...
... not incorporated into tissue nucleic acids. Humans biosynthesize the purines and pyrimidines of tissue nucleic acids, ATP, NAD+, coenzyme A, etc, from amphibolic intermediates. However, injected purine or pyrimidine analogs, including potential anticancer drugs, may be incorporated into DNA. The bio ...
Characterization of the novel antibacterial peptide Leucrocin from
... In addition to their action towards microbes, some antimicrobial peptides can function as regulatory molecules in the host. For example, in vitro studies suggest that defensins attract phagocytes and lymphocytes to sites of infection, inhibit the release of cortisol from adrenal cells, induce the pr ...
... In addition to their action towards microbes, some antimicrobial peptides can function as regulatory molecules in the host. For example, in vitro studies suggest that defensins attract phagocytes and lymphocytes to sites of infection, inhibit the release of cortisol from adrenal cells, induce the pr ...
BMC Struct Biol. BMC Struct Biol. 2003
... Tsuchida: eishun/at/mn.waseda.ac.jp; Stephen Curry:s.curry/at/imperial.ac.uk Abstract Abstract Background Human serum albumin (HSA) is an abundant plasma protein that binds a wide variety of hydrophobic ligands including fatty acids, bilirubin, thyroxine and hemin. Although HSA-heme complexes do not ...
... Tsuchida: eishun/at/mn.waseda.ac.jp; Stephen Curry:s.curry/at/imperial.ac.uk Abstract Abstract Background Human serum albumin (HSA) is an abundant plasma protein that binds a wide variety of hydrophobic ligands including fatty acids, bilirubin, thyroxine and hemin. Although HSA-heme complexes do not ...
regulation of fatty acid synthesis
... synthesis must also consider those reactions that precede and follow these two enzyme systems. It is not fully understood which reactions are responsible for providing acetyl-CoA to ACCase, but extensive experiments with leaf tissue indicate that acetyl-CoA synthetase can rapidly convert acetate to ...
... synthesis must also consider those reactions that precede and follow these two enzyme systems. It is not fully understood which reactions are responsible for providing acetyl-CoA to ACCase, but extensive experiments with leaf tissue indicate that acetyl-CoA synthetase can rapidly convert acetate to ...
Modifying the chain-length selectivity of the
... acyl chain-length selectivity of the in vitro expressed lipases against p-nitrophenyl butyrate, p-nitrophenyl caprylate and p-nitrophenyl palmitate, was compared by their relative hydrolysis rates. Two mutant lipases, L167V and F119A/ L167M, which showed a significant shift in substrate selectivity ...
... acyl chain-length selectivity of the in vitro expressed lipases against p-nitrophenyl butyrate, p-nitrophenyl caprylate and p-nitrophenyl palmitate, was compared by their relative hydrolysis rates. Two mutant lipases, L167V and F119A/ L167M, which showed a significant shift in substrate selectivity ...
here - Solve ME/CFS Initiative
... Studies show that SCFA have this effect by triggering AMPK. AMPK is the master switch that increases lipid and amino acid production of ATP. Expected the increase in SCFA to also indicate an effect on hypometabolism in ME/CFS. Maybe something more at work. Reduced amino acids in feces appears linked ...
... Studies show that SCFA have this effect by triggering AMPK. AMPK is the master switch that increases lipid and amino acid production of ATP. Expected the increase in SCFA to also indicate an effect on hypometabolism in ME/CFS. Maybe something more at work. Reduced amino acids in feces appears linked ...
25 WORDS: ALANINE Alanine, C3H7NO2, is one of the 20 amino
... acids such as valine, leucine, and isoleucine. Alanine is a non-essential amino acid and is used by the body to build protein and was first isolated in 1879. It has also demonstrated a cholesterol-reducing effect in rats. Cindy Alanine is an amino acid that is prominent in many proteins. Sources of ...
... acids such as valine, leucine, and isoleucine. Alanine is a non-essential amino acid and is used by the body to build protein and was first isolated in 1879. It has also demonstrated a cholesterol-reducing effect in rats. Cindy Alanine is an amino acid that is prominent in many proteins. Sources of ...
Thermodynamic and Biophysical Characterization of Cytochrome P450
... polycyclic azole drugs with similar affinity to that for fatty acids (Kd values in the range 0.1-160 µM). Sigmoidal binding curves for titration of BioI with azole drugs suggests a cooperative process in this case. BioI as isolated from Escherichia coli is in a mixed heme iron spin state. Alteration ...
... polycyclic azole drugs with similar affinity to that for fatty acids (Kd values in the range 0.1-160 µM). Sigmoidal binding curves for titration of BioI with azole drugs suggests a cooperative process in this case. BioI as isolated from Escherichia coli is in a mixed heme iron spin state. Alteration ...