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National
National Cancer Drugs Fund Application Form –
Bevacizumab with single agent Fluoropyramidine
for Advanced Colorectal Cancer
(1st line treatment)
Author(s)
David Thomson
Owner
Chemotherapy Clinical Reference Group
Version Control
Version Control
Date
Revision summary
Ver2.0
14 Jul 2014
Introduction of version control and addition of section re-SACT
and monitoring
Change to current version
Criteria
Changes
N/A
Introduction of version control and addition of section re-SACT and monitoring
National Cancer Drugs Fund – Application Form 14 July 2014
Page 1
Bevacizumab for Advanced Colorectal Cancer – 1st line combination with single agent fluoropyramidine
National Cancer Drugs Fund Application Form –
Bevacizumab with single agent Fluoropyramidine
for Advanced Colorectal Cancer
(1st line treatment)
Instructions to Consultants: Please fill in each section of the form electronically and save the
document with your own file name. [If you continue typing the boxes will enlarge to contain the text].
Please send electronically to ______________________. Please also send copies to your Trust’s link
accountant / corporate contracting team.
Security of Patient Identifiable Information: The patient will be identified by their NHS number only.
Please do not include any other patient identifiers for confidentiality reasons. All communication must be
sent to the Cancer Drugs Fund Office via secure e mail accounts: that is from an nhs.net account to the
____________ account.
Receipt of Application: The sender of the application will receive an acknowledgement, together with
details of the unique Cancer Drugs Fund reference.
Cancer Drugs Fund Policy: To check the status of a particular therapy please check the Cancer Drugs
Fund Policy at _________________
Applications will be subject to Clinical Audit arrangements.
BY TICKING THESE BOXES AND SUBMITTING THE APPLICATION THE CLINICIAN IS
CONFIRMING THE PATIENT MEETS ALL THE CRITERIA BELOW. IT SHOULD BE NOTED THAT
THE SACT DATASET WILL BE USED TO MONITOR THAT THESE CRITERIA ARE BEING MET.
Approved Treatment Required for Bevacizumab with single agent
fluoropyramidine for Advanced Colorectal Cancer – 1st line chemotherapy
TICK
All 6 conditions must be met
1. Application made by and first cycle of systemic anti-cancer therapy to be
prescribed by a consultant specialist specifically trained and accredited in
the use of systemic anti-cancer therapy
2. Advanced Colorectal Cancer
3. PS 0-2
4. Given in combination with a single agent fluoropyrimidine as 1st line
treatment
5. Patient assessed as unfit to receive combination oxaliplatin- or irinotecanbased combination chemotherapy
6. No previous treatment with Bevacizumab
Note: Bevacizumab is not approved for use as a single agent maintenance therapy on
its own.
Note: No treatment breaks of more than 4 weeks beyond the expected cycle length are
allowed (to allow any toxicity of current therapy to settle or in the case of intercurrent
co-morbidities)
Consultant Approval (email authority)
National Cancer Drugs Fund – Application Form 14 July 2014
Page 2
Bevacizumab for Advanced Colorectal Cancer – 1st line combination with single agent fluoropyramidine
Patient Consent Obtained (date of letter – copy to be retained on patient file)
National Cancer Drugs Fund – Application Form 14 July 2014
Page 3
Bevacizumab for Advanced Colorectal Cancer – 1st line combination with single agent fluoropyramidine
Proposed Start Date for Therapy (add clinic date)*:
Consultant details*
(including signature or
email confirmation)
Name:
Hospital:
Address:
Post Code:
Telephone:
Nhs.net
Trust Pharmacist details of the Trust where
the patient will be
treated*
Mandatory - NHS No*:
Mandatory – Patients
date of birth*
Optional – Hospital No.
Clinical Commissioning
Group*
Patient’s GP*
(name, address,
telephone)
Name:
Hospital:
Address:
Post Code:
Telephone:
Nhs.net
NHS No:
DOB:
Hospital No:
CCG Name:
Name:
Address:
Post Code:
ICD-10 Code (please tick
relevant box)*
C18 - Malignant neoplasm of colon
C19 - Malignant neoplasm of rectosigmoid junction
C20 - Malignant neoplasm of rectum
HRG Code
Completion of items marked with * is mandatory. Failure to complete these items may
mean that payment is not made.
National Cancer Drugs Fund – Application Form 14 July 2014
Page 4
Bevacizumab for Advanced Colorectal Cancer – 1st line combination with single agent fluoropyramidine