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DNA WebQuest NAME___________________________ Topic: Replication and Protein Synthesis A. Go to: http://www.pbs.org/wgbh/aso/tryit/dna/shockwave.html B. Click: DNA Replication (upper left) and then click unzip C. Read the What Happened box, answer the questions below, and then, click 1. In a real cell, what does the DNA molecule do before it unzips? 2. What molecules break the rungs (bases) apart? ok D. Drag the correct bases over to “synthesize” the new DNA halves. You have to drag bases to both sides of the DNA strand. If you try to put the incorrect bases together, it will not let you. (Remember A – T, C – G) E. Read the What Happened box , answer questions, and then click 3. F. Click ok How many base pairs are in the real human genome? Protein Synthesis (upper right). Click unzip G. Read the What Happened box, answer the questions below, and then, click 4. ok How much of the DNA molecule actually unzips in a real cell? H. Base pair the nucleotides for just one half of the DNA. (Just like you did before with dragging over the base pairs to the DNA molecule, this time A-U, C-G) J. Read the What Happened box, answer the questions below, and click ok 5. About how many bases would a real mRNA molecule have? 6. Where does the mRNA go now? **Exit out of this webpage** Topic: Protein Synthesis A. Go to: http://www.wisc-online.com/objects/index_tj.asp?objid=AP1302 B. Read the animation page by page – scroll down to the white box towards the middle of the webpage that says “Protein Synthesis”. ready to move on. Just click the button when you are 1. How does the mRNA leave the nucleus? (4th slide) 2. Is just one mRNA molecule made? (4th slide) According to what? 3. How many amino acids does each codon code for? (slide 6) **Exit out of this webpage** Topic: Mutations A. Go to: http://www.web-books.com/MoBio/Free/Ch7E.htm B. Read the information and fill out the table below: C. What is a mutation? Type of mutation Description Substitution Deletion Insertion Frameshift **Exit out of this webpage** Effect on resulting protein Topic: Replication A. Go to: http://nobelprize.org/educational_games/medicine/dna_double_helix/ B. Click on “Play DNA Game”; Click “next” and reading each page, continue to click next until you come to the game.; Click on organism #1 and match the base pairs as fast as you can! It is hard. Click Next and then click on each organism until you identify the one that belongs to chromosome #1; continue playing the game with the other two chromosomes, filling in the chart below. Be careful, other teams may get different results. Chromosome # 1 2 3 How many chromosomes? How many base pairs? How many genes? What is the organism?