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RESEARCH Davis, R.H. mutants Lethality of associated with Neurosporo o factor from NOTES orginine In wild lacking type. yielded ratios after factor, isolation derived org-I2 mutant. We citrulline, of have and probably 2 wild: to medium from the been able ornithine, activity “lethal org-12. Another absolute ot not been able UM-300. were consistent o normal to show by disappearance from of It is not concentrations yet to uptake I should or other mutants, on Emerson, S. of genetic Genetic isolations characters from are characters of the and UM-300 if too miserable recover strains hyphal nature and Genetics, to our was in stock able to of derepression. analyzed press, the pathway of wild rate system th an and extent latter UM-300. is the l/4 rate wild of elevation The double “lethal of could destruction). type; mechanism per ml mutant, ” progeny not be arginine this of arginine an arginine concentration be noted thot I mg orginine is ornithine I low arginine normal little of arginine, The exogenously-provided or o rapid in our very that another with the basis of high of I high to gives of regularly grew a low level activity. endogenously-synthesized UM-300 73a suggested associated is denoted arg-12 mutant and Davis crosses type but ratio (arg-m or destruction) mutants 1963), germinate, described t o on UM-300 transport in Neurospora (arg-12: On the segregation and effects thot loss system UM-300 possible, in We measured was mycelio hove when is deficient, medium will of the slime appreciate osmotic -unknown, without OS, fz, and -hyphal growth: with persistent plasmodioid (OS, From slime publication only and support test the the cultures it separated phenotypes. for, the (see Pub. cleanly IR, which was mutant), and has extremely by slime flows wild type. with arginine were between (Proc. XI Because to cite Int. Cong. more data this note Botany, supplied Neurospora to the Fungal Information 1962) little with was Conknown parental in spontaneous poor surface instead of germ the germination growth tubes in inherited The parent (sg, of slime), linkage Arcospore habit7 but of the genes irradiated write University that three independently of the slime phenotype. present Neither in studied of together It is now known persistent expression group Stadler above.) 950, internal relationships wishing of slime Center acid o normal genetic permission.--Deportment time the experiences investigators NAS-NRC germinate does with ference, linkage than amino comparable thot Stock that other poorly had ond Genetics o morphological heat activation, sg usually forms for except with hyphal yet i nsufficient more have only case reported by D. R. with the one described be cited At the strains (A recent similarities slime phenotype orginine; workers to exchange note to concentrate arginine, since some units os external concentrations. concentrates I should the inability in the is for other crassa. are: is scheduled of transcarbamylase ml. The progeny for the “Ietholity”when arginine imperfect whether soon, and that Michigan. (fz , linkage group unknown, germinates carrying class the hypothesis by transport which heterocaryons essential to, involved isolates the and to know Neurosporo basis the slower and other mutants of this type. vol. I, p. 52) appears to hove variant characters the is ornithine, interested be available oil UM-300 has o complete hove not been measured specific for more recent results, of Michigan, Ann Arbor, --fuzzy group of an on analysis arg-12. be UM-300 Genetics, in (through medium whether arginine how the is much mutants carrying These results suggest that is not the case. It should UM-300, clear of is it known will the the medium. destruction growth mutants uptake such was for mutant (because that cross of o strain with Thwaites, by way x 74o concentration be concentrated added to that rapid crosses and lost of ornithine stock used is abnormal in having o high ornithine transcorbamylase responsible in could regard factor The levels, of o 7% The observed crossed to These results ” course pgm arginine per was responsible arginine progeny observed. maintained the low ” category UM-300, when 200 parent, of the was I “lethal. containing wild type to show that the 73a and also in having o consequence transcarbamylase, I arg-12: the eventually change some ---os fz phenotypes. of such in a --No. sg isolates it has been possible by vegetative selection to No genetic difference has yet been established between A fuller account with descriptions of the unit fz sg isolates. 3, Vol. 34 (1963/64) of Genetico. (Supported in port by on