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Transcript
Patient Findings Medications History AHer 58-year-old medications woman were presented levothyroxine, her A woman complains A58-year-old urine dipstick was positive to forof hydroxychloroquine, primary care physician pravastatin, after several and dizziness, anorexia, dry mouth, leukocyte esterase and nitrites. The of dizziness, alendronate. anorexia, increased thirst, and frequent patient given adry Herdays history was notable for cutaneous Her family history included oral mouth, increased thirst, and frequent urination. Shefohad alsoosteoporosis, had a fever. prescription ciprofloxacin forand a lupus, hyperlipidemia, bladder cancer in her mother, Graves' urination. She had also had a fever She reported no pain in her abdomen, urinary tract infection. 3 days later, frequent urinary tract infections, a left disease in two sisters, and reported “get back, and nothat cough, orwould diarrhea. patient reported weakness and oophorectomy for afood benign cyst, and hemochromatosis in one sister, and stuck” when she was swallowing. She dizziness. Her supine blood pressure primary hypothyroidism, diagnosed a idiopathic thrombocytopenic purpura reported no mm pain in her abdomen, back, was 120/80 Hg, and pulse was 88. year earlier sistershortness of or flank andinnoone cough, breath, diarrhea, or dysuria Family History Patient History Symptoms Family Medications Findings Symptoms Putting the Pieces Together at Point of Impact Can Be Life Changing 0 difficulty swallowing fever dry mouth thirst anorexia frequent urination dizziness no abdominal pain no back pain no cough no diarrhea Oral cancer Bladder cancer Hemochromatosis Purpura Graves’ Disease (Thyroid Autoimmune) cutaneous lupus osteoporosis hyperlipidemia frequent UTI hypothyroidism Alendronate pravastatin levothyroxine hydroxychloroquine urine dipstick: leukocyte esterase supine 120/80 mm HG heart rate: 88 bpm urine culture: E. Coli Diagnosis Models Confidence Renal failure UTI Diabetes Influenza hypokalemia Esophagitis • Extract Symptoms from record Most Most Confident ConfidentDiagnosis: Diagnosis:UTI Diabetes Esophagitis Influenza • Use paraphrasings mined from text to handle • Identify • •Extract Extract negative Patient Family Medications Symptoms History alternate phrasings and variants •••Use Reason Medical • Use with database Taxonomies mined of relations drug to generalize side-effects to explain medical away Perform broad search for possible diagnoses ••conditions Together, symptoms multiple to the (thirst granularity diagnoses is consistent used may by best w/ the UTI) explain models Score Confidence in each diagnosis based on symptoms evidence so far • Extract Findings: Confirms that UTI was present © 2011 IBM Corporation