Viva Voce : Orals in Biochemistry
... The idea of writing this book of VIVA VOCE/ORALS IN BIOCHEMISTRY is that it should be much helpful to the MBBS and M.Sc. (Medical Science) students and post-graduate students for the preparation of examination. Though it is not a textbook of medical Biochemistry, it is framed in the form of question ...
... The idea of writing this book of VIVA VOCE/ORALS IN BIOCHEMISTRY is that it should be much helpful to the MBBS and M.Sc. (Medical Science) students and post-graduate students for the preparation of examination. Though it is not a textbook of medical Biochemistry, it is framed in the form of question ...
Bile acids activate ryanodine receptors in pancreatic acinar cells via
... IP3 R or RyR were blocked, but failed when both IP3 R and RyRs were inhibited [12]. Moreover, both dantrolene and ryanodine converted bile acid-induced sustained intracellular [Ca2+ ] elevations to physiological Ca2+ oscillations in intact cells [4]. Although, these data suggest that bile acids trig ...
... IP3 R or RyR were blocked, but failed when both IP3 R and RyRs were inhibited [12]. Moreover, both dantrolene and ryanodine converted bile acid-induced sustained intracellular [Ca2+ ] elevations to physiological Ca2+ oscillations in intact cells [4]. Although, these data suggest that bile acids trig ...
Peer-reviewed Article PDF
... the Citric Acid Cycle [1]. Citrate synthase is localized within eukaryotic cells in the mitochondrial matrix, and it is commonly used as a quantitative enzyme marker for the presence of intact mitochondria. Oxaloacetate - the first substrate which binds to the citrate synthase induces the enzyme to ...
... the Citric Acid Cycle [1]. Citrate synthase is localized within eukaryotic cells in the mitochondrial matrix, and it is commonly used as a quantitative enzyme marker for the presence of intact mitochondria. Oxaloacetate - the first substrate which binds to the citrate synthase induces the enzyme to ...
Phospholipids of some marine microalgae: Identification, antivirus
... Total Phosphorus content of marine algal phospholipids fraction was presented in Table (1). The results showed that the maximum content was observed in D. fasciola (0.86 %) followed by T.. atomaria (0.71%) and G. cylindriea (0.61%). The minimum phosphorus content was observed in U. fasciata (0.11%) ...
... Total Phosphorus content of marine algal phospholipids fraction was presented in Table (1). The results showed that the maximum content was observed in D. fasciola (0.86 %) followed by T.. atomaria (0.71%) and G. cylindriea (0.61%). The minimum phosphorus content was observed in U. fasciata (0.11%) ...
Candidate Vaccine Neisseria meningitidis a to Genome
... cacious in humans for prevention of group B disease (reviewed in Ref. 5), but the bactericidal Abs tend to be strain specific and are directed predominantly at PorA (16). The utility of these vaccines, therefore, is limited by extensive antigenic diversity of the surfaceaccessible loops of PorA (17, ...
... cacious in humans for prevention of group B disease (reviewed in Ref. 5), but the bactericidal Abs tend to be strain specific and are directed predominantly at PorA (16). The utility of these vaccines, therefore, is limited by extensive antigenic diversity of the surfaceaccessible loops of PorA (17, ...
Roles of Naturally Occurring Bacteria in Controlling Iodine
... isolated from an 129I contaminated aquifer (F-area of the Savannah River Site, SC) on Ioxidation and OI formation. It was demonstrated that 3 of 136 strains accumulated I- (0.2~2%) in the presence of H2O2, when incubated in the presence of an environmentally relevant concentration of I- (0.1 μM). Th ...
... isolated from an 129I contaminated aquifer (F-area of the Savannah River Site, SC) on Ioxidation and OI formation. It was demonstrated that 3 of 136 strains accumulated I- (0.2~2%) in the presence of H2O2, when incubated in the presence of an environmentally relevant concentration of I- (0.1 μM). Th ...
RefectoCil Eyelash Perm
... wonderful curl, letting the eyes appear lager and more expressive. At the same time the eyelashes are nourished. Unlike mechanical lash curlers RefectoCil Eyelash Perm gently forms the eyelashes with the curl lasting up to 6 weeks. Collagen is one of the commonly occurring structural proteins in the ...
... wonderful curl, letting the eyes appear lager and more expressive. At the same time the eyelashes are nourished. Unlike mechanical lash curlers RefectoCil Eyelash Perm gently forms the eyelashes with the curl lasting up to 6 weeks. Collagen is one of the commonly occurring structural proteins in the ...
Biochemical Similarity of Expressed Human Prorenin
... renin is synthesized as a 55,000-molecular-weight inactive form, which is then converted to a 44,000-molecular-weight active renin.6 However, when cells from this tumor were cultured, the 55,000 form was exclusively released into the medium, and no conversion to the smaller form occurred. Galen et a ...
... renin is synthesized as a 55,000-molecular-weight inactive form, which is then converted to a 44,000-molecular-weight active renin.6 However, when cells from this tumor were cultured, the 55,000 form was exclusively released into the medium, and no conversion to the smaller form occurred. Galen et a ...
Purification and Characterization of Extracellular and
... toxin does not occur. It is likely that the cytoplasmic inheritance of the killer toxin of S. cerevisiae depends on the presence of two different double-stranded molecules of RNA (dsRNA) that are localized in virus-like particles in the cytoplasm (Young & Yagiu, 1978; Bussey, 1981). The smaller of t ...
... toxin does not occur. It is likely that the cytoplasmic inheritance of the killer toxin of S. cerevisiae depends on the presence of two different double-stranded molecules of RNA (dsRNA) that are localized in virus-like particles in the cytoplasm (Young & Yagiu, 1978; Bussey, 1981). The smaller of t ...
Organic Acid
... Organic acids are used in food preservation because of their effects on bacteria. The key basic principle on the mode of action of organic acids on bacteria is that non-dissociated (non-ionized) organic acids can penetrate the bacteria cell wall and disrupt the normal physiology of certain types of ...
... Organic acids are used in food preservation because of their effects on bacteria. The key basic principle on the mode of action of organic acids on bacteria is that non-dissociated (non-ionized) organic acids can penetrate the bacteria cell wall and disrupt the normal physiology of certain types of ...
New Host Plants of Erwinia amylovora in Bulgaria
... and indole formation. Some variability was detected among the strains from chokeberry in acid production from inositol. They were separated on the base of this property into two groups Ð positive and negative (Table I). It should be noted that the strains from these two groups were isolated from dif ...
... and indole formation. Some variability was detected among the strains from chokeberry in acid production from inositol. They were separated on the base of this property into two groups Ð positive and negative (Table I). It should be noted that the strains from these two groups were isolated from dif ...
Mammalian CSAD and GADL1 have distinct biochemical properties
... taurine may modulate protein phosphorylation (Lombardini, 1994), serve as a trophic factor (Hernandez-Benitez et al., 2010; PasantesMorales and Hernandez-Benitez, 2010), or act as a neurotransmitter/neuromodulator (Jia et al., 2008). In several species, taurine deficiency has been linked to specific d ...
... taurine may modulate protein phosphorylation (Lombardini, 1994), serve as a trophic factor (Hernandez-Benitez et al., 2010; PasantesMorales and Hernandez-Benitez, 2010), or act as a neurotransmitter/neuromodulator (Jia et al., 2008). In several species, taurine deficiency has been linked to specific d ...
SAKE Alcoholic Beverage Production in Japanese Food
... Fermentative multi-budding yeast, Saccharomyces cerevisiae, which has been used not only in SAKE brewery, but also in beer brewry, winery and bakery, was discovered in ca. 1830 by J. Meyen; it was named by E.C. Hansen in 1882 [5]. SAKE yeast is classified taxonomically in the Saccharomyces cerevisia ...
... Fermentative multi-budding yeast, Saccharomyces cerevisiae, which has been used not only in SAKE brewery, but also in beer brewry, winery and bakery, was discovered in ca. 1830 by J. Meyen; it was named by E.C. Hansen in 1882 [5]. SAKE yeast is classified taxonomically in the Saccharomyces cerevisia ...
Suppression of Hepatic XBP1s Decreases the Bile Salt Pool
... essential for everyday bodily functions. In the liver, they are important metabolic regulators that account for biliary secretion of lipids and intestinal nutrient absorption as well as signaling factors responsible for maintaining homeostasis within the organism [29]. The enterohepatic system relie ...
... essential for everyday bodily functions. In the liver, they are important metabolic regulators that account for biliary secretion of lipids and intestinal nutrient absorption as well as signaling factors responsible for maintaining homeostasis within the organism [29]. The enterohepatic system relie ...
Kinetics of Peroxynitrite Reaction with Amino Acids and Human
... To better understand the mechanisms of peroxynitrite cytotoxicity and its role in pathological processes, it is important to characterize its reactivity toward different biomolecules. In this sense, proteins are key targets of oxidative stress. Exposure to oxidants such as hydrogen peroxide leads to ...
... To better understand the mechanisms of peroxynitrite cytotoxicity and its role in pathological processes, it is important to characterize its reactivity toward different biomolecules. In this sense, proteins are key targets of oxidative stress. Exposure to oxidants such as hydrogen peroxide leads to ...
... particular immunological compositions and vaccines, hereunder nucleotide-based vaccines comprising these compounds. In addition, the invention provides the use of the compounds mentioned for the manufacture of compositions, such as immunogenic compositions. Other aspects of the invention relates to ...
Recent Progress in Electrochemical HbA1c Sensors: A Review
... The HbA1c sensors reported by Yoon et al. [40,41] relied on GOx-catalyzed oxidation of glucose, in which H2O2 is produced as a reaction product. The pTTBA/AuNPs-based HbA1c sensors acquired output signals in the presence of H2O2 [42]. Consequently, careful attention was required to detect possible c ...
... The HbA1c sensors reported by Yoon et al. [40,41] relied on GOx-catalyzed oxidation of glucose, in which H2O2 is produced as a reaction product. The pTTBA/AuNPs-based HbA1c sensors acquired output signals in the presence of H2O2 [42]. Consequently, careful attention was required to detect possible c ...
Full-Text PDF
... In addition, a known amount of melittin (5 µg/mL) was added to stratum corneum, epidermis, and dermis of the rat skin, and the amount of melittin was measured at pre-determined time points. The measurement of melittin from all samples was done with HPLC-MS/MS. No melittin was detected in the recepto ...
... In addition, a known amount of melittin (5 µg/mL) was added to stratum corneum, epidermis, and dermis of the rat skin, and the amount of melittin was measured at pre-determined time points. The measurement of melittin from all samples was done with HPLC-MS/MS. No melittin was detected in the recepto ...
Storage lipids of yeasts: a survey of nonpolar lipid metabolism in
... defects in these processes are related to severe human diseases. The baker’s yeast Saccharomyces cerevisiae has become a valuable tool to study eukaryotic lipid metabolism because this single-cell microorganism harbors many enzymes and pathways with counterparts in mammalian cells. In this article, ...
... defects in these processes are related to severe human diseases. The baker’s yeast Saccharomyces cerevisiae has become a valuable tool to study eukaryotic lipid metabolism because this single-cell microorganism harbors many enzymes and pathways with counterparts in mammalian cells. In this article, ...
Amines and Amides
... 1939), who observed the antibacterial action of the red dye Protonsil; further researched showed that it was the metabolic byproduct, sulfanilamide, which was the active form. It prevents bacteria from synthesizing folic acid, which they need in order to grow. Bacterial enzymes synthesize folic acid ...
... 1939), who observed the antibacterial action of the red dye Protonsil; further researched showed that it was the metabolic byproduct, sulfanilamide, which was the active form. It prevents bacteria from synthesizing folic acid, which they need in order to grow. Bacterial enzymes synthesize folic acid ...
The Hype on the Endothelin Signaling System Muscarinic Receptor
... subjected by a severe light insult (consequently leading to retinal degeneration) and monitoring changes in gene expression21. Microarray analysis was performed on retinas damaged by acute exposure to visible light (known to also lead to photoreceptor death). Genes that were upregulated include ET-2 ...
... subjected by a severe light insult (consequently leading to retinal degeneration) and monitoring changes in gene expression21. Microarray analysis was performed on retinas damaged by acute exposure to visible light (known to also lead to photoreceptor death). Genes that were upregulated include ET-2 ...
Membrane transporters in a human genome-scale
... The first GENRE for human metabolism, Recon 1 (Duarte et al., 2007), captured the biochemical transformations occurring in cells in a stoichiometrically accurate manner. These reactions are distributed over seven intracellular compartments (i.e., cytoplasm, mitochondrion, Golgi apparatus, endoplasm ...
... The first GENRE for human metabolism, Recon 1 (Duarte et al., 2007), captured the biochemical transformations occurring in cells in a stoichiometrically accurate manner. These reactions are distributed over seven intracellular compartments (i.e., cytoplasm, mitochondrion, Golgi apparatus, endoplasm ...
The Role of Carnitine System in Maintaining Muscle Homeostasis
... at the basis of a metabolic phenotype in which type I muscle fibers predominate. Contractile properties of the fatigue resistant, slow-twitch oxidative type I fiber is molecularly distinguished by the myosin heavy chain (MHC) I isoform. This impacts on the partitioning of lipids towards oxidation in ...
... at the basis of a metabolic phenotype in which type I muscle fibers predominate. Contractile properties of the fatigue resistant, slow-twitch oxidative type I fiber is molecularly distinguished by the myosin heavy chain (MHC) I isoform. This impacts on the partitioning of lipids towards oxidation in ...
The shikimate pathway in apicomplexan parasites: Implications for
... finally attack of the carbanion at the C-1 keto function to close the ring to yield 3-dehydroquinate (5). The transient oxidation-reduction reaction is performed by NAD+. In addition DHQS requires either Co2+ or Zn2+ to assist catalysis (24, 25). The N-terminal domain of DHQS contains a Rossmann fol ...
... finally attack of the carbanion at the C-1 keto function to close the ring to yield 3-dehydroquinate (5). The transient oxidation-reduction reaction is performed by NAD+. In addition DHQS requires either Co2+ or Zn2+ to assist catalysis (24, 25). The N-terminal domain of DHQS contains a Rossmann fol ...
Ammonium toxicity and potassium limitation in yeast.
... the great challenges faced by microorganisms. This maintenance of metabolic homeostasis is achieved largely by controlling the activities and concentrations of enzymes and transporters. One important means of controlling enzyme concentrations is transcriptional regulation [1–3]. In the wake of the g ...
... the great challenges faced by microorganisms. This maintenance of metabolic homeostasis is achieved largely by controlling the activities and concentrations of enzymes and transporters. One important means of controlling enzyme concentrations is transcriptional regulation [1–3]. In the wake of the g ...
Hepoxilin
Hepoxilins (HxA3 and HxB3) are nonclassic eicosanoid hormones involved in inflammation.