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Module Name MI4M02 Molecular and Cell Biology Module Credit Value 10 ECTS Module Coordinator Dr. Ursula Bond Lecturers Prof. Charles Dorman Dr. Ursula Bond Dr. Alastair Fleming Dr. Kim Roberts Contact Hours 20 lectures Recommended Reading List for self guided study Students will be provided with primary research articles and scientific reviews on specialised research topics for self-guided study. Short Content Overview This module builds on the core concepts of bacterial and eukaryotic gene expression studied in the Junior Sophister year and introduces students to "up to the minute" developments in research in this area. Lecture topics include, the dynamic genomes of bacteria and eukaryotic organisms with an emphasis on yeasts, the compaction and reorganisation of chromatin and the bacterial nucleoid during gene expression, chromatin modification, biogenesis of RNA, including RNA polymerase II transcription, RNA processing and export form the nucleus. Lectures on the interaction of viruses with the host cell machines are provided and students are introduced to the world of small RNA and the role of small RNAs in viral pathogenesis. Tutorials on problem solving and data analysis are also provided in this module.