Download LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – ZOOLOGY
THIRD SEMESTER – APRIL 2010
BT 3901 - MEDICAL MICROBIOLOGY
Date & Time: 28/04/2010 / 9:00 - 12:00 Dept. No.
Max. : 100 Marks
PART A
(20 marks)
Answer All questions
I Choose the Correct Answer
(5 x 1 = 5 marks)
01. Match A) H1N1 B) HAV C) pus D) Protozoan
with i) gonococci ii) tamiflu iii) Trichomoniasis iv) liver
a) A-ii, B-iv, C-iii, D) i
b) A-ii, B-i, C-iv, D) iii
c) A-ii, B-iii, C-i,
D) iv
d) A-ii, B-iv, C - i, D - iii
02. Which among the following is a differential staining?
a. acidfast
b. capsular
c. flagellar
d. methylene blue
03. Statement A: The causal organism of Typhus fever belongs to Rickettsia group.
Statement B: It is an obligate intracellular parasite.
a) Statement A is correct, but B is incorrect
b) Statement A is incorrect, but B is correct
c) Both A and B are correct
d) Both A and B are incorrect
04. An antiviral agent used in the treatment of infectious disease is:
a. interleukin
b. interphase
c. interferon
d. interlysin
05. Hyaluronidase is otherwise known as ___________ factor:
a. slicing
b. spreading
c. virulence
d. toxic
II State whether the following are True or False. If false, given reason (5 x 1 = 5 marks)
06. Disinfection refers to the complete destruction of all forms of microbial life.
07. Portal of entry varies with the pathogens.
08. Precipitation is the most striking of all test-tube antigen-antibody reactions.
09. Histoplasmosis is a dermatophytic infection caused by a fungus.
10. Clostridium tetani is a gram negative, obligate aerobic spore forming bacillus.
III. Complete the following
(5 x 1 = 5 marks)
11. Application of ionizing radiation to sterilize biological materials is called_______ ______
12. Those who are infected but have not yet developed the symptoms are called___________
____________
13.Wasserman test is an example for ____________ _____________ test.
14. Candidiasis is caused by___________ _____________.
15. The trade name of Anthrax __________ Adsorbed is _________.
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IV. Answer all, each in about 50 words
16. Write down Koch’s postulates.
17. Name the two types of carriers of pathogen.
18. Distinguish between transient and resident flora.
19. Mention any two characterestics of chemotherapeutic agents
20. Enumerate any two points about madcow disease.
(5 x 1 = 5 marks)
PART B
(5 x 8 = 40 marks)
Answer any five, each within 350 words only. Draw diagrams and flowcharts wherever
necessary.
21. Write about the importance of halogens and heavy metals in the control of microbes.
22. Distinguish between exotoxins and endotoxins. Give one example each.
23.Explain the principle and applications of agglutination and precipitation.
24. Discuss the causal organism, symptoms and treatment of tuberculosis.
25. Write about the three types of anthrax. Add a note on its lab. diagnosis.
26. Expand the following with a foot notes each:
a) LAF
b) NMF
c) TPCF
d) NMEP
27. Define the following:
a) Fumigation b) Inter-host survival period c) Complement d) Impetigo
28. Distinguish between: (any two differences each)
a) Causal organism of amoebiasis and trichomoniasis
b) Taenia paedis and Taenia capitis
c) Acute and Latent infection
d) d) Active and passive immunity
PART C
(2 x 20 = 40 marks)
Answer the following, each within 1500 words only. Draw diagrams and flowcharts wherever
necessary.
29. Give an account of the following physical agents used in the control
of microbes:
i) Moist heat
ii) dry heat
iii) radiation
iv) filtration
OR
b) Write notes on
i) Enzymes as virulent factors
ii) Sulphonamides
30. a) Compare and contrast syphilis and Gonorrhea based on causal organism, incubation
period, symptoms and treatment.
OR
b) Explain the following:
i) Life cycle of Malarial parasite
ii) HIV – structure and symptoms
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