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Chapter 12 What confounding problems could have been seen if Mendel had chosen another plant with exposed male and female structures? (Figure 12.3) Answer: The ability to control whether the plants self-fertilized or cross-fertilized was of paramount importance in Mendel’s studies. Results due to cross-fertilization would have had confounding influences on the predicted number of offspring with a particular phenotype. If one of the affected females in the third generation married an unaffected male, could she produce unaffected offspring? If so, what are the chances of having unaffected offspring? (Figure 12.8) Answer: Each of the affected females in the study had one unaffected parent, which means that each is heterozygous for the dominant trait. If each female marries an unaffected (recessive) male, each could produce unaffected offspring. The chance of having unaffected offspring is 50% in each case. From a genetic disease standpoint, why is it never advisable for close relatives to mate and have children? (Figure 12.9) Answer: Genetic defects that remain hidden or dormant as heterzygotes in the recessive state are more likely to be revealed in homozygous state among closely related individuals. Many studies of identical twins separated at birth have revealed phenotypic differences in their development (height, weight, etc.). If these are identical twins, can you propose an explanation for these differences? (Page 233) Answer: Almost certainly, differences in major phenotypic traits of twins would be due to environmental factors such as diet.