Download Hardy Weinberg Questions

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Hardy-Weinberg Questions
Problem 1:
1 in 1700 US Caucasian newborns have cystic fibrosis. C for normal is dominant over c
for cystic fibrosis.
a) What percent of the above population have cystic fibrosis (cc or q2)?
b) From the above numbers you should be able to calculate the expectant
frequencies of all the following (assuming a Hardy-Weinberg equilibirum):
a. Calculate q
b. Calculate p
c. Find the genotype frequencies for homozygous dominant and
heterozygous
c) How many of the 1700 are homozygous normal?
d) It has been found that a carrier is better able to survive diseases with severe
diarrhea. What would happen to the frequency of the "c" if there was an epidemic
of cholera or other type of diarrhea producing disease?
Problem 2:
If 9% of an African population is born with a severe form of sickle-cell anemia (ss), what
percentage of the population will be more resistant to malaria because they are
heterozygous (Ss) for the sickle-cell gene? (Show your working)
Problem 3:
After graduation, you and 19 friends build a raft, sail to a deserted island, and start a
new population, totally isolated from the world. Two of your friends carry (that is, are
heterozygous for) the recessive cf allele, which in homozygotes causes cystic fibrosis.
a) Assuming that the frequency of this allele does not change as the population
grows, what will be the instance of cystic fibrosis on your island?
b) Cystic fibrosis births on the island is how many times greater than the original
mainland. The frequency of births on the mainland is .059%.