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Learning Issues:
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Chronic- long term (longer than 2 weeks)
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Acute- short term (less than 2 weeks)
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What are Pet Tabs?
Scored tablets containing 18 essential vitamins and minerals. Daily dietary supplement.
Are Airplane Plants or Cast Iron Plants dangerous or poisonous to dogs?
Both are safe, non toxic plants for pets and people.
What are the vaccines given in Washington, and how do they differ from typical Louisiana vaccinations?
DA2PL – distemper, adenovirus 2, parainfluenza, leptospirosis.
             CPV – canine parvovirus, Rabies
– Core vaccines at Washington State are DA2PP and Rabies, nothing found for Louisiana.
                 ***Leptospirosis can cause kidney.
Diseases from Washington State include Salmon Poisioning.
Salmon Poisoning Disease is a potentially fatal condition seen in dogs that eat certain types of raw fish. Salmon (salmonid fish) and
other anadromous fish (fish that swim upstream to breed) can be infected with a parasite called Nanophyetus salmincola. Overall,
the parasite is relatively harmless. The danger occurs when the parasite itself is infected with a rickettsial organism called
Neorickettsia helminthoeca. It’s this microorganism that causes salmon poisoning.Â
“Salmon poisoning occurs most commonly west of the Cascade mountain range,” says Dr. Bill Foreyt, a veterinary
parasitologist at Washington State University’s College of Veterinary Medicine. He adds, “Canids (dogs) are the only species
susceptible to salmon poisoning. That’s why cats, raccoons and bears eat raw fish regularly with out consequence.”Â
Generally clinical signs appear within six days of a dog eating an infected fish.Â
Common symptoms of salmon poisoning include:
Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â vomiting
Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â lack of appetite
Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â fever
Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â diarrhea
Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â weakness
Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â swollen lymph nodesÂ
Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â dehydration
If untreated, death usually occurs within fourteen days of eating the infected fish. Ninety percent of dogs showing symptoms die if
they are not treated.
What is the purpose of a dog eating grass?
Found a lot of theories, doesn’t seem relevant. (Upset stomach, nutritional deficiency)
What are common diseases in Cocker Spaniels?
Progressive retinal atrophy, glaucoma, cataracts, autoimmune diseases including autoimmune hemolytic anemia, autoimmune
thyroiditis, hypothyroidism, skin problems, luxating patellas and hip dysplasia.
What are possible dangers of not spaying?
Diseases of female reproductive system, Pyometria, Uterine rupture, acute nephritis, cystic endometrial hyperplasia, uterine
aplasia, uterine prolapse, cystic ovarian disease, vaginitis, vaginal hyperplasia. Mastitis and mammary tumors.
Define the normal estrous cycle:
4 stages: proestrus, estrus, diestrus, anestrus, estrus occurs twice a year. Estrus averages nine days but can be as short as 3
days. First 9 days proestrus, next 9 days estrus, those two make up “Heat” then 60 days of diestrus or pregnancy then 90 to
150 days of anestrus, those two together make up interestrus.
What is the nutritional content of Science Diet Light cat food; does it contain anything that would be harmful to dogs?
Is there any possibility of acclimatization problems?
This is mainly a problem in horses. Chronic heat stress can look like adrenocorticism or Addison’s disease.Â
What is Adrenocorticism?
A deficiency in adrenal cortisol hormone common in middle aged dogs. Primary cause not known. Possibly autoimmune. Most
common in young adult female dogs.
Is there a way to distinguish between lethargy associated with normal aging and lethargy caused by a disease?
Aging causes a dog to slow down, sleep more, etc ; common underlying causes: arthritis, scenility, obesity, vision/hearing loss.
Many ailments can cause lethargy as well, like hypothermia, fever, endocrine disorders, hypoglycemia, malnutrition or toxins.
Probably the best way to determine if lethargy is associated with other emergent clinical signs is to obtain a detailed history of the
particular dog’s normal behavior before its illness.Â
What is the normal TPR, weight?: T- 102 plus or minus 1, HR= 70-120, RR = 18-34, 15-30 lbs.
Heartworms: Heartworms reach maturity at 6-7 mos and start shedding antigens into the dog’s bloodstream; Signs: General
lethargy, loss of condition, decreased stamina, exercise intolerance, prolonged recovery time, shortness of breath, and coughing
-Can cause renal damage – immune complex glomerular disease (proteinuria)
-HW + animals can have elevated ALT and ALP values
-Urinalysis may reveal proteinuria that can be semiquantitated by a urine protein:creatinine ratio
Diabetes symptoms: Normal fasting value for blood glucose in dogs is 75-120 mg/dLÂ Clinical findings: Polydipsia, polyuria,
polyphagia with weight loss, bilateral cataracts, and weakness. Diabetic animals have decreased resisitance to bacterial/fungal
infections and often develop chronic or recurrent infections such as: cystitis, prostatitis, bronchopneumonia, and dermatitis.
Hepatomegaly (fatty liver) is also common in diabetic animals
Chemistry Panel:
Â Â Â Â Â Â Â Â Â Blood Glucose (GLU) - High levels can help diagnose diabetes and can
indicate stress, excess of the hormone progesterone, an overactive adrenal gland. Low levels
can indicate liver disease, tumors or abnormal growth on pancreas, an underactive adrenal
gland.
o        Blood Urea Nitrogen (BUN) - BUN is produced by the liver and excreted by the
kidneys. Decreased levels are seen with low protein diets, liver insufficiency, and the use of
anabolic steroid drug. Increased levels indicate any condition that reduces the kidney's ability
to filter body fluids in the body or interferes with protein breakdown.
o        Creatinine (CREA) - Creatinine is a by-product of muscle metabolism and is
excreted by the kidneys. Elevated levels can indicate kidney disease or urinary obstruction,
muscle disease, arthritis, hyperthyroidism, and disbetes. An increased BUN and normal
creatinine suggest an early or mild problem. An increased creatinine and increased BUN with
elevated phosphorus indicate a long standing kidney disease.
o        Total Protein (TP) - Increases indicate dehydration or blood cancer, bone marrow
cancer; decreases indicate malnutrition, poor digestion, liver or kidney disease, bleeding or
burns.
o        Albumin (ALB) - Produced by the liver, reduced levels of this protein can point to
chronic liver or kidney disease, or parasitic infections such as hookworm. High levels indicate
dehydration and loss of protein.
o        Calcium (CA) - Blood calcium levels are influenced by diet, hormone levels and
blood protein levels. Decreased levels indicate acute damage to the pancrease or undersctive
parathyroid. Muscle twitches may occur in decreased level. Increased levels can be an
indicator of certain types of tumors, parthyroid or kidney disease. Dr. Goldstein mentioned in
his book, Nature of Animal Healing that low calcium level may indicate deficiency of pancreatic
enzymes, and high calcium level may indicate poor metabolism of fats and protein.
o        Phosphorus (PHOS) - Affected by diet, parathormone and kidney. Decreased levels
shows overactive parathyroid gland and malignancies, malnutrition and malabsorption.
Increases with underactive parathyroid gland and kidney failure.
o        Cholesterol (CHOL) - Decreased levels are found in an overactive thyroid gland,
interstinal malabsorption. Elevated levels of cholesterol are seen in a variety of disorders
including hypothyroidism and diseases of the liver, kidneys, cardiovascular, diabetes, stress.
o        Total Billirubin (TBIL) - A component of bile, bilirubin is secreted by the liver into
the intestinal tract. High levels can lead to jaundice and indicate destruction in the liver and
bile duct.
o        AST – aspartate aminotransferase, dects liver damage
o        Alanine aminotransferase (ALT) - An enzyme that becomes elevated with liver
disease.
o        Alkaline Phosphatase (ALKP) - An enzyme produced by the biliary tract (liver).
High levels indicate bone disease, liver disease or bile flow blockage.
o        GGT – gamma-glutamyl transpeptidase; screens for liver disease
o        CPK – creatine phosphokinase
o        Sodium & Potassium - levels affected in diseases of the adrenal glands, heart,
kidneys, or various medications. Changes in their levels can lead to secondary problems
like preventing the heart, nerves, and kidneys from functioning correctly.
o        Chloride - electrolyte
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What is ALP? Alkaline Phosphatase removes phosphate groups. Elevated ALP values can indicate bone deposition, liver damage, and
biliary tract disease
What is ALT? Alanine Aminotransferase is involved in the degradation and synthesis of amino acids. Elevated ALT values can
indicate liver disease and toxic damage to liver or muscle damage.
What is a lipoma? Sebaceous Adenoma? Lipomas are common benign tumors of well-differentiated adipocytes. They may contain
collagen (fibrolipoma) or blood vessels (angiolipomas). They are common in dogs, especially females. Commonly found:
Subcutaneous, in trunk, gluteal, proximal limbs. They are well-circumscribed, encapsulated, and freely movable. A small percentage
are infiltrative, still benign. They are slow-growing.
-Sebaceous Adenomas are very common in dogs and involve sebocytes with few basaloid reserve cells and ducts. Their peak
incidence is in 8-13 yrs. Cockers have increased risk. They are multilobulated, mostly exophytic (grow outside), some invasive
component into dermis and subcut. Tissue. They can ulcerate with secondary infection but are benign and should be removed
surgically.
What is a nuclear sclerosis?
Nuclear sclerosis is a normal occurrence in the lenses of older dogs. It appears as a grey miscoloration of the lens. It usually occurs in
both eyes at the same time and is common in dogs over 6 years of age. The loss of transparency occurs b/c of compression of the
linear fibers of the lens. The condition does not significantly affect the vision of the dog, and treatment is not recommended.
What is her body condition score and what does this mean? Body condition scores give a numerical value to a dog’s overall
muscle/fat condition. The scales may range from 1 (emaciated) to 5 or 9 (very obese). “Brandi” would be a 5 (or 9
depending on scale) meaning she is very obese.
What is “sanguineous”? Bloody, abounding in blood (Blood, Saunders Dictionary)
What is the normal capillary refill time (CRT) in a dog? <2
What is Pyometra? Acute infection that is regardless of age in bitches. High risk period right after bitch goes into heat. Should be
treated as a medical emergency if suspected. Signs: Fever, lethargy, loss of appetite, excessive thirst, enlarged vulva,
hyperproteinemia, and other indicators of sickness. Main risk period is 8 weeks after her peak standing heat (estrus cycle). Normally
during this period, the cervix is beginning to close and the inner lining begins to adapt back to normal. However, cystic hyperplasia
of the endometrium may occur at this time as an inappropriate response to progesterone. Under these circumstances bacteria
(especially e. coli) that have migrated from the vagina into the uterus find the environment favorable to growth. Bloodwork may
show dehydration, increased white blood cell count and increased alkaline phosphatase. X rays will show an enlarged uterus and
ultrasound will confirm the presence of a fluid filled uterus.
What are problems associated with feeding dogs table scraps?
Dogs can eat table scraps under certain conditions, which do not alter their normal consumption of a well balanced meal. They
require a consistent diet and such alterations may result in several health and behavioral problems. Table scraps do not provide the
nutrition that dog’s need. Dogs that are fed table scraps frequently tend to be overweight and therefore are at greater risk for
developing cardiovascular diseases. Sudden changes in some dog's diet may promote diarrhea, vomiting and in the instance of
providing too much fat all of a sudden, pancreatitis. Pancreatitis is known as an inflammation of the pancreas caused by leakage of
active digestive enzymes into the pancreatic tissue. When this occurs these enzymes start to digest the pancreas itself, and can
affect the liver, small intestine, and stomach and cause widespread damage to the abdomen. Clinical signs seen in many dogs
affected with pancreatitis include abdominal pain, depression, and decreased appetite. Vomiting and diarrhea may be seen as well.
In severe cases there may be signs of shock or total collapse.  High fat diets, especially in combination with low protein intake,
appear to contribute to the development of pancreatitis. A single high fat meal may cause pancreatitis in a pet whose normal diet is
moderate or low in fat.
Lyme Disease Issues
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Urine formation – trace a drop of water from the bowl to the puddle.
What are the four steps of urine formation in the kidney?
1)      Filtration 2)  Reabsorption 3)  Secretion 4)  Excretion
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How is blood filtered through the kidney?
                          About 25% of cardiac output is sent to the kidneys for filtration. In the kidney,
filtration occurs across the wall of capillary networks called glomeruli. Afferent arterioles split into tufts of glomerular capillaries
to control the rate and selectivity of the filtration process. The endothelium of the capillaries is fenestrated and covered by a
glomerular basement membrane. The fenestrae allow the passage of water and non-cellular components from the blood into the
space surrounding a glomerulus, Bowman’s space. The basement membrane includes several glycoprotein layers, including the
outermost layer of podocytes, fingerlike projections wrapping around the capillaries. There are several selective processes that
determine what is filtered through the capillary wall. Normally, only molecules smaller than 4 nm in radius can pass into
Bowman’s space. Also, the glycoprotein layers cause cations to be filtered much more easily than their anionic
counterparts. Some shapes of molecules filter out of the blood more readily as well. Plasma proteins are retained in the
capillaries. The fluid that is collected in Bowman’s Space is called Glomerular filtrate, and is similar to plasma. The rate of
glomerular filtration can be evaluated, giving a numeric value, the GFR in mL/min/kg. The rate depends on mean net filtration
pressure. This is the pressure difference between the blood and Bowman’s Space. The main determinant in this pressure is
the hydrostatic pressure of the blood. Bowman’s space is relatively low pressure, because none of the proteins cross the
capillary barrier. The permeability of the capillary wall and the area available for filtration are other factors in filtration. The
renin-angiotensin-aldosterone system is one way in which the body regulates the GFR by hormonal regulation of renal blood
flow. Renin is a hormone produced in the mesangial cells of the afferent arteriole, which is released when the kidneys are not
being properly perfused. It converts angiotensinogen to Angiotensin I, which is further converted to Angiotensin II by Angiotensin
converting enzyme. Angiotensin II is a potent vasoconstrictor, so it causes a blood pressure increase. It also causes the release of
aldosterone and vasopressin, which affect salt and water retention and intravascular volume. Prostaglandin E2 and prostaglandin
I2, two renal vasodilators, are released as a control over the angiotensin’s effects. There is also tubuloglomerular feedback, in
which the sensitive macula densa cells detect high NaCl levels and release factors to inhibit renin release in the adjacent mesangial
cells of the same nephron. The capillary endothelium also exerts some hormone control of blood pressure. Basically any
modification of blood pressure in the kidney will affect the GFR.
After the glomerular filtrate enters the renal tubules, it flows sequentially through the proximal tubules, loops of Henle, distal
tubules, collecting tubules, and collecting ducts before it is excreted as urine.
What is reabsortion in the kidney and how does it take place?
Â Â Â Â Â Â Â Â Â Reabsorption: Moving filtered material from the lumen of the nephron back to the blood as it flows
through the peritubular capillaries. 99% of what is filtered needs to be reabsorbed! This occurs in the renal tubules,
primarily (60%) in the proximal tubule.
o        Movement of tubule fluid occurs in 2 ways here: 1) transcellular pathway, and 2) paracellular
pathway.
Â Â Â Â Â Â Â Â Â The transcellular pathway fluid flows via a carrier-mediated transport (active)
mechanism through the epithelial cells of the proximal tubule into the interstitial fluid on the blood
side of the cells.
Â Â Â Â Â Â Â Â Â The paracellular pathway allows substances to passively diffuse from tubule fluid
through tight junctions on the epithelial cells to the interstitial fluid.
Â Â Â Â Â Â Â Â Â Urea is reabsorbed along a concentration gradient that is formed by sodium and water
being reabsorbed first.
Â Â Â Â Â Â Â Â Â Most plasma proteins are too large to be filtered, but some smaller proteins,
hormones, and enzymes can pass through the filtration barrier and are then reabsorbed in the
proximal tubule. Proteins too large to be reabsorbed through channels/carriers can be taken up by
endocytosis.
o        The distal tubule segments include the thick ascending limb of Henle’s loop and the distal
convoluted tubule. These segments reabsorb salts and dilute the tubule fluids based on their different
permeabilities.
o        The collecting duct reabsorbs NACL and can secrete or reabsorb Potassium
o        Starling’s Forces between the interstitium and the bloodstream favor uptake of fluids and solutes
back into the bloodstream, thus reabsorption has occurred.
What is secretion in the kidney and how does it take place?
Â Â Â Â Â Â Â Â Â Secretion: an active process that moves substances against their concentration gradients. Secretion
enables the nephron to enhance excretion of a molecule.
o        The proximal tubule also plays a part in secreting organic ions from the blood into the tubule fluid by
a carrier-mediated process.
How does excretion take place?
Â Â Â Â Â Â Â Â Â Peristaltic contractions of the ureters, which are initiated by parasympathetic stimulation, take place.
These contractions force the urine from the renal pelvis to the urinary bladder.
Â Â Â Â Â Â Â Â Â The bladder is made up of smooth muscle called detrusor muscle.
o        As the fibers of the detrusor muscle contract these cause the bladder to empty.
Â Â Â Â Â Â Â Â Â The posterior urethra, also known as the neck of the bladder, also contains detrusor muscle as well as
elastic tissue and an internal sphincter. The sphincter keeps the bladder from emptying un...
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