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Hematology Power-point (April 7, 2015)
Functions of the Blood
Transports _______________________________________________________
Aids in distribution __________________________
Regulates _________________________________
Helps ________________________________________________________
Composition
Plasma – _______________________________________________________
Serum
Plasma ________________________________________________________
Components
Cellular ________________________________________________________
Plasma
Straw _________________________________________
W_____________
Bl___________________________________________
___________________________________________
El____________________
Hormones, ___________________________________
M__________________________________________
Straw colored and contains Water
Blood proteins
Nutrients
Electrolytes
Hormones, vitamins, enzymes
Metabolic waste products
Fibrinogen____________________________________________________________________________
___________________________________________________________
Albumin______________________________________________________________________________
___________________________________________________________
Prothrombin _____________________________________________________________
________________________________________________________________________
________________________________________________________________________
Erythrocytes
Shape ___________________________________________________Hemoglobin- gives red color, _________ is iron and __________ is protein,
Function – ___________________________________________________________
Normal – men ____________________
Women – _____________ gm
Functions of Hemoglobin
Red cells travel ___________________________________________________________
________________________________________________________________________
________________________________________________________________________
Arterial blood – __________________________________________________________
Venous blood – __________________________________________________________
Carbon Monoxide Poisoning
CO is a __________________________________________________________________
________________________________________________________________________
CO interferes ____________________________________________________________
O2 is ___________________________________________________________________
Erythropoiesis
_______________________________________
 Occurs in bone marrow.
Red cells _____________________________
Old cells ____________________________ Hemolysis
White Blood Cells
 Larger than ______________________________
 G______________________________________
 5 _________________
 Normal leukocyte count = 3,200 – 9,800
 _________________- when WBC have the ability to squeeze through the intercellular
spaces of capillary walls to fight infection in neighboring tissues.
 Neutrophils
 Granuloccyte___________________________________
 _____________________________________________
 Eosinophils
 _____________________________________
 Formed in the _________________________
 Increase in numbers __________________________________________________
 Basophils
 Produce__________________________________________________
 Granulocyte Count ____________________________________________________
____________________________________________________________________
 Lymphocytes
 ________________________________absence of cytoplasmic granules formed in
lymph glands, nodes and bone marrow. B-lymphocytes and T-lymphocyte Protect
against cancer cells.
 Monocytes
 Assist in ______________________________________________________________
_____________________________________________________________________
_____________________________________________________________________
 A ____________________________________________________________________
 Phagocytosis – _________________________________________________________
______________________________________________________________________
 Abscess
 ______________________________________________________________________
 Pyrexia
 _______________________________________________________________________
_______________________________________________________________________
 Leukocytosis
_______________________________________________________________________
 Leukopenia
 Decrease in ______________________________________________________________
________________________________________________________________________
Thrombocytes
 Smallest of __________________________________________________
 Synthesized in _____________________________________
 Not cells fragments of megakaryocytes
 Necessary for the_____________________________________________________
 Coagulation
 Cut or injuryplatelets and injured tissue release __________________act on
_______________ in plasma+ Calcium ions converts to _______________the
thrombin acts as an enzyme and changes ____________________________ creating
a mesh that traps red blood cells, platelets and plasma creating a blood clot.
 Anticoagulants prevent __________________
 Heparin __________________________
 Prothrombin dependent on _____________________
Blood Types
____________________ types of blood.
•
________________________________
•
_______________from parents.
•
Determined by presence or absence of an ____________ on the surface of the red
blood cell
•
Blood protein
•
Located on the _________________________________________________
•
Either the person _______________________________________________
•
Someone with type A blood have the A antigen, Someone with type B blood have the B
antigen, type AB has both A and B antigen, and type O has neither of the antigens
•
Someone with type A blood has__________________________
•
Someone with type B blood has __________________________
•
Someone with type AB blood has _________________________
•
Someone with type O blood has __________________________
•
Antibody –______________________________________________________________
_______________________________________________________________________
•
Red cells may contain RH Factor
•
If you have it, ________________________
•
If you don’t, _________________________
•
When an Rh- mother is pregnant with an Rh+ baby, the baby’s blood (usually during
delivery) can mix with the mom’s blood, causing the mom’s blood to make anti Rh
antibodies.
•
If the mom gets pregnant again with another Rh+ positive baby, her anti Rh antibodies
will attack the baby’s blood, causing_____________________________________
•
RHO Gam will destroy any baby blood cells in the mom, and her immune system won’t
produce antibodies.
•
_______________________________________________is easy to transplant, and does
not cause rejection That is why research is being done on umbilical cord blood.
•
Disorders of the Blood
•
Anemia
•
__________________________________________________________
•
Iron Deficiency Anemia
•
Usually in_____________________________________________________
•
Deficiency of__________________________________insufficient hemoglobin synthesis
•
Treat with ___________________________________________________________
Polycythemia
•
_________________________________ cells are formed.
•
May be a temporary condition _____________________________________
•
Aplastic Anemia
•
____________________ does not produc__________________________________
•
Caused by ________________________________________________________
Sickle Cell Anemia
Chronic blood disease
_______________________________________________________
Causes the red cells to form in_____________________________________________
Sickle cells break easily and ______________________________________________
Occurs primarily in ____________________________________________________
Treatment – _______________________________________
Embolism
•
Air, blood clot , cancer cells, fat, etc. that is _______________________________
__________________________________Also known as a
____________________________________________________________
•
Thrombus
•
The formation of a ___________________________________________
•
The blood clot is___________________________________
Hematoma
•
Localized ________________________________________ in an organ tissue or space.
Caused by an ___________________________________________________________
Hemophilia
•
Hereditary
•
M_____________________________________________________________
•
Blood clots _____________________________________________________
•
Sex linked – transmitted ________________________ from_______________________
•
Treat with missing clotting factor, ____________________________
Thrombocytopenia
•
Not ____________________________________________________________
•
Blood will _______________________________________________________
•
Leukemia
•
Malignant _______________________________________
•
Overproduction of ______________________________________________________
•
Research ________________________