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Endometrial Cancer By: Maureen Jaminal BIOL 316 What is Endometrial Cancer? www.med-ars.it What is Endometrial Cancer? Cause The exact cause is unknown. Estrogen Risk Factors Sex, Age, Class, Race, Family History Irregular menstrual periods Early first menstruation or late menopause Low parity or nulliparity Infertility Obesity Diabetes Hypertension Estrogen replacement therapy and/or Tamoxifen Symptoms Unusual Vaginal Spotting Bleeding Discharge Pain in the pelvic region Presence of a lump Diagnosis Treatments The stage of cancer is determined. International Federation of Gynecology and Obstetrics (FIGO) adopted a staging and grading (G1-G3) system. FIGO stages are: Stage I. Cancer is limited to the uterus. 70% Stage II. Cancer involves the uterus and cervix. 10-15% Stage III. Cancer has spread out of the uterus but restricted to pelvic region. Stage IV. Cancer has spread to the bladder, bowel, or other distant locations. Treatments Treatments Radiation Therapy Chemotherapy Hormonal Therapy Alternatives Prognosis Since it is possible to detect endometrial cancer early, the chances of curing it are excellent! Survival Rates 5% 40% 90% 60% Stage I Stage II Stage III Stage IV Prevention Women report any abnormal vaginal bleeding or discharge to the doctor. Controlling obesity, blood pressure, and diabetes help reduce risk. Using birth control helps prevent endometrium cancer. Taking medication that produces estrogen ask about receiving progesterone. If you are at risk, get screened regularly. The End